Graphene plasmonics: A platform for strong light-matter interaction

Graphene plasmons provide a suitable alternative to noble-metal plasmons because they exhibit much larger confinement and relatively long propagation distances, with the advantage of being highly tunable via electrostatic gating. We report strong light- matter interaction assisted by graphene plasmons, and in particular, we predict unprecedented high decay rates of quantum emitters in the proximity of a carbon sheet, large vacuum Rabi splitting and Purcell factors, and extinction cross sections exceeding the geometrical area in graphene ribbons and nanometer-sized disks. Our results provide the basis for the emerging and potentially far-reaching field of graphene plasmonics, offering an ideal platform for cavity quantum electrodynamics and supporting the possibility of single-molecule, single-plasmon devices.Comment: 39 pages, 15 figure

Root canal treatment of maxillary incisors with heterotopic alterations: clinical case report

Aim: Cleft lip and cleft palate are the most common congenital craniofacial malformations. Dentistry plays an important role in the treatment of these patients since this defect comes associated with dental problems. Those alterations can implicate the teeth dimensions, morphology, location, quantity and structure. The endodontic strategy in teeth with challenging locations in the dental arch is a distinctive and major challenge both for diagnostics and treatment. In many situations, technical complications may lead to failure. The aim of this study is to describe particular peculiarities of root canal procedure in a special case which the patient presented location and dental alterations in maxillary incisors. This condition requires some modifications on the conventional endodontic therapy. An incorrect dental position and the presence of orthodontic appliances can contribute to the overlapping images throughout the radiographic procedures. The endodontic treatment planning of the endodontic case was examined through periapical radiographs and cone beam computed tomography. The endodontic access cavity was developed by the buccal surface due to the encountered difficulties by the intrusion and palatal direction of the anterior dental elements in the maxillary arch. The following operative endodontic steps as chemico-mechanical preparation and obturation were performed and considered satisfactory. In the obturation proceeding was employed a biological controlled technique with active lateral condensation. Conclusion: The planning stage of the treatment based on careful clinical examination and adequate complementary diagnostics procedures is essential for the endodontic treatment success of teeth with heterotopic alterations

The systemic lupus erythematosus IRF5 risk haplotype is associated with systemic sclerosis

Systemic sclerosis (SSc) is a fibrotic autoimmune disease in which the genetic component plays an important role. One of the strongest SSc association signals outside the human leukocyte antigen (HLA) region corresponds to interferon (IFN) regulatory factor 5 (IRF5), a major regulator of the type I IFN pathway. In this study we aimed to evaluate whether three different haplotypic blocks within this locus, which have been shown to alter the protein function influencing systemic lupus erythematosus (SLE) susceptibility, are involved in SSc susceptibility and clinical phenotypes. For that purpose, we genotyped one representative single-nucleotide polymorphism (SNP) of each block (rs10488631, rs2004640, and rs4728142) in a total of 3,361 SSc patients and 4,012 unaffected controls of Caucasian origin from Spain, Germany, The Netherlands, Italy and United Kingdom. A meta-analysis of the allele frequencies was performed to analyse the overall effect of these IRF5 genetic variants on SSc. Allelic combination and dependency tests were also carried out. The three SNPs showed strong associations with the global disease (rs4728142: P = 1.34×10<sup>−8</sup>, OR = 1.22, CI 95% = 1.14–1.30; rs2004640: P = 4.60×10<sup>−7</sup>, OR = 0.84, CI 95% = 0.78–0.90; rs10488631: P = 7.53×10<sup>−20</sup>, OR = 1.63, CI 95% = 1.47–1.81). However, the association of rs2004640 with SSc was not independent of rs4728142 (conditioned P = 0.598). The haplotype containing the risk alleles (rs4728142*A-rs2004640*T-rs10488631*C: P = 9.04×10<sup>−22</sup>, OR = 1.75, CI 95% = 1.56–1.97) better explained the observed association (likelihood P-value = 1.48×10<sup>−4</sup>), suggesting an additive effect of the three haplotypic blocks. No statistical significance was observed in the comparisons amongst SSc patients with and without the main clinical characteristics. Our data clearly indicate that the SLE risk haplotype also influences SSc predisposition, and that this association is not sub-phenotype-specific

