1,301 research outputs found
Runaway Events Dominate the Heavy Tail of Citation Distributions
Statistical distributions with heavy tails are ubiquitous in natural and
social phenomena. Since the entries in heavy tail have disproportional
significance, the knowledge of its exact shape is very important. Citations of
scientific papers form one of the best-known heavy tail distributions. Even in
this case there is a considerable debate whether citation distribution follows
the log-normal or power-law fit. The goal of our study is to solve this debate
by measuring citation distribution for a very large and homogeneous data. We
measured citation distribution for 418,438 Physics papers published in
1980-1989 and cited by 2008. While the log-normal fit deviates too strong from
the data, the discrete power-law function with the exponent does
better and fits 99.955% of the data. However, the extreme tail of the
distribution deviates upward even from the power-law fit and exhibits a
dramatic "runaway" behavior. The onset of the runaway regime is revealed
macroscopically as the paper garners 1000-1500 citations, however the
microscopic measurements of autocorrelation in citation rates are able to
predict this behavior in advance.Comment: 6 pages, 5 Figure
Thermoelectric Response of an Interacting Two-Dimensional Electron Gas in Quantizing Magnetic Field
We present a discussion of the linear thermoelectric response of an
interacting electron gas in a quantizing magnetic field. Boundary currents can
carry a significant fraction of the net current passing through the system. We
derive general expressions for the bulk and boundary components of the number
and energy currents. We show that the local current density may be described in
terms of ``transport'' and ``internal magnetization'' contributions. The latter
carry no net current and are not observable in standard transport experiments.
We show that although Onsager relations cannot be applied to the local current,
they are valid for the transport currents and hence for the currents observed
in standard transport experiments. We relate three of the four thermoelectric
response coefficients of a disorder-free interacting two-dimensional electron
gas to equilibrium thermodynamic quantities. In particular, we show that the
diffusion thermopower is proportional to the entropy per particle, and we
compare this result with recent experimental observations.Comment: 18 pages, 2 postscript figures included. Revtex with epsf.tex and
multicol.sty. In the revised version, the comparison with experimental
observations at is extended to include the possibility of
corrections due to weak impurity scattering. The conclusions that we reach
regarding the applicability of the composite fermion model at these filling
fractions are not affecte
The Case for a Sociology of Dying, Death and Bereavement
YesDying, death and bereavement do not occur in a social vacuum. How individuals and groups experience these phenomena will be largely influenced by the social context in which they occur. To develop an adequate understanding of dying, death and bereavement we therefore need to incorporate a sociological perspective into our analysis. This paper examines why a sociological perspective is necessary and explores various ways in which sociology can be of practical value in both intellectual and professional contexts. A case study comparing psychological and sociological perspectives is offered by way of illustration
Bereavement and the role of religious and cultural factors.
yesThe aim of this article is to give an overview of some of the key dimensions of variation in cultural and religious rituals during the immediate period after a death and in the longer term, in order to inform service delivery in multi-cultural societies. For each area we give examples of different customs, and consider their functions and possible impact. Dimensions considered in the immediate period after bereavement are: The time and space given to formal rituals, expression of feelings, assertion of status and disposal of the body. In the longer term, we look at variations in remembering the deceased and in continuing bonds. Throughout we consider the interplay between individual responses and the person¿s cultural and religious context. Our objective is to provide an accessible introduction for practitioners new to working with bereavement and provide a succinct reference point for more experienced bereavement workers.Full text made available 1st May 2014 at the end of the publisher's embargo period
Mycorrhizas and biomass crops: opportunities for future sustainable development
