154 research outputs found

    STUDI PENGARUH AIR LAUT PADA MORTAR BETON NORMAL DAN MORTAR BETON DENGAN FLY ASH

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    Abstract: Fly ash is the residue of coal combustion in the form of grain which is transported by exhaust gas which can be used in the mortar and concrete manufacture. One of the main source of fly ash is the result of coal combustion at Tanjung Jati B power plant in Jepara. The purpose of this research is to observe fly ash-based mortar behavior toward compressive strength, flexural tensile strength, and absorption by substitution of cement with 20% fly ash precentage of mass ratio followed by immersion with freshwater and sea water taken from Jepara waters. this is used for the compressive strength of the cube 50 x 50 x 50 mm (ASTM C109 / C109M - 16), test specimens for testing the bending strength of 40 x 40 x 160 mm (ASTM C348 - 14), and 100 x 200 cylinders mm for observation of absorption behavior (ASTM C1585 - 13). Non-fly ash test specimens soaked in fresh water act as controls. Non-soaked seawater asphalt test subjects produce the highest compressive strength, but the speci-mens with freshwater-immersed fly ash show no higher yield. In contrast to the compressive strength results, the seawater-impregnated test specimens yield the lowest tensile strength, while the presence of fly ash in other test specimens has little effect. In the absorption test, the use of fly ash mortar with sea water bath resulted in increased velocity and absorption rate, whereas fly ash on specimens soaked in fresh water did not have a significant effect on the mortar absorption behavior. Abstrak: Fly ash adalah sisa hasil pembakaran batu bara berupa butir halus yang diangkut oleh gas buang yang dapat digunakan dalam pembuatan mortar dan beton. Salah satu sumber fly ash adalah hasil pembakaran batubara di PLTU Tanjung Jati B Jepara. Tujuan dari penelitian ini adalah untuk mengamati perilaku mortar berbasis fly ash terhadap kuat tekan, kuat tarik lentur, dan absorpsinya dengan melakukan substitusi semen dengan prosentase fly ash20% dari per-bandingan massa diikuti perendaman dengan air tawar dan air laut yang diambil dari perairan Jepara.Dalam penelitian ini digunakan benda uji untukkuat tekan berupa kubus 50 x 50 x 50 mm (ASTM C109/C109M – 16), benda uji untuk pengujian kuat tarik lentur berbentuk balok 40 x 40 x 160 mm (ASTM C348 – 14), dan silinder 100 x 200 mm untuk pengamatan perilaku absorpsi (ASTM C1585 – 13). Benda uji tanpa fly ash yang direndam dengan air tawar bertin-dak sebagai benda uji kontrol. Benda uji tanpa fly ash yang direndam air laut menghasilkan kuat tekan tertinggi, tetapi benda uji dengan fly ash yang direndam air tawar tidak menunjuk-kan hasil yang lebih tinggi. Berbeda dengan hasil kuat tekan, benda uji tanpa fly ash yang direndam air laut menghasilkan kuat tarik lentur terendah, sedangkan keberadaan fly ash pada benda uji kategori lain memberikan dampak yang kecil. Dalam pengujian absorpsi, penggunaan mortar dengan fly ash dengan rendaman air laut mengakibatkanpeningkatkan ke-cepatan dan tingkat absorpsi, sedangkan fly ash pada benda uji yang direndam dengan air tawar tidak memberikan pengaruh yang berarti dalam perilaku absorpsi mortar

    Re-traumatization of torture survivors during treatment in somatic healthcare services: A mapping review and appraisal of literature presenting clinical guidelines and recommendations to prevent re-traumatization

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    Abstract Rationale The number of torture survivors is on the rise, posing issues for their care in healthcare settings. Even healthcare experts with training in refugee care are unaware of the health difficulties faced by torture survivors. Any medical evaluation or treatment has the potential to re-traumatize torture survivors, thereby reactivating trauma symptoms without applicable guidelines to prevent re-traumatization. Objective Our objective was to identify, characterize, evaluate, and organize current, available evidence presenting existing recommendations and suggestions to prevent re-traumatization during the treatment of torture survivors’ physical diseases in healthcare services. Methods A comprehensive search of electronic databases was conducted. Gray literature coverage was obtained by searching for publications from relevant associations and healthcare organizations focusing on torture survivors. Clinical practice guidelines (CPGs) and research focusing on somatic healthcare services for adult torture survivors, regardless of study design, were eligible for review. Studies that concentrated on psychiatric departments were excluded. To conduct an overview of the available research and describe the scope and distribution of evidence, a mapping review methodology was used. Results Forty out of 13,111 initial citations met our criteria. There were two guidelines, and text and opinion statements predominated. Two authors independently assessed the risk of bias in each primary research study using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for the research design. Conclusions This mapping review identifies triggers that may re-traumatize torture survivors during treatment and makes recommendations for prevention. Only a few studies have considered torture survivors' perspectives on treatment and re-traumatization. According to the findings of the mapping review, healthcare providers should consider survivors’ biopsychosocial situations, cultural sensitivity, and personal attitude changes. They must also identify tortured patients and determine when professional interpreters should be used

