260 research outputs found
High susceptibility of c-KIT+CD34+ precursors to prolonged doxorubicin exposure interferes with Langerhans cell differentiation in a human cell line model
- Author
- A Blair
- A Curti
- AJ Masterson
- Anneke W. Reurs
- E Khoury
- E Ullrich
- Erik Hooijberg
- G Minckwitz von
- G Minckwitz von
- GD Leonard
- George L. Scheffer
- Gerrit Jansen
- H Andersen
- H Strobl
- H Ueno
- Hetty J. Bontkes
- HJ Bontkes
- HJ Long III
- HJ Long III
- J Bijl
- JP Annereau
- L Apetoh
- L Deville
- L Zitvogel
- M Waele De
- MC Bene
- MW Schreurs
- MW Schreurs
- N Casares
- PJ Snijders
- R Ven van de
- RA Briddell
- Rieneke van de Ven
- Rik J. Scheper
- SC Dowdy
- SJ Santegoets
- SJ Santegoets
- Sue Ellen Verbrugge
- Tanja D. de Gruijl
- TD Gruijl de
- Y Gunji
- ZB Hu
- Publication venue
- Springer-Verlag
- Publication date
- 01/01/2011
- Field of study
As neoadjuvant and adjuvant chemotherapy schedules often consist of multiple treatment cycles over relatively long periods of time, it is important to know what effects protracted drug administration can have on the immune system. Here, we studied the long-term effects of doxorubicin on the capacity of dendritic cell (DC) precursors to differentiate into a particular DC subset, the Langerhans cells (LC). In order to achieve high telomerase activity as detected in hematological stem cells, precursor cells from the acute-myeloid leukemia (AML)-derived cell line MUTZ3 were stably transduced with human telomerase reverse transcriptase (hTERT) to facilitate their growth potential, while preventing growth, and drug-induced senescence, and preserving their unique capacity for cytokine-dependent DC and LC differentiation. The hTERT-MUTZ3 cells were selected with increasing concentrations of the anthracyclin doxorubicin. After 1–2 months of selection with 30–90 nM doxorubicin, the cells completely lost their capacity to differentiate into LC. This inhibition turned out to be reversible, as the cells slowly regained their capacity to differentiate after a 3- to 4-month drug-free period and with this became capable again of priming allogeneic T cells. Of note, the loss and gain of this capacity to differentiate coincided with the loss and gain of a subpopulation within the CD34+ proliferative compartment with surface expression of the stem cell factor receptor (SCF-R/CD117/c-Kit). These data are in favor of cytostatic drug-free intervals before applying autologous DC-based vaccination protocols, as specific DC precursors may need time to recover from protracted chemotherapy treatment and re-emerge among the circulating CD34+ hematopoietic stem and precursor cells
Adjuvant hysterectomy for treatment of residual disease in patients with cervical cancer treated with radiation therapy
- Author
- A Maneo
- AH Russell
- CA Perez
- CM Matthews
- CR Stanhope
- CW Whitney
- DH Moore
- DM Parkin
- E Gerdin
- FN Rutledge
- GM Sommers
- GW Morley
- HH Gallion
- HJ Long III
- HM Keys
- HM Keys
- HM Shingleton
- I Barillot
- JD Cox
- K Hasumi
- K Takizawa
- L Coia
- M Morris
- MS Piver
- N Takeshima
- PG Rose
- PJ Eifel
- R Komaki
- RL Coleman
- S Rutledge
- T Nakano
- T Ota
- T Ota
- T Tabata
- V Moutardier
- W Xiang-E
- WA Peters III
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
The objective of this retrospective study was to determine the efficacy of adjuvant hysterectomy for treatment of residual disease in cervical carcinoma treated with radiation therapy. Between 1971 and 1996, 1590 patients with carcinoma of the uterine cervix (stages I–IIIb) were treated with radiation therapy. Three months after completion of radiation therapy, the status of local control was investigated, and total abdominal hysterectomy was performed in cases in which central residual disease existed in the cervix. Of the 1590 patients, residual disease was identified in 162 patients. Among these patients, 35 showed an absence of distant metastasis or lateral parametrial invasion and underwent hysterectomy. The overall 5- and 10-year survival rates for these patients were 68.6 and 65.7%, respectively. There was no significant difference in survival between patients with squamous cell carcinoma and those with non-squamous cell carcinoma or between patients with stage I/II carcinoma and those with stage III carcinoma. With respect to treatment-related morbidity, five (14.3%) patients suffered grade III or IV complications after hysterectomy. Adjuvant hysterectomy is an effective addition to radiation therapy in the treatment of cervical cancer, even in patients with stage III disease and in those with non-squamous cell carcinoma
Phase I–II study of irinotecan (CPT-11) plus nedaplatin (254-S) with recombinant human granulocyte colony-stimulating factor support in patients with advanced or recurrent cervical cancer
- Author
- AM Murad
- CA Papadimitriou
- CA Papadimitriou
- CF Verschraegen
- EJ Buxton
- F Kanazawa
- F Oshita
- GA Omura
- H Tsuda
- HJ Long III
- K Nitta
- K Ota
- K Ota
- K Sugeno
- K Tobina
- KR Brader
- M Miyama
- M Morris
- M Sekiya
- N Kawamura
- P Bonomi
- PG Rose
- S Machida
- S Nakata
- S Negoro
- S Nishimura
- S Takeuchi
- T Kato
- T Thigpen
- T Thigpen
- T Thigpen
- TG Robert
- WP Ivrin
- WP McGuire
- Y Hashiguchi
- Y Kameyama
- Y Sasaki
- Y Suzumura
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Combination chemotherapy with irinotecan (CPT-11) and platinum compounds is effective for treating cervical cancer. Nedaplatin (254-S) is a new cisplatin analogue that achieves a high response rate (53%) in patients with primary cervical cancer. We performed a phase I–II study of combination chemotherapy with CPT-11 plus 254-S for advanced or recurrent cervical cancer. The inclusion criteria were stage IV disease or recurrence. CPT-11 and 254-S were administered intravenously on day 1, while rhG-CSF (50 μg) was given on days 3–12. This regimen was repeated after 4 weeks. Dose escalation was carried out in tandem (CPT-11/254-S: 50/70, 50/80, and 60/80 mg m−2). A total of 27 patients (stage IV=seven, recurrence=20) were enrolled. The phase I study enrolled eight patients. At dose levels 1 and 2, no dose-limiting toxicities were observed. At dose level 3, the first two patients developed DLTs. The maximum tolerated dose of CPT-11 and 254-S was 60 and 80 mg m−2, respectively, and the recommended doses were 50 and 80 mg m−2. Grade 3/4 haematologic toxicity occurred in 67% in phase II study, but there were no grade 3 nonhaematologic toxicities except fot nausea or lethargy. In all 27 patients, there were two complete responses (7%) and 14 Partial responses (52%), for an overall response rate of 59% (95% confidence interval: 39–78%). Among the 12 responders with recurrent disease, the median time to progression and median survival were 161 days (range: 61–711 days) and 415 days (range: 74–801 days). This new regimen is promising for cervical cancer
Evaluation of the paclitaxel–ifosfamide–cisplatin (TIP) combination in relapsed and/or metastatic cervical cancer
- Author
- A Buda
- A Karabelis
- A Lissoni
- AA Lissoni
- AP Kudelka
- BJ Monk
- C Kosmas
- C Kosmas
- C Kosmas
- C Kosmas
- CA Bunnell
- CA Papadimitriou
- CH Choi
- DH Moore
- DR Cox
- E Reed
- EA Eisenhauer
- EK Rowinsky
- EL Kaplan
- G Tsakonas
- G Vorgias
- G Zanetta
- G Zanetta
- GA Omura
- GP Sutton
- HJ Long III
- J Herod
- JC Cervellino
- JE Liebmann
- MA Dimopoulos
- MJ Lind
- N Kalinoglou
- N Karvounis
- N Malamos
- N Mylonakis
- N Tsavaris
- N Tsavaris
- PG Rose
- R Simon
- RJ Parker
- T Akrivos
- T Daladimos
- T Thigpen
- WP McGuire
- Publication venue
- Nature Publishing Group
- Publication date
- Field of study
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
- Akgun U
- Akin IV
- Alagoz E
- Albajar C
- Albayrak EA
- Albergo S
- Albrow M
- Alda Junior WL
- Alexander J
- Aliev T
- Almeida N
- Alver B
- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunes JR
- Antunovic Z
- Apanasevich L
- Apollinari G
- Appelt E
- Apresyan A
- Aranyi A
- Arce P
- Arcidiacono R
- Arenton MW
- Arfaei H
- Argiro S
- Arisaka K
- Arneodo M
- Arora S
- Asawatangtrakuldee C
- Asghar MI
- Askew A
- Assran Y
- Ata M
- Atac M
- Atramentov O
- Attikis A
- Auffray E
- Autermann C
- Auzinger G
- Avdeeva E
- Avery P
- Avetisyan A
- Azarkin M
- Azhgirey I
- Aziz T
- Azzi P
- Azzolini V
- Azzurri P
- Baarmand MM
- Babb J
- Bacchetta N
- Bachtis M
- Baden A
- Baeni L
- Baesso P
- Baffioni S
- Bagliesi G
- Bai Y
- Baillon P
- Bainbridge R
- Bakhshiansohi H
- Bakirci MN
- Bakken JA
- Balazs M
- Ball AH
- Ball G
- Ban Y
- Banerjee S
- Banerjee S
- Bansal S
- Banzuzi K
- Barbagli G
- Barberis E
- Barbone L
- Bardak C
- Barfuss AF
- Bargassa P
- Barge D
- Baringer P
- Barker A
- Barnes VE
- Barnett BA
- Barney D
- Barone L
- Barrett M
- Bartalini P
- Barth C
- Basegmez S
- Basso L
- Battilana C
- Baty C
- Bauer G
- Bauerdick LAT
- Baumgartel D
- Baur U
- Bayshev I
- Bazterra VE
- Bean A
- Beauceron S
- Beaudette F
- Beaupere N
- Bedjidian M
- Beernaert K
- Behrenhoff W
- Behrens U
- Belforte S
- Beliy N
- Belknap D
- Bell AJ
- Bell KW
- Bellan P
- Bellan R
- Bellato M
- Bellinger JN
- Belotelov I
- Belyaev A
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- Benaglia A
- Bencze G
- Bendavid J
- Benedetti D
- Benelli G
- Benhabib L
- Beni N
- Benucci L
- Benussi L
- Benvenuti AC
- Beranek S
- Beretvas A
- Bergauer T
- Berger J
- Bergholz M
- Beri SB
- Bernardes CA
- Bernardini J
- Bernet C
- Berry D
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- Berryhill J
- Bertl W
- Berzano U
- Besancon M
- Betchart B
- Bethani A
- Betts RR
- Beuselinck R
- Bhat PC
- Bhatnagar V
- Bhattacharya S
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- Bhatti A
- Bialas W
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- Bian JG
- Bianchi G
- Bianchini L
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- Biino C
- Bilei GM
- Bilin B
- Bilinskas MJ
- Bilki B
- Bilmis S
- Biselli A
- Bisello D
- Bitioukov S
- Blekman F
- Blobel V
- Bloch D
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- Bloom K
- Bluj M
- Blumenfeld B
- Blyweert S
- Bobrovskyi S
- Boccali T
- Bocci A
- Bochenek J
- Bodek A
- Bodin D
- Boimska B
- Boldizsar L
- Bolla G
- Bolognesi S
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- Bonacorsi D
- Bonato A
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- Bontenackels M
- Boos E
- Bornheim A
- Borras K
- Borrello L
- Bortignon P
- Bortoletto D
- Bose S
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- Bostock F
- Botta C
- Boudoul G
- Boulahouache C
- Boumediene D
- Bourilkov D
- Boutemeur M
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- Braibant-Giacomelli S
- Branca A
- Branson JG
- Breedon R
- Breto G
- Breuker H
- Brew C
- Brigliadori L
- Brigljevic V
- Brinkerhoff A
- Broccolo G
- Brochero Cifuentes JA
- Brom JM
- Brona G
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- Brown RM
- Brownson E
- Brun H
- Bruno G
- Bryer AG
- Buchmann MA
- Buchmuller O
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- Burgmeier A
- Burkett K
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- Busza W
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- Cabrera A
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- Caebergs T
- Cakir A
- Calabria C
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- Calderon A
- Cali IA
- Calligaris L
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- Calvert B
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- Campagnari C
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- Capiluppi P
- Caponeri B
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- Carlsmith D
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- Carvalho W
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- Casimiro Linares E
- Castaldi R
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- Caulfield M
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- Cepeda M
