948 research outputs found
Accelerometers can measure total and activity-specific energy expenditures in free-ranging marine mammals only if linked to time-activity budgets
Peer reviewedPostprin
The cessation in pregnancy incentives trial (CPIT): study protocol for a randomized controlled trial
Background: Seventy percent of women in Scotland have at least one baby, making pregnancy an opportunity to help most young women quit smoking before their own health is irreparably compromised. By quitting during pregnancy their infants will be protected from miscarriage and still birth as well as low birth weight, asthma, attention deficit disorder and adult cardiovascular disease. In the UK, the NICE guidelines: 'How to stop smoking in pregnancy and following childbirth' (June 2010) highlighted that little evidence exists in the literature to confirm the efficacy of financial incentives to help pregnant smokers to quit. Its first research recommendation was to determine: Within a UK context, are incentives an acceptable, effective and cost-effective way to help pregnant women who smoke to quit?
<p/>Design and Methods: This study is a phase II exploratory individually randomised controlled trial comparing standard care for pregnant smokers with standard care plus the additional offer of financial voucher incentives to engage with specialist cessation services and/or to quit smoking during pregnancy. Participants (n=600) will be pregnant smokers identified at maternity booking who when contacted by specialist cessation services agree to having their details passed to the NHS Smokefree Pregnancy Study Helpline to discuss the trial. The NHS Smokefree Pregnancy Study Helpline will be responsible for telephone consent and follow-up in late pregnancy. The primary outcome will be self reported smoking in late pregnancy verified by cotinine measurement. An economic evaluation will refine cost data collection and assess potential cost-effectiveness while qualitative research interviews with clients and health professionals will assess the level of acceptance of this form of incentive payment. Research questions What is the likely therapeutic efficacy? Are incentives potentially cost-effective? Is individual randomisation an efficient trial design without introducing outcome bias? Can incentives be introduced in a way that is feasible and acceptable?
<p/>Discussion: This phase II trial will establish a workable design to reduce the risks associated with a future definitive phase III multicentre randomised controlled trial and establish a framework to assess the costs and benefits of financial incentives to help pregnant smokers to quit
Winking at Facebook: capturing digitally-mediated classroom learning
In this article I present an innovative combination of methods, used in a study of the use of Facebook as an educational resource by five dyslexic students at a Sixth Form College in north-west England. Through a project in which teacher-researcher and student-participants co-constructed a Facebook group page about the students’ scaffolded research into dyslexia, the study examined the educational affordances of a digitally-mediated social network. Combining multiple data-collection methods including participant-observation, semi-structured interviews, video recordings, dynamic screen capture (Cox, 2007), protocol analysis (Ericsson & Simon, 1993) helped to capture in detail multiple perspectives on the learning that happened in the classroom over the five weeks of the research project's lifetime. Aggregating the resulting data in turn enabled meticulous, comprehensive analysis and rigorous theorising. The article presents and analyses excerpts from the data which help to illustrate the insights gained into one participant's learning trajectory. I argue that the combination of methods employed could be used with any range of research participants in other studies exploring learning through Facebook and other Web 2.0 spaces. The article concludes by suggesting further refinements to the methods used
Pervasive sensing to model political opinions in face-to-face networks
Exposure and adoption of opinions in social networks are
important questions in education, business, and government. We de-
scribe a novel application of pervasive computing based on using mobile
phone sensors to measure and model the face-to-face interactions and
subsequent opinion changes amongst undergraduates, during the 2008
US presidential election campaign. We nd that self-reported political
discussants have characteristic interaction patterns and can be predicted
from sensor data. Mobile features can be used to estimate unique individ-
ual exposure to di erent opinions, and help discover surprising patterns
of dynamic homophily related to external political events, such as elec-
tion debates and election day. To our knowledge, this is the rst time
such dynamic homophily e ects have been measured. Automatically esti-
mated exposure explains individual opinions on election day. Finally, we
report statistically signi cant di erences in the daily activities of individ-
uals that change political opinions versus those that do not, by modeling
and discovering dominant activities using topic models. We nd people
who decrease their interest in politics are routinely exposed (face-to-face)
to friends with little or no interest in politics.U.S. Army Research Laboratory (Cooperative Agreement No. W911NF-09-2-0053)United States. Air Force Office of Scientific Research (Award No. FA9550-10-1-0122)Swiss National Science Foundatio
Using social network sites in Higher Education: An experience in business studies
In the past 5 years the impact of Web 2.0 in new generations has been remarkably significant (Pew Research Center, 2010). This paper reports on an experience in the use of Social Network Sites (SNS) to support student involvement with the subject and to develop basic skills.
According to students’ opinion, the experience was deemed as positive. They considered that the experience contributed to a higher engagement with the subject and a deeper collaboration with other students and teaching staff. As a result, the majority of students would prefer the use of SNS as a first option if they had to enrol again in the subject.
