Microdosing Mindfulness: Understanding the Effects of Brief Mindfulness Meditation in Children with ADHD

Mindfulness Meditation (MM) is receiving increased empirical support as a method for addressing ADHD symptomology. Research shows that MM interventions lasting weeks or months promote key aspects of cognitive and psycho-emotional functioning in youth with ADHD. Using a pre-post within-subjects design, we sought to determine whether a single MM session supports neurocognitive and/or psycho-emotional functioning in youth with ADHD. Sixteen participants aged 10-14 completed measures of executive and psycho-emotional functioning before/after a 10-minute MM session and silent reading control. Functional neuroimaging assessed whether MM supported changes in prefrontal cortex (PFC) activation during cognitive tasks. We found that a single MM session supported inhibitory control and working memory. Improved inhibitory control also corresponded with a significant increase in PFC activity following MM. This study is the first to demonstrate improvements in key executive functions in youth with ADHD after a single MM session. Limitations, implications and future directions are discussed

Introduction: Empowering Graduate Students in Publication Spaces

In this introduction to the first volume of the sixth issue of Emerging Perspectives: Interdisciplinary Graduate Research in Education and Psychology, we reflect on our experiences as members of the Editorial Team, advocate for the relevancy of graduate student journals, and introduce the three articles featured in this issue

Obstructive sleep apnea syndrome in children: Epidemiology, pathophysiology, diagnosis and sequelae

The prevalence of pediatric obstructive sleep apnea syndrome (OSAS) is approximately 3% in children. Adenotonsillar hypertrophy is the most common cause of OSAS in children, and obesity, hypotonic neuromuscular diseases, and craniofacial anomalies are other major risk factors. Snoring is the most common presenting complaint in children with OSAS, but the clinical presentation varies according to age. Agitated sleep with frequent postural changes, excessive sweating, or abnormal sleep positions such as hyperextension of neck or abnormal prone position may suggest a sleep-disordered breathing. Night terror, sleepwalking, and enuresis are frequently associated, during slow-wave sleep, with sleep-disordered breathing. Excessive daytime sleepiness becomes apparent in older children, whereas hyperactivity or inattention is usually predominant in younger children. Morning headache and poor appetite may also be present. As the cortical arousal threshold is higher in children, arousals are not easily developed and their sleep architectures are usually more conserved than those of adults. Untreated OSAS in children may result in various problems such as cognitive deficits, attention deficit/hyperactivity disorder, poor academic achievement, and emotional instability. Mild pulmonary hypertension is not uncommon. Rarely, cardiovascular complications such as cor pulmonale, heart failure, and systemic hypertension may develop in untreated cases. Failure to thrive and delayed development are serious problems in younger children with OSAS. Diagnosis of pediatric OSAS should be based on snoring, relevant history of sleep disruption, findings of any narrow or collapsible portions of upper airway, and confirmed by polysomnography. Early diagnosis of pediatric OSAS is critical to prevent complications with appropriate interventions

Three-Dimensional Simulations of Kelvin-Helmholtz Instability in Settled Dust Layers in Protoplanetary Disks

As dust settles in a protoplanetary disk, a vertical shear develops because the dust-rich gas in the midplane orbits at a rate closer to true Keplerian than the slower-moving dust-depleted gas above and below. A classical analysis (neglecting the Coriolis force and differential rotation) predicts that Kelvin-Helmholtz instability occurs when the Richardson number of the stratified shear flow is below roughly one-quarter. However, earlier numerical studies showed that the Coriolis force makes layers more unstable, whereas horizontal shear may stabilize the layers. Simulations with a 3D spectral code were used to investigate these opposing influences on the instability in order to resolve whether such layers can ever reach the dense enough conditions for the onset of gravitational instability. I confirm that the Coriolis force, in the absence of radial shear, does indeed make dust layers more unstable, however the instability sets in at high spatial wavenumber for thicker layers. When radial shear is introduced, the onset of instability depends on the amplitude of perturbations: small amplitude perturbations are sheared to high wavenumber where further growth is damped; whereas larger amplitude perturbations grow to magnitudes that disrupt the dust layer. However, this critical amplitude decreases sharply for thinner, more unstable layers. In 3D simulations of unstable layers, turbulence mixes the dust and gas, creating thicker, more stable layers. I find that layers with minimum Richardson numbers in the approximate range 0.2 -- 0.4 are stable in simulations with horizontal shear.Comment: 33 pages, 11 figures (5 color, low-resolution versions), Submitted to The Astrophysical Journal, see http://www.physics.sfsu.edu/~barranco for higher resolution color figures and associated avi animation file