The complex and spatially diverse patterns of hydrological droughts across Europe

This study presents a new data set of gauged streamflow (N = 3,224) for Europe spanning the period 1962–2017. The Monthly Streamflow of Europe Dataset (MSED) is freely available at http://msed.csic.es/. Based on this data set, changes in the characteristics of hydrological drought (i.e., frequency, duration, and severity) were assessed for different regions of Europe. Due to the density of the database, it is possible to delimit spatial patterns in hydrological droughts trend with the greatest detail available to date. Results reveal bidirectional changes in monthly streamflow, with negative changes predominating over central and southern Europe, while positive trends dominate over northern Europe. Temporally, two dominant patterns were noted. The first pattern corresponds to a consistent downward trend in all months, evident for southern Europe. A second pattern was noted over central and northern Europe and western France, with a predominant negative trend during warm months and a positive trend in cold months. For hydrological drought events, results suggest a positive trend toward more frequent and severe droughts in southern and central Europe and conversely a negative trend over northern Europe. This study emphasizes that hydrological droughts show complex spatial patterns across Europe over the past six decades, implying that hydrological drought behavior in Europe has a regional character. Accordingly it is challenging to adopt “efficient” strategies and policies to monitor and mitigate drought impacts at the continental level

Root canal treatment of maxillary incisors with heterotopic alterations: clinical case report

Aim: Cleft lip and cleft palate are the most common congenital craniofacial malformations. Dentistry plays an important role in the treatment of these patients since this defect comes associated with dental problems. Those alterations can implicate the teeth dimensions, morphology, location, quantity and structure. The endodontic strategy in teeth with challenging locations in the dental arch is a distinctive and major challenge both for diagnostics and treatment. In many situations, technical complications may lead to failure. The aim of this study is to describe particular peculiarities of root canal procedure in a special case which the patient presented location and dental alterations in maxillary incisors. This condition requires some modifications on the conventional endodontic therapy. An incorrect dental position and the presence of orthodontic appliances can contribute to the overlapping images throughout the radiographic procedures. The endodontic treatment planning of the endodontic case was examined through periapical radiographs and cone beam computed tomography. The endodontic access cavity was developed by the buccal surface due to the encountered difficulties by the intrusion and palatal direction of the anterior dental elements in the maxillary arch. The following operative endodontic steps as chemico-mechanical preparation and obturation were performed and considered satisfactory. In the obturation proceeding was employed a biological controlled technique with active lateral condensation. Conclusion: The planning stage of the treatment based on careful clinical examination and adequate complementary diagnostics procedures is essential for the endodontic treatment success of teeth with heterotopic alterations

Neuronal circuitry for pain processing in the dorsal horn

Neurons in the spinal dorsal horn process sensory information, which is then transmitted to several brain regions, including those responsible for pain perception. The dorsal horn provides numerous potential targets for the development of novel analgesics and is thought to undergo changes that contribute to the exaggerated pain felt after nerve injury and inflammation. Despite its obvious importance, we still know little about the neuronal circuits that process sensory information, mainly because of the heterogeneity of the various neuronal components that make up these circuits. Recent studies have begun to shed light on the neuronal organization and circuitry of this complex region

Measurement of branching ratio and Bs0 lifetime in the decay Bs0 -> J/psi f0(980) at CDF

