Surface Waves In Homogeneous Visco-Elastic Media Of Higher Order Under The Influence Of Gravity And Surface Stresses

The aim of the present paper is to investigate the surface waves in a homogeneous, isotropic, visco-elastic solid medium of nth order, including time rate of strain under the influence of gravity and surface stresses. The theory of generalized surface waves is developed to investigate particular cases of waves such as the Stoneley, Rayleigh and Love waves. Corresponding equations have been obtained for different cases. These reduced to classical results, when the effects of gravity, surface stresses and viscosity are ignored. Keywords: Gravity, Surface waves, Visco-elasticity, Surface stresses

Development of Marine Ornamental Fishes of Andaman and Nicobar Islands Commercial Scope and Sustainability

The ornamental fish production world-wide has grown to such an extent that it has earned for itself an integrated place of distinction in international fish business. It is estimated that about 1.5 - 2.0 million people worldwide keep marine aquarta and that approximately half of them are in United States alone

Circadian rhythm disruption and Alzheimer’s disease: The dynamics of a vicious cycle

All mammalian cells exhibit circadian rhythm in cellular metabolism and energetics. Autonomous cellular clocks are modulated by various pathways that are essential for robust time keeping. In addition to the canonical transcriptional translational feedback loop, several new pathways of circadian timekeeping - non-transcriptional oscillations, post-translational modifications, epigenetics and cellular signaling in the circadian clock - have been identified. The physiology of circadian rhythm is expansive, and its link to the neurodegeneration is multifactorial. Circadian rhythm disruption is prevelant in contamporary society where light-noise, shift-work, and transmeridian travel are commonplace, and is also reported from the early stages of Alzheimer's disease (AD). Circadian alignment by bright light therapy in conjunction with chronobiotics is beneficial for treating sundowning syndrome and other cognitive symptoms in advanced AD patients. We performed a comprehensive analysis of the clinical and translational reports to review the physiology of the circadian clock, delineate its dysfunction in AD, and unravel the dynamics of the vicious cycle between two pathologies. The review delineates the role of putative targets like clock proteins PER, CLOCK, BMAL1, ROR, and clock-controlled proteins like AVP, SIRT1, FOXO, and PK2 towards future approaches for management of AD. Furthermore, the role of circadian rhythm disruption in aging is delineated

COMPARATIVE ANALYSIS OF RECTANGULAR AND CIRCULAR WAVEGUIDE USING MATLAB SIMULATION

Abstract Electromagnetic waves is very strong waves which is used for transmission of signals from one place to other , main concern is medium having some physical structure through which it can propagate their waves. There are so many ways to guide this electromagnetic waves but main consideration in this paper is rectangular waveguide and circular waveguide.This paper analyze the different parameters of both the waveguides like (Cut off frequency, Cut off wavelength, Guide wavelength,Phase velocity, Group velocity, Impedance, power, Attenuation, VSWR) with the help of simulation in Matlab7.14 .Compare the parameters of the two waveguides and on the basis of these parameters result it is easy to get the best guided structure

Knowledge, awareness and practices regarding dengue fever among the adult population of dengue hit cosmopolitan.

Background: The World health Organization (WHO) declares dengue and dengue hemorrhagic fever to be endemic in South Asia. Despite the magnitude of problem, no documented evidence exists in Pakistan which reveals the awareness and practices of the country\u27s adult population regarding dengue fever, its spread, symptoms, treatment and prevention. This study was conducted to assess the level of knowledge, attitudes and practices regarding dengue fever in people visiting tertiary care hospitals in Karachi, Pakistan. Methods: A cross-sectional pilot study was conducted among people visiting tertiary care hospitals in Karachi. Through convenience sampling, a pre-tested and structured questionnaire was administered through a face-to-face unprompted interview with 447 visitors. Knowledge was recorded on a scale of 1-3. Results: About 89.9% of individuals interviewed had heard of dengue fever. Sufficient knowledge about dengue was found to be in 38.5% of the sample, with 66% of these in Aga Khan University Hospital and 33% in Civil Hospital Karachi. Literate individuals were relatively more well-informed about dengue fever as compared to the illiterate people (p\u3c0.001). Knowledge based upon preventive measures was found to be predominantly focused towards prevention of mosquito bites (78.3%) rather than eradication of mosquito population (17.3%). Use of anti-mosquito spray was the most prevalent (48.1%) preventive measure. Television was considered as the most important and useful source of information on the disease.Conclusion: Adult population of Karachi has adequate knowledge related to the disease \u27dengue\u27 on isolated aspects, but the overall prevalence of \u27sufficient knowledge\u27 based on our criteria is poor. We demonstrated adequate prevalence of preventive practices against the disease. Further studies correlating the association between knowledge and its effectiveness against dengue will be helpful in demonstrating the implications of awareness campaigns

