Community-Level Responses to Iron Availability in Open Ocean Plankton Ecosystems

Predicting responses of plankton to variations in essential nutrients is hampered by limited in situ measurements, a poor understanding of community composition, and the lack of reference gene catalogs for key taxa. Iron is a key driver of plankton dynamics and, therefore, of global biogeochemical cycles and climate. To assess the impact of iron availability on plankton communities, we explored the comprehensive bio-oceanographic and bio-omics data sets from Tara Oceans in the context of the iron products from two state-of-the-art global scale biogeochemical models. We obtained novel information about adaptation and acclimation toward iron in a range of phytoplankton, including picocyanobacteria and diatoms, and identified whole subcommunities covarying with iron. Many of the observed global patterns were recapitulated in the Marquesas archipelago, where frequent plankton blooms are believed to be caused by natural iron fertilization, although they are not captured in large-scale biogeochemical models. This work provides a proof of concept that integrative analyses, spanning from genes to ecosystems and viruses to zooplankton, can disentangle the complexity of plankton communities and can lead to more accurate formulations of resource bioavailability in biogeochemical models, thus improving our understanding of plankton resilience in a changing environment

Acute Delta Hepatitis in Italy spanning three decades (1991–2019): Evidence for the effectiveness of the hepatitis B vaccination campaign

Updated incidence data of acute Delta virus hepatitis (HDV) are lacking worldwide. Our aim was to evaluate incidence of and risk factors for acute HDV in Italy after the introduction of the compulsory vaccination against hepatitis B virus (HBV) in 1991. Data were obtained from the National Surveillance System of acute viral hepatitis (SEIEVA). Independent predictors of HDV were assessed by logistic-regression analysis. The incidence of acute HDV per 1-million population declined from 3.2 cases in 1987 to 0.04 in 2019, parallel to that of acute HBV per 100,000 from 10.0 to 0.39 cases during the same period. The median age of cases increased from 27 years in the decade 1991-1999 to 44 years in the decade 2010-2019 (p < .001). Over the same period, the male/female ratio decreased from 3.8 to 2.1, the proportion of coinfections increased from 55% to 75% (p = .003) and that of HBsAg positive acute hepatitis tested for by IgM anti-HDV linearly decreased from 50.1% to 34.1% (p < .001). People born abroad accounted for 24.6% of cases in 2004-2010 and 32.1% in 2011-2019. In the period 2010-2019, risky sexual behaviour (O.R. 4.2; 95%CI: 1.4-12.8) was the sole independent predictor of acute HDV; conversely intravenous drug use was no longer associated (O.R. 1.25; 95%CI: 0.15-10.22) with this. In conclusion, HBV vaccination was an effective measure to control acute HDV. Intravenous drug use is no longer an efficient mode of HDV spread. Testing for IgM-anti HDV is a grey area requiring alert. Acute HDV in foreigners should be monitored in the years to come

Italian guidelines for primary headaches: 2012 revised version

The first edition of the Italian diagnostic and therapeutic guidelines for primary headaches in adults was published in J Headache Pain 2(Suppl. 1):105–190 (2001). Ten years later, the guideline committee of the Italian Society for the Study of Headaches (SISC) decided it was time to update therapeutic guidelines. A literature search was carried out on Medline database, and all articles on primary headache treatments in English, German, French and Italian published from February 2001 to December 2011 were taken into account. Only randomized controlled trials (RCT) and meta-analyses were analysed for each drug. If RCT were lacking, open studies and case series were also examined. According to the previous edition, four levels of recommendation were defined on the basis of levels of evidence, scientific strength of evidence and clinical effectiveness. Recommendations for symptomatic and prophylactic treatment of migraine and cluster headache were therefore revised with respect to previous 2001 guidelines and a section was dedicated to non-pharmacological treatment. This article reports a summary of the revised version published in extenso in an Italian version

The galaxy stellar mass function at 3.5 ≤z ≤ 7.5 in the CANDELS/UDS, GOODS-South, and HUDF fields

