Indirect Potable Reuse: A Sustainable Water Supply Alternative

The growing scarcity of potable water supplies is among the most important issues facing many cities, in particular those using single sources of water that are climate dependent. Consequently, urban centers are looking to alternative sources of water supply that can supplement variable rainfall and meet the demands of population growth. A diversified portfolio of water sources is required to ensure public health, as well as social, economical and environmental sustainability. One of the options considered is the augmentation of drinking water supplies with advanced treated recycled water. This paper aims to provide a state of the art review of water recycling for drinking purposes with emphasis on membrane treatment processes. An overview of significant indirect potable reuse projects is presented followed by a description of the epidemiological and toxicological studies evaluating any potential human health impacts. Finally, a summary of key operational measures to protect human health and the areas that require further research are discussed

Expanded access study of patients with advanced basal cell carcinoma treated with the Hedgehog pathway inhibitor, vismodegib

Background: Vismodegib, a first-in-class Hedgehog pathway inhibitor, was US Food and Drug Administration (FDA) approved for advanced basal cell carcinomas (BCCs) based on a single, nonrandomized, phase-II trial. Consequently, additional clinical data are critical to confirm the efficacy and safety of vismodegib

New Safety UTC Envisions Safe Systems Approach for U.S. Roadways

The Collaborative Sciences Center for Road Safety (CSCRS), the new University Transportation Center (UTC) at The University of North Carolina, Chapel Hill (UNC) is taking a fresh approach to road safety. This national safety UTC is focused on implementing a collaborative, multidisciplinary, safe systems approach to reducing transportation-related injuries and fatalities and to helping traffic safety become recognized as a public health priority in the United States

Effects of correctional boot camps on offending

Background: Correctional boot camps were first opened in United States adult correctional systems in 1983. Since that time they have rapidly grown, first within adult systems and later in juvenile corrections, primarily within the United States. In the typical boot camp, participants are required to follow a rigorous daily schedule of activities including drill and ceremony and physical training, similar to that of a military boot-camp. Punishment for misbehavior is immediate and swift and usually involves some type of physical activity like push-ups. Boot-camps differ substantially in the amount of focus given to the physical training and hard labor aspects of the program versus therapeutic programming such as academic education, drug treatment or cognitive skills. Objectives: To synthesize the extant empirical evidence on the effects of boot-camps and boot camp like programs on the criminal behavior (e.g., postrelease arrest, conviction, or reinstitutionalization) of convicted adult and juvenile offenders. Search Strategy: Numerous electronic databases were searched for both published an unpublished studies. The keywords used were: boot camp(s), intensive incarceration, and shock incarceration. We also contacted U.S and non-U.S. researchers working in this area requesting assistance in locating additional studies. The final search of these sources was completed in early December of 2003. Selection Criteria: The eligibility criteria were (a) that the study evaluated a correctional boot camp, shock incarceration, or intensive incarceration program; (b) that the study included a comparison group that received either probation or incarceration in an alternative facility; (c) that the study participants were exclusively under the supervision of the criminal or juvenile justice system; and (d) that the study reported a post-program measure of criminal behavior, such as arrest or conviction. Data Collection and Analysis: The coding protocol captured aspects of the research design, including methodological quality, the boot-camp program, the comparison group condition, the participant offenders, the outcome measures and the direction and magnitude of the observed effects. All studies were coded by two independent coders and all coding differences were resolved by Drs. MacKenzie or Wilson. Outcome effects were coded using the odds-ratio and meta-analysis was performed using the random effects model. Main Results: Thirty-two unique research studies met our inclusion criteria. These studies reported the results from 43 independent boot-camp/comparison samples. The random effects mean odds-ratio for any form of recidivism was 1.02, indicating that the likelihood that boot camp participants recidivating was roughly equal to the likelihood of comparison participants recidivating. This overall finding was robust to the selection of the outcome measure and length of follow-up. Methodological features were only weakly related to outcome among these studies and did not explain the null findings. The overall effect for juvenile boot camps was slightly lower than for adult boot camps. Moderator analysis showed that studies evaluating boot-camp programs with a strong treatment focus had a larger mean odds-ratio than studies evaluating boot camps with a weak treatment focus. Conclusions: Although the overall effect appears to be that of “no difference,” some studies found that boot camp participants did better than the comparison, while others found that comparison samples did better. However, all of these studies had the common element of a militaristic boot camp program for offenders. The current evidence suggests that this common and defining feature of a boot-camp is not effective in reducing post boot-camp offending

Wastewater irrigation: the state of play

As demand for fresh water intensifies, wastewater is frequently being seen as a valuable resource. Furthermore, wise reuse of wastewater alleviates concerns attendant with its discharge to the environment. Globally, around 20 million ha of land are irrigated with wastewater, and this is likely to increase markedly during the next few decades as water stress intensifies. In 1995, around 2.3 billion people lived in water-stressed river basins and this could increase to 3.5 billion by 2025. We review the current status of wastewater irrigation by providing an overview of the extent of the practice throughout the world and through synthesizing the current understanding of factors influencing sustainable wastewater irrigation. A theme that emerges is that wastewater irrigation is not only more common in water-stressed regions such as the Near East, but the rationale for the practice also tends to differ between the developing and developed worlds. In developing nations, the prime drivers are livelihood dependence and food security, whereas environmental agendas appear to hold greater sway in the developed world. The following were identified as areas requiring greater understanding for the long-term sustainability of wastewater irrigation: (i) accumulation of bioavailable forms of heavy metals in soils, (ii) environmental fate of organics in wastewater-irrigated soils, (iii) influence of reuse schemes on catchment hydrology, including transport of salt loads, (iv) risk models for helminth infections (pertinent to developing nations), (v) microbiological contamination risks for aquifers and surface waters, (vi) transfer efficiencies of chemical contaminants from soil to plants, (vii) health effects of chronic exposure to chemical contaminants, and (viii) strategies for engaging the public.<br /

Comment letters to the National Commission on Commission on Fraudulent Financial Reporting, 1987 (Treadway Commission) Vol. 2

https://egrove.olemiss.edu/aicpa_sop/1662/thumbnail.jp

The effects of custodial vs. non-custodial sentences on re-offending: A systematic review of the state of knowledge

As part of a broad initiative of systematic reviews of experimental or quasiexperimental evaluations of interventions in the field of crime prevention and the treatment of offenders, our work consisted in searching through all available databases for evidence concerning the effects of custodial and non-custodial sanctions on reoffending. For this purpose, we examined more than 3,000 abstracts, and finally 23 studies that met the minimal conditions of the Campbell Review, with only 5 studies based on a controlled or a natural experimental design. These studies allowed, all in all, 27 comparisons. Relatively few studies compare recidivism rates for offenders sentenced to jail or prison with those of offenders given some alternative to incarceration (typically probation). According to the findings, the rate of re-offending after a non-custodial sanction is lower than after a custodial sanction in 11 out of 13 significant comparisons. However, in 14 out of 27 comparisons, no significant difference on re-offending between both sanctions is noted. Two out of 27 comparisons are in favour of custodial sanctions. Finally, experimental evaluations and natural experiments yield results that are less favourable to non-custodial sanctions, than are quasi-experimental studies using softer designs. This is confirmed by the meta-analysis including four controlled and one natural experiment. According to the results, non-custodial sanctions are not beneficial in terms of lower rates of re-offending beyond random effects. Contradictory results reported in the literature are likely due to insufficient control of pre-intervention differences between prisoners and those serving “alternative” sanctions