667 research outputs found
From Starburst to Quiescence: Testing AGN feedback in Rapidly Quenching Post-Starburst Galaxies
Post-starbursts are galaxies in transition from the blue cloud to the red
sequence. Although they are rare today, integrated over time they may be an
important pathway to the red sequence. This work uses SDSS, GALEX, and WISE
observations to identify the evolutionary sequence from starbursts to fully
quenched post-starbursts in the narrow mass range , and identifies "transiting" post-starbursts which are intermediate
between these two populations. In this mass range, of galaxies are
starbursts, are quenched post-starbursts, and are the
transiting types in between. The transiting post-starbursts have stellar
properties that are predicted for fast-quenching starbursts and morphological
characteristics that are already typical of early-type galaxies. The AGN
fraction, as estimated from optical line ratios, of these post-starbursts is
about 3 times higher () than that of normal star-forming
galaxies of the same mass, but there is a significant delay between the
starburst phase and the peak of nuclear optical AGN activity (median age
difference of Myr), in agreement with previous studies.
The time delay is inferred by comparing the broad-band near NUV-to-optical
photometry with stellar population synthesis models. We also find that
starbursts and post-starbursts are significantly more dust-obscured than normal
star-forming galaxies in the same mass range. About of the starbursts
and of the transiting post-starbursts can be classified as the
"Dust-Obscured Galaxies" (DOGs), while only of normal galaxies are
DOGs.The time delay between the starburst phase and AGN activity suggests that
AGN do not play a primary role in the original quenching of starbursts but may
be responsible for quenching later low-level star formation during the
post-starburst phase.Comment: 30 pages, 18 figures,accepted to Ap
No evidence for feedback: Unexceptional Low-ionization winds in Host galaxies of Low Luminosity Active Galactic Nuclei at Redshift z ~1
We study winds in 12 X-ray AGN host galaxies at z ~ 1. We find, using the
low-ionization Fe II 2586 absorption in the stacked spectra, that the
probability distribution function (PDF) of the centroid velocity shift in AGN
has a median, 16th and 84th percentiles of (-87, -251, +86) km/s respectively.
The PDF of the velocity dispersion in AGN has a median, 84th and 16th
percentile of (139, 253, 52) km/s respectively. The centroid velocity and the
velocity dispersions are obtained from a two component (ISM+wind) absorption
line model. The equivalent width PDF of the outflow in AGN has median, 84th and
16th percentiles of (0.4, 0.8, 0.1) Angstrom. There is a strong ISM component
in Fe II 2586 absorption with (1.2, 1.5, 0.8) Angstrom, implying presence of
substantial amount cold gas in the host galaxies. For comparison, star-forming
and X-ray undetected galaxies at a similar redshift, matched roughly in stellar
mass and galaxy inclination, have a centroid velocity PDF with percentiles of
(-74, -258, +90) km/s, and a velocity dispersion PDF percentiles of (150, 259,
57) km/s. Thus, winds in the AGN are similar to star-formation-driven winds,
and are too weak to escape and expel substantial cool gas from galaxies. Our
sample doubles the previous sample of AGN studied at z ~ 0.5 and extends the
analysis to z ~ 1. A joint reanalysis of the z ~ 0.5 AGN sample and our sample
yields consistent results to the measurements above.Comment: 24 pages, 11 figures, accepted in Ap
Isolated tricuspid valve infective endocarditis - A report of 6 cases
Six cases of isolated tricuspid valve endocarditis in young women are described. Preceding genital sepsis was a predisposing factor in 4 patients. Cardiac signs are unusual at presentation, rendering the diagnosis difficult. Pleuropulmonary manifestations are the predominant findings, while overt signs of tricuspid insufficiency and right heart failure occur late in the disease. Staphylococcus aureus is the pathogen most commonly found and requires energetic treatment for a minimum of 4 weeks. The value of echocardiography in establishing an early diagnosis is stressed. Persistent sepsis constitutes a major indication for surgery.S Afr Med J 1990; 78: 34-3
The Bursty Star Formation Histories of Low-mass Galaxies at Revealed by Star Formation Rates Measured from H and FUV
We investigate the burstiness of star formation histories (SFHs) of galaxies
at by using the ratio of star formation rates (SFRs) measured from
H and FUV (1500 \AA) (H--to--FUV ratio). Our sample contains 164
galaxies down to stellar mass (M*) of in the CANDELS GOODS-N
region, where Team Keck Redshift Survey DEIMOS spectroscopy and HST/WFC3 F275W
images from CANDELS and Hubble Deep UV Legacy Survey are available. When the
{\it ratio} of H- and FUV-derived SFRs is measured, dust extinction
correction is negligible (except for very dusty galaxies) with the Calzetti
attenuation curve. The H--to--FUV ratio of our sample increases with M*
and SFR. The median ratio is 0.7 at M* (or SFR) and increases to 1 at M* (or SFR
). At M*, our median H--to--FUV
ratio is lower than that of local galaxies at the same M*, implying a redshift
evolution. Bursty SFH on a timescale of a few tens of megayears on galactic
scales provides a plausible explanation of our results, and the importance of
the burstiness increases as M* decreases. Due to sample selection effects, our
