1,192 research outputs found
Resetting a functional G1 nucleus after mitosis
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2016
- Field of study
© The Author(s) 2015. The maintenance of the correct cellular information goes beyond the simple transmission of an intact genetic code from one generation to the next. Epigenetic changes, topological cues and correct protein-protein interactions need to be re-established after each cell division to allow the next cell cycle to resume in the correct regulated manner. This process begins with mitotic exit and re-sets all the changes that occurred
during mitosis thus restoring a functional G1 nucleus in preparation for the next cell cycle. Mitotic exit is triggered by inactivation of mitotic kinases and the reversal of their phosphorylation activities on many cellular components, from nuclear lamina to transcription factors and chromatin itself. To reverse all these phosphorylations, phosphatases act during mitotic exit in a timely and spatially controlled manner directing the events that lead to a functional G1 nucleus. In this review, we will summarise the recent developments on the
control of phosphatases and their known substrates during mitotic exit, and the key steps that control the restoration of chromatin status, nuclear envelope reassembly and nuclear body re-organisation. Although pivotal work has been conducted in this area in yeast, due to differences between the mitotic exit network between yeast and vertebrates, we will mainly concentrate on the vertebrate system.BBSRC grant (BB/K017632/1)
Is there a role for glucocorticoid receptor beta in asthma?
- Author
- Publication venue
- BioMed Central
- Publication date
- 01/12/2000
- Field of study
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding pro-inflammatory mediators. A hormone binding deficient GR isoform named GRβ has been isolated in humans. When overexpressed by transfection, GRβ may function as a dominant negative modulator of GRα. However, to act as such, GRβ has to be more abundant than GRα, and conflicting data have been obtained concerning the relative levels of the two isoforms in cell lines and freshly isolated cells. Moreover, the dominant negative effect was not confirmed by independent laboratories. In GC-resistant asthmatics, GRβ was expressed by an increased number of peripheral blood mononuclear cells (PBMCs), airway T cells, and cells found in skin biopsies of tuberculin responses. However, the relative amounts of GRα and GRβ in these cells were not determined. In GC-dependent asthmatics, PBMCs expressed GRα predominantly. No cells containing higher levels of GRβ than GRα have yet been reported in asthmatics. Even if the existence of such cells is demonstrated, the role of GRβ in asthma will remain a matter of controversy because functional studies have given discrepant data
A retinal code for motion along the gravitational and body axes
- Author
- A Cruz-Martín
- A Szél
- AD Huberman
- Ananya Bhatia-Lin
- BG Borghuis
- BG Borghuis
- BS Oommen
- CW Oyster
- CW Oyster
- David M. Berson
- DE Angelaki
- DE Angelaki
- DE Nilsson
- DJ Wallace
- F Naarendorp
- G Yang
- Gabriel Castro
- Gabrielle Manoff
- H Ding
- IJ Kim
- JB Demb
- Jesse K. Siegel
- JI Simpson
- JI Simpson
- JMK Kwong
- JN Kay
- John A. Gemmer
- JS Kim
- K Yonehara
- KL Briggman
- LT Maloney
- M Rivlin-Etzion
- N Oesch
- Nathan Jeffery
- OS Dhande
- R Kanjhan
- RE Kass
- S Trenholm
- S Venkataramani
- Shai Sabbah
- SJ Park
- SW Oh
- TW Chen
- VI Govardovskii
- W Wei
- WR Taylor
- X Dai
- YC Chan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 05/06/2017
- Field of study
Self-motion triggers complementary visual and vestibular reflexes supporting image-stabilization and balance. Translation through space produces one global pattern of retinal image motion (optic flow), rotation another. We examined the direction preferences of direction-sensitive ganglion cells (DSGCs) in flattened mouse retinas in vitro. Here we show that for each subtype of DSGC, direction preference varies topographically so as to align with specific translatory optic flow fields, creating a neural ensemble tuned for a specific direction of motion through space. Four cardinal translatory directions are represented, aligned with two axes of high adaptive relevance: the body and gravitational axes. One subtype maximizes its output when the mouse advances, others when it retreats, rises or falls. Two classes of DSGCs, namely, ON-DSGCs and ON-OFF-DSGCs, share the same spatial geometry but weight the four channels differently. Each subtype ensemble is also tuned for rotation. The relative activation of DSGC channels uniquely encodes every translation and rotation. Although retinal and vestibular systems both encode translatory and rotatory self-motion, their coordinate systems differ
