Pure double-layer bubbles in quadratic F ( R ) gravity

We present a class of spherically symmetric spacetimes corresponding tobubbles separating two regions with constant values of the scalar curvature, orequivalently with two different cosmological constants, in quadratic F(R)theory. The bubbles are obtained by means of the junction formalism, and thematching hypersurface supports in general a thin shell and a gravitationaldouble layer. In particular, we find that pure double layers are possible forappropriate values of the parameters of the model whenever the quadraticcoefficient is negative. This is the first example of a pure double layer in agravitational theory.Fil: Eiroa, Ernesto Fabian. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Figueroa Aguirre, Griselda Verónica. Consejo Nacional de Investigaciónes Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Astronomía y Física del Espacio. - Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Astronomía y Física del Espacio; ArgentinaFil: Senovilla, José M. M.. Universidad del País Vasco; Españ

An enigmatic kilometer-scale concentration of small mytilids (Late Miocene, Guadalquivir Basin, S Spain).

Upper Miocene heterozoan carbonates crop out extensively in a NE-SW-trending belt (42 km long and 1.5-8 km wide) along the so-called El Alcor topographic high, from Carmona to Dos Hermanas (Seville, S Spain). These carbonates formed at the southern active margin of the Guadalquivir Basin, the foreland basin of the Betic Cordillera. They change to marls basinward (NE) and to sands landward (SE and SW). Therefore, carbonate production was constrained to a limited area in an otherwise siliciclastic shelf. The carbonates (up to 40 m thick) overlie a gradually coarsening-upward succession of marls followed by silts and sandstones. The carbonate sequence can be divided into three subunits corresponding, frombottom to top, to lowstand, transgressive, and highstand system tract deposits. The lower subunit, exhibiting extensive trough cross-bedding, is interpreted as a shallow-water bar deposit. The intermediate subunit onlaps underlying sediments and was deposited in deeper, lowturbulence conditions. The upper subunit deposits accumulated in a well-oxygenated outer platform based on benthic foraminiferal assemblages. The presence of hummocky and swaley cross-stratification in these latter deposits suggests that theywere affected by storms. Pervasive fluid-escape structures are also observed throughout the carbonates. The three subunits consist of bioclastic packstones to rudstonesmade up of abundant fragments of smallmytilids. Isotopic data from serpulid polychaete Ditrupa tubes show 13C-depleted values (up to −16.1¿), whereas δ18O yields normal marine values. Additional isotopic data on shells of scallops, oysters, and small mussels, as well as bulk sediment, show diagenetic alterations. Based on actualistic examples of massive concentrations of mussels, the nearly monospecific composition of the El Alcor deposits, together with negative δ13C values of Ditrupa tubes, indicates that cold seeps presumably promoted carbonate formation. However, the absence of typical features of cold-seep deposits, such as authigenic carbonatesmediated by anaerobic bacterial activity and the typical chemosynthetic shelly organisms, makes the large carbonate body of El Alcor an unusual cold-seep deposit

Representación virtual interactiva del desaparecido convento del Carmen (Logroño) generada a partir de una maqueta de papel

