725 research outputs found
The Influence of Operational Resources and Activities on Indirect Personnel Costs: A Multilevel Modeling Approach
Indirect activities often represent an underemphasized, yet significant, contributing source of costs for organizations. In order to manage indirect costs, organizations must understand how these costs behave relative to changes in operational resources and activities. This is of particular interest to the Air Force and its sister services, because recent and projected reductions in defense spending are forcing reductions in their operational variables, and insufficient research exists to help them understand how this may influence indirect costs. Furthermore, although academic research on indirect costs has advanced the knowledge behind the modeling and behavior of indirect costs, significant gaps in the literature remain. Our research provides important and timely advances to the indirect cost literature. First, our research disaggregates the indirect cost pool and focuses on indirect personnel costs, which represent 33% of all Air Force indirect costs and are a leading source of indirect costs in many organizations. Second, we employ a multilevel modeling approach to capture the hierarchical nature of an enterprise, allowing us to assess the influence that each level of an organization has on indirect cost behavior and relationships. Third, we identify the operational variables that influence indirect personnel costs in the Air Force enterprise, providing Air Force decision-makers with evidence-based knowledge to inform decisions regarding budget reduction strategies
Sexual Dimorphism in Hematocrit Response Following Red Blood Cell Transfusion of Critically Ill Surgical Patients
The change in hematocrit (ΔHct) following packed red blood cell (pRBCs) transfusion is a clinically relevant measurement of transfusion efficacy that is influenced by post-transfusion hemolysis. Sexual dimorphism has been observed in critical illness and may be related to gender-specific differences in immune response. We investigated the relationship between both donor and recipient gender and ΔHct in an analysis of all pRBCs transfusions in our surgical intensive care unit (2006–2009). The relationship between both donor and recipient gender and ΔHct (% points) was assessed using both univariate and multivariable analysis. A total of 575 units of pRBCs were given to 342 patients; 289 (49.9%) donors were male. By univariate analysis, ΔHct was significantly greater for female as compared to male recipients (3.81% versus 2.82%, resp., P < 0.01). No association was observed between donor gender and ΔHct, which was 3.02% following receipt of female blood versus 3.23% following receipt of male blood (P = 0.21). By multivariable analysis, recipient gender remained associated significantly with ΔHct (P < 0.01). In conclusion, recipient gender is independently associated with ΔHct following pRBCs transfusion. This association does not appear related to either demographic or anthropomorphic factors, raising the possibility of gender-related differences in recipient immune response to transfusion
Full-Shell X-Ray Optics Development at NASA Marshall Space Flight Center
NASAs Marshall Space Flight Center (MSFC) maintains an active research program toward the development of high-resolution, lightweight, grazing-incidence x-ray optics to serve the needs of future x-ray astronomy missions such as Lynx. MSFC development efforts include both direct fabrication (diamond turning and deterministic computer-controlled polishing) of mirror shells and replication of mirror shells (from figured, polished mandrels). Both techniques produce full-circumference monolithic (primary + secondary) shells that share the advantages of inherent stability, ease of assembly, and low production cost. However, to achieve high-angular resolution, MSFC is exploring significant technology advances needed to control sources of figure error including fabrication- and coating-induced stresses and mounting-induced distortions
Reconstructing phonon mean free path contributions to thermal conductivity using nanoscale membranes
Knowledge of the mean free path distribution of heat-carrying phonons is key
to understanding phonon-mediated thermal transport. We demonstrate that thermal
conductivity measurements of thin membranes spanning a wide thickness range can
be used to characterize how bulk thermal conductivity is distributed over
phonon mean free paths. A non-contact transient thermal grating technique was
used to measure the thermal conductivity of suspended Si membranes ranging from
15 to 1500 nm in thickness. A decrease in the thermal conductivity from 74% to
13% of the bulk value is observed over this thickness range, which is
attributed to diffuse phonon boundary scattering. Due to the well-defined
relation between the membrane thickness and phonon mean free path suppression,
combined with the range and accuracy of the measurements, we can reconstruct
the bulk thermal conductivity accumulation vs. phonon mean free path, and
compare with theoretical models
First Kepler results on compact pulsators VIII: Mode identifications via period spacings in mode pulsating Subdwarf B stars
We investigate the possibility of nearly-equally spaced periods in 13 hot
subdwarf B (sdB) stars observed with the Kepler spacecraft and one observed
with CoRoT. Asymptotic limits for gravity (g-)mode pulsations provide
relationships between equal period spacings of modes with differing degrees and
relationships between periods of the same radial order but differing degrees.
Period transforms, Kolmogorov-Smirnov tests, and linear least-squares fits have
been used to detect and determine the significance of equal period spacings. We
have also used Monte Carlo simulations to estimate the likelihood that the
detected spacings could be produced randomly.
Period transforms for nine of the Kepler stars indicate ell=1 period
spacings, with five also showing peaks for ell=2 modes. 12 stars indicate ell=1
modes using the Kolmogorov-Smirnov test while another shows solely ell=2 modes.
Monte Carlo results indicate that equal period spacings are significant in 10
stars above 99% confidence and 13 of the 14 are above 94% confidence. For 12
stars, the various methods find consistent regular period spacing values to
within the errors, two others show some inconsistencies, likely caused by
binarity, and the last has significant detections but the mode assignment
disagrees between methods.