Respostas cardiopulmonares agudas de mulheres no treinamento de força
- Author
- Atomi Y
- Bishop D
- Bizen CA
- Brown LE
- Cesar MC
- Cesar MC
- Dionne IJ
- Elsangedy HM
- Furtado E
- Gabriel Soliani Celante
- Glowacki SP
- Hoff J
- Hunter GR
- Hurley BF
- João Paulo Borin
- Karvonen M
- Kraemer WJ
- Kraemer WJ
- Marcelo de Castro Cesar
- Maria Imaculada de Lima Montebelo
- Márcio Antônio Gonsalves Sindorf
- Pamela Roberta Gomes Gonelli
- Parker SB
- Phillips WT
- Phillips WT
- Redman LM
- Ricardo Adamoli Simões
- Rixon KP
- Schmitz KH
- Souza TMF
- Thiago Mattos Frota de Souza
- Wasserman K
- Wasserman K
- Williams M.A.
- Wilmore JH
- Publication venue
- 'FapUNIFESP (SciELO)'
- Publication date
- Field of study
HPV16 oncogene expression levels during early cervical carcinogenesis are determined by the balance of epigenetic chromatin modifications at the integrated virus genome.
- Author
- A Carson
- AJ Bannister
- C G Scarpini
- C Johansson
- CA Hazzalin
- CG Scarpini
- CH Kim
- CW Yew
- D Forman
- E Gray
- E Johannsen
- E L A Knight
- F Friedl
- G Li
- GM Euskirchen
- H He
- HU Bernard
- I J Groves
- IJ Groves
- IJ Groves
- J De-Castro Arce
- J Vandesompele
- JA Smith
- JE Hanning
- JE Hanning
- JE Hanning
- JM Simon
- KL Dall
- KW Jeong
- LM del Mar Pena
- M Pett
- M Xu
- MA Bedell
- MA Stanley
- ME McLaughlin-Drubin
- MH Stoler
- MR Pett
- MT Herdman
- MW Pfaffl
- N Coleman
- N Coleman
- N Coleman
- N Wentzensen
- N Wentzensen
- O Bogdanovic
- PL Hyland
- Q Y Ang
- RD Palermo
- S Jeon
- S Jha
- S Wang
- SH Chao
- TK Kelly
- TR Wooldridge
- U Kruppel
- W Stunkel
- WM Wang
- Y Dou
- Y Sun
- Y Zhu
- Z Wang
- Publication venue
- Oncogene
- Publication date
- 15/02/2016
- Field of study
In cervical squamous cell carcinomas, high-risk human papillomavirus (HRHPV) DNA is usually integrated into host chromosomes. Multiple integration events are thought to be present within the cells of a polyclonal premalignant lesion and the features that underpin clonal selection of one particular integrant remain poorly understood. We previously used the W12 model system to generate a panel of cervical keratinocyte clones, derived from cells of a low-grade premalignant lesion naturally infected with the major HRHPV type, HPV16. The cells were isolated regardless of their selective advantage and differed only by the site of HPV16 integration into the host genome. We used this resource to test the hypothesis that levels of HPV16 E6/E7 oncogene expression in premalignant cells are regulated epigenetically. We performed a comprehensive analysis of the epigenetic landscape of the integrated HPV16 DNA in selected clones, in which levels of virus oncogene expression per DNA template varied ~6.6-fold. Across the cells examined, higher levels of virus expression per template were associated with more open chromatin at the HPV16 long control region, together with greater loading of chromatin remodelling enzymes and lower nucleosome occupancy. There were higher levels of histone post-translational modification hallmarks of transcriptionally active chromatin and lower levels of repressive hallmarks. There was greater abundance of the active/elongating form of the RNA polymerase-II enzyme (RNAPII-Ser2P), together with CDK9, the component of positive transcription elongation factor b complex responsible for Ser2 phosphorylation. The changes observed were functionally significant, as cells with higher HPV16 expression per template showed greater sensitivity to depletion and/or inhibition of histone acetyltransferases and CDK9 and less sensitivity to histone deacetylase inhibition. We conclude that virus gene expression per template following HPV16 integration is determined through multiple layers of epigenetic regulation, which are likely to contribute to selection of individual cells during cervical carcinogenesis.This work was supported by Cancer Research UK (Programme Grant A13080); the Medical Research Council; The Pathological Society of Great Britain and Ireland (E.L.A.K.); and the Agency for Science, Technology and Research, Singapore (Q.Y.A).This is the final version of the article. It first appeared from Nature Publishing Group via http://dx.doi.org/10.1038/onc.2016.