[EN] The concept of mock-up, which share with the drawing the expressive synthesis for the analysis of the architectural form and evolution, is an invaluable asset for the preservation of the heritage. To mark the 175th anniversary of the Práxedes Mateo Sagasta’s secondary school of Logroño (Spain), an exhibition about the history of the institution was organized at the premises of La Rioja Library. The current school building became operational in 1900 and was built on the former site of a Carmelite convent. In fact, the convent rooms were the first location for the school, after the expropriations of religious communities during the mid-19th century. For the benefit of the aforementioned exhibition, it was considered interesting to generate a three-dimensional (3D) virtual reconstruction of the convent buildings to show how it would have looked. However, the lack of sufficient contemporary graphic information was a challenge, so it was decided that an efficient solution would be to generate the virtual reconstruction from a paper craft model, which had been created by the librarian of the secondary school as a result of his research on this matter. This text describes the 3D modelling of that cut-out element by means of monoscopic photogrammetry (perspective drawing) and the use of non-realistic rendering based on the appearance of the paper mock-up (and not trying to recreate the real image of the buildings) so as to provide a suggestive view of the convent and create interactive exhibition items. Moreover, the text deals with the long-term preservation and the improvement of the re-use of the 3D models. The former by resorting to institutional repositories —from which users can download the full detailed versions— and the latter employing versions able to be visualized in 3D warehouses (such as Sketchfab) and augmented reality (AR) applications.Highlights:A significant part of the architectural heritage is represented by mock-ups of different materials (paper, wood, metal and so on).Virtual modelling and augmented reality (AR) can be appropriate tools for materializing, recovering and disseminating scale models to the public.Techniques for geometric documentation and visual representation need to be adapted in order to tackle the peculiar features of these elements (size, materials, fragility, etc.).[ES] La maqueta, que comparte con el dibujo la síntesis expresiva para el análisis de la forma y evolución arquitectónica, resulta de un valor incalculable para la preservación del patrimonio. Con motivo del 175 aniversario del Instituto de Enseñanza Secundaria Práxedes Mateo Sagasta de Logroño (España) se organizó una exposición sobre su historia en la Biblioteca de La Rioja. El edificio que actualmente acoge el instituto fue inaugurado en el año 1900 y se construyó sobre el mismo terreno en el que, previamente, había estado un convento de Carmelitas. De hecho, la primera sede del instituto estuvo situada en las dependencias de este mismo convento, tras la desamortización de los edificios eclesiásticos que tuvo lugar a mediados del siglo XIX. Como parte de la muestra, se consideró interesante generar una reconstrucción virtual tridimensional (3D) de los edificios del convento con el fin de mostrar cómo debieron haber sido. La dificultad, sin embargo, residía en la escasez de fuentes gráficas de la época que permitieran conocer su forma y apariencia; por este motivo, se decidió utilizar como base para la recreación virtual una maqueta en papel que había sido realizada por el bibliotecario del instituto como resultado de sus investigaciones a lo largo de los años. El presente texto describe el proceso de modelado 3D a partir de esta maqueta de papel utilizando técnicas de fotogrametría monoscópica (dibujo perspectivo) y el empleo de renderizados no realistas basados en el aspecto de la maqueta de papel (y no en el que debieron tener los edificios) con el fin de generar vistas evocadoras del convento y crear contenidos útiles para la mencionada exposición. Asimismo, el texto trata la preservación a largo plazo de los modelos 3D y el incremento de su reutilización. En el primer caso, mediante el empleo de los repositorios institucionales —desde donde los usuarios pueden descargarse las versiones más detalladas— y, para el segundo fin, mediante la creación de versiones para su uso a través de almacenes de modelos 3D (como Sketchfab) y aplicaciones de realidad aumentada (RA).The authors wish to thank Mr. Alberto Abad Benito, director of the Práxedes Mateo Sagasta’s secondary school, for his enthusiasm and help in the development of this project. This article is dedicated to the memory of Mr. Fernando R. Blanco Martín, librarian of the Práxedes Mateo Sagasta’s secondary school for more than 25 years, who sadly died in 2019. We are grateful for both his tireless work in recovering information concerning the history of the city and the school, as well as the many pleasant conversations with him enjoyed by these authors. The participation of Jaione Korro in this research is supported by the Basque Government through a grant for doctoral studies of the call 2019-2020.Rodríguez-Miranda, A.; Valle Melón, JM.; Korro Bañuelos, J.; Elorriaga Aguirre, G. (2021). Interactive virtual representation of the disappeared convent of El Carmen (Logroño) generated from a paper craft model. Virtual Archaeology Review. 