70 research outputs found

    Collective narcissism: Political consequences of investment of self-worth into an ingroup’s image.

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    This article proposes a new theoretical framework for the reviewed state-of-the-art research on collective narcissism–the belief that the ingroup’s exceptionality is not sufficiently appreciated by others. Collective narcissism is interpreted as the investment of an undermined sense of self-esteem into the belief in the ingroup’s entitlement to privilege. Collective narcissism lies in the hard of populist rhetoric. The belief in ingroup’s exceptionality compensates for a lack of self-worth, leaving collective narcissists hyper-vigilant to signs of threat to the ingroup’s position. People endorsing the collective narcissistic belief are prone to biased perceptions of intergroup situations and to conspiratorial thinking. They retaliate to imagined provocations against the ingroup but sometimes overlook real threats. They are prejudiced and hostile. Deficits in emotional regulation, hostile attribution bias and vindictiveness lie behind the robust link between collective narcissism and intergroup hostility. Interventions that support the regulation of negative emotions, such as experiencing self-transcendent emotions, decrease the link between collective narcissism and intergroup hostility and offer further insights into the nature of collective narcissism

    Coulomb excitation of 222Rn

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    The nature of quadrupole and octupole collectivity in 222Rn was investigated by determining the electricquadrupole (E2) and octupole (E3) matrix elements using subbarrier, multistep Coulomb excitation. The radioactive 222Rn beam, accelerated to 4.23 MeV/u, was provided by the HIE-ISOLDE facility at CERN. Data were collected in the Miniball gamma -ray spectrometer following the bombardment of two targets, 120Sn and 60Ni. Transition E2 matrix elements within the ground-state and octupole bands were measured up to 10 h over bar and the results were consistent with a constant intrinsic electric-quadrupole moment, 518(11) e fm2. The values of the intrinsic electric-octupole moment for the 0+ -> 3- and 2+ -> 5- transitions were found to be respectively -210 e fm3 and 2300+300-500 e fm3 while a smaller value, 1200+500-900 e fm3, was found for the 2+ -> 1- transition. In addition, four excited non-yrast states were identified in this work via gamma -gamma coincidences.Peer reviewe

    Quadrupole collectivity in Ca 42 from low-energy Coulomb excitation with AGATA

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    A Coulomb-excitation experiment to study electromagnetic properties of Ca42 was performed using a 170-MeV calcium beam from the TANDEM XPU facility at INFN Laboratori Nazionali di Legnaro. γ rays from excited states in Ca42 were measured with the AGATA spectrometer. The magnitudes and relative signs of ten E2 matrix elements coupling six low-lying states in Ca42, including the diagonal E2 matrix elements of 21+ and 22+ states, were determined using the least-squares code gosia. The obtained set of reduced E2 matrix elements was analyzed using the quadrupole sum rule method and yielded overall quadrupole deformation for 01,2+ and 21,2+ states, as well as triaxiality for 01,2+ states, establishing the coexistence of a weakly deformed ground-state band and highly deformed slightly triaxial sideband in Ca42. The experimental results were compared with the state-of-the-art large-scale shell-model and beyond-mean-field calculations, which reproduce well the general picture of shape coexistence in Ca42

    Superdeformed and Triaxial States in Ca 42

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    Shape parameters of a weakly deformed ground-state band and highly deformed slightly triaxial sideband in ^{42}Ca were determined from E2 matrix elements measured in the first low-energy Coulomb excitation experiment performed with AGATA. The picture of two coexisting structures is well reproduced by new state-of-the-art large-scale shell model and beyond-mean-field calculations. Experimental evidence for superdeformation of the band built on 0_{2}^{+} has been obtained and the role of triaxiality in the A∼40 mass region is discussed. Furthermore, the potential of Coulomb excitation as a tool to study superdeformation has been demonstrated for the first time

    Sex- and age-related differences in the management and outcomes of chronic heart failure: an analysis of patients from the ESC HFA EORP Heart Failure Long-Term Registry

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    Aims: This study aimed to assess age- and sex-related differences in management and 1-year risk for all-cause mortality and hospitalization in chronic heart failure (HF) patients. Methods and results: Of 16 354 patients included in the European Society of Cardiology Heart Failure Long-Term Registry, 9428 chronic HF patients were analysed [median age: 66 years; 28.5% women; mean left ventricular ejection fraction (LVEF) 37%]. Rates of use of guideline-directed medical therapy (GDMT) were high (angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, beta-blockers and mineralocorticoid receptor antagonists: 85.7%, 88.7% and 58.8%, respectively). Crude GDMT utilization rates were lower in women than in men (all differences: P\ua0 64 0.001), and GDMT use became lower with ageing in both sexes, at baseline and at 1-year follow-up. Sex was not an independent predictor of GDMT prescription; however, age >75 years was a significant predictor of GDMT underutilization. Rates of all-cause mortality were lower in women than in men (7.1% vs. 8.7%; P\ua0=\ua00.015), as were rates of all-cause hospitalization (21.9% vs. 27.3%; P\ua075 years. Conclusions: There was a decline in GDMT use with advanced age in both sexes. Sex was not an independent predictor of GDMT or adverse outcomes. However, age >75 years independently predicted lower GDMT use and higher all-cause mortality in patients with LVEF 6445%

    A High-Resolution Study of the 110Tc → 110Ru → 110Rh → 110Pd Decay Chain with the GRETINA Array

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    Spectroscopic data, such as precise γ-ray branching and E2/M1 multipole-mixing ratios, provide vital constraints when performing multi-dimensional Coulomb-excitation analyses. Consequently, as part of our new Coulomb-excitation campaign aimed at investigating the role of exotic non-axial (triaxial) deformations in the unstable refractory Ru-Mo isotopes, additional beta-decay data was obtained. These measurements make use of ANL's CARIBU facility, which provides intense beams of radioactive refractory isotopes along with the excellent efficiency and angular resolution of the GRETINA γ-ray tracking array. In this article, we report on the analysis of the A = 110 decay chain, focussing on the identification of previously unreported states in 110Ru following the decay of 110Tc

    Detection of O6-Carboxymethyl-2'-deoxyguanosine in DNA Following Reaction of Nitric Oxide with Glycine and in Human Blood DNA Using a Quantitative Immunoslot Blot Assay

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    Previous research has shown that a range of nitrosated glycine derivatives react with DNA to form O6-carboxymethylguanine and O6-methylguanine DNA adducts [Harrison et al. (1999) Chem. Res. Toxicol. 12, 106-111). Nitrosated glycine derivatives may be formed in the gastrointestinal tract from the reaction of dietary glycine with nitrosating agents. The aim of this study was to further investigate the role of dietary glycine in the formation of O6-guanine adducts at physiologically relevant concentrations. In vitro studies were performed by reacting 10 M to 50 mM glycine with nitric oxide in the presence of oxygen. An HPLC assay was developed to measure the resulting nitrosated glycine derivative, diazoacetate anion. The amount of nitrosating agent present in the reaction mixture was determined by colorimetric measurement of nitrite, the hydrolysis product of N2O3. Diazoacetate anion formation depended linearly on glycine concentration. Solutions of nitrosated glycine reacted with 2'-deoxyguanosine and calf thymus DNA to give O6-carboxymethyl-2'-deoxyguanosine and, at high concentrations of glycine and nitric oxide, O6-methyl-2'-deoxyguanosine. At physiological concentrations of glycine and nitric oxide, diazoacetate anion was not detectable. Studies with synthetic diazoacetate anion showed that concentrations <14 M did not give detectable O6-carboxyethylguanine in DNA, even when a sensitive immunoslot blot assay was used. However, O6-carboxymethylguanine was detected in human blood DNA samples obtained from three volunteers consuming a standardized high meat diet, using the immunoslot blot assay. O6-Carboxymethylguanine levels ranged from 35 to 80 (detection limit = 15) O6-carboxymethylguanine per 108 bases. These studies provide further evidence that nitrosated amino acids may be risk factors for gastrointestinal tract cancers
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