Central Indiana STEM Talent Expansion Program: Student and Faculty Interventions

Funded by 5-year, $2M grant from the National Science Foundation, the Central Indiana STEM Talent Expansion Program (CI-STEP) at Indiana University-Purdue University Indianapolis (IUPUI) is creating a pipeline of students and a campus culture change to increase the number of undergraduates obtaining Science, Technology, Engineering, and Mathematics (STEM) degrees. CI-STEP addresses initiatives needed for transforming the undergraduate STEM experience by propagating, expanding, and creating new evidence-based educational innovations in undergraduate STEM education at IUPUI

Science of Extreme Light Infrastructure

The infrastructure of Extreme Light Infrastructure (ELI) provides an unprecedented opportunity for a broad range of frontier science. Its highest ever intensity of lasers, as well as high fluence, high power, and/or ultrafast optical characteristics carve out new territories of discovery, ranging from attosecond science to photonuclear science, laser acceleration and associated beams, and high field science (Four Pillars of ELI). Its applications span from medicine, biology, engineering, energy, chemistry, physics, and fundamental understanding of the Universe. The relativistic optics that intense lasers have begun exploring may be extended into a new regime of ultra‐relativistic regime, where even protons fly relativistically in the optical fields. ELI provides the highest intensity to date such that photon fields begin to feel even the texture of vacuum. This is a singular appeal of ELI with its relatively modest infrastructure (compared to the contemporary largest scientific infrastructures), yet provides an exceptional avenue along which the 21st Century science and society need to answer the toughest questions. The intensity frontier simultaneously brings in the energy horizon (TeV and PeV) as well as temporal frontier (attoseconds and zeptoseconds). It also turns over optics of atoms and molecules into that of nuclei with the ability to produce monoenergetic collimated γ‐ray photons. As such, the ELI concept acutely demands an effort to encompass and integrate its Four Pillars

VUV/EUV ionising radiation and atoms and ions: dual laser plasma investigations

The interaction of ionising radiation with atoms and ions is a key fundamental process. This report concentrates on studies of photoexcitation/photoionisation using laser-produced plasmas as continuum sources and synchronised laser plasma plumes to provide the absorbing atom or ion species. Examples from studies of the interaction of ionising radiation with atoms and ions ranging from few-electron atomic and ionic systems to the many-electron high atomic number actinides are reviewed and illustrate the advantages and limitations of the Dual Laser Plasma technique

First Observation of Self-Amplified Spontaneous Emission in a Free-Electron Laser at 109 nm Wavelength

We present the first observation of Self-Amplified Spontaneous Emission (SASE) in a free-electron laser (FEL) in the Vacuum Ultraviolet regime at 109 nm wavelength (11 eV). The observed free-electron laser gain (approx. 3000) and the radiation characteristics, such as dependency on bunch charge, angular distribution, spectral width and intensity fluctuations all corroborate the existing models for SASE FELs.Comment: 6 pages including 6 figures; e-mail: [email protected]

Violence in primary care: Prevalence and follow-up of victims

BACKGROUND: Primary care physicians underestimate the prevalence of domestic violence and community violence. Victims are therefore at risk of further episodes of violence, with psychological and physical consequences. We used an interview to assess the prevalence of domestic and community violence among Swiss natives and foreigners. In a follow-up study, we evaluated the consequences of the interview for the positive patients. METHODS: We evaluated the prevalence of violence by use of a questionnaire in an interview, in an academic general internal medicine clinic in Switzerland. In a follow-up, we evaluated the consequences of the interview for positive patients. The participants were 38 residents and 446 consecutive patients. Questionnaires were presented in the principal language spoken by our patients. They addressed sociodemographics, present and past violence, the security or lack of security felt by victims of violence, and the patients' own violence. Between 3 and 6 months after the first interview, we did a follow-up of all patients who had reported domestic violence in the last year. RESULTS: Of the 366 patients included in the study, 36 (9.8%) reported being victims of physical violence during the last year (physicians identified only 4 patients out of the 36), and 34/366 (9.3%) reported being victims of psychological violence. Domestic violence was responsible for 67.3% of the cases, and community violence for 21.8%. In 10.9% of the cases, both forms of violence were found. Of 29 patients who reported being victims of domestic violence, 22 were found in the follow-up. The frequency of violence had diminished (4/22) or the violence had ceased (17/22). CONCLUSION: The prevalence of violence is high; domestic violence is more frequent than community violence. There was no statistically significant difference between the Swiss and foreign patients' responses related to the rates of violence. Patients in a currently violent relationship stated that participating in the study helped them and that the violence decreased or ceased a few months later

The prevalence of exposure to domestic violence and the factors associated with co-occurrence of psychological and physical violence exposure: a sample from primary care patients

