La violencia en la escuela : detección y prevención de conductas violentas

En las sociedades actuales, debemos reconocer que la violencia atraviesa todas las esferas, ya sea económica, social, política y cultural. Para el presente trabajo, se reconoce que las relaciones sociales son siempre relaciones de poder, y como tales, siempre se hallan en ellas condiciones de opresión, abuso de autoridad y discriminación. La violencia se presenta como un fenómeno cotidiano en las prácticas sociales, se llega a naturalizar, actuando de un modo desprevenido y sorpresivo, no sólo frente a los atentados contra la propiedad, la agresión física y simbólica que se muestra a diario en los medios masivos de comunicación, sino también en otras formas como servicios públicos deficientes, pobreza, marginalidad, adicciones, entre otros. La propuesta de este trabajo es que los docentes puedan volver visibles las prácticas violentas a las que están sujetas las relaciones sociales de sus alumnos, dentro y fuera de la escuela, reconociendo inicialmente sus propias prácticas, como posibles portadoras de violencia.Fil: De Cara, Graciela B.. Universidad Nacional de San Jua

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

AbstractObjectiveWe sought to assess whether genetic risk factors for atrial fibrillation can explain cardioembolic stroke risk.MethodsWe evaluated genetic correlations between a prior genetic study of AF and AF in the presence of cardioembolic stroke using genome-wide genotypes from the Stroke Genetics Network (N = 3,190 AF cases, 3,000 cardioembolic stroke cases, and 28,026 referents). We tested whether a previously-validated AF polygenic risk score (PRS) associated with cardioembolic and other stroke subtypes after accounting for AF clinical risk factors.ResultsWe observed strong correlation between previously reported genetic risk for AF, AF in the presence of stroke, and cardioembolic stroke (Pearson’s r=0.77 and 0.76, respectively, across SNPs with p &lt; 4.4 × 10−4 in the prior AF meta-analysis). An AF PRS, adjusted for clinical AF risk factors, was associated with cardioembolic stroke (odds ratio (OR) per standard deviation (sd) = 1.40, p = 1.45×10−48), explaining ∼20% of the heritable component of cardioembolic stroke risk. The AF PRS was also associated with stroke of undetermined cause (OR per sd = 1.07, p = 0.004), but no other primary stroke subtypes (all p &gt; 0.1).ConclusionsGenetic risk for AF is associated with cardioembolic stroke, independent of clinical risk factors. Studies are warranted to determine whether AF genetic risk can serve as a biomarker for strokes caused by AF.</jats:sec

La Enseñanza de la Sociología como aporte disciplinar a la Carrera de Diseño Industrial

La Sociología realiza aportes a disciplinas referidas al hombre; contribuye al Diseño Industrial y Gráfico con consideraciones específicas como: categorías y lógicas de pensamiento que abordan la realidad dinámica con un sentido reflexivo y crítico, de grupos sociales con necesidades y estilos de vida diferentes dentro del conjunto en general. Permite reconocer la influencia de escuelas contemporáneas y las dimensiones ocultas de sentido común dentro de un determinado contexto

GCCR003: Follow-up study on the relation between COVID-19 and long-term chemosensory loss

Preparing for the pre-registration and ensuing analysi

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes

Objective: We sought to assess whether genetic risk factors for atrial fibrillation (AF) can explain cardioembolic stroke risk. Methods: We evaluated genetic correlations between a previous genetic study of AF and AF in the presence of cardioembolic stroke using genome-wide genotypes from the Stroke Genetics Network (N = 3,190 AF cases, 3,000 cardioembolic stroke cases, and 28,026 referents). We tested whether a previously validated AF polygenic risk score (PRS) associated with cardioembolic and other stroke subtypes after accounting for AF clinical risk factors. Results: We observed a strong correlation between previously reported genetic risk for AF, AF in the presence of stroke, and cardioembolic stroke (Pearson r = 0.77 and 0.76, respectively, across SNPs with p 0.1). Conclusions: Genetic risk of AF is associated with cardioembolic stroke, independent of clinical risk factors. Studies are warranted to determine whether AF genetic risk can serve as a biomarker for strokes caused by AF.status: publishe