Elaboração do Mapa de Risco em uma indústria de Biossegurança

Os Mapas de Riscos são uma representação gráfica de um conjunto de fatores presentes nos locais de trabalho, capazes de acarretar prejuízos à saúde dos trabalhadores, tais como acidentes e doenças de trabalho. Tem como função à conscientização e informação dos trabalhadores por meio da fácil visualização dos riscos existentes no seu local de trabalho. Este estudo teve como objetivo a elaboração do Mapa de Riscos em uma empresa de Biossegurança, a qual possui muitas áreas de insalubridade na realização de suas atividades. O método de abordagem adotado foi o qualitativo. A pesquisa classifica-se quanto aos fins, como descritiva e explicativa e quanto aos meios como bibliográfica e virtual. Foi possível identificar a importância da existência de Mapas de Riscos na mininmização dos riscos de acidentes que os indivíduos de uma organização ficam expostos diarimente e mapear as áreas de riscos e propor melhorias

Campos de Calibre e o Modelo Padrão de Partículas Elementares: uma revisão pedagógica

O campo de calibre $SU(3)$ do Modelo Padrão (MP) tem sido motivação para uma variedade de estudos. O presente artigo abordará alguns aspectos teóricos da simetria $SU(3)$ no cenário do MP. Serão apresentados o campo de calibre $U(1)$, assim como o campo interação forte. A exibição destes campos serão realizados com o máximo de detalhes possíveis, tratando das respectivas lagrangianas referente a cada um destes

Physical and microbiological quality and oxidative stability in different storage periods of Angus-Nellore heifer meat in an integrated livestock-forest system

This study aimed to evaluate the physical and microbiological quality as well as the oxidative stability of meat stored frozen (30, 60, 90, 180, and 360 days) and obtained from Angus-Nelore heifers kept in a conventional system (CS; no shade available) and Integrated Livestock-Forest (ILF-1L and ILF-3L). Forty-eight ½ Nellore ½ Angus heifers with an average initial weight of approximately 276.70 ± 20.1 kg and an average age of nine months were distributed across a randomized block design with three treatments and four replicates. After slaughter, the Longissimus thoracis muscle was collected from each carcass for pH, lipid oxidation, meat color, and microbiological analyses. The physical and microbiological quality and oxidative stability of the meat were not affected by the tree component present in the pasture. Regarding the duration of frozen storage, it was found that the pH, meat color (a*, b*, C*, H*, O/M), and lipid oxidation increased as the period of storage increased (P<0.05). The physical and microbiological quality, as well as the oxidative stability of the meat, was not affected by the tree component present in the pasture. However, the meat changed as the frozen storage time increased

Impacto clínico, terapêutico e social do canabidiol na epilepsia recorrente / Clinical, therapeutic and social impact of cannabidiol on recurrent epilepsy

Introdução: Estima-se que mais de 50 milhões de pessoas no mundo tenham diagnóstico de epilepsia, no entanto, um terço dessas pessoas não possuem a patologia controlada, apresentando quadros de convulsão e epilepsia recorrente. Desta forma, buscar novas terapêuticas antiepilépticas são necessárias, a atividade antiepiléptica dos canabinóides têm-se mostrado com grande poder terapêutico. Objetivo: Responder quais os impactos clínicos, terapêuticos e sociais do uso do canabidiol (CBD) em pacientes com epilepsia recorrente. Metodologia: Trata-se de uma revisão bibliográfica no método de revisão de integrativa de literatura, realizado entre os meses de abril e maio de 2021, nas bases de dados da MEDLINE/Pubmed e LILACS, por meio dos descritores e operador booleano “Canabidiol” AND “Epilepsia”. Localizando-se artigos publicados entre os anos de 2016 e maio de 2021. Resultados e discussões: O mecanismo de ação ainda não é bem esclarecido, mas é reconhecido sua atuação sobre as manifestações psiquiátricas e neurológicas nas fendas pré-sinápticas. A terapia associada entre CBD e as terapias convencionais para epilepsia apresentaram melhora significativa nos sintomas epilépticos, havendo relatos de melhora completa dos sintomas em até 87,5% dos pacientes. No entanto, cerca de 10% dos pacientes queixam-se de efeitos indesejáveis e desagradáveis como aumento da ansiedade, angústia, medo, tremor e sudorese excessiva durante o tratamento, dado que seu efeito é dose dependente, necessitando de atenção do prescritor para os efeitos indesejados. O impacto social é relatado pelos pacientes como melhora na qualidade de vida e laboral, dada a diminuição da frequência de eventos convulsivos. Conclusão: A terapêutica associada do CBD com a terapia convencional na epilepsia recorrente mostra-se com grandes impactos clínicos e sociais para os pacientes acometidos. No entanto, requer atenção dos prescritores para manifestações clínicas de efeitos colaterais para readequação terapêutica e seguimento. Diante disto, a importância de novos estudos terapêuticos com o CBD é estabelecida pela necessidade de compreender mecanismos de ação e atuação em demais áreas complexas cerebrais que a epilepsia atua para ajudar no tratamento de diversas manifestações desta patologia neurológica