Search for the standard model Higgs boson at LEP
- Author
- Abbaneo D
- Abbaneo D
- Abbiendi G
- Abbiendi G
- Abdallah J
- Abreu P
- Achard P
- Adam W
- Adriani O
- Adzic P
- Affholderbach K
- Aguilar-Benitez M
- Ainsley C
- Akesson PF
- Albrecht T
- Alcaraz J
- Alderweireld T
- Alemanni G
- Alemany-Fernandez R
- Alexander G
- Allaby J
- Allison J
- Allmendinger T
- Allport PP
- Aloisio A
- Alviggi MG
- Amaldi U
- Amapane N
- Amaral P
- Amato S
- Anagnostou G
- Anashkin E
- Anderhub H
- Anderson KJ
- Andreazza A
- Andreev VP
- Andringa S
- Anjos N
- Anselmo F
- Antilogus P
- Antonelli A
- Antonelli M
- Apel WD
- Arcelli S
- Arefiev A
- Armstrong SR
- Arnoud Y
- Asai S
- Ask S
- Asman B
- Augustin JE
- Augustinus A
- Awunor O
- Axen D
- Azemoon T
- Aziz T
- Azuelos G
- Azzurri P
- Baarmand M
- Badaud F
- Bagliesi G
- Bagnaia P
- Bailey I
- Baillon P
- Bajo A
- Baksay G
- Baksay L
- Baldew SV
- Ballestrero A
- Bambade P
- Banerjee S
- Banerjee S
- Barate R
- Barate R
- Barberio E
- Barbier R
- Barczyk A
- Bardin D
- Barillere R
- Barker G
- Barklow T
- Barlow RJ
- Baroncelli A
- Bartalini P
- Basile M
- Batalova N
- Batley RJ
- Battaglia M
- Battiston R
- Baubillier M
- Bay A
- Becattini F
- Bechtle P
- Becker U
- Becks KH
- Begalli M
- Behner F
- Behnke T
- Behrmann A
- Bell KW
- Bell PJ
- Bella G
- Bellerive A
- Bellucci L
- Ben-Haim E
- Bencivenni G
- Benekos N
- Benelli G
- Benvenuti A
- Berat C
- Berbeco R
- Berdugo J
- Berges P
- Berggren M
- Berkelman K
- Berntzon L
- Bertrand D
- Bertucci B
- Besancon M
- Besson N
- Betev BL
- Bethke S
- Beuselinck R
- Biasini M
- Biebell O
- Biglietti M
- Biland A
- Binnie DM
- Blair GA
- Blaising JJ
- Bloch D
- Bloch-Devaux B
- Blom M
- Blondel A
- Bloodworth IJ
- Bluj M
- Blumenschein U
- Blyth SC
- Bobbink GJ
- Boccali T
- Bock P
- Boeriun O
- Bohm A
- Bohrer A
- Boix G
- Boldizsar L
- Bologna G
- Bonacorsi D
- Bonesini M
- Bonissent A
- Boonekamp M
- Booth CN
- Booth PSL
- Borean C
- Borgia B
- Borisov G
- Bossi F
- Botner O
- Boucrot J
- Bouhova-Thacker E
- Boumediene D
- Bouquet B
- Bourilkov D
- Bourquin M
- Boutemeur M
- Bowcock TJV
- Bowdery CK
- Boyko I
- Braccini S
- Bracko M
- Braibant S
- Brandt S
- Branson JG
- Bravo S
- Brenner R
- Brient JC
- Brigliadori L
- Brochu F
- Brodet E
- Brown RM
- Bruckman P
- Bruneliere R
- Brunet JM
- Buchmuller O
- Buesser K
- Bugge L
- Buijs A
- Burckhart HJ
- Burger JD
- Burger WJ
- Buschmann P
- Cai XD
- Callot O
- Calvi M
- Cameron W
- Campana R
- Campana S
- Camporesi T
- Canale V
- Capell M
- Capon G
- Carena F
- Carlino G
- Carnegie RK
- Caron B
- Carr J
- Cartacci A
- Carter AA
- Carter JR
- Cartwright S
- Casado MP
- Casaus J
- Castro N
- Cattaneo A
- Cavallari F
- Cavallo F
- Cavallo N
- Cavanaugh R
- Cecchi C
- Cerrada M
- Cerutti F
- Chamizo M
- Chang CY
- Chang YH
- Chapkin M
- Charlton DG
- Charpentier P
- Checchia P
- Chemarin M