12(24):77-89. https://doi.org/10.4995/var.2021.14038OJS77891224Apollonio F. I. (2016). Classification schemes for visualization of uncertainty in digital hypothetical reconstructions. In S. Münster,M. Pfarr-Harfst, P. Kuroczyński & M. Ioannides (Eds.), 3D Research challenges in cultural heritage II. Lecture Notes in Computer Science, 10025, 173-197. Cham: Springer. http://dx.doi.org/10.1007/978-3-319-47647-6_9Azara, P., & Esparza, V. (2006). Maquetas en el mundo antiguo: entrevista a Pedro Azara. DC. Revista de crítica arquitectónica, 15-16, 55-62.Buriánek, J. (2011). Digital Langweil model of Prague. 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Virtualizing ancient Rome: 3D acquisition and modeling of a large plaster-of-Paris model of imperial Rome. Electronic imaging, 5665, 119-133.Herrero, J. (2014). Modelos y maquetas en la historia. In M. H. Herránez Martín (Coord.), Modelos y maquetas: la vida a escala. Madrid: Ministerio de Educación, Cultura y Deporte (Spain), 7-24.Hervy, B., Billen, R., Laroche, F., Carré, C., Servieres, M., … & Kerouanton, J. (2012). A generalized approach for historical mock-up acquisition and data modelling: towards historically enriched 3D city models. Usage, Usability, and Utility of 3D City Models, 02009. https://doi.org/10.1051/3u3d/201202009Kersten, T. P., Keller, F., Saenger, J., & Schiewe, J. (2012). Automated Generation of an Historic 4D City Model of Hamburg and Its Visualisation with the GE Engine. In EuroMed 2012. Lecture Notes in Computer Science, 7616, 55-65. Berlin, Heidelberg: Springer. https://doi.org/10.1007/978-3-642-34234-9_6Lecocq, F. (2004). Reconstitution virtuelle de Rome Antique. In R. Vergnieux & C. Delevoie (Eds.), Actes du Colloque Virtual Retrospect 2003. Archéovision, 1, 77-84.Lengyel, D., & Toulouse, C. (2016). Visualization of uncertainty in archaeological reconstructions. In S. Hoppe & S. Breitling (Eds.), Virtual Palaces, Part II. Lost Palaces and their Afterlife (pp. 103-117). Heidelberg: arthistoricum.net. https://doi.org/10.11588/arthistoricum.83.79Maiwald, F., Bruschke, J., Lehmann, C., & Niebling, F. (2019). A 4D information system for the exploration of multitemporal images and maps using photogrammetry, web technologies and VR/AR. Virtual Archaeology Review, 10(21), 1-13. https://doi.org/10.4995/var.2019.11867Moreno, M. (2014). Modelos y maquetas en el Museo Tiflológico. In M. H. Herránez Martín (Coord.), Modelos y maquetas: la vida a escala (pp. 205-211). Madrid: Ministerio de Educación, Cultura y Deporte (Spain).Noardo, F. (2018). Architectural heritage semantic 3D documentation in multi-scale standard maps. Journal of Cultural Heritage, 32, 156-165. https://doi.org/10.1016/j.culher.2018.02.009Quirós, F. (1994). Las colecciones militares de modelos de ciudades españolas, y el Real Gabinete Topográfico de Fernando VII. Una aproximación. Ería, 35, 203-224.Rizvic, S., Pletinckx, D., & Okanović, V. (2015). Enhancing museum exhibitions with interactive digital content. Sarajevo City Model Interactive. In XXV International Conference on Information, Communication and Automation Technologies (ICAT), Sarajevo, Bosnia and Herzegovina. https://doi.org/10.1109/ICAT.2015.7340510Rodríguez Hidalgo, J. M. (2010). De la reconstrucción tradicional a la virtual. Una visión desde la arqueología. Virtual Archaeology Review, 1(1), 163-167. https://doi.org/10.4995/var.2010.5140Rodríguez Miranda, Á., Korro Bañuelos, J., & Valle Melón, J. M. (2020). Archivo y difusión de contenidos 3D de elementos patrimoniales en repositorios institucionales y plataformas comerciales. Revista PH, 100, 78-80. https://doi.org/10.33349/2020.100.4641Rodríguez Miranda, Á., & Valle Melón, J. M. (2017). Recovering old stereoscopic negatives and producing digital 3D models of former appearances of historic buildings. The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, XLII-2/W3, 601-608. https://doi.org/10.5194/isprs-archives-XLII-2-W3-601-2017Rodríguez Miranda, Á., Valle Melón, J. M., & Lopetegi Galarraga, A. (2007). Ajuste radiométrico de texturas fotográficas en modelos virtuales y nubes de puntos de elementos patrimoniales. In 7ª Semana Geomática. Barcelona, Spain.Scopigno, R., Callieri, M., Dellepiane, M., Ponchio, F., & Potenziani, M. (2017). Delivering and using 3D models on the web: Are we ready?. 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Microparticle movements in optical funnels and pods

Three-dimensional microparticle movements induced by laser beams with a funnel-and tubular pod-like structure, in the neighbourhood of the focal plane of an optical trapping setup, are experimentally studied. The funnel and pod beams constructed as coherent superpositions of helical Laguerre-Gaussian modes are synthesized by a computer generated hologram using a phase-only spatial light modulator. Particle tracking is achieved by in-line holography method which allows an accurate position measurement. It is experimentally demonstrated that the trapped particle follows different trajectories depending on the orbital angular momentum density of the beam. In particular applying the proposed pod beam the particle rotates in opposite directions during its movement in the optical trap. Possible applications of these single-beam traps for volumetric optical particle manipulation are discussed. © 2011 Optical Society of America.The financial support of the Spanish Ministry of Science and Innovation under projects TEC2008-04105, TEC2009-5545-E/TEC are acknowledged. J. A. Rodrigo and A. M. Caravaca-Aguirre gratefully thank a “Juan de la Cierva” grant and fellowship from “Obra Social Ibercaja (Beca Ibercaja de Investigación 2010)”, respectively. The authors appreciate valuable comments from J. R. Arias-González.Peer Reviewe

A Combined Bi-objective Optimization and Bayesian Framework to Postulate Pharmacometric Compartmental Models

Recently, some applications of Process Systems Engineering to physiology and clinical medicine make use of compartmental analysis to represent transport of material in biological processes. One of the first steps of this analysis is to generate a set of plausible models that describe the system under study. In a previous work, we have proposed an optimization framework to support this task using a superstructure approach which inherently considers the different feasible flows between any pair of compartments. In this work, we extend such a framework to a bi-objective optimization that allows evaluating the trade-off between model fitness and complexity. To discriminate among the different models in the Pareto frontier, we employ a Bayesian metric which is approximated using a Markov Chain Monte Carlo sampling. We present a case study related to an immuno-oncology agent pharmacokinetics to demonstrate the advantages and limitations of the proposed approach

BODE-Index vs HADO-Score in Chronic Obstructive Pulmonary Disease: Which one to use in general practice?

<p>Abstract</p> <p>Background</p> <p>Forced expiratory volume in one second (FEV₁) is used to diagnose and establish a prognosis in chronic obstructive pulmonary disease (COPD). Using multi-dimensional scores improves this predictive capacity.Two instruments, the BODE-index (<b>B</b>ody mass index, <b>O</b>bstruction, <b>D</b>yspnea, <b>E</b>xercise capacity) and the HADO-score (<b>H</b>ealth, <b>A</b>ctivity, <b>D</b>yspnea, <b>O</b>bstruction), were compared in the prediction of mortality among COPD patients.</p> <p>Methods</p> <p>This is a prospective longitudinal study. During one year (2003 to 2004), 543 consecutively COPD patients were recruited in five outpatient clinics and followed for three years. The endpoints were all-causes and respiratory mortality.</p> <p>Results</p> <p>In the multivariate analysis of patients with FEV₁< 50%, no significant differences were observed in all-cause or respiratory mortality across HADO categories, while significant differences were observed between patients with a lower BODE (less severe disease) and those with a higher BODE (greater severity). Among patients with FEV₁≥ 50%, statistically significant differences were observed across HADO categories for all-cause and respiratory mortality, while differences were observed across BODE categories only in all-cause mortality.</p> <p>Conclusions</p> <p>HADO-score and BODE-index were good predictors of all-cause and respiratory mortality in the entire cohort. In patients with severe COPD (FEV₁< 50%) the BODE index was a better predictor of mortality whereas in patients with mild or moderate COPD (FEV₁≥ 50%), the HADO-score was as good a predictor of respiratory mortality as the BODE-index. These differences suggest that the HADO-score and BODE-index could be used for different patient populations and at different healthcare levels, but can be used complementarily.</p

La cerámica de estilo Cogotas I y los ciclos culturales en las postrimerías de la Edad del Bronce en Navarra

En el presente artículo se analizan los yacimientos conocidos en Navarra con cerámica decorada de estilo Cogotas I, situándolos en su contexto cronológico y cultural. Se analiza la división del territorio en dos grupos con importantes diferencias culturales

