11 research outputs found

    DEFINING INDICATORS OF COOPERATION NETWORKING ANDLEARNING DEVELOPMENT IN PORT-ZONES’ NEIGHBORHOODS:APPLICABILITY IN ALEXANDRIA AND PORT SUDAN

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    Lately, Cooperation Learning & Networking Development programs (CNL) has approved success in achieving rapid growth in urban areas. Its potentiality to afford remarkable improvement supports the joint learning and cooperative innovation processes in different cities in different territories. Also, networking for cooperative learning is benefiting the technological development in communication means and social media to provide wider involvement in urban growth to achieve better life cities. This paper is aiming to understand the constituents of CNL in urban development. Also, it targets neighborhoods in port areas which need prompt, effective and collective improvement in the urban life of cities in developing countries. This research is held by studying the possibility and applicability of a suggested project for 9 neighborhoods at port zones in Alexandria (Egypt) and Port Sudan (Sudan). The research identifies the potentiality of CNL development by considering assessing indicator. These indicators are studied throughout SWOT analysis and opportunities’ exploring for the prospective growth towards a sustainable development. It also suggests a future extension for the project to include more port zones in similar cities in the region to achieve common goals

    Towards Understanding The Hepatoprotective effect of Grape Seeds Extract on Cholesterol-Fed Rats

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    Abstract: In our previous studies, a phenolic-rich extract of grape seed was prepared under optimal conditions. The antioxidant activity of grape seed extract (GSE) was determined in addition to 50 determination of acute oral LD toxicity. The current work studies the protective effect of GSE on hypercholesterolemia, where, W istar rats fed a standard laboratory diet (control group-CG) or a cholesterol-rich diet (hypercholesterolemic group-HCD) and to see the effect of GSE, another group fed on cholesterol-rich diet enriched with 0.3% GSEW /W-PG) for 8 weeks. Serum lipid levels, serum antioxidant status, Liver and kidney function were analysed in addition to histopathological examination of the liver. The hypocholesterolemic effects of GSE is confirmed by lowering the serum total cholesterol (TC) by 31%, low-density lipoprotein cholesterol LDL-C by 41% and elevated the high-density lipoprotein cholesterol HDL-C by 25% compared to TC, LDL-C and HDL-C of HCD group . Furthermore, the liver function expressed as glutamic pyruvate transaminase (GPT) and Albumin serum levels, decreased significantly and reached to normal level in case of oral administration of GSE. The kidney function showed no adverse effect in all groups. In addition, the antioxidant status serum level was increased as compared to those of rats fed only on cholesterol-rich diet. Histological examination of liver sections confirmed the serum analysis where GSE had a protective effect on animals fed on HCD, the liver of these animals showed mild affection in the form of microvesicular vacuolation of hepatocytes in the peripheral zone of the hepatic lobule (<50%) in comparison to the fatty change observed as microvesicular and macrovesicular vacuolation in >50% and <70% of the liver sections in HCD group. T hese results suggested that the GSE has a hypocholesterolemic effect which might be due to its ability to lower serum TC and LDL-C levels as well as slowing the lipid peroxidation process by enhancing antioxidant enzyme activity

    Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

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    This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic

    Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study

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    Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p\textless0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p\textless0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p\textless0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research

    Writing Christian History in Islamic Egypt :the History of the Patriarchs of Alexandria

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    During the Fatimid period (11th c.), a major enterprise of translation of earlier historical Coptic sources into Arabic took place in Egypt, on the initiative of the Coptic Church. It resulted in the composition of the famous text of the “History of the Patriarchs of Alexandria,” which is considered a major source for the history of Egypt and the Middle East in general. Indeed, in a biographical framework, it offers rich and rare narratives of historical events (from the 1st c. CE onwards), presented from a Coptic point of view. In her lecture, ISAW Visiting Research Scholar Perrine Pilette will present the results of her ongoing research on this corpus, highlighting its multi-linguistic issues as well as its key-position between Christian and Islamic literary heritages
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