Secular and Religious Responses to a Child's Potentially Fatal Illness in the Canary Islands

In the summer of 1985 two-year-old Lucia, the only child of my friends on the island of Tenerife, Lourdes and Eligio, went cross-eyed. After she was given corrective glasses, and then had an operation, she began to have dizzy spells and be unsteady on her feet. Finally in February, 1986, after a bad fall and vomiting, she was taken to a hospital, where a large tumor was found in her brain. She was immediately operated on, and a valve was installed to relieve the pressure on the brain, pending the more complex removal of the tumor. The doctors were pessimistic. They said the chances were 95% that the tumor was malignant; that Lucia might not survive its removal, and that if she did her life would probably be short and unpleasant.

Decline of Spectacled Eiders Nesting in Western Alaska

Spectacled eider (Somateria fischeri) populations in western Alaska are now less than 4% of the numbers estimated in the early 1970s. In 1992, an estimated 1721 nesting pairs remained on the Yukon-Kuskokwim Delta. Causes of this rapid and continuing decline of -14% per year are undocumented. Many aspects of spectacled eider biology remain unknown, including their marine foraging habitats, food items, migratory movements, and population ecology. A review of some biological characteristics and possible threats to the species suggests the importance of quantifying potential impacts from parasites and disease, subsistence harvest, predation during brood rearing, and alteration of Bering Sea food resources. Factors causing the population decline of spectacled eiders must be determined and appropriate actions taken to reverse the trend.Key words: Alaska, declining species, Somateria fischeri, spectacled eider, waterfowl, Yukon-Kuskokwim DeltaLes populations d'eider à lunettes (Somateria fischeri) de l'Alaska occidental s'élèvent maintenant à moins de 4 p. cent du total estimé au début des années 70. En 1992, on a estimé à 1721 le nombre de paires nicheuses qui restaient dans le delta du Yukon-Kuskokwim. Les causes de ce déclin rapide et continu de -14 p. cent par an ne sont pas documentées. Bien des aspects de la biologie de l'eider à lunettes restent inconnus, y compris l'habitat marin où il trouve sa nourriture, ses aliments, ses déplacements migratoires et l'écologie de la population. Un examen de certaines caractéristiques biologiques et des menaces dont l'espèce pourrait faire l'objet suggère l'importance qu'il y a à quantifier les retombées potentielles des parasites et des maladies, des récoltes destinées à assurer la subsistance, de la prédation durant l'élevage de la couvée et des changements dans les ressources alimentaires de la mer de Béring. Il faut déterminer les facteurs responsables du déclin de la population de l'eider à lunettes et prendre les mesures qui s'imposent pour renverser la tendance.Mots clés : Alaska, espèce en déclin, Somateria fischeri, eider à lunettes, oiseau aquatique, delta du Yukon-Kuskokwi

Spinal involvement in mucopolysaccharidosis IVA (Morquio-Brailsford or Morquio A syndrome): presentation, diagnosis and management.

Mucopolysaccharidosis IVA (MPS IVA), also known as Morquio-Brailsford or Morquio A syndrome, is a lysosomal storage disorder caused by a deficiency of the enzyme N-acetyl-galactosamine-6-sulphate sulphatase (GALNS). MPS IVA is multisystemic but manifests primarily as a progressive skeletal dysplasia. Spinal involvement is a major cause of morbidity and mortality in MPS IVA. Early diagnosis and timely treatment of problems involving the spine are critical in preventing or arresting neurological deterioration and loss of function. This review details the spinal manifestations of MPS IVA and describes the tools used to diagnose and monitor spinal involvement. The relative utility of radiography, computed tomography (CT) and magnetic resonance imaging (MRI) for the evaluation of cervical spine instability, stenosis, and cord compression is discussed. Surgical interventions, anaesthetic considerations, and the use of neurophysiological monitoring during procedures performed under general anaesthesia are reviewed. Recommendations for regular radiological imaging and neurologic assessments are presented, and the need for a more standardized approach for evaluating and managing spinal involvement in MPS IVA is addressed

Relationship between cardiovascular risk factors and biomarkers with necrotic core and atheroma size: a serial intravascular ultrasound radiofrequency data analysis

We explored the impact of patient demographics, anthropometric measurements, cardiovascular risk factors, and soluble biomarkers on necrotic core and atheroma size in patients with coronary disease. The IBIS-2 trial enrolled 330 patients. In the multivariate analysis, at baseline, creatinine had a positive, whereas baseline mean lumen diameter and myeloperoxidase had a negative, independent association with percentage of necrotic core (PNC); while age, glomerular filtration rate <60, HbA1c, previous PCI or CABG and baseline % diameter stenosis were positively, and acute coronary syndromes (ACS) were negatively associated with baseline percentage atheroma volume (PAV). The variables associated with a decrease in PNC from baseline were darapladib, ACS and a large content of NC at baseline, while variables associated with an increase in PNC were previous stroke and % diameter stenosis at baseline. Those variables associated with a decrease in PAV from baseline were waist circumference, statin use, CD40L and baseline PAV, while the only variable associated with an increase in PAV was baseline diastolic blood pressure. Treatment with darapladib was associated with a decrease in necrotic core, but was not associated with a decrease in percentage atheroma volume. On the contrary, statin use was only associated with a decrease in percentage atheroma volume

Communication Biophysics

Contains reports on six research projects.National Institutes of Health (Grant 5 PO1 NS13126)National Institutes of Health (Grant 5 RO1 NS18682)National Institutes of Health (Grant 5 RO1 NS20322)National Institutes of Health (Grant 5 R01 NS20269)National Institutes of Health (Grant 5 T32NS 07047)Symbion, Inc.National Science Foundation (Grant BNS 83-19874)National Science Foundation (Grant BNS 83-19887)National Institutes of Health (Grant 6 RO1 NS 12846)National Institutes of Health (Grant 1 RO1 NS 21322

The Fourteenth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the extended Baryon Oscillation Spectroscopic Survey and from the second phase of the Apache Point Observatory Galactic Evolution Experiment

The fourth generation of the Sloan Digital Sky Survey (SDSS-IV) has been in operation since July 2014. This paper describes the second data release from this phase, and the fourteenth from SDSS overall (making this, Data Release Fourteen or DR14). This release makes public data taken by SDSS-IV in its first two years of operation (July 2014-2016). Like all previous SDSS releases, DR14 is cumulative, including the most recent reductions and calibrations of all data taken by SDSS since the first phase began operations in 2000. New in DR14 is the first public release of data from the extended Baryon Oscillation Spectroscopic Survey (eBOSS); the first data from the second phase of the Apache Point Observatory (APO) Galactic Evolution Experiment (APOGEE-2), including stellar parameter estimates from an innovative data driven machine learning algorithm known as "The Cannon"; and almost twice as many data cubes from the Mapping Nearby Galaxies at APO (MaNGA) survey as were in the previous release (N = 2812 in total). This paper describes the location and format of the publicly available data from SDSS-IV surveys. We provide references to the important technical papers describing how these data have been taken (both targeting and observation details) and processed for scientific use. The SDSS website (www.sdss.org) has been updated for this release, and provides links to data downloads, as well as tutorials and examples of data use. SDSS-IV is planning to continue to collect astronomical data until 2020, and will be followed by SDSS-V.Comment: SDSS-IV collaboration alphabetical author data release paper. DR14 happened on 31st July 2017. 19 pages, 5 figures. Accepted by ApJS on 28th Nov 2017 (this is the "post-print" and "post-proofs" version; minor corrections only from v1, and most of errors found in proofs corrected