- Chen A
- Chen G
- Chen GM
- Chen HF
- Chen HS
- Chiarella V
- Chiefari G
- Chierici R
- Chiliapnikov P
- Chmeissani M
- Chudoba J
- Chung SU
- Cieslik K
- Cifarelli L
- Cindolo F
- Ciulli V
- Clare I
- Clare R
- Clarke DP
- Clerbaux B
- Clifft RW
- Coignet G
- Colaleo A
- Colas P
- Coles J
- Colino N
- Collins P
- Combley F
- Contri R
- Cosme G
- Cossutti F
- Costa MJ
- Costantini S
- Cowan G
- Coyle P
- Cranmer K
- Crawley B
- Creanza D
- Crennell D
- Crespo JM
- Csilling A
- Cucciarelli S
- Cuevas J
- Cuffiani M
- Curtil C
- D'Hondt J
- da Silva T
- Da Silva W
- Dado S
- Dai TS
- Dallavalle GM
- Dallison S
- Dalmau J
- David A
- Davier M
- Davies G
- De Angelis A
- de Asmundis R
- De Boer W
- De Bonis I
- De Clercq C
- De Filippis N
- de Guevara PL
- de Jong R
- de la Cruz B
- De Lotto B
- De Maria N
- De Min A
- de Palma M
- de Paula L
- De Roeck A
- De Salvo A
- De Vivie de Regie JB
- De Wolf EA
- Debreczeni J
- Decamp D
- Deglon P
- Degre A
- Deiters K
- Della Ricca G
- della Volpe D
- Delmeire E
- Denes P
- DeNotaristefani F
- Desch K
- Dessagne S
- Dhamotharan S
- Di Ciaccio L
- Di Simone A
- Diemoz M
- Dienes B
- Dierckxsens M
- Dietl H
- Dionisi C
- Dissertori G
- Dittmar M
- Donkers M
- Doria A
- Dornan PJ
- Doroba K
- Dova MT
- Drees J
- Drevermann H
- Dris M
- Dubbert J
- Duchesneau D
- Duchovni E
- Duckeck G
- Duerdoth IP
- Duflot L
- Duinker P
- Ealet A
- Echenard B
- Edgecock TR
- Eigen G
- Ekelof T
- El Mamouni H
- Elfgren E
- Eline A
- Ellert M
- Ellis G
- Elsing M
- Engler A
- Eppling FJ
- Etzion E
- Ewers A
- Extermann P
- Fabbri F
- Fabbro B
- Falagan MA
- Falciano S
- Falvard A
- Fanourakis G
- Fassouliotis D
- Favara A
- Fay J
- Fayolle D
- Fedin O
- Feindt M
- Felcini M
- Feld L
- Ferguson DPS
- Ferguson T
- Fernandez E
- Fernandez J
- Fernandez-Bosman M
- Ferrari P
- Ferrer A
- Ferro F
- Fesefeldt H
- Fiandrini E
- Fiedler F
- Field JH
- Filthaut F
- Finch AJ
- Fisher PH
- Fisher W
- Fisk I
- Flagmeyer U
- Fleck I
- Foa L
- Focardi E
- Foeth H
- Fokitis E
- Forconi G
- Ford M
- Forty RW
- Foster F
- Fouchez D
- Frank M
- Freudenreich K
- Frey A
- Fulda-Quenzer F
- Furetta C
- Furtjes A
- Fuster J
- Gagnon P
- Galaktionov Y
- Gandelman M
- Ganguli SN
- Ganis G
- Gao Y
- Garcia C
- Garcia-Abia P
- Garcia-Bellido A
- Garrido L
- Gary JW
- Gataullin M
- Gavillet P
- Gay P
- Gaycken G
- Gazis E
- Geich-Gimbel C
- Gentile S
- Geweniger C
- Ghete VM
- Giacomelli G
- Giacomelli P
- Giagu S
- Giammanco A
- Giannini G
- Gianotti F
- Giassi A
- Girone M
- Girtler P
- Giunta M
- Gokieli R
- Goldberg J
- Golob B
- Gomez-Ceballos G
- Goncalves P
- Gong ZF
- Gonzalez S
- Goy C
- Grauges E
- Graziani E
- Green MG
- Greening TC
- Grenier G
- Grimm O
- Grivaz JF
- Grosdidier G
- Gross E
- Gruenewald MW
- Grunhaus J
- Grupen C
- Gruwe M
- Grzelak K
- Guida M
- Gunther PO
- Gupta A
- Gupta VK
- Gurtu A
- Gutay LJ
- Guy J
- Haag C
- Haas D
- Hajdu C
- Hallgren A
- Hamacher K
- Hamann M
- Hamilton K
- Hanke P
- Hansen J
- Hansen JB
- Hansen JD
- Hansen JR
- Hansen PH
- Hanson GG
- Harder K
- Harel A
- Harin-Dirac M
- Harvey J
- Hatzifotiadou D
- Haug S
- Hauler F
- Hauschild M
- Hauschildt J
- Hawkes CM
- Hawkings R
- Hayes OJ
- He H
- Hebbeker T
- Hedberg V
- Heister A
- Hemingway RJ
- Henneche M
- Hensel C
- Hepp V
- Herr H
- Herten G
- Herve A
- Hess J
- Heuer RD
- Heusse P
- Hill JC
- Hill RD
- Hirschfelder J
- Hodgson PN
- Hofer H
- Hoffman J
- Hoffman K
- Holldorfer F
- Holmgren SO
- Holt PJ
- Holzner G
- Homer RJ
- Horvath D
- Hou SR
- Houlden MA
- Howard R
- Hu H
- Hu Y
- Huang X
- Hughes G
- Hultqvist K
- Huntemeyer P
- Hutchcroft DE
- Huttmann K
- Iaselli G
- Igo-Kemenes P
- Ishii K
- Jacholkowska A
- Jackson JN
- Jakobs K
- Janot P
- Jarlskog G
- Jarry P
- Jeans D
- Jeremie H
- Jezequel S
- Jin BN
- Jin S
- Johansson EK
- Johansson PD
- Jones LT
- Jones LW
- Jones RWL
- Jonsson P
- Joram C
- Josa-Mutuberria I
- Jost B
- Jousset J
- Jovanovic P
- Jungermann L
- Junk TR
- Kachelhoffer T
- Kado M
- Kafer D
- Kanaya N
- Kanzaki J
- Kapusta F
- Karapetian G
- Karlen D
- Kartvelishvili V
- Katsanevas S
- Katsoufis E
- Kaur M
- Kawagoe K
- Kawamoto T
- Kayser F
- Keeler RK
- Kellogg RG
- Kennedy BW
- Kennedy J
- Kernel G
- Kersevan BP
- Kienzle-Focacci MN
- Kiiskinen A
- Kile J
- Kim DH
- Kim JK
- King BT
- Kirkby J
- Kittel W
- Kjaer NJ
- Klein K
- Kleinknecht K
- Klier A
- Klimentov A
- Kluge EE
- Kluit P
- Kluth S
- Kneringer E
- Kobayashi T
- Kobel M
- Kokkinias P
- Komamiya S
- Konig AC
- Konstantinidis N
- Kopal M
- Kormos L
- Kourkoumelis C
- Koutsenko V
- Kouznetsov O
- Kowalewski RV
- Kraber M
- Kraemer RW
- Kramer T
- Krenz W
- Kress T
- Krieger P
- Krop D
- Kruger A
- Kruger K
- Krumstein Z
- Kucharczyk M
- Kuhn D
- Kunin A
- Kupper M
- Kyriakis A
- Lafferty GD
- Laktineh I
- Lamsa J
- Lancon E
- Landi G
- Landsman H
- Lanske D
- Laurelli P
- Layter JG
- Le Coultre P
- Le Goff JM
- Lebeau M
- Lebedev A
- Lebrun P
- Lecomte P
- Lecoq P
- Leder G
- Ledroit F
- Lee HJ
- Lees JP
- Lehto M
- Leibenguth G
- Leinonen L
- Leins A
- Leiste R
- Leitner R
- Lellouch D
- Lemaire MC
- Lemaitre V
- Lemonne J
- Lepeltier V
- Leroy O
- Lesiak T
- Letts J
- Levinson L
- Levtchenko P
- Li C
- Liebig W
- Ligabue F
- Likhoded S
- Liko D
- Lillich J
- Lin CH
- Lin J
- Lin WT
- Linde FL
- Lipniacka A
- Lista L
- Litke AM
- Liu ZA
- Lloyd SL
- Locci E
- Loebinger FK
- Lohmann W
- Longo E
- Loomis C
- Lopes JH
- Lopez J
- Lopez JM
- Loukas D
- Lu J
- Lu YS
- Lubelsmeyer K
- Luci C
- Luckey D
- Ludwig J
- Luminari L
- Lustermann W
- Lutjens G
- Lutz P
- Lynch JG
- Lyons L
- Ma WG
- Machefert F
- MacNaughton J
- Macpherson A
- Mader W
- Maggi G
- Maggi M
- Malek A
- Maley P
- Malgeri L
- Malinin A
- Maltezos S
- Mana C
- Mandl F
- Mangeol D
- Manner W
