NEUDOSE: NEUtron DOSimetry & Exploration - A CubeSat for Dosimetry of Charged and Neutral Particles

Radiation hazard is a major concern for astronauts, especially as we look beyond LEO. We require a method for real-time measurements of both charged and neutral radiation for personal dosimetry. Large uncertainties in current data mostly due to radiation quality and dose-rate effects

Passive Attitude Control to Decrease CubeSatellite Complexity

Attitude control is often a requirement for the optimal functionality of satellite payloads. The McMaster Neutron Dosimetry and Exploration (NEUDOSE) mission aims to measure charged and neutral radiation in Low Earth Orbit. NEUDOSE can detect particles effectively from any direction due to its spherical symmetry, meaning unlike most satellite missions, it does not require attitude control to function. The attitude is still crucial for the mission in order to achieve optimal communication. The NEUDOSE satellite utilizes Ultra High Frequency and Very High Frequency dipole antennas for communication. If the satellite’s attitude lines up in a specific orientation, communication will be hindered due to the nature of the antenna’s radiation pattern. With short access times to the ground station, and relatively small amounts of data being transferred, effective communication is important for the success of the mission. Initially the NEUDOSE mission had an active attitude control system, but with the lack of pointing requirements for the payload’s operation, and a stringent power budget, the active system was removed. A passive magnetic attitude control system was then explored as a solution to optimize communication, without adding much complexity or burden on the power budget

A plant virus protein, NIa-pro, interacts with Indole-3-acetic acid-amido synthetase, whose levels positively correlate with disease severity

Potato virus Y (PVY) is an economically important plant pathogen that reduces the productivity of several host plants. To develop PVY-resistant cultivars, it is essential to identify the plant-PVY interactome and decipher the biological significance of those molecular interactions. We performed a yeast two-hybrid (Y2H) screen of Nicotiana benthamiana cDNA library using PVY-encoded NIa-pro as the bait. The N. benthamiana Indole-3-acetic acid-amido synthetase (IAAS) was identified as an interactor of NIa-pro protein. The interaction was confirmed via targeted Y2H and bimolecular fluorescence complementation (BiFC) assays. NIa-pro interacts with IAAS protein and consequently increasing the stability of IAAS protein. Also, the subcellular localization of both NIa-pro and IAAS protein in the nucleus and cytosol was demonstrated. By converting free IAA (active form) to conjugated IAA (inactive form), IAAS plays a crucial regulatory role in auxin signaling. Transient silencing of IAAS in N. benthamiana plants reduced the PVY-mediated symptom induction and virus accumulation. Conversely, overexpression of IAAS enhanced symptom induction and virus accumulation in infected plants. In addition, the expression of auxin-responsive genes was found to be downregulated during PVY infection. Our findings demonstrate that PVY NIa-pro protein potentially promotes disease development via modulating auxin homeostasis

Design of a Custom Secondary On-Board Computer for the NEUDOSE CubeSat Mission

The NEUtron DOSimetry & Exploration (NEUDOSE) CubeSat is the first small satellite mission from McMaster University. The mission includes two on-board computers (OBCs): a commercial off-the-shelf (COTS) board as the primary OBC, and a custom student-designed board, the secondary on-board computer (SOBC), as a secondary payload to the mission

Architecture and Design of the McMaster NEUDOSE Communication Radio Subsystem

The communication subsystem is responsible for ensuring robust communication between the McMaster NEUDOSE CubeSat and the Ground Station located at McMaster University. This subsystem sends the collected scientific data, system telemetry (health), and telecommand from the onboard instruments using two different communication radio frequencies

