27 research outputs found

    Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

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    PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Elective cancer surgery in COVID-19-free surgical pathways during the SARS-CoV-2 pandemic: An international, multicenter, comparative cohort study

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    PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19–free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19–free surgical pathways. Patients who underwent surgery within COVID-19–free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19–free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score–matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19–free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION Within available resources, dedicated COVID-19–free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Notas sobre la interpretaci\uf3n en los servicios p\ufablicos de salud en Castilla y Le\uf3n

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    L'articolo presenta il gruppo di ricerca su materiali per l'interpretazione sociale composto dalle Universit\ue0 di Salamanca-Forl\uec-Hildesheim e lo studio da questo realizzato per la Comunidad de Castilla y Le\uf3n con riflessioni sulle nuove coordinate demografiche, linguistiche e culturali della Spagna

    Materiales didåcticos para la enseñanza de la interpretación en el åmbito social (alemån-francés-inglés-italiano-español)

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    Il prodotto si compone di una breve pubblicazione e di un CD. La pubblicazione illustra i materiali contenuti nel CD che consistono in testi didattici di accompagnamento alle videoregistrazioni di dialoghi mediati dall'interprete, con trascrizioni delle stesse, per far esercitare gli studenti di interpretazione su specifici problemi terminologici e di prassi professioanale in una pluralitĂ  di ambiti specialistici

    Comparing the accuracies of remote sensing global burned area products using stratified random sampling and estimation

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    The accuracies of six global burned area (BA) products for year 2008 were compared using the same validation methods and reference data to quantify accuracy of each product. The selected products include MCD64, MCD45 and Geoland2, and three products developed within the Fire Disturbance project (fire_cci), which is part of the European Space Agency's (ESA) Climate Change Initiative (CCI) program. The latter three products were derived from MERIS and VEGETATION sensors (one product from each sensor separately, and a third one from the merging of MERIS and VGT products). The reference fire perimeters were mapped from two multi-temporal Landsat TM/ETM + images at 103 non-overlapping Thiessen scene areas (TSA) selected with a stratified random sampling design. The validation results were based on cross tabulated error matrices from which six accuracy measures were computed following the requirements of end-users of burned area products. While overall accuracy (OA) exceeded 99% for all products, overall accuracy was lower for the burned class. Burned area commission error ratio was above 40% for all products and omission error ratio was above 65% for all products. The statistical significance of differences in accuracy between pairs of products was evaluated based on theory of the stratified combined ratio estimator. Statistical tests identified the MCD64 as the most accurate product, followed by MCD45 and the MERIS product

    Polarographic Assay Based on Hydrogen Peroxide Scavenging in Determination of Antioxidant Activity of Strong Alcohol Beverages

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    Total antioxidant (AO) activity of strong alcohol beverages such as wine and plum brandies, whiskeys, herbal and sweet fruit liqueurs have been assessed using a polarographic assay based on hydrogen peroxide scavenging (HPS). Rank of order of total AO activity, expressed as percentage of decrease of anodic oxidation current of hydrogen peroxide, was found analogous with total phenolic content estimated by Folin Ciocalteau (FC) assay and radical scavenging capacity against the stable free radical 1,1-dipheny1-2-picrylhydrazyl (DPPH). Application of the assay for surveying of a quarter century long maturation of plum brandy in oak barrel was demonstrated. In addition, influence of different storage conditions on preservation of AO activity of some herbal liqueurs was surveyed. Wide area of application of this simple, fast, low cost and reliable assay in analysis and quality monitoring of various strong alcohol beverages was confirmed
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