114 research outputs found

    Forecast Model of Prices for Liquefied Natural Gas in the World Asian Energy Market

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    The relevance of the study lies in the fact that concerning the strategic objectives of Russia to take a share of the growing world market of liquefied natural gas, it is advisable to assess the impact of factors affecting the development of the global liquefied natural gas market. This article provides a comparative analysis of exports and imports in the global LNG market by region, identifies potential trends in the development of global LNG trade over the past 50 years, it makes a price forecast for liquefied natural gas (LNG) for the Asia-Pacific region (APR) based on a correlation and regression analysis of the dependence of LNG prices on changes in factors such as world oil prices, global demand for LNG, exchange rates and growth rates of the Asia-Pacific economies

    The Arctic Countries’ Supply Chain Strategies in The Context of Arctic Territory Delimitation

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    The article discusses the supply chain strategies of the so-termed Arctic Five – the Russian Federation, Canada, the USA, Norway and Denmark, which have borders in the Arctic in the context of the search for their common goals and objectives in order to develop possible ways and means to solve the main common problem – the territory delimitation in the Arctic between these countries. Much has been written about the legal methods of maritime delimitation in the Arctic, but their essence is to compare the principles of “Sectoral division†in the Arctic with the norms of the 1982 “United Nations Convention on the Law of the Seaâ€. Meanwhile, the current international situation and the current state of the Arctic countries in relation to each other in the sphere of military power, economy, science and climate change in the Arctic, force us to consider the issue of territory delimitation in the Arctic in an extensive aspect.Â

    History and prospects of natural gas pricing in Continental Europe in conditions of instability of world oil prices

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    The article substantiates the need to assess changes in world prices for natural gas in conditions of volatility in world oil prices. The study is aimed at making forecasts of changes in world prices for natural gas in Continental Europe based on historical trend analysis.The main method of the study is the method of correlation-regression analysis, with the help of which the strength of the correlation of world prices for natural gas from world oil prices was revealed. Also, methods of historical trend and mathematical analysis were used to determine the main forecast scenarios for natural gas price levels. The study is a new approach to analyzing the pricing of world prices for natural gas based on the revealed dependence on world oil prices.The article examines the natural gas market of Continental Europe in dynamics and analyzes its evolution, as well as a link to the world oil market to make forecasts of the cost of natural gas.peer-reviewe

    Forecast scenarios of world prices for natural gas

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    The study proposes forecast scenarios for the development of world prices for natural gas based on economic and mathematical modeling and the analysis of the historical trend of extraction, consumption, export and import of natural gas.The main research method is correlation-regression analysis which allowed establishing how strong the correlation of world prices for natural gas and world oil prices is. Also, the methods of historical trend and mathematical analysis were used to determine the main forecast scenarios for price levels of natural gas.The study represents a new approach to the analysis of the dynamics of world prices for natural gas based on economic and mathematical modeling.The article examines the dynamics of the global natural gas market and analyzes trends in price changes, as well as establishes the relationship between global prices for natural gas and the world oil market for making forecasts of the cost of natural gas.peer-reviewe

    Conditions for Effective Long-Term Energy Supply to the Arctic Areas of the Republic of Sakha (Yakutia)

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    This paper presents a comparative assessment of the efficiency of electricity production and consumption in the Eastern Economic Zone (EEZ) of the Republic of Sakha (Yakutia). Based on the analysis, the existing electricity supply risks in the EEZ areas are identified and recommendations for efficient electricity consumption and production in the EEZ areas are developed. The study makes it possible to develop sound recommendations for improving the efficiency of electricity production and consumption in the Oymyakonsky District of the EEZ. No relevant studies of the Eastern Economic Zone, including the Oymyakonsky District in the Republic of Sakha (Yakutia), have been conducted over the past five years. In this regard, the relevance of the study stems from the fact that not only natural but also cost indices of electricity production and consumption are calculated for the first time, and recommendations for efficient electricity consumption are given in the context of the Oymyakonsky District settlements of the EEZ. Keywords: Electric Power, Electricity Generation and Consumption, Eastern Economic Zone. JEL Classifications: Q4, R0, R1 DOI: https://doi.org/10.32479/ijeep.703