Maternal outcomes and risk factors for COVID-19 severity among pregnant women.

Pregnant women may be at higher risk of severe complications associated with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which may lead to obstetrical complications. We performed a case control study comparing pregnant women with severe coronavirus disease 19 (cases) to pregnant women with a milder form (controls) enrolled in the COVI-Preg international registry cohort between March 24 and July 26, 2020. Risk factors for severity, obstetrical and immediate neonatal outcomes were assessed. A total of 926 pregnant women with a positive test for SARS-CoV-2 were included, among which 92 (9.9%) presented with severe COVID-19 disease. Risk factors for severe maternal outcomes were pulmonary comorbidities [aOR 4.3, 95% CI 1.9-9.5], hypertensive disorders [aOR 2.7, 95% CI 1.0-7.0] and diabetes [aOR2.2, 95% CI 1.1-4.5]. Pregnant women with severe maternal outcomes were at higher risk of caesarean section [70.7% (n = 53/75)], preterm delivery [62.7% (n = 32/51)] and newborns requiring admission to the neonatal intensive care unit [41.3% (n = 31/75)]. In this study, several risk factors for developing severe complications of SARS-CoV-2 infection among pregnant women were identified including pulmonary comorbidities, hypertensive disorders and diabetes. Obstetrical and neonatal outcomes appear to be influenced by the severity of maternal disease

Photography-based taxonomy is inadequate, unnecessary, and potentially harmful for biological sciences

The question whether taxonomic descriptions naming new animal species without type specimen(s) deposited in collections should be accepted for publication by scientific journals and allowed by the Code has already been discussed in Zootaxa (Dubois & Nemésio 2007; Donegan 2008, 2009; Nemésio 2009a–b; Dubois 2009; Gentile & Snell 2009; Minelli 2009; Cianferoni & Bartolozzi 2016; Amorim et al. 2016). This question was again raised in a letter supported by 35 signatories published in the journal Nature (Pape et al. 2016) on 15 September 2016. On 25 September 2016, the following rebuttal (strictly limited to 300 words as per the editorial rules of Nature) was submitted to Nature, which on 18 October 2016 refused to publish it. As we think this problem is a very important one for zoological taxonomy, this text is published here exactly as submitted to Nature, followed by the list of the 493 taxonomists and collection-based researchers who signed it in the short time span from 20 September to 6 October 2016

Impact of COVID-19 on cardiovascular testing in the United States versus the rest of the world