Childhood Obstructive Sleep Apnea Associates with Neuropsychological Deficits and Neuronal Brain Injury

BACKGROUND: Childhood obstructive sleep apnea (OSA) is associated with neuropsychological deficits of memory, learning, and executive function. There is no evidence of neuronal brain injury in children with OSA. We hypothesized that childhood OSA is associated with neuropsychological performance dysfunction, and with neuronal metabolite alterations in the brain, indicative of neuronal injury in areas corresponding to neuropsychological function. METHODS AND FINDINGS: We conducted a cross-sectional study of 31 children (19 with OSA and 12 healthy controls, aged 6–16 y) group-matched by age, ethnicity, gender, and socioeconomic status. Participants underwent polysomnography and neuropsychological assessments. Proton magnetic resonance spectroscopic imaging was performed on a subset of children with OSA and on matched controls. Neuropsychological test scores and mean neuronal metabolite ratios of target brain areas were compared. Relative to controls, children with severe OSA had significant deficits in IQ and executive functions (verbal working memory and verbal fluency). Children with OSA demonstrated decreases of the mean neuronal metabolite ratio N-acetyl aspartate/choline in the left hippocampus (controls: 1.29, standard deviation [SD] 0.21; OSA: 0.91, SD 0.05; p = 0.001) and right frontal cortex (controls: 2.2, SD 0.4; OSA: 1.6, SD 0.4; p = 0.03). CONCLUSIONS: Childhood OSA is associated with deficits of IQ and executive function and also with possible neuronal injury in the hippocampus and frontal cortex. We speculate that untreated childhood OSA could permanently alter a developing child's cognitive potential

Risk Assessment for Patients with Chronic Respiratory Conditions in the Context of the SARS-CoV-2 Pandemic Statement of the German Respiratory Society with the Support of the German Association of Chest Physicians

Assessing the risk for specific patient groups to suffer from severe courses of COVID-19 is of major importance in the current SARS-CoV-2 pandemic. This review focusses on the risk for specific patient groups with chronic respiratory conditions, such as patients with asthma, chronic obstructive pulmonary disease, cystic fibrosis (CF), sarcoidosis, interstitial lung diseases, lung cancer, sleep apnea, tuberculosis, neuromuscular diseases, a history of pulmonary embolism, and patients with lung transplants. Evidence and recommendations are detailed in exemplary cases. While some patient groups with chronic respiratory conditions have an increased risk for severe courses of COVID-19, an increasing number of studies confirm that asthma is not a risk factor for severe COVID-19. However, other risk factors such as higher age, obesity, male gender, diabetes, cardiovascular diseases, chronic kidney or liver disease, cerebrovascular and neurological disease, and various immunodeficiencies or treatments with immunosuppressants need to be taken into account when assessing the risk for severe COVID-19 in patients with chronic respiratory diseases

Recommendations for the implementation of distress screening programs in cancer centers: Report from the American Psychosocial Oncology Society (APOS), Association of Oncology Social Work (AOSW), and Oncology Nursing Society (ONS) joint task force

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/108593/1/cncr28750.pd

Identification of potential surrogate end points in randomized clinical trials of aggressive and indolent non-Hodgkin's lymphoma: correlation of complete response, time-to-event and overall survival end points

Background: The correlation between efficacy end points in randomized controlled trials (RCTs) of systemic therapy for non-Hodgkin's lymphoma (NHL) was investigated to identify an appropriate surrogate end point for overall survival (OS)