- Mannert C
- Mannocchi G
- Mans J
- Marcellini S
- Marchant TE
- Marco J
- Marco R
- Marechal B
- Margoni M
- Marin JC
- Marinelli N
- Mariotti C
- Markou A
- Markou C
- Martin AJ
- Martin F
- Martin JP
- Martin JP
- Martinez M
- Martinez-Rivero C
- Marzano F
- Masetti G
- Mashimo T
- Masik J
- Mastroyiannopoulos N
- Mato P
- Matorras F
- Matteuzzi C
- Mattig P
- Mazumdar K
- Mazzucato F
- Mazzucato M
- Mc Nulty R
- McDonald WJ
- McKenna J
- McMahon TJ
- McNamara PA
- McNeil RR
- McPherson RA
- Medcalf T
- Meijers F
- Mele S
- Mendez-Lorenzo P
- Menges W
- Merino G
- Merle E
- Merola L
- Meroni C
- Merritt FS
- Mes H
- Meschini M
- Messineo A
- Metzger WJ
- Meyer WT
- Michel B
- Michelini A
- Migliore E
- Mihara S
- Mihul A
- Mikenberg G
- Milcent H
- Miller DJ
- Minard MN
- Miquel R
- Mir LM
- Mirabelli G
- Misiejuk A
- Mitaroff W
- Mjoernmark U
- Mnich J
- Moa T
- Moch M
- Moed S
- Moenig K
- Mohanty GB
- Mohr W
- Monge R
- Monteil S
- Montenegro J
- Moraes D
- Moreno S
- Morettini P
- Mori T
- Moser HG
- Moutoussi A
- Muanza GS
- Mueller U
- Muenich K
- Muijs AJM
- Mulders M
- Muller AS
- Mundim L
- Murray W
- Murtas F
- Murtas GP
- Muryn B
- Musicar B
- Musy M
- Mutter A
- Myatt G
- Myklebust T
- Nagai K
- Nagy S
- Nakamura I
- Napolitano M
- Nassiakou M
- Navarria F
- Nawrocki K
- Neal HA
- Negus P
- Nessi-Tedaldi F
- Newman H
- Ngac A
- Nicolaidou R
- Nielsen J
- Niessen T
- Nikolenko M
- Nilsson BS
- Nisati A
- Nisius R
- Norton PR
- Nowak H
- Nowell J
- Nuzzo S
- O'Neale SW
- O'Shea V
- Oblakowska-Mucha A
- Obraztsov V
- Ofierzynski R
- Oh A
- Okpara A
- Olshevski A
- Onofre A
- Orava R
- Oreglia MJ
- Organtini G
- Orito S
- Osterberg K
- Ouraou A
- Oyanguren A
- Pacheco A
- Paganoni M
- Pahl C
- Paiano S
- Palacios JP
- Palka H
- Palla F
- Pallin D
- Palomares C
- Pan YB
- Pandoulas D
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- Zobernig G
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- Zupan M
- Publication venue
- ELSEVIER SCIENCE BV
- Publication date
- 17/07/2003
- Field of study
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
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- Yilmaz Y
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- Yumiceva F
- Yun JC
- Zabel J
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- Zalewski P
- Zanetti M
- Zang J
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- Zoeller MH
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
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- Abbiendi G
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- Weng Y
- Wenger EA
- Werner JS
- West C
- Wetzel J
- Whitbeck A
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- Wickramage N
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- Wissing C
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- Woehri HK
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- Won S
