1,079 research outputs found
Some Remarks on the Question of Charge Densities in Stationary-Current-Carrying Conductors
Recently, some discussions arose as to the definition of charge and the value
of the density of charge in stationary-current-carrying conductors. We stress
that the problem of charge definition comes from a misunderstanding of the
usual definition. We provide some theoretical elements which suggest that
positive and negative charge densities are equal in the frame of the positive
ions.Comment: 14 pages, TeX, macro newsym.tex include
Habitat corridors facilitate genetic resilience irrespective of species dispersal abilities or population sizes
Corridors are frequently proposed to connect patches of habitat that have become isolated due to humanâmediated alterations to the landscape. While it is understood that corridors can facilitate dispersal between patches, it remains unknown whether corridors can mitigate the negative genetic effects for entire communities modified by habitat fragmentation. These negative genetic effects, which include reduced genetic diversity, limit the potential for populations to respond to selective agents such as disease epidemics and global climate change. We provide clear evidence from a forwardâtime, agentâbased model (ABM) that corridors can facilitate genetic resilience in fragmented habitats across a broad range of species dispersal abilities and population sizes. Our results demonstrate that even modest increases in corridor width decreased the genetic differentiation between patches and increased the genetic diversity and effective population size within patches. Furthermore, we document a tradeâoff between corridor quality and corridor design whereby populations connected by highâquality habitat (i.e., low corridor mortality) are more resilient to suboptimal corridor design (e.g., long and narrow corridors). The ABM also revealed that species interactions can play a greater role than corridor design in shaping the genetic responses of populations to corridors. These results demonstrate how corridors can provide longâterm conservation benefits that extend beyond targeted taxa and scale up to entire communities irrespective of species dispersal abilities or population sizes.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/111750/1/eva12255.pd
Superconducting-coil--resistor circuit with electric field quadratic in the current
It is shown for the first time that the observed [Phys. Lett. A 162 (1992)
105] potential difference Phi_t between the resistor and the screen surrounding
the circuit is caused by polarization of the resistor because of the kinetic
energy of the electrons of the superconducting coil. The proportionality of
Phi_t to the square of the current and to the length of the superconducting
wire is explained. It is pointed out that measuring Phi_t makes it possible to
determine the Fermi quasimomentum of the electrons of a metal resistor.Comment: 2 pages, 1 figur
The Millennium Galaxy Catalogue: the photometric accuracy, completeness and contamination of the 2dFGRS and SDSS-EDR/DR1 data sets
The Millennium Galaxy Catalogue (MGC) is a deep (ÎŒB,lim = 26 mag arcsecâ2), wide-field, charge-coupled device imaging survey, covering 37.5 deg2. The MGC survey region is completely contained within the Two-Degree Field Galaxy Redshift Survey (2dFGRS) and the Sloan Digital Sky Survey Early Data Release (SDSS-EDR). We compare the photometry and completeness of the 2dFGRS and the SDSS-EDR with the MGC over the range 16 < B < 20 mag. We have also undertaken a photometric comparison to SuperCosmos (SCOS) and the Sloan Digital Sky Survey First Data Release (SDSS-DR1). We find that BMGCâB2dF = (0.035 ± 0.005) mag with an uncertainty of 0.142 mag per galaxy; BMGCâBSCOS = (0.032 ± 0.005) mag with an uncertainty of 0.108 mag; BMGCâBSDSS-EDR = (0.032 ± 0.005) mag with an uncertainty of 0.094 mag; and BMGCâBSDSS-DR1 = (0.039 ± 0.005) mag with an uncertainty of 0.086 mag. We find that high surface brightness 2dFGRS galaxies are systematically too faint, which leads to a significant scale error in magnitude. This effect is significantly reduced with the SCOS photometry. In the SDSS there is a weak non-linear scale error, which is negligible for faint galaxies. Low surface brightness galaxies in the SDSS are systematically fainter, consistent with the relative shallowness of this survey. We find that the 2dFGRS catalogue has (5.2 ± 0.3) per cent stellar contamination, (7.0 ± 0.4) per cent of objects resolved into two or more by the MGC, and is (8.7 ± 0.6) per cent incomplete compared to the MGC. From our all-object spectroscopic survey we find that the MGC is itself misclassifying (5.6 ± 1.3) per cent of galaxies as stars, and hence the 2dFGRS misses (14.3 ± 1.4) per cent of the galaxy population. The SDSS-EDR galaxy catalogue has (1.3 ± 0.1) per cent stellar contamination and (5.3 ± 1.0) per cent of galaxies misclassified as stars, with (0.18 ± 0.04) per cent of objects resolved into two or more by the MGC, and is (1.8 ± 0.1) per cent incomplete compared to the MGC. The total fraction of galaxies missing from the SDSS-EDR galaxy catalogue to BMGC = 20 mag, from incompleteness and misclassification, is (7.1 ± 1.0) per cen
Histone deacetylase adaptation in single ventricle heart disease and a young animal model of right ventricular hypertrophy.