H--to--FUV ratio may be an upper limit of the true value of a complete
sample, which strengthens our conclusions. Other models, e.g., non-universal
initial mass function or stochastic star formation on star cluster scales, are
unable to plausibly explain our results.Comment: 13 pages, 8 figures. ApJ accepted. The main conclusions are not
changed. Major modifications include: (1) to be consistent with the
literature, now reporting H\beta--to--FUV ratio (rather than FUV--to--H\beta\
in the first version); (2) detailed discussions on dust extinction
correction; (3) new SF bustiness calculation; and (4) enriched discussions in
Introductio
A CANDELS WFC3 Grism Study of Emission-Line Galaxies at z~2: A Mix of Nuclear Activity and Low-Metallicity Star Formation
We present Hubble Space Telescope Wide Field Camera 3 slitless grism
spectroscopy of 28 emission-line galaxies at z~2, in the GOODS-S region of the
Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS). The
high sensitivity of these grism observations, with 1-sigma detections of
emission lines to f > 2.5x10^{-18} erg/s/cm^2, means that the galaxies in the
sample are typically ~7 times less massive (median M_* = 10^{9.5} M_sun) than
previously studied z~2 emission-line galaxies. Despite their lower mass, the
galaxies have OIII/Hb ratios which are very similar to previously studied z~2
galaxies and much higher than the typical emission-line ratios of local
galaxies. The WFC3 grism allows for unique studies of spatial gradients in
emission lines, and we stack the two-dimensional spectra of the galaxies for
this purpose. In the stacked data the OIII emission line is more spatially
concentrated than the Hb emission line with 98.1 confidence. We additionally
stack the X-ray data (all sources are individually undetected), and find that
the average L(OIII)/L(0.5-10 keV) ratio is intermediate between typical z~0
obscured active galaxies and star-forming galaxies. Together the compactness of
the stacked OIII spatial profile and the stacked X-ray data suggest that at
least some of these low-mass, low-metallicity galaxies harbor weak active
galactic nuclei.Comment: ApJ accepted. 8 pages, 6 figure
Successful treatment of fusarium solani ecthyma gangrenosum in a patient affected by leukocyte adhesion deficiency type 1 with granulocytes transfusions
<p>Abstract</p> <p>Background</p> <p>Ecthyma gangrenosum (EG) manifests as a skin lesion affecting patients suffering extreme neutropenia and is commonly associated with <it>Pseudomonas aeruginosa </it>in immunocompromised patients. Leukocyte adhesion deficiency I (LAD I) which count among primary immunodeficiency syndromes of the innate immunity, is an autosomal recessive disorder characterized in its severe phenotype by a complete defect in CD18 expression on neutrophils, delayed cord separation, chronic skin ulcers mainly due to recurrent bacterial and fungal infections, leucocytosis with high numbers of circulating neutrophils and an accumulation of abnormally low number of neutrophils at sites of infection.</p> <p>Case Presentation</p> <p>We report at our knowledge the first case of a child affected by LAD-1, who experienced during her disease course a multi-bacterial and fungal EG lesion caused by <it>fusarium solani</it>. Despite targeted antibiotics and anti-fungi therapy, the lesion extended for as long as 18 months and only massive granulocytes pockets transfusions in association with G-CSF had the capacity to cure this lesion.</p> <p>Conclusion</p> <p>We propose that granulocytes pockets transfusions will be beneficial to heal EG especially in severely immunocompromised patients.</p
Determination of zearalenone and its metabolites in endometrial cancer by coupled separation techniques
This study presents a selective method of isolation of zearalenone (ZON) and its metabolite, α-zearalenol (α-ZOL), in neoplastically changed human tissue by accelerated solvent and ultrasonic extractions using a mixture of acetonitrile/water (84/16% v/v) as the extraction solvent. Extraction effectiveness was determined through the selection of parameters (composition of the solvent mixture, temperature, pressure, number of cycles) with tissue contamination at the level of nanograms per gram. The produced acetonitrile/water extracts were purified, and analytes were enriched in columns packed with homemade molecularly imprinted polymers. Purified extracts were determined by liquid chromatography (LC) coupled with different detection systems (diode array detection - DAD and mass spectrometry - MS) involving the Ascentis RP-Amide as a stationary phase and gradient elution. The combination of UE-MISPE-LC (ultrasonic extraction - molecularly imprinted solid-phase extraction - liquid chromatography) produced high (R ≈ 95–98%) and repeatable (RSD < 3%) recovery values for ZON and α-ZOL
A CANDELS WFC3 Grism Study of Emission-Line Galaxies at Z approximates 2: A mix of Nuclear Activity and Low-Metallicity Star Formation