Context. The form and evolution of the galaxy stellar mass function (GSMF) at high redshifts provide crucial information on star formation history and mass assembly in the young Universe, close or even prior to the epoch of reionization. Aims: We used the unique combination of deep optical/near-infrared/mid-infrared imaging provided by HST, Spitzer, and the VLT in the CANDELS-UDS, GOODS-South, and HUDF fields to determine the GSMF over the redshift range 3.5 ≤ z ≤ 7.5. Methods: We used the HST WFC3/IR near-infrared imaging from CANDELS and HUDF09, reaching H ≃ 27 - 28.5 over a total area of 369 arcmin2, in combination with associated deep HST ACS optical data, deep Spitzer IRAC imaging from the SEDS programme, and deep Y and K-band VLT Hawk-I images from the HUGS programme, to select a galaxy sample with high-quality photometric redshifts. These have been calibrated with more than 150 spectroscopic redshifts in the range 3.5 ≤ z ≤ 7.5, resulting in an overall precision of σz/ (1 + z) ~ 0.037. With this database we have determined the low-mass end of the high-redshift GSMF with unprecedented precision, reaching down to masses as low as M∗ ~ 109 M☉ at z = 4 and ~6 × 109 M☉ at z = 7. Results: We find that the GSMF at 3.5 ≤ z ≤ 7.5 depends only slightly on the recipes adopted to measure the stellar masses, namely the photometric redshifts, the star formation histories, the nebular contribution, or the presence of AGN in the parent sample. The low-mass end of the GSMF is steeper than has been found at lower redshifts, but appears to be unchanged over the redshift range probed here. Meanwhile the high-mass end of the GSMF appears to evolve primarily in density, although there is also some evidence of evolution in characteristic mass. Our results are very different from previous mass function estimates based on converting UV galaxy luminosity functions into mass functions via tight mass-to-light relations. Integrating our evolving GSMF over mass, we find that the growth of stellar mass density is barely consistent with the time-integral of the star formation rate density over cosmic time at z> 4. Conclusions: These results confirm the unique synergy of the CANDELS+HUDF, HUGS, and SEDS surveys for the discovery and study of moderate/low-mass galaxies at high redshifts, and reaffirm the importance of space-based infrared selection for the unbiased measurement of the evolving GSMF in the young Universe. Appendices are available in electronic form at http://www.aanda.org <P /

A conceptual framework for understanding responsible leadership and presenteeism: the mediating influence of organizational commitment and employee turnover intentions

Presenteeism refers to reduced productivity caused by employees\u27 ill health. Presenteeism has a substantial impact on productivity and imposes a significant economic burden to businesses and national economies. In 2010, presenteeism costed the Australian economy $AUD 34.1 and the United States economy$USD180 billion. The purpose of this paper is to develop a conceptual framework supporting the relationship between perceived responsible leadership and presenteeism, and the mediating role of organizational commitment and employee turnover intentions. Implications of this conceptual framework are discussed both in terms of future research directions and intervention strategies

Transformational leadership, workplace engagement and the mediating influence of meaningful work: Building a conceptual framework

The purpose of this paper is to examine the nature of the relationship betweentransformational leadership, meaningful work and workplace engagement. Although there isconsensus that better engaged employees help organizations to perform better, industry reportsindicate that only one fifth of employees are engaged in their work. While there is some evidence inthe literature to suggest a link between transformational leadership factors such as idealizedinfluence, inspirational motivation, intellectual stimulation and individualized consideration, and thecomponents of workplace engagement such as vigor, dedication and absorption, little is known aboutthe nature of this relationship. This paper proposes a conceptual framework supporting an indirectrelationship between transformational leadership and followers workplace engagement, arelationship mediated by followers perceptions of meaningful work. The paper provides insights into enhancing followers workplace engagement via transformational leaders through their ability tocreate meaningful work. The proposed conceptual framework has implications for researchersexamining the link between transformational leadership and work engagement, and for organizationskeen to improve employee engagement levels through by leaders