Central to soil health and plant productivity in natural ecosystems are in situ soil microbial communities, of which mycorrhizal fungi are an integral component, regulating nutrient transfer between plants and the surrounding soil via extensive mycelial networks. Such networks are supported by plant-derived carbon and are likely to be enhanced under coppiced biomass plantations, a forestry practice that has been highlighted recently as a viable means of providing an alternative source of energy to fossil fuels, with potentially favourable consequences for carbon mitigation. Here, we explore ways in which biomass forestry, in conjunction with mycorrhizal fungi, can offer a more holistic approach to addressing several topical environmental issues, including ‘carbon-neutral’ energy, ecologically sustainable land management and CO2 sequestration
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Transforming bonds: ritualising post-mortem relationships in the Netherlands
People continue relationships with their dead in a variety of ways. Since the 1990s, the idea of ‘continuing bonds’ has provided a framework for exploring and understanding post-mortem relationships. However, the dynamics of the bonds between the living and the dead have received little attention. By looking at the intersection of things, practices and spaces, this paper demonstrates that expressions of continuing bonds do not always point to continuity, and indeed can signify discontinuity. It explores the ‘transforming bonds’ between the recently bereaved and their deceased in the Netherlands, illustrating how post-mortem relationships change and how such changes affect the social location of the deceased and the bereaved. By attending to the ritual dynamics of separation, transition and integration, two aspects of the social and material relationships between the living and the dead are highlighted. First, attention is given to the ways wherein the bereaved relocate their deceased through material objects within and outside of their homes, enabling them to renegotiate the absence–presence of the deceased. Second, the paper illustrates that personalised incorporation practices are inevitably linked to negotiations and contestations in the social sphere, and the norms and values of the social environment
The Highly Energetic Expansion of SN2010bh Associated with GRB 100316D
We present the spectroscopic and photometric evolution of the nearby (z =
0.059) spectroscopically confirmed type Ic supernova, SN 2010bh, associated
with the soft, long-duration gamma-ray burst (X-ray flash) GRB 100316D.
Intensive follow-up observations of SN 2010bh were performed at the ESO Very
Large Telescope (VLT) using the X-shooter and FORS2 instruments. Owing to the
detailed temporal coverage and the extended wavelength range (3000--24800 A),
we obtained an unprecedentedly rich spectral sequence among the hypernovae,
making SN 2010bh one of the best studied representatives of this SN class. We
find that SN 2010bh has a more rapid rise to maximum brightness (8.0 +/- 1.0
rest-frame days) and a fainter absolute peak luminosity (L_bol~3e42 erg/s) than
previously observed SN events associated with GRBs. Our estimate of the ejected
(56)Ni mass is 0.12 +/- 0.02 Msun. From the broad spectral features we measure
expansion velocities up to 47,000 km/s, higher than those of SNe 1998bw (GRB
980425) and 2006aj (GRB 060218). Helium absorption lines He I lambda5876 and He
I 1.083 microm, blueshifted by ~20,000--30,000 km/s and ~28,000--38,000 km/s,
respectively, may be present in the optical spectra. However, the lack of
coverage of the He I 2.058 microm line prevents us from confirming such
identifications. The nebular spectrum, taken at ~186 days after the explosion,
shows a broad but faint [O I] emission at 6340 A. The light-curve shape and
photospheric expansion velocities of SN 2010bh suggest that we witnessed a
highly energetic explosion with a small ejected mass (E_k ~ 1e52 erg and M_ej ~
3 Msun). The observed properties of SN 2010bh further extend the heterogeneity
of the class of GRB supernovae.Comment: 37 pages and 12 figures (one-column pre-print format), accepted for
publication in Ap
Hormonal Signal Amplification Mediates Environmental Conditions during Development and Controls an Irreversible Commitment to Adulthood
Many animals can choose between different developmental fates to maximize fitness. Despite the complexity of environmental cues and life history, different developmental fates are executed in a robust fashion. The nematode Caenorhabditis elegans serves as a powerful model to examine this phenomenon because it can adopt one of two developmental fates (adulthood or diapause) depending on environmental conditions. The steroid hormone dafachronic acid (DA) directs development to adulthood by regulating the transcriptional activity of the nuclear hormone receptor DAF-12. The known role of DA suggests that it may be the molecular mediator of environmental condition effects on the developmental fate decision, although the mechanism is yet unknown. We used a combination of physiological and molecular biology techniques to demonstrate that commitment to reproductive adult development occurs when DA levels, produced in the neuroendocrine XXX cells, exceed a threshold. Furthermore, imaging and cell ablation experiments demonstrate that the XXX cells act as a source of DA, which, upon commitment to adult development, is amplified and propagated in the epidermis in a DAF-12 dependent manner. This positive feedback loop increases DA levels and drives adult programs in the gonad and epidermis, thus conferring the irreversibility of the decision. We show that the positive feedback loop canalizes development by ensuring that sufficient amounts of DA are dispersed throughout the body and serves as a robust fate-locking mechanism to enforce an organism-wide binary decision, despite noisy and complex environmental cues. These mechanisms are not only relevant to C. elegans but may be extended to other hormonal-based decision-making mechanisms in insects and mammals
Phenotypic covariance of longevity, immunity and stress resistance in the Caenorhabditis nematodes
Background \ud
Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin– like growth factor signalling (IIS) pathway. In the nematode Caenorhabditis elegans, these phenotypes are molecularly linked such that activation of the forkhead transcription factor DAF-16 both extends lifespan and simultaneously increases immunity and stress resistance. It is known that lifespan varies significantly among the Caenorhabditis species but, although DAF-16 signalling is highly conserved, it is unclear whether this phenotypic linkage occurs in other species. Here we investigate this phenotypic covariance by comparing longevity, stress resistance and immunity in four \ud
Caenorhabditis species. \ud
\ud
Methodology/Principal Findings \ud
We show using phenotypic analysis of DAF-16 influenced phenotypes that among four closely related Caenorhabditis nematodes, the gonochoristic species (Caenorhabditis remanei and Caenorhabditis brenneri) have diverged \ud
significantly with a longer lifespan, improved stress resistance and higher immunity than the hermaphroditic species (C. elegans and Caenorhabditis briggsae). Interestingly, we also observe significant differences in expression levels between the daf-16 homologues in these species using Real-Time PCR, which positively correlate with the observed phenotypes. Finally, we provide additional evidence in support of a role for DAF-16 in regulating phenotypic coupling by using a combination of wildtype isolates, constitutively active daf-16 mutants and bioinformatic analysis. \ud
\ud
Conclusions \ud
The gonochoristic species display a significantly longer lifespan (p < 0.0001)and more robust immune and stress response (p<0.0001, thermal stress; p<0.01, heavy metal stress; p<0.0001, pathogenic stress) than the hermaphroditic species. Our data suggests that divergence in DAF-16 mediated phenotypes may underlie many of the differences observed between these four species of Caenorhabditis nematodes. These findings are further supported by the correlative higher daf-16 expression levels among the gonochoristic species and significantly higher lifespan, immunity and stress tolerance in the constitutively active daf-16 hermaphroditic mutants
A Small Conductance Calcium-Activated K<sup>+</sup> Channel in C. elegans, KCNL-2, Plays a Role in the Regulation of the Rate of Egg-Laying
In the nervous system of mice, small conductance calcium-activated potassium (SK) channels function to regulate neuronal excitability through the generation of a component of the medium afterhyperpolarization that follows action potentials. In humans, irregular action potential firing frequency underlies diseases such as ataxia, epilepsy, schizophrenia and Parkinson's disease. Due to the complexity of studying protein function in the mammalian nervous system, we sought to characterize an SK channel homologue, KCNL-2, in C. elegans, a genetically tractable system in which the lineage of individual neurons was mapped from their early developmental stages. Sequence analysis of the KCNL-2 protein reveals that the six transmembrane domains, the potassium-selective pore and the calmodulin binding domain are highly conserved with the mammalian homologues. We used widefield and confocal fluorescent imaging to show that a fusion construct of KCNL-2 with GFP in transgenic lines is expressed in the nervous system of C. elegans. We also show that a KCNL-2 null strain, kcnl-2(tm1885), demonstrates a mild egg-laying defective phenotype, a phenotype that is rescued in a KCNL-2-dependent manner. Conversely, we show that transgenic lines that overexpress KCNL-2 demonstrate a hyperactive egg-laying phenotype. In this study, we show that the vulva of transgenic hermaphrodites is highly innervated by neuronal processes and by the VC4 and VC5 neurons that express GFP-tagged KCNL-2. We propose that KCNL-2 functions in the nervous system of C. elegans to regulate the rate of egg-laying. © 2013 Chotoo et al
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