    Development and evaluation of a web-based breast cancer cultural competency course for primary healthcare providers

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    <p>Abstract</p> <p>Background</p> <p>To develop and evaluate a continuing medical education (CME) course aimed at improving healthcare provider knowledge about breast cancer health disparities and the importance of cross-cultural communication in provider-patient interactions about breast cancer screening.</p> <p>Methods</p> <p>An interactive web-based CME course was developed and contained information about breast cancer disparities, the role of culture in healthcare decision making, and demonstrated a model of cross-cultural communication. A single group pre-/post-test design was used to assess knowledge changes. Data on user satisfaction was also collected.</p> <p>Results</p> <p>In all, 132 participants registered for the CME with 103 completing both assessments. Differences between pre-/post-test show a significant increase in knowledge (70% vs. 94%; p < .001). Ninety-five percent of participants agreed that the web based training was an appropriate tool to train healthcare providers about cultural competency and health disparities.</p> <p>Conclusion</p> <p>There was an overall high level of satisfaction among all users. Users felt that learning objectives were met and the web-based format was appropriate and easy to use and suggests that web-based CME formats are an appropriate tool to teach cultural competency skills. However, more information is needed to understand how the CME impacted practice behaviors.</p

    Praksisstudienes omfang og organisering i bioingeniørutdanningen

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    Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. Både tidligere rammeplan og nye retningslinjer har regulert læringsutbyttene og omfang av praksis i utdanningen. I denne studien kartlegges omfang og organisering av praksisstudiene ved de ulike studieprogrammene, dette for å undersøke forskjeller og likheter og tilrettelegge for at studiestedene kan lære av hverandre. Det er innhentet data fra hvert studieprogram for omfang og organisering av veiledet intern praksis, ekstern praksis samt bacheloroppgaven. Dette ble kartlagt for alle studiestedene før og etter innføring av nye retningslinjer. Resultatene viser ulikheter i omfang og organisering av praksisstudiene og bacheloroppgaven mellom studieprogrammene i Norge og da særlig i organisering av intern praksis. De nye retningslinjene åpner samtidig opp for en videre fortolkning av praksisbegrepet og av krav til omfang og organisering av praksis. For å sikre likeverdig sluttkompetanse for ferdigutdannede, uavhengig av studiested, er det behov for i større grad enes om hva som gir tilstrekkelig omfang og god kvalitet i praksis i bioingeniørutdanningen. Denne deskriptive studien viser behov for videre forskningssamarbeid mellom studiestedene, for å utvikle en bioingeniørutdanning av best mulig kvalitet for fremtiden.publishedVersio

    Praksisstudienes omfang og organisering i bioingeniørutdanningen

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    Source at https://www.bioingenioren.no/arkiv/.Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. Både tidligere rammeplan og nye retningslinjer har regulert læringsutbyttene og omfang av praksis i utdanningen. I denne studien kartlegges omfang og organisering av praksisstudiene ved de ulike studieprogrammene, dette for å undersøke forskjeller og likheter og tilrettelegge for at studiestedene kan lære av hverandre. Det er innhentet data fra hvert studieprogram for omfang og organisering av veiledet intern praksis, ekstern praksis samt bacheloroppgaven. Dette ble kartlagt for alle studiestedene før og etter innføring av nye retningslinjer. Resultatene viser ulikheter i omfang og organisering av praksisstudiene og bacheloroppgaven mellom studieprogrammene i Norge og da særlig i organisering av intern praksis. De nye retningslinjene åpner samtidig opp for en videre fortolkning av praksisbegrepet og av krav til omfang og organisering av praksis. For å sikre likeverdig sluttkompetanse for ferdigutdannede, uavhengig av studiested, er det behov for i større grad enes om hva som gir tilstrekkelig omfang og god kvalitet i praksis i bioingeniørutdanningen. Denne deskriptive studien viser behov for videre forskningssamarbeid mellom studiestedene, for å utvikle en bioingeniørutdanning av best mulig kvalitet for fremtiden