    ГЛИКОЗИЛИРОВАНИЕ С-РЕАКТИВНОГО БЕЛКА ПРИ СЕПСИСЕ

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    Методом твердофазного лектин-ферментного анализа изучено изменение гликозилирования глико-протеинов цельной сыворотки крови пациентов с сепсисом и здоровых доноров. Показано, что при сеп-сисе происходит уменьшение разветвленности углеводных структур гликоконъюгатов, увеличение доли О-гликозилированных цепей муцинового типа. Почти на 50 % по сравнению с донорскими сыворотками уменьшается связывание с GlcNAc-специфичными лектинами. Это связано, скорее всего, с экранированием хитобиозного кора и уменьшением структур с бисектным GlcNAc. В образце СРБ, выделенного из сыво-роток больных сепсисом, методами ГЖХ и ГЖХ-МС определены моносахаридные остатки Man, Glc, Gal, GlcNAc, GalNAc, входящие в состав его углеводных цепей. Данные результаты могут существенно повы-сить значимость СРБ как потенциального клинического маркера в лабораторной диагностике. G.B. Elyakov Pacifi c Institute of Bioorganic Chemistry FEB RAS, Vladivostok, e-mail: [email protected] The change of glycoproteins glycosylation of whole blood serum of patients with sepsis and healthy donors was examined by the method of enzyme linked lectin assay. A reduction of carbohydrate structures branching and an increase of the content of O-glycosylated mucin type chains of glycoconjugates in sepsis patients are shown. The binding to GlcNAc-specifi c lectins is reduced by about 50 % compared with donor sera. This is due to shielding of chitobiose core and reducing of bisecting GlcNAc structures. Monosaccharides Man, Glc, Gal, GlcNAc, GalNAc were identifi ed by GC and GC-MS as part of carbohydrate chains of CRP from sera of sepsis patients. These results may increase the importance of CRP as a potential marker in the clinical laboratory diagnosis

    Localization of Secondary Metabolites in Marine Invertebrates: Contribution of MALDI MSI for the Study of Saponins in Cuvierian Tubules of H. forskali

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    BACKGROUND: Several species of sea cucumbers of the family Holothuriidae possess a particular mechanical defense system called the Cuvierian tubules (Ct). It is also a chemical defense system as triterpene glycosides (saponins) appear to be particularly concentrated in Ct. In the present study, the precise localization of saponins in the Ct of Holothuria forskali is investigated. Classical histochemical labeling using lectin was firstly performed but did not generate any conclusive results. Thus, MALDI mass spectrometry Imaging (MALDI-MSI) was directly applied and completed by statistical multivariate tests. A comparison between the tubules of relaxed and stressed animals was realized. RESULTS: These analyses allowed the detection of three groups of ions, corresponding to the isomeric saponins of the tubules. Saponins detected at m/z 1287 and 1303 were the most abundant and were apparently localized in the connective tissue of the tubules of both relaxed and stressed individuals. Saponins at m/z 1125 and 1141 were detected in lower amount and were present in tissues of relaxed animals. Finally, saponin ions at 1433, 1449, 1463 and 1479 were observed in some Ct of stressed holothuroids in the outer part of the connective tissue. The saponin group m/z 14xx seems therefore to be stress-specific and could originate from modifications of the saponins with m/z of 11xx. CONCLUSIONS: All the results taken together indicate a complex chemical defense mechanism with, for a single organ, different sets of saponins originating from different cell populations and presenting different responses to stress. The present study also reflects that MALDI-MSI is a valuable tool for chemical ecology studies in which specific chemical signalling molecules like allelochemicals or pheromones have to be tracked. This report represents one of the very first studies using these tools to provide a functional and ecological understanding of the role of natural products from marine invertebrates

    Significance and potential of marine microbial natural bioactive compounds against biofilms/biofouling: necessity for green chemistry

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    Natural products from the unique environments of sea water and oceans represent a largely unfamiliar source for isolation of new microbes, which are potent producers of secondary bioactive metabolites. These unique life-forms from the marine ecosphere have served as an important source of drugs since ancient times and still offer a valuable resource for novel findings by providing remedial treatments. Therefore, it can be expected that many naturally bioactive marine microbial compounds with novel structures and bioactivities against those from terrestrial environments may be found among marine metabolites. Biofilms in aquatic environment possess serious problems to naval forces and oceanic industries around the globe. Current anti-biofilm or anti-biofouling technology is based on the use of toxic substances that can be harmful to their surrounding natural locales. Comprehensive research has been done to examine the bioactive potential of marine microbes. Results are remarkably varied and dynamic, but there is an urgent need for bioactive compounds with environmentally friendly or “green” chemical activities. Marine microbes have the potential as upcoming and promising source of non-toxic compounds with sustainable anti-biofouling/anti-biofilm properties as they can produce substances that can inhibit not only the chemical components required for biofilm production but also the attachment, microorganism growth, and/or cell–cell communication

    Production of bioactive secondary metabolites by marine Vibrionaceae

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    Abstract: Bacteria belonging to the Vibrionaceae family are widespread in the marine environment. Today, 128 species of vibrios are known. Several of them are infamous for their pathogenicity or symbiotic relationships. Despite their ability to interact with eukaryotes, the vibrios are greatly underexplored for their ability to produce bioactive secondary metabolites and studies have been limited to only a few species. Most of the compounds isolated from vibrios so far are non-ribosomal peptides or hybrids thereof, with examples of N-containing compounds produced independent of nonribosomal peptide synthetases (NRPS). Though covering a limited chemical space, vibrios produce compounds with attractive biological activities, including antibacterial, anticancer, and antivirulence activities. This review highlights some of the most interesting structures from this group of bacteria. Many compounds found in vibrios have also been isolated from other distantly related bacteria. This cosmopolitan occurrence of metabolites indicates a high incidence of horizontal gene transfer, which raises interesting questions concerning the ecological function of some of these molecules. This account underlines the pending potential for exploring new bacterial sources of bioactive compounds and the challenges related to their investigation
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