Psychologicke faktory pri lecbe sterility pomoci in vitro fertilizace.

The aim of the first and second parts of the thesis was to study the gender specific emotional impact of in-vitro fertilisation (IVF) and any possible influence due to the type of diagnosis, duration of infertility and number of cycles. In the third part we studied the influence of psychological stress on the outcome of IVF treatment. The prospective clinical study was curried out on 66 couples before the start of controlled ovarian hyperstimulation in the IVF program. Successful couples (25) were examined again after the ultrasound diagnosis of viable pregnancy in the uterus. We used following psychometric tests: State-Trait Anxiety Inventory (STAI), Beck's Depression Inventory (BDI), Interpersonal Checklist (ICL) and Dusin Frustration Test. We obtained following resuslts: Statistically significantly highest scores of depression and trait anxiety were in the group of women before the second IVF cycle and with the duration of infertility 4 - 6 years (compared with groups before the first cycle and third and more cycle, resp. with the duration of infertility 1 - 3 years and more than 7 years). We didn't find any differences in scores of state anxiety and degree of frustration between these groups. Between these groups of men were not any differences.Available from STL Prague, CZ / NTK - National Technical LibrarySIGLECZCzech Republi

Effect of Energy Expenditure And Physical Activity on The Outcomes of Assisted Reproduction Treatment

It is still not definitely resolved whether being physically active has any impact on the success of assisted reproduction treatment. To this end, this study used the International Physical Activity Questionnaire short form (IPAQ-sf). Data from the IPAQ-sf were classified into three categories: low, moderate and high physical activity as defined by the IPAQ working group. The subjects in the study were grouped according to their physical activity levels during treatment. None of the subjects met the criteria for high physical activity. The tow activity group consisted of 68 women whereas moderate activity group consisted of 63 women. The study showed that women undergoing assisted reproduction treatment significantly decreased their activity level during the treatment period (P < 0.05). However, women who. were physically more active were more likely to have an increased implantation rate and a live birth. (C) 2009, Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.WoSScopu

Different subsets of newborn granule cells: a possible role in epileptogenesis?

Several factors, including epileptic seizures, can strongly stimulate ongoing neurogenesis in the adult hippocampus. Although adult-born granule cells generated after seizure activity have different physiological properties from their normal counterparts, they integrate into the existing, mature network of the adult hippocampal dentate gyrus. However, the exact role of the neurogenic response during epilepsy and its possible involvement in epileptogenesis have remained elusive. Here, we discuss recent studies shedding new light on the interplay between epilepsy and neurogenesis, and try to explain discrepancies in this literature by proposing seizure severity-dependent induction of two subsets of newborn cells with different properties. We hypothesise that a low seizure intensity would stimulate neurogenesis to a 'physiological plasticity' level and have few pathological consequences. In contrast, a high initial seizure intensity may induce a specific subset of altered and/or ectopically located new granule cells with different electrophysiological properties that could initiate hyperexcitatory recurrent networks that could, in turn, contribute to chronic epilepsy. This hypothesis may clarify previously contradictory data in the literature, and could thereby aid in our understanding of the role of neurogenesis in epileptogenesis, and open up promising avenues for therapeutic intervention