    Praksisstudienes omfang og organisering i bioingeniørutdanningen

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    Since 2005, scope and content of the biomedical laboratory scientist education have been defined by national guidelines to ensure equal final competence for all candidates. From 2019, a new regulation on national guidelines was approved. Both new and old guidelines have regulated the learning outcomes and scope of practice in education. In this study, the scope and organization of the practical studies at the various study programs are characterized, in order to investigate differences and similarities and to facilitate that the study programs can learn from each other. Data has been obtained from each study program for the scope and organization of supervised internal practice, external practice and the bachelor thesis are reported for all study programs before and after the introduction of new guidelines. This study shows differences in the scope and organization of the practice and the bachelor thesis between the study programs in Norway and especially in the organization of internal practice. At the same time, the new guidelines open up for a further interpretation of the concept of practice and of requirements for the scope and organization of practice. In order to ensure equal final competence for the graduates, regardless of place of study, there is a need to agree to a greater extent on what provides sufficient scope and good quality of clinical practice in the study programs of biomedical laboratory scientists. This descriptive study shows the need for further research collaboration between the educational institutions, in order to develop a biomedical laboratory scientist education of the best possible quality for the future.publishedVersio

    Praksisstudienes omfang og organisering i bioingeniørutdanningen

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    Siden 2005 har omfang og innhold i bioingeniørutdanningen vært definert av en nasjonal rammeplan for å sikre likeverdig sluttkompetanse for alle kandidater. Fra 2019 ble en ny forskrift om nasjonale retningslinjer fastsatt. Både tidligere rammeplan og nye retningslinjer har regulert læringsutbyttene og omfang av praksis i utdanningen. I denne studien kartlegges omfang og organisering av praksisstudiene ved de ulike studieprogrammene, dette for å undersøke forskjeller og likheter og tilrettelegge for at studiestedene kan lære av hverandre. Det er innhentet data fra hvert studieprogram for omfang og organisering av veiledet intern praksis, ekstern praksis samt bacheloroppgaven. Dette ble kartlagt for alle studiestedene før og etter innføring av nye retningslinjer. Resultatene viser ulikheter i omfang og organisering av praksisstudiene og bacheloroppgaven mellom studieprogrammene i Norge og da særlig i organisering av intern praksis. De nye retningslinjene åpner samtidig opp for en videre fortolkning av praksisbegrepet og av krav til omfang og organisering av praksis. For å sikre likeverdig sluttkompetanse for ferdigutdannede, uavhengig av studiested, er det behov for i større grad enes om hva som gir tilstrekkelig omfang og god kvalitet i praksis i bioingeniørutdanningen. Denne deskriptive studien viser behov for videre forskningssamarbeid mellom studiestedene, for å utvikle en bioingeniørutdanning av best mulig kvalitet for fremtiden.publishedVersio

    Major histocompatibility complex associations of ankylosing spondylitis are complex and involve further epistasis with ERAP1

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    Ankylosing spondylitis (AS) is a common, highly heritable, inflammatory arthritis for which HLA-B*27 is the major genetic risk factor, although its role in the aetiology of AS remains elusive. To better understand the genetic basis of the MHC susceptibility loci, we genotyped 7,264 MHC SNPs in 22,647 AS cases and controls of European descent. We impute SNPs, classical HLA alleles and amino-acid residues within HLA proteins, and tested these for association to AS status. Here we show that in addition to effects due to HLA-B*27 alleles, several other HLA-B alleles also affect susceptibility. After controlling for the associated haplotypes in HLA-B, we observe independent associations with variants in the HLA-A, HLA-DPB1 and HLA-DRB1 loci. We also demonstrate that the ERAP1 SNP rs30187 association is not restricted only to carriers of HLA-B*27 but also found in HLA-B*40:01 carriers independently of HLA-B*27 genotype

    DMTs and Covid-19 severity in MS: a pooled analysis from Italy and France

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    We evaluated the effect of DMTs on Covid-19 severity in patients with MS, with a pooled-analysis of two large cohorts from Italy and France. The association of baseline characteristics and DMTs with Covid-19 severity was assessed by multivariate ordinal-logistic models and pooled by a fixed-effect meta-analysis. 1066 patients with MS from Italy and 721 from France were included. In the multivariate model, anti-CD20 therapies were significantly associated (OR&nbsp;=&nbsp;2.05, 95%CI&nbsp;=&nbsp;1.39–3.02, p&nbsp;&lt;&nbsp;0.001) with Covid-19 severity, whereas interferon indicated a decreased risk (OR&nbsp;=&nbsp;0.42, 95%CI&nbsp;=&nbsp;0.18–0.99, p&nbsp;=&nbsp;0.047). This pooled-analysis confirms an increased risk of severe Covid-19 in patients on anti-CD20 therapies and supports the protective role of interferon
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