- Cerati GB
- Cerci DS
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- Chamizo Llatas M
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- Chang S
- Chang YH
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- Chatrchyan S
- Chatterjee A
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- Cherepanov V
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- Chhibra SS
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- Chiochia V
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- Choudhury RK
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- Cimmino A
- Cipriano PMR
- Cirino G
- Cittolin S
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- Civinini C
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- Clarida W
- Clement E
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- CMS Collaboration
- Cockerill DJA
- Codispoti G
- Colafranceschi S
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- Cortezon EP
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- Cuplov V
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- Custodio A
- Cutajar M
- Cutts D
- Cwiok M
- Czellar S
- D'Agnolo RT
- D'Alessandro R
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- D'Enterria D
- D'Hondt J
- Da Costa EM
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- Dallavalle GM
- Damgov J
- Damiao DD
- Dammann D
- Danielson T
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- Daskalakis G
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- Daubie E
- Dauncey P
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- De Benedetti A
- De Boer W
- de Cassagnac RG
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- de Fatis TT
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- De Gruttola M
- De Guio F
- De Jeneret JD
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- De Mattia M
- de Monchenault GH
- De Oliveira Martins C
- De Palma M
- De Roeck A
- de Troconiz JF
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- De Wolf EA
- Deisher A
- Deiters K
- Dejardin M
- del Arbol PMR
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- Delaere C
- Delgado Peris A
- Deliomeroglu M
- Dell'Orso R
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- Demaria N
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- Demortier L
- Denegri D
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- Dermenev A
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- Gonzalez Caballero I
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- Gouzevitch M
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- Gramenitski I
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- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
- Yoon AS
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- Yumiceva F
- Yun JC
- Zabel J
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- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
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- Ziebarth EB
- Ziegler J
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- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Performance of CMS muon reconstruction in pp collision events at sqrt(s) = 7 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
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- Acosta MV
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- Yoo J
- Yoon AS
- York A
- Yu I
- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
- Zang SL
- Zarubin A
- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zoeller MH
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'IOP Publishing'
- Publication date
- 01/01/2012
- Field of study
The performance of muon reconstruction, identification, and triggering in CMS
has been studied using 40 inverse picobarns of data collected in pp collisions
at sqrt(s) = 7 TeV at the LHC in 2010. A few benchmark sets of selection
criteria covering a wide range of physics analysis needs have been examined.
For all considered selections, the efficiency to reconstruct and identify a
muon with a transverse momentum pT larger than a few GeV is above 95% over the
whole region of pseudorapidity covered by the CMS muon system, abs(eta) < 2.4,
while the probability to misidentify a hadron as a muon is well below 1%. The
efficiency to trigger on single muons with pT above a few GeV is higher than
90% over the full eta range, and typically substantially better. The overall
momentum scale is measured to a precision of 0.2% with muons from Z decays. The
transverse momentum resolution varies from 1% to 6% depending on pseudorapidity
for muons with pT below 100 GeV and, using cosmic rays, it is shown to be
better than 10% in the central region up to pT = 1 TeV. Observed distributions
of all quantities are well reproduced by the Monte Carlo simulation.Comment: Replaced with published version. Added journal reference and DO
Azimuthal anisotropy of charged particles at high transverse momenta in PbPb collisions at sqrt(s[NN]) = 2.76 TeV
- Author
- Abbaneo D
- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
- Acosta D
- Acosta JG
- Acosta MV
- Adair A
- Adam N
- Adam W
- Adams MR
- Adams T
- Adiguzel A
- Adler V
- Adzic P
- Afanasiev S
- Agostino L
- Agram JL
- Aguilar-Benitez M
- Aguilo E
- Ahmad M
- Ahmad WH
- Ahuja S
- Akchurin N
- Akgun B
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- Akin IV
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- Alcaraz Maestre J
- Alda Junior WL
- Alexander J
- Aliev T
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- Alverson G
- Alves GA
- Amapane N
- Amsler C
- Anagnostou G
- Anastassov A
- Anderson J
- Anderson M
- Andrea J
- Andreev V
- Andreev V
- Andreev Y
- Andrews W
- Anghel IM
- Anjos TS
- Antonelli L
- Antunovic Z
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- Chang YH
- Chang YW
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- Ciulli V
- Civinini C
- Claes DR
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- Clarida W
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- Clerbaux B
- Cline D
- CMS Collaboration
- Coarasa Perez JA
- Cockerill DJA
- Codispoti G
- Colafranceschi S
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- Cuplov V
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- Vorobyev A
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- Wissing C
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- Yi K
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- Yilmaz Y
- Yohay R
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- Yu SS
- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
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- Zatserklyaniy A
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- Zhukov V
- Zhukova V
- Ziebarth EB
- Ziegler J
- Zielinski M
- Zito G
- Zotto P
- Zou W
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
The azimuthal anisotropy of charged particles in PbPb collisions at
nucleon-nucleon center-of-mass energy of 2.76 TeV is measured with the CMS
detector at the LHC over an extended transverse momentum (pt) range up to
approximately 60 GeV. The data cover both the low-pt region associated with
hydrodynamic flow phenomena and the high-pt region where the anisotropies may
reflect the path-length dependence of parton energy loss in the created medium.
The anisotropy parameter (v2) of the particles is extracted by correlating
charged tracks with respect to the event-plane reconstructed by using the
energy deposited in forward-angle calorimeters. For the six bins of collision
centrality studied, spanning the range of 0-60% most-central events, the
observed v2 values are found to first increase with pt, reaching a maximum
around pt = 3 GeV, and then to gradually decrease to almost zero, with the
decline persisting up to at least pt = 40 GeV over the full centrality range
measured.Comment: Replaced with published version. Added journal reference and DO
Gynecologic oncology group trials of chemotherapy for metastatic and recurrent cervical cancer
- Author
- A Jemal
- A Jemal
- AD Tiersten
- AP Kudelka
- AP Kudelka
- BJ Gitlitz
- BJ Monk
- BP Schneider
- Bradley J. Monk
- C Lhommé
- CA Papadimitriou