Revisión documental de los trabajos de grado de la Especialización en Salud Ocupacional de la Universidad Libre- Seccional Cali, 1997-2011

The specialty in occupational health at Universidad Libre- Seccional Cali was officially started in 1997. Since then, the postgraduate program has been strengthening intellectual production. Objective: Characterize the academic production of students during the past 14 years. Methodology: Descriptive, documentary, and retrospective study. A total of 118 degree dissertations were reviewed by collecting the following information: authors, geographical area, economic sector, type of study, line of research, population, measuring instrument, and bibliographical sources. Results: Most of the dissertations (44.1%) were carried out in companies of the city of Cali. The 89.8% were descriptive and a large proportion was made in the industrial sector (36.4%). The most productive research line was promotion of healthy environments and prevention of occupational risks (22.9%). Most of the studies were conducted on populations of operative workers (49.2%). Conclusions: In recent years, the graduate program has significantly strengthened intellectual production, but it is necessary to strengthen some research lines.La especialización en salud ocupacional de la Universidad Libre-Seccional Cali fue creada desde el año 1997. Durante esto años se ha venido fortaleciendo la producción intelectual. Objetivo: de este trabajo es caracterizar la producción académica de los estudiantes durante los últimos 14 años. Metodología: Estudio descriptivo, documental, retrospectivo, donde se revisaron 118 trabajos de grado, recolectando los siguientes datos: autores, sector geográfico, sector económico, tipo de estudio, línea de investigación, población, instrumento de medición y fuentes bibliográficas. Resultados: La mayoría de los trabajos de grado (44.1%) fueron realizados en empresas de la ciudad de Cali. El 89.8% fueron trabajos de tipo descriptivo y una gran proporción realizados en el sector industrial (36.4%). La línea de investigación de mayor producción es la promoción de entornos saludables y prevención de riesgos laborales (22,9%). En su mayoría, los estudios fueron realizados sobre poblaciones de operarios (49.2%). Conclusiones: Durante los últimos años el programa de postgrado ha fortalecido significativamente la producción intelectual; sin embargo es necesario fortalecer algunas líneas de investigación

Uso de Minería de Datos Para la Determinación de Perfiles Socioeconómicos y Sanitarios en la UNCAus

El proyecto PI N° 91, aprobado por Res. N° 332/18 CS, se desarrolla con el fin de obtener información relevante que detecte variables relacionadas con los frecuentes problemas de salud en la ciudad de Presidencia Roque Sáenz Peña (Chaco, Argentina) y su área de influencia, relacionando los pacientes con su hábitat, ecología y salud. Para ello se trabaja con la información proveniente de las actividades curriculares de vinculación comunitaria que la carrera de Medicina de la UNCAus (Universidad Nacional del Chaco Austral) realiza en los distintos barrios de dicha ciudad y su zona de influencia; con dicha información se construye un almacén de datos (data warehouse) que es estudiado con técnicas de minería de datos (data mining), especialmente técnicas de agrupamiento (clusterización) y de árboles de decisión, a los efectos de conseguir los perfiles característicos relacionados con los distintos tipos de diagnósticos; en un principio se buscan modelos descriptivos de minería de datos, para pasar en el futuro a modelos predictivos, lo cual permitiría disponer de conocimiento que permitiría mejorar la toma de decisiones en cuanto a campañas de salud hacia la población de los barrios de la ciudad de P. R. Sáenz Peña. Project PI N ° 91, approved by Res. N ° 332/18 CS, was developed in order to obtain relevant information that detects variables related to frequent health problems in the city of Presidencia Roque Sáenz Peña (Chaco, Argentina) and its area of influence, relating patients to their habitat, ecology, and health. For this, we work with the information coming from the curricular activities based on the relationship with the community that the Medicine undergraduate degree program of the UNCAus (National University of Chaco Austral) carries out in the different neighborhoods of the said city and its area of influence. With this information, a data warehouse was built and studied with data mining techniques, especially clustering techniques and decision trees, in order to achieve the characteristic profiles related to the different types of diagnosis. Initially, descriptive data mining models was sought and moved on to predictive models in the future. This would result to knowledge that would lead to better decision-making regarding health campaigns towards the population of the neighborhoods of the city of P.R. Sáenz Peña