Intake, Digestibility, Body Weight and Carcass Characteristics of Tigray Sheep Fed Tef Straw Supplemented with Sesame Seed Meal or Wheat Bran and their Mixtures

The study was conducted over 90 days feeding and 7 days digestibility trials at Enda Selassie ATVET College to assess the effect of supplementation on feed utilization and carcass characteristics in tef (Eragrostis tef) straw based feeding of Tigray rams. The rams were arranged in a randomized complete block design divided into five blocks based on initial BW. The treatments comprised of ad libitum tef straw (control, T1) and daily supplementation with 300 g dry matter (DM) sole sesame (Sesame indicum) seed meal (SSM, T2), 0.65SSM:0.35 wheat bran (WB, T3), 0.35SSM:0.65WB (T4) and sole WB (T5). Tef straw used in the study contained low (30.6 g kg -1 DM) crude protein (CP) andhigh (825.8 g kg -1 DM) neutral detergent fiber (NDF) contrary to the supplement feeds. Total daily DM intake and DM intake as a percentage of BW were higher (P T3 > T4 > T5 > T1. Daily BW gain was negative and lower (P < 0.001) in rams fed solely on tef straw (-22 g g day-1) compared to the supplementedones (50-71.1 g day-1). Out of all supplemented treatments, T5 was lower (P < 0.001) in apparent digestibility of CP and daily BW gain compared to T2, T3 and T4. Hot carcass weight and empty BW were higher (P < 0.001) for T2, T3, T4 compared to T1. Dressing percent on slaughter weight basewas higher (P< 0.001) for supplemented (39.5-43.4%) compared to the control treatment (32.9%). Out of all supplements, SSM and its mixtures with WB resulted in better performance of the sheep compared to supplementation with sole WB.Keywords: Tigray Sheep; Body Weight; Carcass; Intake; Sesame Seed Meal; Tef Straw; Wheat Bra

Experimental evaluation of the wake characteristics of cross flow turbine arrays

One key factor in the exploitation of tidal energy is the study of interactions of turbines when working in tidal turbine farms. The Momentum Reversal and Lift (MRL) turbine is a novel cross flow turbine. The three blades rotate around a common central horizontal axis which is parallel to their own axis and perpendicular to the flow. The novelty of the MRL turbine is that it relies on the combination of both lift and momentum reversal (drag) for energy extraction. Scaled MRL turbine models of 0.164 m in diameter were used to characterise the flow in three different tidal array settings. Detailed maps of axial velocity profiles and velocity deficits downstream of the turbine are presented, enabling the visualisation of characteristic flow patterns. The results show that the MRL generates lower velocity deficits and turbulence intensities in the near wake than those associated with horizontal axis turbines. The downstream wake was not completely symmetrical which was related to the geometry of the device but also due to the flow developed in the flume. Amongst the three array configurations studied, a fence of turbines with the lowest separation provided the highest power output

Multi-objective Optimization of Sustainable Single-Effect Water/Lithium Bromide Absorption Cycle

A rigorous mathematical approach is developed for optimization of sustainable single-effect water/ Lithium Bromide (LiBr) absorption cooling cycles. The multi-objective formulation accounts for minimization of the chiller area as well as the environmental impact associated with the operation of the absorption cycle. The environmental impact is quantified based on the global warming potential and the Eco-indicator 99, both of which follow principles of life cycle assessment. The design task is formulated as a bi-criterion non-linear programming problem, the solution of which is defined by a set of Pareto points that represent the optimal compromise between the total area of the chiller and global warming potential. These Pareto sets are obtained via the epsilon constraint method. A set of design alternatives are provided for the absorption cycles rather than a single design; the best design can be chosen from this set based on the major constraints and benefits in a given application. The proposed approach is illustrated design of a typical absorption cooling cycle

Development of alternative fuel for cement industries: The case of Messebo cement factory in Ethiopia.

The cement industry is struggling with dwindling fossil fuel resources and environmental issues related to climate change. This sector is known for its high energy consumption and generates significant CO2 emissions, accounting for 19% of global thermal energy consumption and 7% of CO2 emissions. For this reason, Cement industries are seeking to replace traditional energy sources with alternative fuels. This study aims to investigate and optimize alternative fuels, evaluating their chemical and physical properties, energy output, production capacity, effect on clinker quality, and impact on combustion flue gas emissions. The study shows that the alternative fuels meet or exceed the minimum international standard of 14 MJ/kg for net calorific value. Therefore, they could replace up to 40% of South African coal in the clinker pre-calcining process. Using alternative fuels such as P. j wood, P. j leaf, P. j charcoal, used tire, and optimized fuels could potentially reduce CO2 emissions by 2%, 9%, 9%, 21%, and 17% respectively. Therefore, policy makers and companies should strongly consider adopting these recommended alternatives

Problematic khat use as a possible risk factor for harmful use of other psychoactive substances: a mixed method study in Ethiopia

Background: Substance use disorders along with neuropsychiatric disorders contributed about 14% of the global burden of disease. Harmful alcohol use, is a known contributor for many harms (accidents, suicide, violence, and complication of other psychiatric and medical disorders). In the Western countries, alcohol and nicotine are gateway drugs to cannabis use, and cannabis use is a risky behavior for other illicit drugs such as cocaine and heroin. Khat use is another psychoactive substance which is common in East African and Arabian Peninsula. But there is a knowledge gap regarding the position of khat use or problematic khat use in sequential progression of different psychoactive substances. Therefore, we aimed to understand and investigate the relationship of problematic khat use and other psychoactive substances in Ethiopia. Methods: Exploratory mixed methods study was employed. Quantitative cross sectional survey was done among 102 khat users, and 4 focus group discussions and 11 in-depth interviews were conducted to understand the pathways between khat use and other psychoactive substances use in 2014. Non random sampling (purposive and snowballing) was employed for both quantitative and qualitative studies. Khat users from khat cafeterias, shops, and from other open markets of khat in Addis Ababa were invited to participate. Result: Currently significant majorities of khat users (86.3%) used at least one other psychoactive substance after they started khat use. The prevalence of harmful drinking was 53.9% among khat users. Problematic khat use was a significant predictor of harmful drinking (p<0.05). About one from ten respondents engaged to risky sexual behavior pushed by the effect of khat after chewing. Conclusion: The proportion of psychoactive substances use especially harmful drinking among khat users was observed higher compared to other cross sectional surveys conducted among general population. In Ethiopia, intervention and policy on harmful alcohol use could consider problematic khat use as one possible risky factor. A rigorous methodology which could test gateway hypothesis

Microalgae biorefinery alternatives and hazard evaluation

Biodiesel production based on microalgae and using carbon dioxide as feedstock constitutes an attractive biofuel alternative. Technology development and process optimization are necessary to minimize the overall production cost. Moreover, in the framework of process sustainability, social and environmental impacts should include process safety aspects. In this context, the objective of this work is to develop a biodiesel production process based on microalgae and the subsequent estimation of the associated risks, thus contributing to more sustainable and safe processes. The biodiesel biorefinery is optimized, taking into account alternative configurations for algae cultivation and lipid extraction. Algae cultivation options are open ponds and tubular photobioreactors. Regarding lipid extraction, dewatering and subsequent n-hexane extraction, and combined ethanol/n-hexane extraction are the studied alternatives. Numerical results showed that open ponds and n-hexane extraction provide maximum net present value. However, n-hexane consumption dramatically rises, and industrial hazards have not been considered in the optimization process. To overcome this issue, a preliminary hazard analysis is carried out to identify hazardous materials and operations. Event trees are formulated to derive the frequencies of different accident scenarios, further determining the consequences. The major consequences of accidents involve toxic releases of high quantities of n-hexane. By comparing the proposed alternatives, this work aims to highlight the need to consider not only economic but also safety and environmental objectives in the development of a biodiesel production project.The authors are grateful for the financial support provided by CONICET and the Spanish MICINN under projects CTQ2013-48280-C3-1-R and CTM2014-57833-R. J. Pinedo would also like to thank the financial support provided by “Becas Iberoamérica JPI España 2014”

Effects of pretreatments of Napier Grass with deionized water, sulfuric acid and sodium hydroxide on pyrolysis oil characteristics

The depletion of fossil fuel reserves has led to increasing interest in liquid bio-fuel from renewable biomass. Biomass is a complex organic material consisting of different degrees of cellulose, hemicellulose, lignin, extractives and minerals. Some of the mineral elements tend to retard conversions, yield and selectivity during pyrolysis processing. This study is focused on the extraction of mineral retardants from Napier grass using deionized water, dilute sodium hydroxide and sulfuric acid and subsequent pyrolysis in a fixed bed reactor. The raw biomass was characterized before and after each pretreatment following standard procedure. Pyrolysis study was conducted in a fixed bed reactor at 600 o�C, 30 �C/min and 30 mL/min N2 flow. Pyrolysis oil (bio-oil) collected was analyzed using standard analytic techniques. The bio-oil yield and characteristics from each pretreated sample were compared with oil from the non-pretreated sample. Bio-oil yield from the raw sample was 32.06 wt% compared to 38.71, 33.28 and 29.27 wt% oil yield recorded from the sample pretreated with sulfuric acid, deionized water and sodium hydroxide respectively. GC–MS analysis of the oil samples revealed that the oil from all the pretreated biomass had more value added chemicals and less ketones and aldehydes. Pretreatment with neutral solvent generated valuable leachate, showed significant impact on the ash extraction, pyrolysis oil yield, and its composition and therefore can be regarded as more appropriate for thermochemical conversion of Napier grass

Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Additionally, we provide subnational disparity analyses to provide a comprehensive overview of anemia prevalence inequalities within these countries and predict progress toward the World Health Organization’s Global Nutrition Target (WHO GNT) to reduce anemia by half by 2030. Our results demonstrate widespread moderate improvements in overall anemia prevalence but identify only three LMICs with a high probability of achieving the WHO GNT by 2030 at a national scale, and no LMIC is expected to achieve the target in all their subnational administrative units. Our maps show where large within-country disparities occur, as well as areas likely to fall short of the WHO GNT, offering precision public health tools so that adequate resource allocation and subsequent interventions can be targeted to the most vulnerable populations

The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

Despite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseases, while others had one or two dominant sources of unit-level burden, with no consistent pattern geographically across the entire subcontinent. Using a subnational counterfactual analysis, we show that nearly 300 million DALYs could have been averted since 2000 by raising all units to their national average. Our findings are directly relevant for decision-makers in determining which and targeting where the most appropriate interventions are for increasing child survival. © 2022, The Author(s).Funding text 1: This work was primarily supported by grant OPP1132415 from the Bill & Melinda Gates Foundation. ; Funding text 2: This study was funded by the Bill & Melinda Gates Foundation. The corresponding author had full access to all the data in the study and had final responsibility for the decision to submit for publication. The non-consortium authors have no competing interests . Competing interests for consortium authors is as follows: Robert Ancuceanu reports receiving consultancy or speaker feeds from UCB, Sandoz, Abbvie, Zentiva, Teva, Laropharm, CEGEDIM, Angelini, Biessen Pharma, Hofigal, AstraZeneca, and Stada. Jacek Jerzy Jozwiak reports personal fees from Amgen, ALAB Laboratories, Teva, Synexus, Boehringer Ingelheim, and Zentiva, all outside the submitted work. Kewal Krishan reports non-financial support from UGC Centre of Advanced Study, CAS II, Department of Anthropology, Panjab University, Chandigarh, India, outside the submitted work. Walter Mendoza is a Program Analyst in Population and Development at the United Nations Population Fund-UNFPA Country Office in Peru, which does not necessarily endorse or support these findings. Maarten J Postma reports grants and personal fees from MSD, GSK, Pfizer, Boehringer Ingelheim, Novavax, BMS, Seqirus, Astra Zeneca, Sanofi, IQVIA, grants from Bayer, BioMerieux, WHO, EU, FIND, Antilope, DIKTI, LPDP, Budi, personal fees from Novartis, Quintiles, Pharmerit, owning stock options in Health-Ecore and PAG Ltd, and being advisor to Asc Academics, all outside the submitted work. Jasviner A Singh reports personal fees from Crealta/Horizon, Medisys, Fidia, UBM LLC, Trio health, Medscape, WebMD, Clinical Care options, Clearview healthcare partners, Putnam associates, Focus forward, Navigant consulting, Spherix, Practice Point communications, the National Institutes of Health, the American College of Rheumatology, and Simply Speaking, owning stock options in Amarin, Viking, Moderna, Vaxart pharmaceuticals and Charlotte’s Web Holdings, being a member of FDA Arthritis Advisory Committee, the steering committee of OMERACT, an international organization that develops measures for clinical trials and receives arm’s length funding from 12 pharmaceutical companies, and the Veterans Affairs Rheumatology Field Advisory Committee, and acting as Editor and Director of the UAB Cochrane Musculoskeletal Group Satellite Center on Network Meta-analysis, all outside the submitted work. Era Upadhyay has a patent A system and method of reusable filters for anti-pollution mask pending, and a patent A system and method for electricity generation through crop stubble by using microbial fuel cells pending

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019

Summary: Background Documentation of patterns and long-term trends in mortality in young people, which reflect huge changes in demographic and social determinants of adolescent health, enables identification of global investment priorities for this age group. We aimed to analyse data on the number of deaths, years of life lost, and mortality rates by sex and age group in people aged 10–24 years in 204 countries and territories from 1950 to 2019 by use of estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods We report trends in estimated total numbers of deaths and mortality rate per 100 000 population in young people aged 10–24 years by age group (10–14 years, 15–19 years, and 20–24 years) and sex in 204 countries and territories between 1950 and 2019 for all causes, and between 1980 and 2019 by cause of death. We analyse variation in outcomes by region, age group, and sex, and compare annual rate of change in mortality in young people aged 10–24 years with that in children aged 0–9 years from 1990 to 2019. We then analyse the association between mortality in people aged 10–24 years and socioeconomic development using the GBD Socio-demographic Index (SDI), a composite measure based on average national educational attainment in people older than 15 years, total fertility rate in people younger than 25 years, and income per capita. We assess the association between SDI and all-cause mortality in 2019, and analyse the ratio of observed to expected mortality by SDI using the most recent available data release (2017). Findings In 2019 there were 1·49 million deaths (95% uncertainty interval 1·39–1·59) worldwide in people aged 10–24 years, of which 61% occurred in males. 32·7% of all adolescent deaths were due to transport injuries, unintentional injuries, or interpersonal violence and conflict; 32·1% were due to communicable, nutritional, or maternal causes; 27·0% were due to non-communicable diseases; and 8·2% were due to self-harm. Since 1950, deaths in this age group decreased by 30·0% in females and 15·3% in males, and sex-based differences in mortality rate have widened in most regions of the world. Geographical variation has also increased, particularly in people aged 10–14 years. Since 1980, communicable and maternal causes of death have decreased sharply as a proportion of total deaths in most GBD super-regions, but remain some of the most common causes in sub-Saharan Africa and south Asia, where more than half of all adolescent deaths occur. Annual percentage decrease in all-cause mortality rate since 1990 in adolescents aged 15–19 years was 1·3% in males and 1·6% in females, almost half that of males aged 1–4 years (2·4%), and around a third less than in females aged 1–4 years (2·5%). The proportion of global deaths in people aged 0–24 years that occurred in people aged 10–24 years more than doubled between 1950 and 2019, from 9·5% to 21·6%. Interpretation Variation in adolescent mortality between countries and by sex is widening, driven by poor progress in reducing deaths in males and older adolescents. Improving global adolescent mortality will require action to address the specific vulnerabilities of this age group, which are being overlooked. Furthermore, indirect effects of the COVID-19 pandemic are likely to jeopardise efforts to improve health outcomes including mortality in young people aged 10–24 years. There is an urgent need to respond to the changing global burden of adolescent mortality, address inequities where they occur, and improve the availability and quality of primary mortality data in this age group