- CW Whitney
- D Pouessel
- DH Johnson
- DH Moore
- DK Armstrong
- DS Alberts
- E Raymond
- EJ Buxton
- FA Shepherd
- FB Stehman
- FM Muggia
- FN Muggia
- G Colucci
- G Zanetta
- GA Omura
- GF Fleming
- GJ Peters
- GP Sutton
- GP Sutton
- GS Akerman
- HB Muss
- HD Homeseley
- HJ Long III
- HJ Long III
- HJ Wallace Jr
- HM Keys
- HY Lim
- J Arseneau
- J Fiorica
- J Villella
- JA Roberts
- JC Luo
- JD Bloss
- JH Malfetano
- JH Malfetano
- JK Wolf
- JL Benedet
- JP Curtin
- JT Thigpen
- JT Thigpen
- JW Kim
- KJ Kim
- Krishnansu S. Tewari
- KS Tewari
- KY Look
- KY Look
- LG Feun
- LI Muderspach
- LR Bigler
- M Morris
- M Morris
- M Ng
- MA Bookman
- MA Dimopoulos
- ML Hensley
- P Boabang
- P Bonomi
- P Bonomi
- PG Rose
- PG Rose
- PG Rose
- PG Rose
- PG Rose
- PM Fracasso
- RA Cooper
- RJ Schilder
- RS Mannel
- S Lincoln
- S Pignata
- SC Plaxe
- SC Plaxe
- SS Im
- T Thigpen
- W Plunkett
- WA Peters III
- WP McGuire
- WP McGuire
- WP McGuire III
- Z Fan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/11/2005
- Field of study
Because only 16% of patients with metastatic cervical cancer are alive 5 years after diagnosis, the Gynecologic Oncology Group (GOG) has carefully designed and conducted many phase II studies to identify promising drugs. Cisplatin has emerged as the most active single agent with overall response rates of 19%. Recent phase III trials have documented response rates of 27% and 39% when cisplatin has been combined with either paclitaxel or topotecan, respectively. The comparison of cisplatin to cisplatin plus topotecan in GOG-179 has yielded the first study to show a statistically significant impact on the overall response rate, median progression-free survival, and median survival, with all outcome measures favoring the two-drug regimen. Despite these encouraging results, however, most of the responses are partial and of short duration. The need for novel combinations and the implementation of active biologic agents is implicit. The accumulated data in this disease setting, as evidenced by the experience of the GOG, are presented in this review
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy
- Author
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- Abbiendi G
- Abbrescia M
- Abdullin S
- Abdulsalam A
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- Acosta JG
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- Yang M
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- Yetkin T
- Yi K
- Yildirim E
- Yilmaz Y
- Yohay R
- Yoo HD
- Yoo J
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- Yumiceva F
- Yun JC
- Zabel J
- Zabi A
- Zablocki J
- Zaganidis N
- Zakaria M
- Zalewski P
- Zanetti M
- Zang J
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- Zatserklyaniy A
- Zeinali M
- Zeise M
- Zeuner WD
- Zeyrek M
- Zhang J
- Zhang Z
- Zheng Y
- Zhokin A
- Zhu B
- Zhu RY
- Zhukov V
- Zhukova V
- Zielinski M
- Zito G
- Zou W
- Zucchetta A
- Zumerle G
- Zuranski A
- Publication venue
- 'American Physical Society (APS)'
- Publication date
- 01/01/2012
- Field of study
A search for new physics is performed in events with two same-sign isolated
leptons, hadronic jets, and missing transverse energy in the final state. The
analysis is based on a data sample corresponding to an integrated luminosity of
4.98 inverse femtobarns produced in pp collisions at a center-of-mass energy of
7 TeV collected by the CMS experiment at the LHC. This constitutes a factor of
140 increase in integrated luminosity over previously published results. The
observed yields agree with the standard model predictions and thus no evidence
for new physics is found. The observations are used to set upper limits on
possible new physics contributions and to constrain supersymmetric models. To
facilitate the interpretation of the data in a broader range of new physics
scenarios, information on the event selection, detector response, and
efficiencies is provided.Comment: Published in Physical Review Letter
Measurement of the Z/gamma* + b-jet cross section in pp collisions at 7 TeV
- Author
- Abbaneo D.
- Abbiendi G.
- Abbrescia M.
- Abdullin S.
- Acosta D.
- Acosta J. G.
- Acosta M. Vazquez
- Adair A.
- Adam N.
- Adam W.
- Adams M. R.