We present a study of Bs0 decays to the CP-odd final state J/psi f0(980) with J/psi -> mu+ mu- and f0(980) -> pi+ pi-. Using ppbar collision data with an integrated luminosity of 3.8/fb collected by the CDF II detector at the Tevatron we measure a Bs0 lifetime of tau(Bs0 -> J/psi f0(980)) = 1.70 -0.11+0.12(stat) +-0.03(syst) ps. This is the first measurement of the Bs0 lifetime in a decay to a CP eigenstate and corresponds in the standard model to the lifetime of the heavy Bs0 eigenstate. We also measure the product of branching fractions of Bs0 -> J/psi f0(980) and f0(980) -> pi+ pi- relative to the product of branching fractions of Bs0 -> J/psi phi and phi -> K+ K- to be R_f0/phi = 0.257 +_0.020(stat) +-0.014(syst), which is the most precise determination of this quantity to date.Comment: accepted by Phys. Rev.

Evidence for t\bar{t}\gamma Production and Measurement of \sigma_t\bar{t}\gamma / \sigma_t\bar{t}

Using data corresponding to 6.0/fb of ppbar collisions at sqrt(s) = 1.96 TeV collected by the CDF II detector, we present a cross section measurement of top-quark pair production with an additional radiated photon. The events are selected by looking for a lepton, a photon, significant transverse momentum imbalance, large total transverse energy, and three or more jets, with at least one identified as containing a b quark. The ttbar+photon sample requires the photon to have 10 GeV or more of transverse energy, and to be in the central region. Using an event selection optimized for the ttbar+photon candidate sample we measure the production cross section of, and the ratio of cross sections of the two samples. Control samples in the dilepton+photon and lepton+photon+\met, channels are constructed to aid in decay product identification and background measurements. We observe 30 ttbar+photon candidate events compared to the standard model expectation of 26.9 +/- 3.4 events. We measure the ttbar+photon cross section to be 0.18+0.08 pb, and the ratio of the cross section of ttbar+photon to ttbar to be 0.024 +/- 0.009. Assuming no ttbar+photon production, we observe a probability of 0.0015 of the background events alone producing 30 events or more, corresponding to 3.0 standard deviations.Comment: 9 pages, 3 figure

Precision Top-Quark Mass Measurements at CDF

We present a precision measurement of the top-quark mass using the full sample of Tevatron $\sqrt{s}=1.96$ TeV proton-antiproton collisions collected by the CDF II detector, corresponding to an integrated luminosity of 8.7 $fb^{-1}$. Using a sample of $t\bar{t}$ candidate events decaying into the lepton+jets channel, we obtain distributions of the top-quark masses and the invariant mass of two jets from the $W$ boson decays from data. We then compare these distributions to templates derived from signal and background samples to extract the top-quark mass and the energy scale of the calorimeter jets with {\it in situ} calibration. The likelihood fit of the templates from signal and background events to the data yields the single most-precise measurement of the top-quark mass, \mtop = 172.85 \pm$0.71 (stat)$\pm$0.85 (syst) GeV/c^{2}.$Comment: submitted to Phys. Rev. Let

Search for the Higgs boson in events with missing transverse energy and b quark jets produced in proton-antiproton collisions at s**(1/2)=1.96 TeV

We search for the standard model Higgs boson produced in association with an electroweak vector boson in events with no identified charged leptons, large imbalance in transverse momentum, and two jets where at least one contains a secondary vertex consistent with the decay of b hadrons. We use ~1 fb-1 integrated luminosity of proton-antiproton collisions at s**(1/2)=1.96 TeV recorded by the CDF II experiment at the Tevatron. We find 268 (16) single (double) b-tagged candidate events, where 248 +/- 43 (14.4 +/- 2.7) are expected from standard model background processes. We place 95% confidence level upper limits on the Higgs boson production cross section for several Higgs boson masses ranging from 110 GeV/c2 to 140 GeV/c2. For a mass of 115 GeV/c2 the observed (expected) limit is 20.4 (14.2) times the standard model prediction.Comment: 8 pages, 2 figures, submitted to Phys. Rev. Let