We present Hubble Space Telescope Wide Field Camera 3 slitless grism spectroscopy of 28 emission-line galaxies at z approximates 2, in the GOODS-S region of the Cosmic Assembly Near-infrared Deep Extragalactic Legacy Survey (CANDELS). The high sensitivity of these grism observations, with > 5-sigma detections of emission lines to f > 2.5 X 10(exp -18( erg/s/ square cm, means that the galaxies in the sample are typically approximately 7 times less massive (median M(star). = 10(exp 9.5)M(solar)) than previously studied z approximates 2 emission-line galaxies. Despite their lower mass, the galaxies have [O-III]/H-Beta ratios which are very similar to previously studied z approximates 2 galaxies and much higher than the typical emission-line ratios of local galaxies. The WFC3 grism allows for unique studies of spatial gradients in emission lines, and we stack the two-dimensional spectra of the galaxies for this purpose. In the stacked data the [O-III] emission line is more spatially concentrated than the H-Beta emission line with 98.1% confidence. We additionally stack the X-ray data (all sources are individually undetected), and find that the average L(sub [O-III])/L(sub 0.5.10keV) ratio is intermediate between typical z approximates 0 obscured active galaxies and star-forming galaxies. Together the compactness of the stacked [O-III] spatial profile and the stacked X-ray data suggest that at least some of these low-mass, low-metallicity galaxies harbor weak active galactic nuclei
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015
SummaryBackground The Global Burden of Diseases, Injuries, and Risk Factors Study 2015 provides an up-to-date synthesis of the evidence for risk factor exposure and the attributable burden of disease. By providing national and subnational assessments spanning the past 25 years, this study can inform debates on the importance of addressing risks in context. Methods We used the comparative risk assessment framework developed for previous iterations of the Global Burden of Disease Study to estimate attributable deaths, disability-adjusted life-years (DALYs), and trends in exposure by age group, sex, year, and geography for 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks from 1990 to 2015. This study included 388 risk-outcome pairs that met World Cancer Research Fund-defined criteria for convincing or probable evidence. We extracted relative risk and exposure estimates from randomised controlled trials, cohorts, pooled cohorts, household surveys, census data, satellite data, and other sources. We used statistical models to pool data, adjust for bias, and incorporate covariates. We developed a metric that allows comparisons of exposure across risk factors—the summary exposure value. Using the counterfactual scenario of theoretical minimum risk level, we estimated the portion of deaths and DALYs that could be attributed to a given risk. We decomposed trends in attributable burden into contributions from population growth, population age structure, risk exposure, and risk-deleted cause-specific DALY rates. We characterised risk exposure in relation to a Socio-demographic Index (SDI). Findings Between 1990 and 2015, global exposure to unsafe sanitation, household air pollution, childhood underweight, childhood stunting, and smoking each decreased by more than 25%. Global exposure for several occupational risks, high body-mass index (BMI), and drug use increased by more than 25% over the same period. All risks jointly evaluated in 2015 accounted for 57·8% (95% CI 56·6–58·8) of global deaths and 41·2% (39·8–42·8) of DALYs. In 2015, the ten largest contributors to global DALYs among Level 3 risks were high systolic blood pressure (211·8 million [192·7 million to 231·1 million] global DALYs), smoking (148·6 million [134·2 million to 163·1 million]), high fasting plasma glucose (143·1 million [125·1 million to 163·5 million]), high BMI (120·1 million [83·8 million to 158·4 million]), childhood undernutrition (113·3 million [103·9 million to 123·4 million]), ambient particulate matter (103·1 million [90·8 million to 115·1 million]), high total cholesterol (88·7 million [74·6 million to 105·7 million]), household air pollution (85·6 million [66·7 million to 106·1 million]), alcohol use (85·0 million [77·2 million to 93·0 million]), and diets high in sodium (83·0 million [49·3 million to 127·5 million]). From 1990 to 2015, attributable DALYs declined for micronutrient deficiencies, childhood undernutrition, unsafe sanitation and water, and household air pollution; reductions in risk-deleted DALY rates rather than reductions in exposure drove these declines. Rising exposure contributed to notable increases in attributable DALYs from high BMI, high fasting plasma glucose, occupational carcinogens, and drug use. Environmental risks and childhood undernutrition declined steadily with SDI; low physical activity, high BMI, and high fasting plasma glucose increased with SDI. In 119 countries, metabolic risks, such as high BMI and fasting plasma glucose, contributed the most attributable DALYs in 2015. Regionally, smoking still ranked among the leading five risk factors for attributable DALYs in 109 countries; childhood underweight and unsafe sex remained primary drivers of early death and disability in much of sub-Saharan Africa. Interpretation Declines in some key environmental risks have contributed to declines in critical infectious diseases. Some risks appear to be invariant to SDI. Increasing risks, including high BMI, high fasting plasma glucose, drug use, and some occupational exposures, contribute to rising burden from some conditions, but also provide opportunities for intervention. Some highly preventable risks, such as smoking, remain major causes of attributable DALYs, even as exposure is declining. Public policy makers need to pay attention to the risks that are increasingly major contributors to global burden. Funding Bill & Melinda Gates Foundation
- …