Scientization, instrumentalization, and commodification of mindfulness in a professional services firm

Peer reviewe

High-resolution Emission Spectroscopy of the Ultrahot Jupiter KELT-9b: Little Variation in Day- and Nightside Emission Line Contrasts

The transmission spectrum of the ultrahot Jupiter KELT-9b ($T_{eq}$ $\sim$ 4000 K) exhibits absorption by several metal species. We searched for atomic and molecular lines in its emission spectrum by observing partial phase curves with the CARMENES spectrograph ($R$ $\sim$ 80,000 $-$ 95,000). We find evidence for emission by Si I in the atmosphere of KELT-9b for the first time. Additionally we find evidence for emission by Mg I and Ca II, which were previously detected in transmission, and confirmed earlier detections of Fe I emission. Conversely, we find no evidence for dayside emission from Al I, Ca I, Cr I, FeH, Fe II, K I, Li I, Mg II, Na I, OH, Ti I, TiO, V I, V II, VO, and Y I. By employing likelihood mapping, we find indications of there being little variation in emission line contrast between the day- and nightsides $-$suggesting that KELT-9b may harbor iron emission on its nightside. Our results demonstrate that high-resolution ground-based emission spectroscopy can provide valuable insights into exoplanet atmospheres.Comment: Accepted for publication in A

Companions to Kepler giant stars: A long-period eccentric substellar companion to KIC 3526061 and a stellar companion to HD 187878

Context. Our knowledge of populations and occurrence of planets orbiting evolved intermediate-mass stars is still incomplete. In 2010 we started a planet-search program among 95 giant stars observed by the Kepler mission to increase the sample of giant stars with planets and with reliable estimates of stellar masses and radii. Aims. We present the two systems KIC 3526061 and HD 187878 from our planet-search program for which we could characterise their companions. Methods. We used precise stellar radial velocity measurements taken with four different echelle spectrographs to derive an orbital solution. We used Gaia astrometric measurements to obtain the inclination of the HD 187878 system and Kepler photometric observations to estimate the stellar mass and radius. Results. We report the discovery of a sub-stellar and a stellar companion around two intermediate-mass red giant branch stars. KIC 3526061 b is most likely a brown dwarf with a minimum mass of 18.15 Jupiter masses in a long-period eccentric orbit, with the orbital period 3552 d and orbital eccentricity 0.85. It is the most evolved system found having a sub-stellar companion with such a large eccentricity and wide separation. HD 187878 B has a minimum mass of 78.4 Jupiter masses. Combining the spectroscopic orbital parameters with the astrometric proper motion anomaly we derived an orbital inclination 9.8 deg, which corresponds to the companion's mass in the stellar regime of 0.51 Sun mass. Conclusions. A sub-stellar companion of KIC 3526061 extends the sample of known red giant branch stars with sub-stellar companions on very eccentric wide orbits and might provide a probe of the dynamical evolution of such systems over time.Comment: 14 pages, 11 figures. Accepted to A&

Complementary Building Concept: Wooden Apartment Building: The Noppa toward Zero Energy Building Approach

Increasing the construction of wooden apartment buildings has its place as part of preventing climate change. This chapter aims to explore the possibilities of expanding the construction of wooden apartment buildings on plots owned by the City of Helsinki in the Mellunkylä area by developing a series-produced wooden apartment building concept suitable for complementary construction—The Noppa concept. The sustainability of this approach is considered from the perspective of materials, construction methods, adaptability of the designed spaces, and housing design flexibility. In this study, the Noppa wooden apartment building concept with cross-laminated timber (CLT) elements has been developed varying in its facilities and architectural design features through architectural modeling programs to be used for complementary construction. The research findings are based on a theoretical approach that has not yet been practically tested but is proposed considering existing construction practices that need further investigation. It is believed that this chapter will contribute to the spread of wooden apartments to achieve a low-carbon economy as one of the key tools in tackling climate change problems. Particularly, proposed architectural design solutions will contribute to decarbonization of buildings as well as zero energy building (nZEB) approach

The GW Vir instability strip in the light of new observations of PG 1159 stars. Discovery of pulsations in the central star of Abell 72 and variability of RX J0122.9-7521