<p>Abstract</p> <p>Background</p> <p>Since many health problems are associated with abuse and neglect at all ages, domestic violence victims may be considered as a group of primary care patients in need of special attention.</p> <p>Methods</p> <p>The aim of this multi-centre study was to assess the prevalence of domestic violence in primary care patients, and to identify those factors which influence the co-occurrence of psychological and physical violence exposure and their consequences (physical, sexual and reproductive and psychological) as obtained from medical records.</p> <p>A study was carried out in 28 family practices in Slovenia in 2009. Twenty-eight family physicians approached every fifth family practice attendee, regardless of gender, to be interviewed about their exposure to domestic violence and asked to specify the perpetrator and the frequency. Out of 840 patients asked, 829 individuals, 61.0% women (n = 506) and 39.0% men (n = 323) were assessed (98.7% response rate). They represented a randomised sample of general practice attendees, aged 18 years and above, who had visited their physician for health problems and who were given a physical examination. Visits for administrative purposes were excluded.</p> <p>Multivariate binary logistic regression analysis was used to determine the factors associated with exposure to both psychological and physical violence.</p> <p>Results</p> <p>Of 829 patients, 15.3% reported some type of domestic violence experienced during the previous five years; 5.9% reported physical and 9.4% psychological violence; of these 19.2% of men and 80.8% of women had been exposed to psychological violence, while 22.4% of men and 77.6% of women had been exposed to physical violence. The domestic violence victims were mostly women (p < 0.001) aged up to 35 years (p = 0.001). Exposure to psychological violence was more prevalent than exposure to physical violence. Of the women, 20.0% were exposed to either type of violence, compared to 8.0% of male participants, who reported they were rarely exposed to physical violence, while women reported often or constant exposure to physical violence. Their partners were mostly the perpetrators of domestic violence towards women, while amongst men the perpetrators were mostly other family members.</p> <p>In univariate analysis female gender was shown to be a risk factor for domestic violence exposure. Regression modelling, explaining 40% of the variance, extracted two factors associated with psychological and physical violence exposure: the abuse of alcohol in the patient (OR 4.7; 95% CI 1.54-14.45) and their unemployment (OR 13.3; 95% CI 1.53-116.45).</p> <p>Conclusions</p> <p>As far as the study design permits, the identified factors associated with both psychological and physical violence exposure could serve as determinants to raise family physicians' awareness when exploring the prevalence of domestic violence. The results of previous research, showing at least 15% prevalence of exposure to domestic violence among primary care patients in Slovenia, and the female gender as a risk factor, were confirmed.</p

PENGARUH PENAMBAHAN CACAHAN LIMBAH PLASTIK JENIS HIGH DENSITY POLYETHYLENE (HDPE) PADA

Waste is a very complex problem in urban area. Plastic waste is increasing every year. Kupang with population of 291,794 people generate waste reaches 926 m3/day. Organic waste to 700 m3 and inorganic waste about 226 m3. Concrete is planned by strength quality 25 MPa. Based on the analysis in this study obtained that concrete flexural strength value increased due to the addition of HDPE plastic shredded into the concrete, with chopped levels are added to the concrete at 0%, 0.50% and 0.90% .0,70%. Flexural strength value of normal concrete without the addition of shredded plastic (0%) is 4.12 MPa, flexural strength of concrete with the addition of shredded plastic 0.50% is 4.30 MPa increased 4.37% from normal concrete flexural strength, flexural strength of concrete with the addition of shredded plastics 0.70% is 4.21 MPa increased 2.19% from the normal concrete flexural strength and flexural strength of concrete with the addition of shredded plastic 0.90% is 3.94 MPa decreased 3.64% of flexural strength normal concrete

Innate Immune Deficiency of Extremely Premature Neonates Can Be Reversed by Interferon-γ

Background: Bacterial sepsis is a major threat in neonates born prematurely, and is associated with elevated morbidity and mortality. Little is known on the innate immune response to bacteria among extremely premature infants. Methodology/Principal Findings: We compared innate immune functions to bacteria commonly causing sepsis in 21 infants of less than 28 wks of gestational age, 24 infants born between 28 and 32 wks of gestational age, 25 term newborns and 20 healthy adults. Levels of surface expression of innate immune receptors (CD14, TLR2, TLR4, and MD-2) for Grampositive and Gram-negative bacteria were measured in cord blood leukocytes at the time of birth. The cytokine response to bacteria of those leukocytes as well as plasma-dependent opsonophagocytosis of bacteria by target leukocytes was also measured in the presence or absence of interferon-c. Leukocytes from extremely premature infants expressed very low levels of receptors important for bacterial recognition. Leukocyte inflammatory responses to bacteria and opsonophagocytic activity of plasma from premature infants were also severely impaired compared to term newborns or adults. These innate immune defects could be corrected when blood from premature infants was incubated ex vivo 12 hrs with interferon-c. Conclusion/Significance: Premature infants display markedly impaired innate immune functions, which likely account for their propensity to develop bacterial sepsis during the neonatal period. The fetal innate immune response progressivel