4,598 research outputs found
Current considerations for clinical management and care of non-alcoholic fatty liver disease: Insights from the 1st International Workshop of the Canadian NASH Network (CanNASH).
- Author
- Anstee Quentin M
- Bajaj Harpreet
- Berzigotti Annalisa
- Brunt Elizabeth M
- Chevalier StĂŠphanie
- Cobbold Jeremy F
- Ekoe Jean-Marie
- Feld Jordan J
- Ghali Peter
- Metrakos Peter
- Neuschwander-Tetri Brent A
- Patel Keyur
- Petta Salvatore
- Pinzani Massimo
- Ramji Alnoor
- Ratziu Vlad
- Sebastiani Giada
- Seto Karen
- Shoukry Naglaa
- Stone James
- Swain Mark G
- Tang An
- Watson Heather
- Publication venue
- 'University of Toronto Press Inc. (UTPress)'
- Publication date
- 01/01/2022
- Field of study
Non-alcoholic fatty liver disease (NAFLD) affects approximately 8 million Canadians. NAFLD refers to a disease spectrum ranging from bland steatosis to non-alcoholic steatohepatitis (NASH). Nearly 25% of patients with NAFLD develop NASH, which can progress to liver cirrhosis and related end-stage complications. Type 2 diabetes and obesity represent the main risk factors for the disease. The Canadian NASH Network is a national collaborative organization of health care professionals and researchers with a primary interest in enhancing understanding, care, education, and research around NAFLD, with a vision of best practices for this disease state. At the 1st International Workshop of the CanNASH network in April 2021, a joint event with the single topic conference of the Canadian Association for the Study of the Liver (CASL), clinicians, epidemiologists, basic scientists, and community members came together to share their work under the theme of NASH. This symposium also marked the initiation of collaborations between Canadian and other key opinion leaders in the field representative of international liver associations. The main objective is to develop a policy framework that outlines specific targets, suggested activities, and evidence-based best practices to guide provincial, territorial, and federal organizations in developing multidisciplinary models of care and strategies to address this epidemic
Egocentric Social Network Structure, Health, and Pro-Social Behaviors in a National Panel Study of Americans
- Author
- A. James OâMalley
- AJ OâMalley
- B Wellman
- Darby Miller Steiger
- EO Laumann
- EO Laumann
- EO Laumann
- J Cooper
- James H. Fowler
- JH Fowler
- JH Fowler
- JS House
- KM Harris
- KP Smith
- M McPherson
- MatjaĹž Perc
- MJ Lubbers
- N Eisenberg
- NA Christakis
- NA Christakis
- NA Christakis
- Nicholas A. Christakis
- PV Marsden
- PV Marsden
- PV Marsden
- R Dunbar
- RS Burt
- Samuel Arbesman
- SL Feld
- TW Smith
- U Matzat
- Publication venue
- Public Library of Science
- Publication date
- 01/01/2012
- Field of study
Using a population-based, panel survey, we study how egocentric social networks change over time, and the relationship between egocentric network properties and health and pro-social behaviors. We find that the number of prosocial activities is strongly positively associated with having more friends, or an increase in degree, with approximately 0.04 more prosocial behaviors expected for every friend added. Moreover, having more friends is associated with an improvement in health, while being healthy and prosocial is associated with closer relationships. Specifically, a unit increase in health is associated with an expected 0.45 percentage-point increase in average closeness, while adding a prosocial activity is associated with a 0.46 percentage-point increase in the closeness of oneâs relationships. Furthermore, a tradeoff between degree and closeness of social contacts was observed. As the number of close social contacts increases by one, the estimated average closeness of each individual contact decreases by approximately three percentage-points. The increased awareness of the importance of spillover effects in health and health care makes the ascertainment of egocentric social networks a valuable complement to investigations of the relationship between socioeconomic factors and health
Constraints on the Ď_(c1) versus Ď_(c2) polarizations in proton-proton collisions at âs = 8 TeV
- Author
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
- Abdullin S.
- Abercrombie D.
- Acharya H.
- Acosta D.
- Acosta J.âG.
- Adam W.
- Adams M.âR.
- Adams T.
- Adzic P.
- Afanasiev S.
- Agapitos A.
- Agarwal G.
- Aggleton R.
- Agram J.-L.
- Aguilar-Benitez M.
- Ahmad A.
- Ahmad M.
- Ahmad M.
- Ahuja S.
- Akbiyik M.
- Akchurin N.
- Akgun B.
- Albajar C.
- Albergo S.
- Albert A.
- Albrow M.
- Alcaraz Maestre J.
- Aldaya Martin M.
- Aleksandrov A.
- Alexander J.
- Alhusseini M.
- Alimena J.
- Alison J.
- Allen B.
- Almond J.
- Alvarez Gonzalez B.
- Alverson G.
- Alves G.âA.
- Aly R.
- Alyari M.
- Amapane N.
- Ambrogi F.
- Amendola C.
- Amin N.
- Amsler C.
- Anagnostou G.
- Anderson D.
- Andrea J.
- Andreev V.
- Andreev Yu.
- Andrews M.âB.
- Androsov K.
- Ang L.
- Antchev G.
- Antunovic Z.
- Apanasevich L.
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- Atakisi I.âO.
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- Zorbakir I.âS.
- Zorbilmez C.
- Zotto P.
- Zou D.
- Zucchetta A.
- Zumerle G.
- Zuo X.
- Zuolo D.
- Ălvarez FernĂĄndez A.
- Ăzçelik Ă.
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 24/04/2020
- Field of study
The polarizations of promptly produced Ď_(c1) and Ď_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at âs=8ââTeV. The Ď_c states are reconstructed via their radiative decays Ď_c â J/ĎÎł, with the photons being measured through conversions to eâşeâť, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the Ď_(c2) to Ď_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/Ď â ÎźâşÎźâť decay, in three bins of J/Ď transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum
X-ray emission from the Sombrero galaxy: discrete sources
- Author
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- Abbiendi G
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- Taurok A
- Tauscher L
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- Taylor L
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- Teischinger F
- Temple J
- Tenchini R
- Teng H
- Teo WD
- Teodorescu L
- Terentyev N
- Teyssier D
- Thea A
- Theofilatos K
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- Thom J
- Thomas L
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- Thomsen J
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- Tomalin IR
- Tomaszewska J
- Tomei TRFP
- Tonelli G
- Tonjes MB
- Tonwar SC
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- Topaksu AK
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- Troendle D
- Troitsky S
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- Tropiano A
- Troshin S
- Tsang KV
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- Tsirou A
- Tsyganov A
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- Veszpremi V
- Vesztergombi G
- Veverka J
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- Wissing C
- Wittich P
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- Womersley WJ
- Won S
- Wood D
- Wood JS
- Worm SD
- Wright D
- Wrochna G
- Wu JH
- Wu W
- Wulz CE
- Wurthwein F
- Wyslouch B
- Xiao H
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- Yilmaz Y
- Yohay R
- Yoo HD
- Yoon AS
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- Yu I
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
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- Zheng Y
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- Zhu B
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- Zhukov V
- Zhukova V
- Ziebarth EB
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- Zoeller MH
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- Zumerle G
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- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2010
- Field of study
We present a study of discrete X-ray sources in and around the
bulge-dominated, massive Sa galaxy, Sombrero (M104), based on new and archival
Chandra observations with a total exposure of ~200 ks. With a detection limit
of L_X = 1E37 erg/s and a field of view covering a galactocentric radius of ~30
kpc (11.5 arcminute), 383 sources are detected. Cross-correlation with Spitler
et al.'s catalogue of Sombrero globular clusters (GCs) identified from HST/ACS
observations reveals 41 X-rays sources in GCs, presumably low-mass X-ray
binaries (LMXBs). We quantify the differential luminosity functions (LFs) for
both the detected GC and field LMXBs, whose power-low indices (~1.1 for the
GC-LF and ~1.6 for field-LF) are consistent with previous studies for
elliptical galaxies. With precise sky positions of the GCs without a detected
X-ray source, we further quantify, through a fluctuation analysis, the GC LF at
fainter luminosities down to 1E35 erg/s. The derived index rules out a
faint-end slope flatter than 1.1 at a 2 sigma significance, contrary to recent
findings in several elliptical galaxies and the bulge of M31. On the other
hand, the 2-6 keV unresolved emission places a tight constraint on the field
LF, implying a flattened index of ~1.0 below 1E37 erg/s. We also detect 101
sources in the halo of Sombrero. The presence of these sources cannot be
interpreted as galactic LMXBs whose spatial distribution empirically follows
the starlight. Their number is also higher than the expected number of cosmic
AGNs (52+/-11 [1 sigma]) whose surface density is constrained by deep X-ray
surveys. We suggest that either the cosmic X-ray background is unusually high
in the direction of Sombrero, or a distinct population of X-ray sources is
present in the halo of Sombrero.Comment: 11 figures, 5 tables, ApJ in pres
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