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- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
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- Cipriano PMR
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- Sfiligoi I
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- Sheldon P
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- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
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- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
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- Zhukov V
- Zhukova V
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- Zoeller MH
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- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
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- Abbiendi G
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- Abdullin S
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- Pozzobon N
- Prado Da Silva WL
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- Qian SJ
- Quan X
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- Razis PA
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- Rinkevicius A
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- Rizzi A
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- Rodozov M
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- Schott G
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- Shoaib M
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- Vinogradov A
- Virdee T
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- Vogel H
- Volkov A
- Volobouev I
- Volodko A
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- Vorobyev A
- Vorobyev A
- Voutilainen M
- Vuosalo C
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- Wagner P
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- Wakefield S
- Wallny R
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- Waltenberger W
- Walzel G
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- Wardle N
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- Wayand S
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- Wehrli L
- Weiler T
- Weinberg M
- Wendland L
- Weng Y
- Wenger EA
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- West C
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- Whitbeck A
- Whitmore J
- Whyntie T
- Wickramage N
- Widl E
- Wilken R
- Wilkinson R
- Williams G
- Williams T
- Willmott C
- Wimpenny S
- Winer BL
- Winn D
- Winstrom L
- Wissing C
- Wittich P
- Wittmer B
- Woehri HK
- Wolf M
- Wolf R
- Womersley WJ
- Won S
- Wood D
- Wood J
- Wood JS
- Worm SD
- Wright D
- Wrochna G
- Wu W
- Wuerthwein F
- Wulz C-E
- Wyslouch B
- Xiao H
- Xie S
- Xu M
- Yagil A
- Yalvac M
- Yang F
- Yang M
- Yang Y
- Yang ZC
- Yazgan E
- Yelton J
- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
- …