We find a common ell=1 period spacing spanning a range from 231 to 272 s
allowing us to correlate pulsation modes with 222 periodicities and that the
ell=2 period spacings are related to the ell=1 spacings by the asymptotic
relationship . We briefly discuss the impact of equal period
spacings which indicate low-degree modes with a lack of significant mode
trappings.Comment: 27 pages, 4 figures, 17 tables. Accepted for publication in Monthly
Notices of the Royal Astronomical Societ
Birthing practices of traditional birth attendants in South Asia in the context of training programmes
Traditional Birth Attendants (TBA) training has been an important component of public health policy interventions to improve maternal and child health in developing countries since the 1970s. More recently, since the 1990s, the TBA training strategy has been increasingly seen as irrelevant, ineffective or, on the whole, a failure due to evidence that the maternal mortality rate (MMR) in developing countries had not reduced. Although, worldwide data show that, by choice or out of necessity, 47 percent of births in the developing world are assisted by TBAs and/or family members, funding for TBA training has been reduced and moved to providing skilled birth attendants for all births. Any shift in policy needs to be supported by appropriate evidence on TBA roles in providing maternal and infant health care service and effectiveness of the training programmes. This article reviews literature on the characteristics and role of TBAs in South Asia with an emphasis on India. The aim was to assess the contribution of TBAs in providing maternal and infant health care service at different stages of pregnancy and after-delivery and birthing practices adopted in home births. The review of role revealed that apart from TBAs, there are various other people in the community also involved in making decisions about the welfare and health of the birthing mother and new born baby. However, TBAs have changing, localised but nonetheless significant roles in delivery, postnatal and infant care in India. Certain traditional birthing practices such as bathing babies immediately after birth, not weighing babies after birth and not feeding with colostrum are adopted in home births as well as health institutions in India. There is therefore a thin precarious balance between the application of biomedical and traditional knowledge. Customary rituals and perceptions essentially affect practices in home and institutional births and hence training of TBAs need to be implemented in conjunction with community awareness programmes
Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918
The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day. Despite this disease burden, the evolutionary history of the A/H1N1 virus is not well understood, particularly whether there is a virological basis for several notable epidemics of unusual severity in the 1940s and 1950s. Using a data set of 71 representative complete genome sequences sampled between 1918 and 2006, we show that segmental reassortment has played an important role in the genomic evolution of A/H1N1 since 1918. Specifically, we demonstrate that an A/H1N1 isolate from the 1947 epidemic acquired novel PB2 and HA genes through intra-subtype reassortment, which may explain the abrupt antigenic evolution of this virus. Similarly, the 1951 influenza epidemic may also have been associated with reassortant A/H1N1 viruses. Intra-subtype reassortment therefore appears to be a more important process in the evolution and epidemiology of H1N1 influenza A virus than previously realized
The Evolution of Bat Vestibular Systems in the Face of Potential Antagonistic Selection Pressures for Flight and Echolocation
PMCID: PMC3634842This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Stellar archaeology: the evolving spectrum of FG Sge
Over an interval of 120 years, the extraordinary object FG Sge has been
transformed from a hot post-AGB star to a very luminous cool supergiant.
Theoretically, this evolution has been associated with the reignition of a
helium-shell during the post-AGB stage. A series of studies of the chemical
composition of the photosphere have suggested that this evolution has been
associated with a dramatic increase of approximately 3 dex in the abundances of
s-process elements between about 1960 and 1995. The problem with this apparent
change is that it occurred at a time when the surface convection zone, which is
governed by the star's effective temperature, could not have developed
sufficiently to dredge processed material from the stellar interior to the
surface. We have reviewed the chemical evolution of FG Sge by means of
modelling the time-varying spectrum under a range of assumptions. By comparing
these models with published observational data, a self-consistent picture has
emerged. In particular we find that surface hydrogen has been depleted during
the interval in question. In contrast, the s-process abundances have generally
maintained a steady enhancement of around 1 - 2 dex, although some modest
changes may have occurred since 1950. This implies that FG Sge has not just
completed dredging up freshly-produced s-process isotopes. However, there
remains a contradiction between the observed hydrogen-depletion, the age of the
associated planetary nebula, and current evolutionary models for a pre-white
dwarf suffering a late thermal pulse.Comment: 18 pages, 13 figures, A&A in pres
The Kinematic Properties of BHB and RR Lyrae stars towards the Anticentre and the North Galactic Pole: The Transition between the Inner and the Outer Halo
We identify 51 blue horizontal branch (BHB) stars, 12 possible BHB stars and
58 RR Lyrae stars in Anticentre fields. Their selection does not depend on
their kinematics. Light curves and ephemerides are given for 7 previously
unknown RR Lyrae stars. All but 4 of the RR Lyrae stars are of Oosterhoff type
I. Our selection criteria for BHB stars give results that agree with those used
by Smith et al. (2010) and Ruhland et al. (2011). We use 5 methods to determine
distances for the BHB stars and 3 methods for the RR Lyrae stars to get
distances on a uniform scale. Absolute proper motions (largely derived from the
GSCII and SDSS (DR7) databases) are given for these stars; radial velocities
are given for 31 of the BHB stars and 37 of the RR Lyrae stars. Combining these
data for BHB and RR Lyrae stars with those previously found in fields at the
North Galactic Pole, we find that retrograde orbits dominate for galactocentric
distances greater than 12.5 kpc. The majority of metal-poor stars in the solar
neighbourhood are known to be concentrated in a Lperp vs. Lz angular momentum
plot. We show that the ratio of the number of outliers to the number in the
main concentration increases with galactocentric distance. The location of
these outliers with Lperp and Lz shows that the halo BHB and RR Lyrae stars
have more retrograde orbits and a more spherical distribution with increasing
galactocentric distance. Six RR Lyrae stars are identified in the H99 group of
outliers; the small spread in their [Fe/H] suggests that they could have come
from a single globular cluster. Another group of outliers contains two pairs of
RR Lyrae stars; the stars in each pair have similar properties.Comment: 40 pages, 19 figures, to be published in MNRA
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