A pair production telescope for medium-energy gamma-ray polarimetry

We describe the science motivation and development of a pair production telescope for medium-energy (∼5–200 MeV) gamma-ray polarimetry. Our instrument concept, the Advanced Energetic Pair Telescope (AdEPT), takes advantage of the Three-Dimensional Track Imager, a low-density gaseous time projection chamber, to achieve angular resolution within a factor of two of the pair production kinematics limit (∼0.6° at 70 MeV), continuum sensitivity comparable with the Fermi-LAT front detector (<3 × 10−6 MeV cm−2 s−1 at 70 MeV), and minimum detectable polarization less than 10% for a 10 mCrab source in 106 s.submittedVersionFil: Hunter, Stanley D. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Fil: Bloser, Peter F. University of New Hampshire. Institute for the Study of Earth, Oceans, and Space. Space Science Center; Estados Unidos de América.Fil: Depaola, Gerardo Osvaldo. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina.Fil: Dion, Michael P. Department of Energy. Office of Science. Pacific Northwest National Laboratory; Estados Unidos de América.Fil: DeNolfo, Georgia A. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Fil: Hanu, Andrei. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Fil: Iparraguirre, Lorenzo Marcos. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía y Física; Argentina.Fil: Legere, Jason. University of New Hampshire. Institute for the Study of Earth, Oceans, and Space. Space Science Center; Estados Unidos de América.Fil: Longo, Francesco. Università Degli Studi de Trieste. Dipartimento di fisica; Italia.Fil: McConnell, Mark L. University of New Hampshire. Institute for the Study of Earth, Oceans, and Space. Space Science Center; Estados Unidos de América.Fil: Nowicki, Suzanne F. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Fil: Nowicki, Suzanne F. University of Maryland, Baltimore County. Department of Physics; Estados Unidos de América.Fil: Ryan, James M. University of New Hampshire. Institute for the Study of Earth, Oceans, and Space. Space Science Center; Estados Unidos de América.Fil: Son, Seunghee. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Fil: Son, Seunghee. University of Maryland, Baltimore County. Department of Physics; Estados Unidos de América.Fil: Stecker, Floyd W. National Aeronautics and Space Administration. Goddard Space Flight Center; Estados Unidos de América.Física de Partículas y Campo

DataSheet_1_A plant virus protein, NIa-pro, interacts with Indole-3-acetic acid-amido synthetase, whose levels positively correlate with disease severity.docx

Potato virus Y (PVY) is an economically important plant pathogen that reduces the productivity of several host plants. To develop PVY-resistant cultivars, it is essential to identify the plant-PVY interactome and decipher the biological significance of those molecular interactions. We performed a yeast two-hybrid (Y2H) screen of Nicotiana benthamiana cDNA library using PVY-encoded NIa-pro as the bait. The N. benthamiana Indole-3-acetic acid-amido synthetase (IAAS) was identified as an interactor of NIa-pro protein. The interaction was confirmed via targeted Y2H and bimolecular fluorescence complementation (BiFC) assays. NIa-pro interacts with IAAS protein and consequently increasing the stability of IAAS protein. Also, the subcellular localization of both NIa-pro and IAAS protein in the nucleus and cytosol was demonstrated. By converting free IAA (active form) to conjugated IAA (inactive form), IAAS plays a crucial regulatory role in auxin signaling. Transient silencing of IAAS in N. benthamiana plants reduced the PVY-mediated symptom induction and virus accumulation. Conversely, overexpression of IAAS enhanced symptom induction and virus accumulation in infected plants. In addition, the expression of auxin-responsive genes was found to be downregulated during PVY infection. Our findings demonstrate that PVY NIa-pro protein potentially promotes disease development via modulating auxin homeostasis.</p

Interfacing Geant4, Garfield++ and Degrad for the Simulation of Gaseous Detectors

