365 research outputs found

    A framework for deflated and augmented Krylov subspace methods

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    We consider deflation and augmentation techniques for accelerating the convergence of Krylov subspace methods for the solution of nonsingular linear algebraic systems. Despite some formal similarity, the two techniques are conceptually different from preconditioning. Deflation (in the sense the term is used here) "removes" certain parts from the operator making it singular, while augmentation adds a subspace to the Krylov subspace (often the one that is generated by the singular operator); in contrast, preconditioning changes the spectrum of the operator without making it singular. Deflation and augmentation have been used in a variety of methods and settings. Typically, deflation is combined with augmentation to compensate for the singularity of the operator, but both techniques can be applied separately. We introduce a framework of Krylov subspace methods that satisfy a Galerkin condition. It includes the families of orthogonal residual (OR) and minimal residual (MR) methods. We show that in this framework augmentation can be achieved either explicitly or, equivalently, implicitly by projecting the residuals appropriately and correcting the approximate solutions in a final step. We study conditions for a breakdown of the deflated methods, and we show several possibilities to avoid such breakdowns for the deflated MINRES method. Numerical experiments illustrate properties of different variants of deflated MINRES analyzed in this paper.Comment: 24 pages, 3 figure

    Culture et maladie mentale chez les Inuit du Nunavik

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    Bien que l'on retrouve dans la population Inuit du Grand Nord du Québec (Nunavik) les troubles psychiatriques majeurs décrits dans la nosologie psychiatrique actuelle, la culture influence de manière importante la symptomatologie et l'évolution de ces troubles ainsi que les réactions qu'ils suscitent. Une revue de la littérature, les réflexions que nous inspire une expérience de consultation psychiatrique en milieu Inuit et les premières données d'une recherche ethnographique, indiquent que le développement de services mieux adaptés et sensibles à la réalité de la culture Inuit doit reposer sur l'étude de l'ethnopsychologie Inuit et des attitudes actuelles envers les malades mentaux.While the major psychiatric disorders described in current nosology can be found among the Inuit of Northern Québec (Nunavik), there are important cultural influences on the symptomatology, social response and course of these disorders. A literature review, consideration of experiences with psychiatric consultation among the Inuit and the preliminary results of ongoing ethnographic research underscore the importance of the study of Inuit ethnopsychology and current attitudes toward the mentally ill in developing culturally sensitive psychiatric care

    From DSM to DM-ID

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    ABSTRACTRecognizing the diagnostic challenges that clinicians face when attempting to arrive at an accurate psychiatric diagnosis for individuals with intellectual and developmental disabilities (IDD) co-occurring with mental illness (MI), in 2007 the National Association for the Dually Diagnosed (NADD), in association with the American Psychiatric Association (APA), published Diagnostic Manual—Intellectual Disability (DM-ID): A Textbook of Diagnosis of Mental Disorders in Persons with Intellectual Disability (Fletcher, Loschen, Stavrakaki, & First, 2007). The DM-ID was designed as a companion to the DSM-IV-TR and aimed to assist clinicians to arrive at a more accurate DSM-IV-TR diagnosis for individuals with IDD. In 2013, the American Psychiatric Association published the DSM-5, thus necessitating revision of the DM-ID to incorporate the changes from the DSM-IV-TR to the DSM-5. The authors discuss the need for and development of the original DM-ID and changes in the DSM-5. The authors then offer insight ..

    Fractal properties of forest fires in Amazonia as a basis for modelling pan-tropical burnt area

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    Journal ArticleCurrent methods for modelling burnt area in dynamic global vegetation models (DGVMs) involve complex fire spread calculations, which rely on many inputs, including fuel characteristics, wind speed and countless parameters. They are therefore susceptible to large uncertainties through error propagation, but undeniably useful for modelling specific, small-scale burns. Using observed fractal distributions of fire scars in Brazilian Amazonia in 2005, we propose an alternative burnt area model for tropical forests, with fire counts as sole input and few parameters. This model is intended for predicting large-scale burnt area rather than looking at individual fire events. A simple parameterization of a tapered fractal distribution is calibrated at multiple spatial resolutions using a satellite-derived burnt area map. The model is capable of accurately reproducing the total area burnt (16 387 km2) and its spatial distribution. When tested pan-tropically using the MODIS MCD14ML active fire product, the model accurately predicts temporal and spatial fire trends, but the magnitude of the differences between these estimates and the GFED3.1 burnt area products varies per continent. © Author(s) 2014.Natural Environment Research Council (NERC)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)CAPESScience without Borders programme fellowshi

    The nature and evolution of I. extragalactic radio sources, and II. young stellar clusters

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    Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Physics, 1998.Includes bibliographical references (p. 611-627).by André B. Fletcher.Ph.D

    Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity.

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    MYCBP2 is a ubiquitin (Ub) E3 ligase (E3) that is essential for neurodevelopment and regulates axon maintenance. MYCBP2 transfers Ub to nonlysine substrates via a newly discovered RING-Cys-Relay (RCR) mechanism, where Ub is relayed from an upstream cysteine to a downstream substrate esterification site. The molecular bases for E2-E3 Ub transfer and Ub relay are unknown. Whether these activities are linked to the neural phenotypes is also unclear. We describe the crystal structure of a covalently trapped E2~Ub:MYCBP2 transfer intermediate revealing key structural rearrangements upon E2-E3 Ub transfer and Ub relay. Our data suggest that transfer to the dynamic upstream cysteine, whilst mitigating lysine activity, requires a closed-like E2~Ub conjugate with tempered reactivity, and Ub relay is facilitated by a helix-coil transition. Furthermore, neurodevelopmental defects and delayed injury-induced degeneration in RCR-defective knock-in mice suggest its requirement, and that of substrate esterification activity, for normal neural development and programmed axon degeneration

    The young stellar population in the Serpens Cloud Core: An ISOCAM survey

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    We present results from an ISOCAM survey in the two broad band filters LW2 (5-8.5 mu) and LW3 (12-18 mu) of a 0.13 square degree coverage of the Serpens Main Cloud Core. A total of 392 sources were detected in the 6.7 mu band and 139 in the 14.3 mu band to a limiting sensitivity of ~ 2 mJy. Only about 50% of the mid-IR excess sources show excesses in the near-IR J-H/H-K diagram. In the central Cloud Core the Class I/Class II number ratio is 19/18, i.e. about 10 times larger than in other young embedded clusters such as rho Ophiuchi or Chamaeleon. The mid-IR fluxes of the Class I and flat-spectrum sources are found to be on the average larger than those of Class II sources. Stellar luminosities are estimated for the Class II sample, and its luminosity function is compatible with a coeval population of about 2 Myr which follows a three segment power-law IMF. For this age about 20% of the Class IIs are found to be young brown dwarf candidates. The YSOs are in general strongly clustered, the Class I sources more than the Class II sources, and there is an indication of sub-clustering. The sub-clustering of the protostar candidates has a spatial scale of 0.12 pc. These sub-clusters are found along the NW-SE oriented ridge and in very good agreement with the location of dense cores traced by millimeter data. The smallest clustering scale for the Class II sources is about 0.25 pc, similar to what was found for rho Ophiuchi. Our data show evidence that star formation in Serpens has proceeded in several phases, and that a ``microburst'' of star formation has taken place very recently, probably within the last 10^5 yrs.Comment: 25 pages, 14 figures, accepted by A&A March 18th, see also http://www.not.iac.es/~amanda

    A Bright, Slow Cryogenic Molecular Beam Source for Free Radicals

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    We demonstrate and characterize a cryogenic buffer gas-cooled molecular beam source capable of producing bright beams of free radicals and refractory species. Details of the beam properties (brightness, forward velocity distribution, transverse velocity spread, rotational and vibrational temperatures) are measured under varying conditions for the molecular species SrF. Under typical conditions we produce a beam of brightness 1.2 x 10^11 molecules/sr/pulse in the rovibrational ground state, with 140 m/s forward velocity and a rotational temperature of approximately 1 K. This source compares favorably to other methods for producing beams of free radicals and refractory species for many types of experiments. We provide details of construction that may be helpful for others attempting to use this method.Comment: 15 pages, 14 figure

    Modeling the growth of stylolites in sedimentary rocks

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    [1] Stylolites are ubiquitous pressure solution seams found in sedimentary rocks. Their morphology is shown to follow two self-affine regimes. Analyzing the scaling properties of their height over their average direction shows that (1) at small scale, they are self-affine surfaces with a Hurst exponent around 1, and (2) at large scale, they follow another self-affine scaling with Hurst exponent around 0.5. In the present paper, we show theoretically the influence of the main principal stress and the local geometry of the stylolitic interface on the dissolution reaction rate. We compute how it is affected by the deviation between the principal stress axis and the local interface between the rock and the soft material in the stylolite. The free energy entering in the dissolution reaction kinetics is expressed from the surface energy term and via integration from the stress perturbations due to these local misalignments. The resulting model shows the interface evolution at different stress conditions. In the stylolitic case, i.e., when the main principal stress is normal to the interface, two different stabilizing terms dominate at small and large scales which are linked respectively to the surface energy and to the elastic interactions. Integrating the presence of small-scale heterogeneities related to the rock properties of the grains in the model leads to the formulation of a Langevin equation predicting the dynamic evolution of the surface. This equation leads to saturated surfaces obeying the two observed scaling laws. Analytical and numerical analysis of this surface evolution model shows that the crossover length separating both scaling regimes depends directly on the applied far-field stress magnitude. This method gives the basis for the development of a paleostress magnitude marker. We apply the computation of this marker, i.e., the morphological analysis, on a stylolite found in the Dogger limestone layer located in the neighborhood of the ANDRA Underground Research Laboratory at Bure (eastern France). The results are consistent with the two scaling regimes expected, and the practical determination of the major principal paleostress, from the estimation of a crossover length, is illustrated on this example

    MGC2214+3550: A New Binary Quasar

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    We report the discovery of a binary quasar, MGC2214+3550 A,B, whose components have similar optical spectra at a redshift z=0.88. The quasars are separated on the sky by 3.0", and have a magnitude difference of Delta(m_I)=0.5 mag. The VLA radio map at 3.6 cm shows a single 47mJy radio source with a core-jet morphology that is coincident with the brighter optical quasar A. Gravitational lensing is ruled out by the lack of radio emission from quasar B, and the lack of any visible galaxies to act as the lens. We conclude that MGC 2214+3550 A and B are physically associated. With a projected separation of 12.7h^{-1} kpc (Omega_0=1), MGC 2214+3550 A,B is one of the smallest z>0.5 binary quasars.Comment: 13 pages, 3 .ps figs, submitted to ApJ
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