PROFESSIONAL COMPETENCIES AND COMPETENCIES LINKED TO SOCIO-SCIENTIFIC ISSUES IN THE BACHELOR'S DEGREE IN BIOTECHNOLOGY AT UNIVERSIDAD NACIONAL DEL LITORAL (SANTA FE, ARGENTINA): TEACHERS' PERCEPTION

En este trabajo se analiza la percepción que, sobre las competencias profesionales (CP) y las competencias vinculadas con cuestiones socio-científicas (CSC), tienen los Profesores y las Profesoras del Ciclo de Especialización (CE) de la carrera de Licenciatura en Biotecnología (LB), período 2020-2021, de la Facultad de Bioquímica y Ciencias Biológicas (FBCB) de la Universidad Nacional del Litoral (UNL), Santa Fe-Argentina. La metodología de trabajo empleada en este trabajo implicó efectuar entrevistas en profundidad, mediante videoconferencia a un grupo (n=7) de Profesores y Profesoras del CE, partiendo de la base de resultados previos que mostraban diferencias significativas entre el nivel de importancia (NI) reconocido por el profesorado para la práctica profesional de los/as graduados/as y el nivel desarrollado (ND) durante la formación universitaria, de una serie de CP y competencias vinculadas con CSC. Del análisis de  las entrevistas emergieron algunas problemáticas que los entrevistados señalan como responsables de las dificultades que determinan ND por debajo de los NI.Este artigo analisa a percepção que os professores do Ciclo de Especialização (CE) do curso de graduação em Biotecnologia têm sobre as competências profissionais (CP) e as competências relacionadas à questões sociocientíficas (QSC), no período 2020-2021, da Faculdade de Bioquímica e Ciências Biológicas (FBCB) da Universidad Nacional del Litoral (UNL), Santa Fe-Argentina. A metodologia utilizada neste estudo envolveu a realização de entrevistas em profundidade, via videoconferência, com um grupo (n=7) de professores do CE, baseadas em resultados anteriores que mostraram diferenças significativas entre o nível de importância (NI) reconhecido pelo professores para a atividade  profissional dos graduados e o nível desenvolvido (ND) durante a formação universitária, de uma série de CP e competências vinculadas às QSC. A partir da análise das entrevistas emergiram alguns problemas que os entrevistados apontam como responsáveis ​​pelas dificuldades que determinam ND abaixo da NI.  This paper analyzes the perception that the Professors of the Specialization Cycle (SC) of the Bachelor's degree in Biotechnology have about professional competencies (PC) and competencies related to socio-scientific issues (SSI), period 2020-2021, from the Faculty of Biochemistry and Biological Sciences (FBCB) of the Universidad Nacional del Litoral (UNL), Santa Fe-Argentina. The methodology used in this study involved carrying out in-depth interviews, via videoconference, with a group (n=7) of SC Teachers, based on previous results that showed significant differences between the level of importance (LI) recognized by the teaching staff for the professional practice of the graduates and the developed level (DL) during the university education, of a series of PC and competences linked to SSI. From the analysis of the interviews, some problems emerged that the interviewees point out as being responsible for the difficulties that determine DL below the LI. &nbsp

Biodiversity recovery of Neotropical secondary forests

Old-growth tropical forests harbor an immense diversity of tree species but are rapidly being cleared, while secondary forests that regrow on abandoned agricultural lands increase in extent. We assess how tree species richness and composition recover during secondary succession across gradients in environmental conditions and anthropogenic disturbance in an unprecedented multisite analysis for the Neotropics. Secondary forests recover remarkably fast in species richness but slowly in species composition. Secondary forests take a median time of five decades to recover the species richness of old-growth forest (80% recovery after 20 years) based on rarefaction analysis. Full recovery of species composition takes centuries (only 34% recovery after 20 years). A dual strategy that maintains both old-growth forests and species-rich secondary forests is therefore crucial for biodiversity conservation in human-modified tropical landscapes. Copyright © 2019 The Authors, some rights reserved

Traitement des rejets d'industries de transformation du lait par bioréacteur à membrane associant un lit fixé anaérobie et une unité d'ultrafiltration

CAEN-BU Sciences et STAPS (141182103) / SudocSudocFranceF

Analogues of Human Granulysin as Antimycobacterial Agents

Antimicrobial peptides are essential components of innate defense mechanisms and make promising candidates for novel anti-infective agents. The advantages of these peptides in clinical applications include their potential for broad-spectrum and rapid bactericidal activities, and low propensity for resistance development, whereas possible disadvantages include their high cost, limited stability, and unknown toxicology and pharmacokinetics. Granulysin (Gr) is a cytolytic and proinflammatory molecule expressed by activated human cytotoxic T lymphocytes and natural killer (NK) cells. This paper aims to study bacteriostatic and bactericidal activity against Mycobacterium tuberculosis by synthetic analogues of human Gr between 12 and 26 amino acids (AA) and their acyl derivatives. Considering results of previous studies, five new peptides were designed: a cyclic of 20 AA (Gr-SL1); one of 21 AA (linear) (Gr-SL2), another of 12 AA (cyclic) (Gr-SL3) and two lipopeptides (Gr-SL3-lauric and Gr-SL3-palmitic). Peptides were manually synthesized as C-terminal carboxamides by the solid-phase method following Fmoc chemistry. Gr synthetic analogues were purified by reverse phase HPLC and analyzed by analytical C18RP-HPLC and Maldi Tof. The antimycobacterial activity of synthesized Gr analogues was assessed using a microdilution susceptibility test as described previously. Although peptides studied here had neither higher antimycobacterial activity nor lower toxicity than analogs of human Gr previously evaluated, fresh knowledge concerning the influence of acylation and structural aspects analyzed will optimize the design of novel peptides combining the most favorable aspects for the maintenance of antimycobacterial activity with minimum toxicity.Fil: Siano, Alvaro Sebastían. Universidad Nacional del Litoral; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Tonarelli, Georgina Guadalupe. Universidad Nacional del Litoral; ArgentinaFil: Larpin, Daniel. Universidad Nacional del Litoral; ArgentinaFil: Imaz, María Susana. Instituto Nacional de Enfermedades Respiratorias Dr. Emilio Coni; ArgentinaFil: Alvarez, Claudia. Instituto Nacional de Enfermedades Respiratorias Dr. Emilio Coni; ArgentinaFil: Zerbini, Elsa Virginia. Universidad Nacional del Litoral; Argentina. Instituto Nacional de Enfermedades Respiratorias Dr. Emilio Coni; Argentin

KRACH SANITAIRE : la crise, à quel prix ?

Aujourd’hui, notre système de protection sociale est malade. Ce ne sont plus seulement les populations auxquelles une association comme Médecins du Monde apporte assistance chaque jour qui sont concernées. A côté des migrants, des sans-logements, des travailleurs du sexe ou encore des usagers de drogues, c’est de plus en plus la population générale qui rencontre des difficultés d’accès aux soins. Prendre la mesure de l’évolution de la précarité chez certaines populations, décrire les tensions et difficultés actuelles auxquelles sont exposés certains dispositifs, comme l’Aide médicale d’Etat ou le Droit au séjour pour maladie, tels sont les objectifs de ce numéro. Il réunit les représentants de structures qui assurent aujourd’hui le « filet de sécurité sociale », des observateurs de cette exclusion sanitaire montante et des acteurs qui innovent au quotidien. Avec eux, dans le contexte de crise économique et financière que nous connaissons, et alors que se dessine une tendance à l’individualisation des risques, il s’agit d’obtenir des éléments de réponse à la question qui surplombe ces problématiques : quel système de santé solidaire souhaitons-nous construire

Biodiversity recovery of Neotropical secondary forests.

Old-growth tropical forests harbor an immense diversity of tree species but are rapidly being cleared, while secondary forests that regrow on abandoned agricultural lands increase in extent. We assess how tree species richness and composition recover during secondary succession across gradients in environmental conditions and anthropogenic disturbance in an unprecedented multisite analysis for the Neotropics. Secondary forests recover remarkably fast in species richness but slowly in species composition. Secondary forests take a median time of five decades to recover the species richness of old-growth forest (80% recovery after 20 years) based on rarefaction analysis. Full recovery of species composition takes centuries (only 34% recovery after 20 years). A dual strategy that maintains both old-growth forests and species-rich secondary forests is therefore crucial for biodiversity conservation in human-modified tropical landscapes