Leadership for change

This edited volume reveals how the journey of transformation at the University of the Free State (UFS) became interwoven with student leadership development and global learning. The UFS initiated two intersecting co-curricular programmes, namely, the First-Year Leadership for Change (F1L4C) programme in 2010; and the triennial Global Leadership Summit (GLS) in 2012. Although these programmes changed over time, their core focus remained to be the development of transformational student leaders through the creation of global learning spaces. From its inception in 2010 to the last GLS in 2018, the UFS global learning project involved 780 students and 259 staff members from 109 institutions, across four continents. The goal of this edited volume is to create a deeper understanding of how the UFS F1L4C and GLS programmes enhanced student leadership development through global learning, especially in the context of higher education transformation

Leadership for change

This edited volume reveals how the journey of transformation at the University of the Free State (UFS) became interwoven with student leadership development and global learning. The UFS initiated two intersecting co-curricular programmes, namely, the First-Year Leadership for Change (F1L4C) programme in 2010; and the triennial Global Leadership Summit (GLS) in 2012. Although these programmes changed over time, their core focus remained to be the development of transformational student leaders through the creation of global learning spaces. From its inception in 2010 to the last GLS in 2018, the UFS global learning project involved 780 students and 259 staff members from 109 institutions, across four continents. The goal of this edited volume is to create a deeper understanding of how the UFS F1L4C and GLS programmes enhanced student leadership development through global learning, especially in the context of higher education transformation

Aplicación a una organización pública de salud

El presente trabajo de investigación tuvo como principal objetivo efectuar un diagnóstico de los factores culturales de la organización elegida – Hospital de Emergencias Dr. Clemente Alvarez- para poder apreciar y comprender sus rasgos culturales básicos. El actual Hospital de Emergencias Dr. C. Alvarez es el más importante hospital de adultos de la red municipal, con alto grado de desarrollo en el área de las emergencias, siendo centro de referencia para trauma, accidentología y quemados. Funciona como referente regional atendiendo pacientes de las distintas localidades de la provincia de Santa Fe y provincias vecinas. Es reconocido como centro quirúrgico de alta complejidad en cirugía general ginecológica, urológica, vídeo – endoscópica, máxilo – facial, neuroquirúrgica, oftalmológica, traumatológica y quemados. Se constituye, además, como una unidad docente de pre y posgrado de la Universidad Nacional de Rosario. En la actualidad cuenta con un total de 145 camas de internación, incluidas la Unidad de Terapia Intensiva con 10 camas, Unidad Coronaria con 6 camas y Unidad de Quemados con 7 camas. Existen 4 quirófanos centrales y 2 quirófanos de endoscopia. Su dotación es de aproximadamente 850 personas comprendiendo enfermeros, médicos, técnicos, mucamas, personal de mantenimiento, de vigilancia y administrativos. El estudio se centró, en esta primera etapa, en el Área de Emergencia Primaria _ A.E.P-. conocida comúnmente como Guardia , por ser considerada ésta como una unidad fuerte-mente representativa del perfil del hospital. La investigación será así explicativa y descriptiva (campo de la sociología) más que trans-formacional para moldear la cultura organizacional con intenciones de adaptarla a los pro-pósitos estratégicos (campo de la administración). Las conclusiones podrán ser utilizadas para una reorientación cultural, efectuar cambios socioculturales adaptativos, revitalización de aspectos funcionales y efectuar otras transfor-maciones tenues o profundas. Las propuestas de cambio exceden el alcance de este trabajoFil: Serlin, José . Facultad de Ciencias Económicas y Estadística - Universidad Nacional de Rosario - Argentin

Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors

Generation of stable transgenic embryonic stem (ES) cell lines by classic transfection is still a difficult task, requiring time-consuming clonal selection, and hampered by clonal artifacts and gene silencing. Here we describe a novel system that allows construction of lentivectors and generation of stable ES cell lines with > 99% transgene expression within a very short time frame. Rapid insertion of promoters and genes of interest is obtained through a modular recombinational cloning system. Vectors contain central polypurine tract from HIV-1 element and woodchuck hepatitis virus post-transcriptional regulatory element as well as antibiotic resistance to achieve optimal and homogenous transgene expression. We show that the system 1) is functional in mouse and human ES cells, 2) allows the generation of ES cells expressing genes of interest under the control of ubiquitous or tissue-specific promoters, and 3) allows ES cells expressing two constructs through selection with different antibiotics to be obtained. The technology described herein should become a useful tool in stem cell research

Toxic effects multi-walled carbon nanotubes on bivalves: comparison between of functionalized and non-functionalized nanoparticles

Despite of the large array of available carbon nanotube (CNT) configurations that allow different industrial and scientific applications of these nanoparticles, their impacts on aquatic organisms, especially on invertebrate species, are still limited. To our knowledge, no information is available on how surface chemistry alteration (functionalization) of CNTs may impact the toxicity of these NPs to bivalve species after a chronic exposure. For this reason, the impacts induced by chronic exposure (28 days) to unfunctionalized MWCNTs (Nf-MWCNTs) in comparison with functionalized MWCNTs (f-MWCNTs), were evaluated in R. philippinarum, by measuring alterations induced in clams' oxidative status, neurotoxicity and metabolic capacity. The results obtained revealed that exposure to both MWCNT materials altered energy-related responses, with higher metabolic capacity and lower glycogen, protein and lipid concentrations in clams exposed to these CNTs. Moreover, R. philippinarum exposed to Nf-MWCNTs and f-MWCNTs showed oxidative stress expressed in higher lipid peroxidation and lower ratio between reduced and oxidized glutathione, despite the activation of defense mechanisms (superoxide-dismutase, glutathione peroxidase and glutathione S-transferases) in exposed clams. Additionally, neurotoxicity was observed by inhibition of Cholinesterases activity in organisms exposed to both MWCNTs.publishe

Simpósio de Geoarqueologia: temas abordados e resultados

Resumo: o Simpósio de Geoarqueologia da VI TAAS, coordenado por Rosiclér Theodoro da Silva e Michelle Mayumi Tizuka contou com a apresentação de nove trabalhos de pesquisadores do Brasil, Argentina e Colômbia. Este artigo trata de uma síntese dos temas abordados incluídos em: arqueologia e eventos climáticos, arqueologia e regiões costeiras, arqueologia da paisagem, arqueoestratigrafia, geoarqueologia de sistemas fluviais, arqueologia e vulcanismo. Seu objetivo principal é divulgar os resultados do simpósio e fortalecer a abordagem geoarqueológica nas pesquisas arqueológicas tanto em território nacional como no exterior. Palavras-chave: Geoarqueologia. Teoria Arqueológica. América do Sul

Identidad y cultura organizacional. Aplicación a una organización pública de salud

n.d.Fil: José Serlin. Facultad de Ciencias Económicas y Estadística - Universidad Nacional de Rosario - Argentin

Rapid generation of stable transgenic embryonic stem cell lines using modular lentivectors

Generation of stable transgenic embryonic stem (ES) cell lines by classic transfection is still a difficult task, requiring time-consuming clonal selection, and hampered by clonal artifacts and gene silencing. Here we describe a novel system that allows construction of lentivectors and generation of stable ES cell lines with > 99% transgene expression within a very short time frame. Rapid insertion of promoters and genes of interest is obtained through a modular recombinational cloning system. Vectors contain central polypurine tract from HIV-1 element and woodchuck hepatitis virus post-transcriptional regulatory element as well as antibiotic resistance to achieve optimal and homogenous transgene expression. We show that the system 1) is functional in mouse and human ES cells, 2) allows the generation of ES cells expressing genes of interest under the control of ubiquitous or tissue-specific promoters, and 3) allows ES cells expressing two constructs through selection with different antibiotics to be obtained. The technology described herein should become a useful tool in stem cell research