Power augmentation and Ramp-Up rate improvement through compressed air Injection: a dry low NOx combustor CFD analysis

Gas turbines play a key role in accelerating the transition towards more environmentally friendly power generation. This role includes backup of renewable generation that is intermittent, providing grid inertia as well as other ancillary services for grid stability. For quick backup power, the ramp-up rate of gas turbines can be improved through air injection at the back of the compressor, facilitated by integrating compressed air energy storage. Published works have mostly focused on low-fidelity engine system analysis of air injection overall effects. No study has focused on the detailed combustor performance presented in this study. The work shows the impact of air injection on the emissions, thermoacoustic stability and liner wall durability. These yardsticks in assessing the operability of the combustor have also been used for air power augmentation and ramp-up analysis. ANSYS software was used in the computational fluid dynamics (CFD) analysis of the three-dimensional dry low NOx combustor. Low-order models were used for the thermoacoustic stability and durability analysis. For the power augmentation study, the NO and CO emissions produced at 15 % air injection are below the maximum values of the combustor in design operations. Also, the stability and durability were within limits. The ramp-up investigation indicates up to 10 % air injection is allowed and the emissions are similarly acceptable. However, the thermoacoustic analysis shows a potential for combustion instabilities at high frequencies above 1800 Hz. Generally, there was no unusual wall liner durability in these two studies. When benchmarked against previous engine-level analysis, the ramp-up rate can be potentially improved by 54 % if the small concern on thermoacoustic instability is resolved

Chronic Hepatitis C

The goal of antiviral therapy for patients with chronic hepatitis C virus (HCV) infection is to attain a sustained virologic response (SVR), which is defined as undetectable serum HCV-RNA levels at 6 months after the cessation of treatment. Major improvements in antiviral therapy for chronic hepatitis C have occurred in the past decade. The addition of ribavirin to interferon-alfa therapy and the introduction of pegylated interferon (PEG-IFN) have substantially improved SVR rates in patients with chronic hepatitis C. The optimization of HCV therapy with PEG-IFN and ribavirin continues to evolve. Studies are ongoing that use viral kinetics to tailor therapy to an individual's antiviral response and determine the ideal length of treatment to maximize the chance of SVR. Improved SVR can be achieved with new specific inhibitors that target the HCV NS3/4A protease and the NS5B polymerase. Several long-term follow-up studies have shown that SVR, when achieved, is associated with a very low risk of virologic relapse. Furthermore, antiviral therapy can reduce the morbidity and mortality rates associated with chronic hepatitis C by reducing fibrosis progression, the incidence of cirrhosis, and hepatocellular carcinoma

Reconceptualization of information technology flexibility for supply chain management: an empirical study

IT flexibility is an increasingly important factor in today's dynamic business environment. However, earlier research lacks 1) an integrated framework that corresponds to diverse processes for supply chain management and 2) an explanation of how IT flexibility affects firms’ performance in the supply chain context. To fill these gaps, our study theorised a research model by integrating disparate streams of IT flexibility research with three types of IT flexibility, namely, operational, transactional, and strategic, and tested both the direct and indirect effects of the three IT flexibility types on firm performance. Our theoretical model uses an extended resource-based view to highlight the role of IT flexibility in managing interdependent firm relationships in supply chains. Using a partial least squares approach to structured equation modelling analysis on 162 questionnaires from supply chain practitioners, we found two significant relationships: (1) transactional IT flexibility affects operational IT flexibility, and (2) operational IT flexibility affects strategic IT flexibility. Transactional IT flexibility also affects strategic IT flexibility, thus playing a pivotal role in the effectiveness of the other two flexibility types. In addition, it was identified that transactional and operational flexibilities affect firm performance indirectly, via process integration capability, while strategic flexibility directly affects firm performance. By classifying diverse IT flexibility attributes into three types, a comprehensive and explicit concept of IT flexibility in inter-organisational relationships is attained, which allows practitioners to target key resource investments to realise the full potential of IT in the supply chain