International audienceFor several years, attempts have been made to interface Geant4 and other software packages with the aim of simulating the complete response of a gaseous particle detector. In such a simulation, Geant4 is always responsible for the primary particle generation and the interactions that occur in the non-gaseous detector material. Garfield++ on the other hand always deals with the drift of ions and electrons, amplification via electron avalanches and finally signal generation. For the ionizing interaction of particles with the gas, different options and physics models exist. The present paper focuses on how to use Geant4, Garfield++ (including its Heed and SRIM interfaces) and Degrad to create the electron–ion pairs stemming from the ionization of the gas. Software-wise, the proposed idea is to use the Geant4 physics parameterization feature, and to implement a Garfield++ or Degrad based detector simulation as an external model. With a Degrad model, detailed simulations of the X-ray interaction in gaseous detectors, including shell absorption by photoelectric effect, subsequent Auger cascade, shake-off and fluorescence emission, become possible. A simple Garfield++ model can be used for photons (Heed), heavy ions (SRIM) and relativistic charged particles or MIPs (Heed). For non-relativistic charged particles, more effort is required, and a combined Geant4/Garfield++ model must be used. This model, the Geant4/Heed PAI model interface, uses the Geant4 PAI model in conjunction with the Heed PAI model. Parameters, such as the lower production cut of the Geant4 PAI model and the lowest electron energy limit of the physics list have to be set correctly. The paper demonstrates how to determine these parameters for certain values of the W parameter and Fano factor of the gas mixture. The simulation results of this Geant4/Heed PAI model interface are then verified against the results obtained with the stand-alone software packages

A Geant4/Garfield++ and Geant4/Degrad Interface for the Simulation of Gaseous Detectors

For several years, attempts have been made to interface Geant4 and other software packages with the aim of simulating the complete response of a gaseous particle detector. The present paper illustrates different possibilities to interface Geant4 with two such packages, Garfield++ and Degrad. The basic idea is to use the Geant4 physics parameterization feature and to implement a Garfield++ or Degrad based detector simulation as an external model. With the Geant4/Degrad interface, detailed simulations of the X-ray interaction in gaseous detectors, including shell absorption by photoelectric effect, subsequent Auger shake-off, and fluorescence emission, become possible. The Geant4/Garfield++ interface can be used for photons and charged particles of all kinetic energies. Depending on the particular physics case, either the Geant4 PAI model, the Heed PAI model or both Geant4 and Heed are responsible for primary ionization and the production of the conduction electrons. For the case in which the Geant4 PAI model is used in conjunction with the Heed PAI model, a more detailed analysis is performed. Parameters, such as the lower production cut of the PAI model and the lowest electron energy limit of the physics list have to be set correctly. The paper demonstrates how to determine these parameters with the help of the W value and Fano factor of the gas mixture. The simulation results of this Geant4/Heed PAI model interface are then verified against the results obtained with the standalone software packages

Interfacing Geant4, Garfield+ plus and Degrad for the simulation of gaseous detectors

© 2019 For several years, attempts have been made to interface Geant4 and other software packages with the aim of simulating the complete response of a gaseous particle detector. In such a simulation, Geant4 is always responsible for the primary particle generation and the interactions that occur in the non-gaseous detector material. Garfield++ on the other hand always deals with the drift of ions and electrons, amplification via electron avalanches and finally signal generation. For the ionizing interaction of particles with the gas, different options and physics models exist. The present paper focuses on how to use Geant4, Garfield++ (including its Heed and SRIM interfaces) and Degrad to create the electron–ion pairs stemming from the ionization of the gas. Software-wise, the proposed idea is to use the Geant4 physics parameterization feature, and to implement a Garfield++ or Degrad based detector simulation as an external model. With a Degrad model, detailed simulations of the X-ray interaction in gaseous detectors, including shell absorption by photoelectric effect, subsequent Auger cascade, shake-off and fluorescence emission, become possible. A simple Garfield++ model can be used for photons (Heed), heavy ions (SRIM) and relativistic charged particles or MIPs (Heed). For non-relativistic charged particles, more effort is required, and a combined Geant4/Garfield++ model must be used. This model, the Geant4/Heed PAI model interface, uses the Geant4 PAI model in conjunction with the Heed PAI model. Parameters, such as the lower production cut of the Geant4 PAI model and the lowest electron energy limit of the physics list have to be set correctly. The paper demonstrates how to determine these parameters for certain values of the W parameter and Fano factor of the gas mixture. The simulation results of this Geant4/Heed PAI model interface are then verified against the results obtained with the stand-alone software packages.keywords: Gaseous detectors, Monte-carlo simulation, Particle interactions, Software engineering, Geant4status: publishe