We present the results of new time series photometric observations of 29 pre-white dwarf stars of PG 1159 spectral type, carried out in the years 2014-2022. For the majority of stars, a median noise level in Fourier amplitude spectra of 0.5-1.0 mmag was achieved. This allowed the detection of pulsations in the central star of planetary nebula Abell 72, consistent with g-modes excited in GW Vir stars, and variability in RX J0122.9-7521 that could be due to pulsations, binarity or rotation. For the remaining stars from the sample that were not observed to vary, we placed upper limits for variability. After combination with literature data, our results place the fraction of pulsating PG 1159 stars within the GW Vir instability strip at 36%. An updated list of all known PG 1159 stars is provided, containing astrometric measurements from the recent Gaia DR3 data, as well as information on physical parameters, variability, and nitrogen content. Those data are used to calculate luminosities for all PG 1159 stars to place the whole sample on the theoretical Hertzsprung-Russell diagram for the first time in that way. The pulsating stars are discussed as a group, and arguments are given that the traditional separation of GW Vir pulsators in "DOV" and "PNNV" stars is misleading and should not be used.Comment: Accepted for publication in ApJ

Cluster Analysis of Finnish Population-Based Adult-Onset Asthma Patients

Background: Phenotypes of adult asthma have been identified in previous studies but rarely in population-based settings. Objective: To identify clusters of adult-onset asthma in a Finnish population-based study on subjects born before 1967. Methods: We used population-based data from 1350 asthmatics with adult-onset asthma (Adult Asthma in Finland) from Finnish national registers. Twenty-eight covariates were selected based on literature. The number of covariates was reduced by using factor analysis before cluster analysis. Results: Five clusters (CLU1-CLU5) were identified, 3 clusters with late-onset adult asthma (onset ≥40 years) and 2 clusters with onset at earlier adulthood (<40 years). Subjects in CLU1 (n = 666) had late-onset asthma and were nonobese, symptomatic, and predominantly female with few respiratory infections during childhood. CLU2 (n = 36) consisted of subjects who had earlier-onset asthma, were predominantly female, obese with allergic asthma, and had recurrent respiratory infections. Subjects in CLU3 (n = 75) were nonobese, older, and predominantly men with late-onset asthma, smoking history, comorbidities, severe asthma, least allergic diseases, low education, many siblings, and childhood in rural areas. CLU4 (n = 218) was a late-onset cluster consisting of obese females with comorbidities, asthma symptoms, and low education level. Subjects in CLU5 (n = 260) had earlier onset asthma, were nonobese, and predominantly allergic females. Conclusions: Our population-based adult-onset asthma clusters take into account several critical factors such as obesity and smoking, and identified clusters that partially overlap with clusters identified in clinical settings. Results give us a more profound understanding of adult-onset asthma phenotypes and support personalized management.publishedVersionPeer reviewe

TOI-2046b, TOI-1181b, and TOI-1516b, three new hot Jupiters from TESS: planets orbiting a young star, a subgiant, and a normal star

We present the confirmation and characterization of three hot Jupiters, TOI-1181b, TOI-1516b, and TOI-2046b, discovered by the TESS space mission. The reported hot Jupiters have orbital periods between 1.4 and 2.05 d. The masses of the three planets are 1.18 ± 0.14 MJ, 3.16 ± 0.12 MJ, and 2.30 ± 0.28 MJ, for TOI-1181b, TOI-1516b, and TOI-2046b, respectively. The stellar host of TOI-1181b is a F9IV star, whereas TOI-1516b and TOI-2046b orbit F main sequence host stars. The ages of the first two systems are in the range of 2–5 Gyrs. However, TOI-2046 is among the few youngest known planetary systems hosting a hot Jupiter, with an age estimate of 100–400 Myrs. The main instruments used for the radial velocity follow-up of these three planets are located at Ondřejov, Tautenburg, and McDonald Observatory, and all three are mounted on 2–3 m aperture telescopes, demonstrating that mid-aperture telescope networks can play a substantial role in the follow-up of gas giants discovered by TESS and in the future by PLATO

Global Biobank Meta-analysis Initiative:Powering genetic discovery across human disease

Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. We introduce the Global Biobank Meta-analysis Initiative (GBMI)—a collaborative network of 23 biobanks from 4 continents representing more than 2.2 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWASs generated using harmonized genotypes and phenotypes from member biobanks for 14 exemplar diseases and endpoints. This strategy validates that GWASs conducted in diverse biobanks can be integrated despite heterogeneity in case definitions, recruitment strategies, and baseline characteristics. This collaborative effort improves GWAS power for diseases, benefits understudied diseases, and improves risk prediction while also enabling the nomination of disease genes and drug candidates by incorporating gene and protein expression data and providing insight into the underlying biology of human diseases and traits.</p

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms