Not-for-profit organizations audit manual, Volume 2

https://egrove.olemiss.edu/aicpa_guides/2179/thumbnail.jp

Not-for-profit organizations audit manual, Volume 1

https://egrove.olemiss.edu/aicpa_guides/2178/thumbnail.jp

An implementation and analysis of a randomized distributed stack

Due to the character of the original source materials and the nature of batch digitization, quality control issues may be present in this document. Please report any quality issues you encounter to [email protected], referencing the URI of the item.Includes bibliographical references (leaf 25).This thesis presents an algorithm for a randomized distributed stack, a coded simulator for examining its behavior, and an analysis of data collected from simulations configured to investigate its performance in particular situations. This randomized distributed stack represents an experimental extension of the probabilistic quorum algorithm of Malki et al. [5,4] and the random regular register of Welch and Lee [3]. Employing the probabilistic quorum algorithm in the same manner as the random regular register, the randomized distributed stack stands to positively affect the load and availability of a system. Popping this randomized distributed stack, however, sometimes returns incorrect values. Analysis of the data assembled reveals two interesting conclusions: 1) as the number of uninterrupted pops increases, the variance of the pop success percentage increases, and 2) for a fixed quorum size percentage, a larger system of data servers yields a higher pop success percentage. Further research remains to fully characterize and generalize the behavior of the randomized distributed stack

“Now thrive the Armourers”: The Development of the Armourers’ Crafts and the Forging of Fourteenth-century London

This thesis ultimately seeks to understand how and why the London armourers came to be so closely associated with the politics and uprisings of London’s controversial mayor, John Northampton (1381-1383). However, because the armourers were not incorporated as a combined guild until 1453, this thesis must first analyse how the armourers developed as an industry, and how their workshop, household, and socio-industrial networks and organisations developed and helped to inform their political identities. This is the first time that the fourteenth-century London armourers have been rigorously examined as a collective of constituent specialist industries, and this thesis contributes to an understanding of how late medieval small crafts developed outside of guilds. Through examining armourers’ workshops, households, and socio-industrial networks, this thesis arrives at several important conclusions about the nature of the English industry in the fourteenth century which challenge existing scholarship. It finds evidence to explode scholarly myths that English armour was cheap and poorly made through lack of skill, that women did not participate in the industry, and that regulation of the industry was entirely imposed from outside. Finally, this study shows that the armourers were the most significant participants in the 1384 Mayoralty Riots because their workshop, household, and socio-industrial networks had all contributed to the development of a shared political identity, because Northampton’s opponent Nicholas Brembre attacked that identity, and because the Crown and City’s draconian policies towards the local armour market had grown increasingly severe prior to the riots. This thesis argues that the armourers’ political identity developed as an extension of their workshop, household, and socioindustrial identities and networks, and that each of these contributed to their overall organisational development outside of a guild structure

Selective timber management in the Douglas fir region

Gerald W. Williams Collectio

Effect of composition on the structure of lithium- and manganese-rich transition metal oxides

The choice of chemical composition of lithium- and manganese-rich transition metal oxides used as cathode materials in lithium-ion batteries can significantly impact their long-term viability as storage solutions for clean energy automotive applications. Their structure has been widely debated: conflicting conclusions drawn from individual studies often considering different compositions have made it challenging to reach a consensus and inform future research. Here, complementary electron microscopy techniques over a wide range of length scales reveal the effect of lithium-to-transition metal-ratio on the surface and bulk structure of these materials. We found that decreasing the lithium-to-transition metal-ratio resulted in a significant change in terms of order and atomic-level local composition in the bulk of these cathode materials. However, throughout the composition range studied, the materials consisted solely of a monoclinic phase, with lower lithium content materials showing more chemical ordering defects. In contrast, the spinel-structured surface present on specific crystallographic facets exhibited no noticeable structural change when varying the ratio of lithium to transition metal. The structural observations from this study warrant a reexamination of commonly assumed models linking poor electrochemical performance with bulk and surface structure

Data analysis of the U–Pb geochronology and Lu–Hf system in zircon and whole-rock Sr, Sm–Nd and Pb isotopic systems for the granitoids of Thailand

© 2018 This data article provides zircon U–Pb and Lu–Hf isotopic information along with whole-rock Sm–Nd, Sr and Pb isotopic geochemistry from granitoids in Thailand. The U–Pb ages are described and the classification of crystallisation and inherited ages are explained. The petrography of the granitoid samples is detailed. The data presented in this article are interpreted and discussed in the research article entitled “Probing into Thailand's basement: New insights from U–Pb geochronology, Sr, Sm–Nd, Pb and Lu–Hf isotopic systems from granitoids” (Dew et al., 2018)

Targeting signaling and apoptotic pathways involved in chemotherapeutic drug-resistance of hematopoietic cells

A critical problem in leukemia as well as other cancer therapies is the development of chemotherapeutic drug-resistance. We have developed models of hematopoietic drug resistance that are based on expression of dominant-negative TP53 [TP53 (DN)] or constitutively-active MEK1 [MEK1(CA)] oncogenes in the presence of chemotherapeutic drugs. In human cancer, functional TP53 activity is often lost in human cancers. Also, activation of the Raf/MEK/ERK pathway frequently occurs due to mutations/ amplification of upstream components of this and other interacting pathways. FL5.12 is an interleukin-3 (IL−3) dependent hematopoietic cell line that is sensitive to doxorubicin (a.k.a Adriamycin). FL/Doxo is a derivative cell line that was isolated by culturing the parental FL5.12 cells in doxorubicin for prolonged periods of time. FL/Doxo + TP53 (DN) and FL/Doxo + MEK1 (CA) are FL/Doxo derivate cell lines that were infected with retrovirus encoding TP53 (DN) or MEK1 (CA) and are more resistant to doxorubicin than FL/Doxo cells. This panel of cell lines displayed differences in the sensitivity to inhibitors that suppress mTORC1, BCL2/BCLXL, MEK1 or MDM2 activities, as well as, the proteasomal inhibitor MG132. The expression of key genes involved in cell growth and drug-resistance (e.g., MDM2, MDR1, BAX) also varied in these cells. Thus, we can begin to understand some of the key genes that are involved in the resistance of hematopoietic cells to chemotherapeutic drugs and targeted therapeutics

Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post‐hoc analysis of a randomised controlled trial

Magnesium status and vitamin B6 intake have been linked to mental health and/or quality of life (QoL). In an 8‐week Phase IV randomised controlled study in individuals with low magnesemia and severe/extremely severe stress but who were otherwise healthy, greater stress reduction was achieved with magnesium combined with vitamin B6 than with magnesium alone. We present a previously unreported secondary analysis of the effect of magnesium, with and without vitamin B6, on depression, anxiety, and QoL. Adults with Depression Anxiety Stress Scales (DASS‐42) stress subscale score >18 were randomised 1:1 to magnesium + vitamin B6 combination (Magne B6®; daily dose 300 and 30 mg, respectively) or magnesium alone (Magnespasmyl®; daily dose 300 mg). Outcomes included changes from baseline in DASS‐42 depression and anxiety scores, and QoL (Short Form‐36 Health Survey). DASS‐42 anxiety and depression scores significantly improved from baseline to week 8 with both treatments, particularly during the first 4 weeks. Improvement in QoL continued over 8 weeks. Participants' perceived capacity for physical activity in daily life showed greater improvement with magnesium + vitamin B6 than magnesium alone (Week 4). In conclusion, magnesium supplementation, with or without vitamin B6, could provide a meaningful clinical benefit in daily life for individuals with stress and low magnesemia