- Adams T.
- Adiguzel A.
- Adler V.
- Adzic P.
- Afanasiev S.
- Agostino L.
- Agram J-L
- Aguilar-Benitez M.
- Aguilo E.
- Ahmad M.
- Ahmad W. Haj
- Ahuja S.
- Akchurin N.
- Akgun B.
- Akgun U.
- Akin I. V.
- Alagoz E.
- Albajar C.
- Albayrak E. A.
- Albergo S.
- Albrow M.
- Alcaraz Maestre J.
- Alda Junior W. L.
- Alexander J.
- Aliev T.
- Almeida N.
- Alver B.
- Alverson G.
- Alves G. A.
- Amapane N.
- Amsler C.
- Anagnostou G.
- Anastassov A.
- Anderson J.
- Anderson M.
- Andrea J.
- Andreev V.
- Andreev V.
- Andreev Yu.
- Andrews W.
- Anghel I. M.
- Anjos T. S.
- Antonelli L.
- Antunes J. Rodrigues
- Antunovic Z.
- Apanasevich L.
- Apollinari G.
- Appelt E.
- Apresyan A.
- Aranyi A.
- Arce P.
- Arcidiacono R.
- Arenton M. W.
- Arfaei H.
- Argiro S.
- Arisaka K.
- Arneodo M.
- Arora S.
- Asawatangtrakuldee C.
- Asghar M. I.
- Askew A.
- Assran Y.
- Ata M.
- Atac M.
- Atramentov O.
- Attikis A.
- Auffray E.
- Autermann C.
- Auzinger G.
- Avdeeva E.
- Avery P.
- Avetisyan A.
- Azarkin M.
- Azhgirey I.
- Aziz T.
- Azzi P.
- Azzolini V.
- Azzurri P.
- Baarmand M. M.
- Babb J.
- Bacchetta N.
- Bachtis M.
- Baden A.
- Baeni L.
- Baesso P.
- Baffioni S.
- Bagliesi G.
- Bai Y.
- Baillon P.
- Bainbridge R.
- Bakhshiansohi H.
- Bakirci M. N.
- Bakken J. A.
- Balazs M.
- Ball A. H.
- Ball G.
- Ban Y.
- Banerjee S.
- Banerjee S.
- Bansal S.
- Banzuzi K.
- Barbagli G.
- Barberis E.
- Barbone L.
- Bardak C.
- Barfuss A. F.
- Bargassa P.
- Barge D.
- Baringer P.
- Barker A.
- Barnes V. E.
- Barnett B. A.
- Barney D.
- Barone L.
- Barrett M.
- Bartalini P.
- Barth C.
- Basegmez S.
- Basso L.
- Battilana C.
- Baty C.
- Bauer G.
- Bauerdick L. A. T.
- Baumgartel D.
- Baur U.
- Bayshev I.
- Bazterra V. E.
- Bean A.
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- Xiao H.
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- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2012
- Field of study
The production of b jets in association with a Z/gamma* boson is studied
using proton-proton collisions delivered by the LHC at a centre-of-mass energy
of 7 TeV and recorded by the CMS detector. The inclusive cross section for
Z/gamma* + b-jet production is measured in a sample corresponding to an
integrated luminosity of 2.2 inverse femtobarns. The Z/gamma* + b-jet cross
section with Z/gamma* to ll (where ll = ee or mu mu) for events with the
invariant mass 60 < M(ll) < 120 GeV, at least one b jet at the hadron level
with pT > 25 GeV and abs(eta) < 2.1, and a separation between the leptons and
the jets of Delta R > 0.5 is found to be 5.84 +/- 0.08 (stat.) +/- 0.72 (syst.)
+(0.25)/-(0.55) (theory) pb. The kinematic properties of the events are also
studied and found to be in agreement with the predictions made by the MadGraph
event generator with the parton shower and the hadronisation performed by
PYTHIA.Comment: Submitted to the Journal of High Energy Physic
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