BackgroundHistone deacetylase (HDAC) inhibitors are promising therapeutics for various forms of cardiac diseases. The purpose of this study was to assess cardiac HDAC catalytic activity and expression in children with single ventricle (SV) heart disease of right ventricular morphology, as well as in a rodent model of right ventricular hypertrophy (RVH).MethodsHomogenates of right ventricle (RV) explants from non-failing controls and children born with a SV were assayed for HDAC catalytic activity and HDAC isoform expression. Postnatal 1-day-old rat pups were placed in hypoxic conditions, and echocardiographic analysis, gene expression, HDAC catalytic activity, and isoform expression studies of the RV were performed.ResultsClass I, IIa, and IIb HDAC catalytic activity and protein expression were elevated in the hearts of children born with a SV. Hypoxic neonatal rats demonstrated RVH, abnormal gene expression, elevated class I and class IIb HDAC catalytic activity, and protein expression in the RV compared with those in the control.ConclusionsThese data suggest that myocardial HDAC adaptations occur in the SV heart and could represent a novel therapeutic target. Although further characterization of the hypoxic neonatal rat is needed, this animal model may be suitable for preclinical investigations of pediatric RV disease and could serve as a useful model for future mechanistic studies
A semi-parametric approach to estimate risk functions associated with multi-dimensional exposure profiles: application to smoking and lung cancer
A common characteristic of environmental epidemiology is the multi-dimensional aspect of exposure patterns, frequently reduced to a cumulative exposure for simplicity of analysis. By adopting a flexible Bayesian clustering approach, we explore the risk function linking exposure history to disease. This approach is applied here to study the relationship between different smoking characteristics and lung cancer in the framework of a population based case control study
The Millennium Galaxy Catalogue: 16 < B_MGC < 24 galaxy counts and the calibration of the local galaxy luminosity function
The Millennium Galaxy Catalogue (MGC) is a 37.5 deg^2, medium-deep, B-band
imaging survey along the celestial equator, taken with the Wide Field Camera on
the Isaac Newton Telescope. The survey region is contained within the regions
of both the Two Degree Field Galaxy Redshift Survey (2dFGRS) and the Sloan
Digital Sky Survey Early Data Release (SDSS-EDR). The survey has a uniform
isophotal detection limit of 26 mag arcsec^-2 and it provides a robust,
well-defined catalogue of stars and galaxies in the range 16 <= B_MGC < 24 mag.
Here we describe the survey strategy, the photometric and astrometric
calibration, source detection and analysis, and present the galaxy number
counts that connect the bright and faint galaxy populations within a single
survey. We argue that these counts represent the state of the art and use them
to constrain the normalizations (phi*) of a number of recent estimates of the
local galaxy luminosity function. We find that the 2dFGRS, SDSS Commissioning
Data (CD), ESO Slice Project, Century Survey, Durham/UKST, Mt Stromlo/APM,
SSRS2, and NOG luminosity functions require a revision of their published phi*
values by factors of 1.05 +/- 0.05, 0.76 +/- 0.10, 1.02 +/- 0.22, 1.02 +/-
0.16, 1.16 +/- 0.28, 1.75 +/- 0.37, 1.40 +/- 0.26 and 1.01 +/- 0.39,
respectively. After renormalizing the galaxy luminosity functions we find a
mean local \bj luminosity density of j_{b_J} = (1.986 +/- 0.031) x 10^8 h
L_{\odot} Mpc^-3.Comment: 20 pages, LaTeX, 20 Postscript figures (some low resolution), MNRAS,
in press; considerably revised versio
Early Fasting Is Long Lasting: Differences in Early Nutritional Conditions Reappear under Stressful Conditions in Adult Female Zebra Finches
Conditions experienced during early life can have profound effects on individual development and condition in adulthood. Differences in nutritional provisioning in birds during the first month of life can lead to differences in growth, reproductive success and survival. Yet, under natural conditions shorter periods of nutritional stress will be more prevalent. Individuals may respond differently, depending on the period of development during which nutritional stress was experienced. Such differences may surface specifically when poor environmental conditions challenge individuals again as adults. Here, we investigated long term consequences of differences in nutritional conditions experienced during different periods of early development by female zebra finches (Taeniopygia guttata) on measures of management and acquisition of body reserves. As nestlings or fledglings, subjects were raised under different nutritional conditions, a low or high quality diet. After subjects reached sexual maturity, we measured their sensitivity to periods of food restriction, their exploration and foraging behaviour as well as adult resting metabolic rate (RMR). During a short period of food restriction, subjects from the poor nutritional conditions had a higher body mass loss than those raised under qualitatively superior nutritional conditions. Moreover, subjects that were raised under poor nutritional conditions were faster to engage in exploratory and foraging behaviour. But RMR did not differ among treatments. These results reveal that early nutritional conditions affect adult exploratory behaviour, a representative personality trait, foraging and adult's physiological condition. As early nutritional conditions are reflected in adult phenotypic plasticity specifically when stressful situations reappear, the results suggest that costs for poor developmental conditions are paid when environmental conditions deteriorate
Omnichannel Value Chain: Mapping Digital Technologies for Channel Integration Activities
In order to provide a seamless customer experience, researchers and practitioners have proposed creation of an omnichannel retailing environment by integrating online and offline channels. Channel integration necessitates use of digital technologies and there are myriads of technological solutions available. However, retailers are struggling with selection and implementation of suitable technologies to add value through channel integration. Despite the strong practical need, this issue has not been effectively addressed in the academic literature. This paper presents an omnichannel value chain underpinned by Porterâs value chain model. We identify ten channel integration activities for value creation by carrying out a synthesis of current research on omnichannel retailing. Enabling digital technologies are then mapped to these activities using technology implementation examples and provide a guideline for retailers to select appropriate technologies for the identified value creation activities
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