Regarding the relationships between academic performance and use of the SNS, two different student profiles were identified based on usage patterns of the platform. Students with a more intensive use of the site showed a significantly better performance than students with a low usage profile.This work was partially supported by the Junta de Andalucía – FEDER (Proyectos de Excelencia: SEJ-02670
Motivators of online vulnerability: the impact of social network site use and FOMO
Continued and frequent use of social network sites (SNS) has been linked to a fear of missing out (FOMO) and online self-promotion in the form of friending and information disclosure. The present paper reports findings from 506 UK based Facebook users (53% male) who responded to an extensive online survey about their SNS behaviours and online vulnerability. Structural equation modelling (SEM) suggests that FOMO mediates the relationship between increased SNS use and decreased self-esteem. Self-promoting SNS behaviours provide more complex mediated associations. Longitudinal support (N = 175) is provided for the notion that decreased self-esteem might motivate a potentially detrimental cycle of FOMO-inspired online SNS use. The research considers the implications of social networking on an individual’s online vulnerability
GC-MS Techniques Investigating Potential Biomarkers of Dying in the Last Weeks with Lung Cancer
Predicting when a patient with advanced cancer is dying is a challenge and currently no prognostic test is available. We hypothesised that a dying process from cancer is associated with metabolic changes and specifically with changes in volatile organic compounds (VOCs). We analysed urine from patients with lung cancer in the last weeks of life by headspace gas chromatography mass spectrometry. Urine was acidified or alkalinised before analysis. VOC changes in the last weeks of life were identified using univariate, multivariate and linear regression analysis; 12 VOCs increased (11 from the acid dataset, 2 from the alkali dataset) and 25 VOCs decreased (23 from the acid dataset and 3 from the alkali dataset). A Cox Lasso prediction model using 8 VOCs predicted dying with an AUC of 0.77, 0.78 and 0.85 at 30, 20 and 10 days and stratified patients into a low (median 10 days), medium (median 50 days) or high risk of survival. Our data supports the hypothesis there are specific metabolic changes associated with the dying. The VOCs identified are potential biomarkers of dying in lung cancer and could be used as a tool to provide additional prognostic information to inform expert clinician judgement and subsequent decision making
Semantic Web Tools and Decision-Making
Semantic Web technologies are intertwined with decision-making
processes. In this paper the general objectives of the semantic web tools are reviewed
and characterized, as well as the categories of decision support tools, in
order to establish an intersection of utility and use. We also elaborate on actual
and foreseen possibilities for a deeper integration, considering the actual implementation,
opportunities and constraints in the decision-making context.info:eu-repo/semantics/publishedVersio
VERTIGO (VERtical Transport In the Global Ocean) : a study of particle sources and flux attenuation in the North Pacific
Author Posting. © Elsevier B.V., 2008. This is the author's version of the work. It is posted here by permission of Elsevier B.V. for personal use, not for redistribution. The definitive version was published in Deep Sea Research Part II: Topical Studies in Oceanography 55 (2008): 1522-1539, doi:10.1016/j.dsr2.2008.04.024.The VERtical Transport In the Global Ocean (VERTIGO) study examined particle sources and
fluxes through the ocean’s “twilight zone” (defined here as depths below the euphotic zone to
1000 m). Interdisciplinary process studies were conducted at contrasting sites off Hawaii
(ALOHA) and in the NW Pacific (K2) during 3 week occupations in 2004 and 2005, respectively.
We examine in this overview paper the contrasting physical, chemical and biological settings and
how these conditions impact the source characteristics of the sinking material and the transport
efficiency through the twilight zone. A major finding in VERTIGO is the considerably lower
transfer efficiency (Teff) of particulate organic carbon (POC), POC flux 500 / 150 m, at ALOHA
(20%) vs. K2 (50%). This efficiency is higher in the diatom-dominated setting at K2 where
silica-rich particles dominate the flux at the end of a diatom bloom, and where zooplankton and
their pellets are larger. At K2, the drawdown of macronutrients is used to assess export and
suggests that shallow remineralization above our 150 m trap is significant, especially for N
relative to Si. We explore here also surface export ratios (POC flux/primary production) and
possible reasons why this ratio is higher at K2, especially during the first trap deployment. When
we compare the 500 m fluxes to deep moored traps, both sites lose about half of the sinking POC
by >4000 m, but this comparison is limited in that fluxes at depth may have both a local and
distant component. Certainly, the greatest difference in particle flux attenuation is in the
mesopelagic, and we highlight other VERTIGO papers that provide a more detailed examination
of the particle sources, flux and processes that attenuate the flux of sinking particles. Ultimately,
we contend that at least three types of processes need to be considered: heterotrophic degradation
of sinking particles, zooplankton migration and surface feeding, and lateral sources of suspended
and sinking materials. We have evidence that all of these processes impacted the net attenuation
of particle flux vs. depth measured in VERTIGO and would therefore need to be considered and
quantified in order to understand the magnitude and efficiency of the ocean’s biological pump.Funding for VERTIGO was provided primarily by research grants
from the US National Science Foundation Programs in Chemical and Biological Oceanography
(KOB, CHL, MWS, DKS, DAS). Additional US and non-US grants included: US Department
of Energy, Office of Science, Biological and Environmental Research Program (JKBB); the
Gordon and Betty Moore Foundation (DMK); the Australian Cooperative Research Centre
program and Australian Antarctic Division (TWT); Chinese NSFC and MOST programs (NZJ);
Research Foundation Flanders and Vrije Universiteit Brussel (FD, ME); JAMSTEC (MCH); New
Zealand Public Good Science Foundation (PWB); and internal WHOI sources and a contribution
from the John Aure and Cathryn Ann Hansen Buesseler Foundation (KOB)
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