Objectives: This study sought to quantify and compare the decline in volumes of cardiovascular procedures between the United States and non-US institutions during the early phase of the coronavirus disease-2019 (COVID-19) pandemic. Background: The COVID-19 pandemic has disrupted the care of many non-COVID-19 illnesses. Reductions in diagnostic cardiovascular testing around the world have led to concerns over the implications of reduced testing for cardiovascular disease (CVD) morbidity and mortality. Methods: Data were submitted to the INCAPS-COVID (International Atomic Energy Agency Non-Invasive Cardiology Protocols Study of COVID-19), a multinational registry comprising 909 institutions in 108 countries (including 155 facilities in 40 U.S. states), assessing the impact of the COVID-19 pandemic on volumes of diagnostic cardiovascular procedures. Data were obtained for April 2020 and compared with volumes of baseline procedures from March 2019. We compared laboratory characteristics, practices, and procedure volumes between U.S. and non-U.S. facilities and between U.S. geographic regions and identified factors associated with volume reduction in the United States. Results: Reductions in the volumes of procedures in the United States were similar to those in non-U.S. facilities (68% vs. 63%, respectively; p = 0.237), although U.S. facilities reported greater reductions in invasive coronary angiography (69% vs. 53%, respectively; p < 0.001). Significantly more U.S. facilities reported increased use of telehealth and patient screening measures than non-U.S. facilities, such as temperature checks, symptom screenings, and COVID-19 testing. Reductions in volumes of procedures differed between U.S. regions, with larger declines observed in the Northeast (76%) and Midwest (74%) than in the South (62%) and West (44%). Prevalence of COVID-19, staff redeployments, outpatient centers, and urban centers were associated with greater reductions in volume in U.S. facilities in a multivariable analysis. Conclusions: We observed marked reductions in U.S. cardiovascular testing in the early phase of the pandemic and significant variability between U.S. regions. The association between reductions of volumes and COVID-19 prevalence in the United States highlighted the need for proactive efforts to maintain access to cardiovascular testing in areas most affected by outbreaks of COVID-19 infection

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

Compara??o da protra??o maxilar em pacientes portadores de fissura l?bio-palatal por meio de dois protocolos de expans?o r?pida maxilar

Made available in DSpace on 2015-04-14T13:29:57Z (GMT). No. of bitstreams: 1 386492.pdf: 3325358 bytes, checksum: f3483c7295a2158feda0ddb07b9f55a3 (MD5) Previous issue date: 2006-12-14O objetivo deste estudo foi avaliar e comparar os efeitos da protra??o maxilar com m?scara facial em pacientes portadores de fissura l?bio-palatal submetidos a dois protocolos distintos de expans?o r?pida da maxila (ERM). A amostra foi constitu?da de 20 indiv?duos portadores de fissura transforame incisivo unilateral com atresia maxilar (transversal e ?ntero-posterior), com m?dia de idade de 10,4 anos ?2,62, sendo 9 do g?nero masculino e 11 do g?nero feminino. Destes, 10 foram submetidos a uma semana de ERM com ativa??o de 1 volta completa do parafuso expansor por dia, seguido de 23 semanas de protra??o maxilar (Grupo 1). Os outros 10 individuos foram submetidos a sete semanas alternadas de expans?es e constri??es r?pidas da maxila, com ativa??es de 1 volta completa por dia, seguido de 17 semanas de protra??o maxilar (Grupo 2), perfazendo assim um total de 6 meses de tratamento em ambos os grupos. A avalia??o foi realizada por meio de telerradiografias laterais de face, em diferentes tempos: ao in?cio do tratamento (T1), ap?s uma semana de ERM para o Grupo 1 e ap?s as sete semanas alternadas de expans?es e constri??es r?pidas da maxila para o Grupo 2 (T2) e ap?s 24 semanas de tratamento (T3). Os resultados demonstraram um deslocamento da maxila para frente e para baixo, com rota??o anti-hor?ria do plano palatal, rota??o hor?ria da mand?bula, aumento da altura facial ?ntero-inferior e melhora da rela??o maxilo-mandibular. Observou-se tamb?m extrus?o e deslocamento anterior dos molares e incisivos superiores, retroinclina??o dos incisivos inferiores, melhora do perfil mole e da rela??o sagital dos l?bios, com aumento da convexidade facial em ambos os grupos. A ?nica diferen?a estatisticamente significativa identificada entre os grupos ap?s o per?odo de avalia??o foi o maior avan?o do ponto subnasal no Grupo 1 (p=0,05)