19 research outputs found

    New Control Method For Fixed Speed Compressors With Side Stream

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    Case StudyProblem statement: Operability issues were experienced on flash gas back-to-back compressors with lower molecular weight side stream, driven by fixed speed electric motor: • Failed attempts of start-up/loading • During normal operation compressors went off-line due to process upset (e.g. inlet flow decrease) • Unable to operate parallel trains simultaneously. Consequent loss of production

    Efficacy of epidermal growth factor receptor targeting in advanced chordoma: case report and literature review

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    <p>Abstract</p> <p>Background</p> <p>Chordomas are very rare low-grade malignant bone tumors that arise from the embryonic rests of the notochord. They are characterized by slow growth and long history with frequent local relapses, and sometimes metastases. While chemotherapy is not efficient, imatinib has shown antitumor activity.</p> <p>Case presentation</p> <p>We report on a 76-year-old patient with EGFR-overexpressing advanced chordoma that progressed on imatinib and subsequently responded to erlotinib during 12 months.</p> <p>Conclusions</p> <p>We report the fourth case of advanced chordoma treated with an EGFR inhibitor. We also review the literature concerning the rationale and potential of EGFR targeting in chordoma.</p

    Post-starburst galaxies: more than just an interesting curiosity

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    From the VIMOS VLT DEEP Survey (VVDS) we select a sample of 16 galaxies with spectra which identify them as having recently undergone a strong starburst and subsequent fast quenching of star formation. These post-starburst galaxies lie in the redshift range 0.510^9.75Msun. They have a number density of 1x10^-4 per Mpc^3, almost two orders of magnitude sparser than the full galaxy population with the same mass limit. We compare with simulations to show that the galaxies are consistent with being the descendants of gas rich major mergers. Starburst mass fractions must be larger than ~5-10% and decay times shorter than ~10^8 years for post-starburst spectral signatures to be observed in the simulations. We find that the presence of black hole feedback does not greatly affect the evolution of the simulated merger remnants through the post-starburst phase. The multiwavelength spectral energy distributions of the post-starburst galaxies show that 5/16 have completely ceased the formation of new stars. These 5 galaxies correspond to a mass flux entering the red-sequence of rhodot(A->Q, PSB) = 0.0038Msun/Mpc^3/yr, assuming the defining spectroscopic features are detectable for 0.35Gyr. If the galaxies subsequently remain on the red sequence, this accounts for 38(+4/-11)% of the growth rate of the red sequence. Finally, we compare our high redshift results with a sample of galaxies with 0.05<z<0.1 observed in the SDSS and UKIDSS surveys. We find a very strong redshift evolution: the mass density of strong post-starburst galaxies is 230 times lower at z~0.07 than at z~0.7.Comment: 18 pages, 12 figures, to match version accepted to MNRAS. Minor reordering of text in places and Sec 2.2 on SPH simulation comparisons expande

    The MAORY first-light adaptive optics module for E-ELT

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    The MAORY adaptive optics module is part of the first light instrumentation suite for the E-ELT. The MAORY project phase B is going to start soon. This paper contains a system-level overview of the current instrument design

    Modelling human choices: MADeM and decision‑making

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    Research supported by FAPESP 2015/50122-0 and DFG-GRTK 1740/2. RP and AR are also part of the Research, Innovation and Dissemination Center for Neuromathematics FAPESP grant (2013/07699-0). RP is supported by a FAPESP scholarship (2013/25667-8). ACR is partially supported by a CNPq fellowship (grant 306251/2014-0)

    TT05 - Dry Gas Seal Failure Simulation Methodology

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    TutorialThe failure of dry gas seals is a critical event in Oil & Gas industry that if not correctly managed can lead to uncontrolled gas release to atmosphere. It is important to properly estimate the potential risks due to the failure and find appropriate solutions to mitigate them. The recent introduction of the API 692, covering the minimum requirements for dry gas sealing system, confirmed that this event can be taken as reference for a safer design of the seal gas system. The methodology developed to evaluate the system behavior in case of dry gas seal failure is described in the present paper. With such analysis it is possible to highlight critical points and evaluate mitigation measures, with the final scope of making sure that the sealing system design is robust and aligned to the most stringent API 692 requirements. A case study is also presented showing how the methodology was applied to revamp an old system design to comply with new End-User requirements based on API 692
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