Gestational Diabetes: Maternal, Fetal and Neonatal Outcomes Evaluation

Diabetes Gestacional: Avaliação dos Desfechos Maternos, Fetais e NeonataisIntrodução: Apesar dos progressos na vigilância e tratamento da diabetes gestacional (DG), os resultados obstétricos e neonatais ainda não igualaram os da gravidez sem esta complicação. Este estudo pretendeu caracterizar uma população de grávidas com DG comparando-a com uma população obstétrica com rastreio de DG negativo. Material e Métodos: Realizámos um estudo observacional e retrospetivo, através da consulta de processos clínicos de 201 grávidas com DG e 201 grávidas com rastreio de DG negativo, com seguimento e parto no nosso hospital. Resultados: As grávidas com DG apresentaram idade mais avançada (33 vs 31 anos, p = 0,001) e maior prevalência de hipertensão gestacional (6% vs 2%, p = 0,041). O grupo da DG registou uma taxa de cesariana mais elevada (40,3% vs 24,4%, p = 0,001), sendo a incompatibilidade céfalo-pélvica o principal motivo de cesariana (32,9%). Não se verificaram diferenças entre os grupos relativamente ao peso fetal ao nascimento. Recém-nascidos de mães com DG tiveram mais distócia de ombros (3% vs 0%, p = 0,014) e foram mais frequentemente admitidos da Unidade de Cuidados Intensivos Neonatais (14,9% vs 8,5%, p = 0,044), principalmente por hipoglicemia. Não foram encontrados fatores de risco para este desfecho. Discussão: Grávidas com DG eram mais velhas, apresentaram maior incidência de hipertensão gestacional, parto por cesariana e morbilidade neonatal relativamente ao grupo controlo. Conclusão: No presente estudo, a ocorrência de DG condicionou um aumento da morbilidade obstétrica e, sobretudo, neonatal.Introduction: Recently, improvements have been made in the screening and treatment of gestational diabetes (GD). Nevertheless, outcomes in pregnancies complicated by GD have not yet reached those without this complication. The main purpose of this study was to characterize a population of pregnant women with GD and compare it with a population of pregnant women with negative screening for GD. Material and Methods: We conducted an observational and retrospective study, based on consultation of clinical data from 201 women diagnosed with GD and 201 women with negative screening of GD, who have had follow-up of pregnancy and delivery in our hospitalinfo:eu-repo/semantics/publishedVersio

A pediatric case of Cowden Syndrome with Graves' disease

Cowden syndrome (CS) is a rare dominantly inherited multisystem disorder, characterized by an extraordinary malignant potential. In 80% of cases, the human tumor suppressor gene phosphatase and tensin homolog (PTEN) is mutated. We present a case of a 17-year-old boy with genetically confirmed CS and Graves' disease (GD). At the age of 15, he presented with intention tremor, palpitations, and marked anxiety. On examination, he had macrocephaly, coarse facies, slight prognathism, facial trichilemmomas, abdominal keratoses, leg hemangioma, and a diffusely enlarged thyroid gland. He started antithyroid drug (ATD) therapy with methimazole and, after a 2-year treatment period without achieving a remission status, a total thyroidectomy was performed. Diagnosis and management of CS should be multidisciplinary. Thyroid disease is frequent, but its management has yet to be fully defined. The authors present a case report of a pediatric patient with CS and GD and discuss treatment options.info:eu-repo/semantics/publishedVersio

Universidade e redes de atenção à saúde: uma produção de conhecimento no Sistema Único de Saúde

Prefácio de Flávio Adriano Borges MeloComo promover uma formação em saúde sensível e eticamente compromissada com a implementação e o fortalecimento do Sistema Único de Saúde? Como aproximar a formação profissional da realidade da rede de atenção à saúde local? Quais os desafios encontrados na integração entre ensino e serviços? Quais as potencialidades de aprendizagem no contexto do Sistema Único de Saúde? Neste livro são apresentados relatos produzidos por participantes do PET-Saúde e do Pró-Saúde do CCS/UFRB no município de Santo Antônio de Jesus, ao longo dos quais se busca responder a estas e outras questões relevantes para o debate nacional sobre as políticas de saúde

Characterisation of microbial attack on archaeological bone

As part of an EU funded project to investigate the factors influencing bone preservation in the archaeological record, more than 250 bones from 41 archaeological sites in five countries spanning four climatic regions were studied for diagenetic alteration. Sites were selected to cover a range of environmental conditions and archaeological contexts. Microscopic and physical (mercury intrusion porosimetry) analyses of these bones revealed that the majority (68%) had suffered microbial attack. Furthermore, significant differences were found between animal and human bone in both the state of preservation and the type of microbial attack present. These differences in preservation might result from differences in early taphonomy of the bones. © 2003 Elsevier Science Ltd. All rights reserved

NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the Neotropics

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or involuntarily introduced by humans into the Neotropics. Our data set is composed of 73,738 historical and current georeferenced records on alien mammal species of which around 96% correspond to occurrence data on 77 species belonging to eight orders and 26 families. Data cover 26 continental countries in the Neotropics, ranging from Mexico and its frontier regions (southern Florida and coastal-central Florida in the southeast United States) to Argentina, Paraguay, Chile, and Uruguay, and the 13 countries of Caribbean islands. Our data set also includes neotropical species (e.g., Callithrix sp., Myocastor coypus, Nasua nasua) considered alien in particular areas of Neotropics. The most numerous species in terms of records are from Bos sp. (n = 37,782), Sus scrofa (n = 6,730), and Canis familiaris (n = 10,084); 17 species were represented by only one record (e.g., Syncerus caffer, Cervus timorensis, Cervus unicolor, Canis latrans). Primates have the highest number of species in the data set (n = 20 species), partly because of uncertainties regarding taxonomic identification of the genera Callithrix, which includes the species Callithrix aurita, Callithrix flaviceps, Callithrix geoffroyi, Callithrix jacchus, Callithrix kuhlii, Callithrix penicillata, and their hybrids. This unique data set will be a valuable source of information on invasion risk assessments, biodiversity redistribution and conservation-related research. There are no copyright restrictions. Please cite this data paper when using the data in publications. We also request that researchers and teachers inform us on how they are using the data

Núcleos de Ensino da Unesp: artigos 2007

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora