186 research outputs found

    The Effective Personnel Selection Via Multi-criteria Decision-making Method Analytic Hierarchy Process (AHP): A Web-based Application

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    Decision-making is a process that people encounter in their daily or business lives. The process aims at reaching a conclusion depending on the aims of the people. Multiple factors affect the process of decision-making depending on the characteristics of these factors. These factors that affect the process of decision-making complicate encountered problems, and in this stage as a solution, multi-criteria decision-making methods are preferred to use by the decision-makers. Decision-making methods are categorized according to specific goals served to give the best results to decisionmakers. Certainly, the most important goal for organizations is to ensure that the right person works in the right job in line with his/her goals. The problems that are encountered by human resources managers is decision-making problems. A small mistake made by human resource department during the personnel selection can cause negative consequences in short or long term for companies. In this study, a web-based application was developed in order to solve the personnel-selection problems of human resources management. A model that is based on multi-criteria selection has been developed to ensure the elimination of candidates through the program based on solution algorithm of Analytic Hierarchy Process (AHP), which is one of the most widely used decision-making methods designed as a web-based application so far.     Keywords: multi-criteria decision-making, analytic hierarchy process, human resources management, personnel selection, web-based applicatio

    New Physics at the LHC. A Les Houches Report: Physics at TeV Colliders 2009 - New Physics Working Group

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    We present a collection of signatures for physics beyond the standard model that need to be explored at the LHC. First, are presented various tools developed to measure new particle masses in scenarios where all decays include an unobservable particle. Second, various aspects of supersymmetric models are discussed. Third, some signatures of models of strong electroweak symmetry are discussed. In the fourth part, a special attention is devoted to high mass resonances, as the ones appearing in models with warped extra dimensions. Finally, prospects for models with a hidden sector/valley are presented. Our report, which includes brief experimental and theoretical reviews as well as original results, summarizes the activities of the "New Physics" working group for the "Physics at TeV Colliders" workshop (Les Houches, France, 8-26 June, 2009).Comment: 189 page

    Mapping interactions with the chaperone network reveals factors that protect against tau aggregation.

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    A network of molecular chaperones is known to bind proteins ('clients') and balance their folding, function and turnover. However, it is often unclear which chaperones are critical for selective recognition of individual clients. It is also not clear why these key chaperones might fail in protein-aggregation diseases. Here, we utilized human microtubule-associated protein tau (MAPT or tau) as a model client to survey interactions between ~30 purified chaperones and ~20 disease-associated tau variants (~600 combinations). From this large-scale analysis, we identified human DnaJA2 as an unexpected, but potent, inhibitor of tau aggregation. DnaJA2 levels were correlated with tau pathology in human brains, supporting the idea that it is an important regulator of tau homeostasis. Of note, we found that some disease-associated tau variants were relatively immune to interactions with chaperones, suggesting a model in which avoiding physical recognition by chaperone networks may contribute to disease

    New Physics at the LHC. A Les Houches Report: Physics at TeV Colliders 2009 - New Physics Working Group

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    We present a collection of signatures for physics beyond the standard model that need to be explored at the LHC. First, are presented various tools developed to measure new particle masses in scenarios where all decays include an unobservable particle. Second, various aspects of supersymmetric models are discussed. Third, some signatures of models of strong electroweak symmetry are discussed. In the fourth part, a special attention is devoted to high mass resonances, as the ones appearing in models with warped extra dimensions. Finally, prospects for models with a hidden sector/valley are presented. Our report, which includes brief experimental and theoretical reviews as well as original results, summarizes the activities of the "New Physics" working group for the "Physics at TeV Colliders" workshop (Les Houches, France, 8-26 June, 2009)

    Heterogeneously catalyzed lignin depolymerization

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    Biomass offers a unique resource for the sustainable production of bio-derived chemical and fuels as drop-in replacements for the current fossil fuel products. Lignin represents a major component of lignocellulosic biomass, but is particularly recalcitrant for valorization by existing chemical technologies due to its complex cross-linking polymeric network. Here, we highlight a range of catalytic approaches to lignin depolymerisation for the production of aromatic bio-oil and monomeric oxygenates

    Abstracts of presentations on plant protection issues at the fifth international Mango Symposium Abstracts of presentations on plant protection issues at the Xth international congress of Virology: September 1-6, 1996 Dan Panorama Hotel, Tel Aviv, Israel August 11-16, 1996 Binyanei haoma, Jerusalem, Israel

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    Collider aspects of flavour physics at high Q

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    This review presents flavour related issues in the production and decays of heavy states at LHC, both from the experimental side and from the theoretical side. We review top quark physics and discuss flavour aspects of several extensions of the Standard Model, such as supersymmetry, little Higgs model or models with extra dimensions. This includes discovery aspects as well as measurement of several properties of these heavy states. We also present public available computational tools related to this topic.Comment: Report of Working Group 1 of the CERN Workshop ``Flavour in the era of the LHC'', Geneva, Switzerland, November 2005 -- March 200

    HSP90 regulates temperature-dependent seedling growth in Arabidopsis by stabilizing the auxin co-receptor F-box protein TIR1

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    Recent studies have revealed that a mild increase in environmental temperature stimulates the growth of Arabidopsis seedlings by promoting biosynthesis of the plant hormone auxin. However, little is known about the role of other factors in this process. In this report we show that increased temperature promotes rapid accumulation of the TIR1 auxin co-receptor, an effect that is dependent on the molecular chaperone HSP90. In addition, we show that HSP90 and the co-chaperone SGT1 each interact with TIR1, confirming that TIR1 is an HSP90 client. Inhibition of HSP90 activity results in degradation of TIR1 and interestingly, defects in a range of auxin-mediated growth processes at lower as well as higher temperatures. Our results indicate that HSP90 and SGT1 integrate temperature and auxin signaling in order to regulate plant growth in a changing environment

    Periodicities in the Daily Proton Fluxes from 2011 to 2019 Measured by the Alpha Magnetic Spectrometer on the International Space Station from 1 to 100 GV

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    We present the precision measurement of the daily proton fluxes in cosmic rays from May 20, 2011 to October 29, 2019 (a total of 2824 days or 114 Bartels rotations) in the rigidity interval from 1 to 100 GV based on 5.5×109 protons collected with the Alpha Magnetic Spectrometer aboard the International Space Station. The proton fluxes exhibit variations on multiple timescales. From 2014 to 2018, we observed recurrent flux variations with a period of 27 days. Shorter periods of 9 days and 13.5 days are observed in 2016. The strength of all three periodicities changes with time and rigidity. The rigidity dependence of the 27-day periodicity is different from the rigidity dependences of 9-day and 13.5-day periods. Unexpectedly, the strength of 9-day and 13.5-day periodicities increases with increasing rigidities up to ∼10 GV and ∼20 GV, respectively. Then the strength of the periodicities decreases with increasing rigidity up to 100 GV.</p
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