197 research outputs found
Mixed symmetry superconductivity in two-dimensional Fermi liquids
We consider a 2D isotropic Fermi liquid with attraction in both and
channels and examine the possibility of a superconducting state with mixed
and symmetry of the gap function. We show that both in the weak coupling
limit and at strong coupling, a mixed symmetry state is realized in a
certain range of interaction. Phase transitions between the mixed and the pure
symmetry states are second order. We also show that there is no stable mixed
symmetry state at any coupling.Comment: 3 figures attached in uuencoded gzipped file
Charmless Exclusive Baryonic B Decays
We present a systematical study of two-body and three-body charmless baryonic
B decays. Branching ratios for two-body modes are in general very small,
typically less than , except that \B(B^-\to p \bar\Delta^{--})\sim
1\times 10^{-6}. In general, due to
the large coupling constant for . For three-body modes we
focus on octet baryon final states. The leading three-dominated modes are with a branching ratio of
order for and
for . The penguin-dominated decays with strangeness
in the meson, e.g., and , have appreciable rates and the mass
spectrum peaks at low mass. The penguin-dominated modes containing a strange
baryon, e.g., , have
branching ratios of order . In contrast, the decay
rate of is smaller. We explain why some of
charmless three-body final states in which baryon-antibaryon pair production is
accompanied by a meson have a larger rate than their two-body counterparts:
either the pole diagrams for the former have an anti-triplet bottom baryon
intermediate state, which has a large coupling to the meson and the
nucleon, or they are dominated by the factorizable external -emission
process.Comment: 46 pages and 3 figures, to appear in Phys. Rev. D. Major changes are:
(i) Calculations of two-body baryonic B decays involving a Delta resonance
are modified, and (ii) Penguin-dominated modes B-> Sigma+N(bar)+p are
discusse
A Measurement of the Decay Asymmetry Parameters in \Xi_{c}^{0}\to \X^{-}\pi^{+}
Using the CLEO II detector at the Cornell Electron Storage Ring we have
measured the decay asymmetry parameter in the decay . We find , using the world average value of
we obtain . The physically allowed range of a decay
asymmetry parameter is . Our result prefers a negative value:
is at the 90% CL. The central value occupies the
middle of the theoretically expected range but is not yet precise enough to
choose between models.Comment: 10 pages postscript, also available through
http://w4.lns.cornell.edu/public/CLN
Nonleptonic decays to , and other final states in Factorization
We consider nonleptonic Cabibbo--allowed decays in the
factorization approximation. We calculate nonleptonic decays of the type and relative to
and where we include among the
pseudoscalar states(P) and the vector states(V) the newly discovered
resonances, and . In the ratio of decays to
and relative to the decays to these states,
the poorly known decay constants of and cancel leading
to predictions that can shed light on the nature of these new states. In
general, we predict the decays to be larger than the corresponding
decays and in particular we find the branching ratio for can be between four to five times the branching ratio
for . This enhancement of branching
ratios follows primarily from the fact that more partial waves contribute in
decays than in decays. Our predictions are largely
independent of model calculations of hadronic inputs like form factors and
decay constants.Comment: 16 pages LaTe
Designing a broad-spectrum integrative approach for cancer prevention and treatment
Targeted therapies and the consequent adoption of "personalized" oncology have achieved notablesuccesses in some cancers; however, significant problems remain with this approach. Many targetedtherapies are highly toxic, costs are extremely high, and most patients experience relapse after a fewdisease-free months. Relapses arise from genetic heterogeneity in tumors, which harbor therapy-resistantimmortalized cells that have adopted alternate and compensatory pathways (i.e., pathways that are notreliant upon the same mechanisms as those which have been targeted). To address these limitations, aninternational task force of 180 scientists was assembled to explore the concept of a low-toxicity "broad-spectrum" therapeutic approach that could simultaneously target many key pathways and mechanisms. Using cancer hallmark phenotypes and the tumor microenvironment to account for the various aspectsof relevant cancer biology, interdisciplinary teams reviewed each hallmark area and nominated a widerange of high-priority targets (74 in total) that could be modified to improve patient outcomes. For thesetargets, corresponding low-toxicity therapeutic approaches were then suggested, many of which werephytochemicals. Proposed actions on each target and all of the approaches were further reviewed forknown effects on other hallmark areas and the tumor microenvironment. Potential contrary or procar-cinogenic effects were found for 3.9% of the relationships between targets and hallmarks, and mixedevidence of complementary and contrary relationships was found for 7.1%. Approximately 67% of therelationships revealed potentially complementary effects, and the remainder had no known relationship. Among the approaches, 1.1% had contrary, 2.8% had mixed and 62.1% had complementary relationships. These results suggest that a broad-spectrum approach should be feasible from a safety standpoint. Thisnovel approach has potential to be relatively inexpensive, it should help us address stages and types ofcancer that lack conventional treatment, and it may reduce relapse risks. A proposed agenda for futureresearch is offered
Hot deformation behavior and processing maps of diamond/Cu composites
The hot deformation behaviors of 50 vol pct uncoated and Cr-coated diamond/Cu composites were investigated using hot isothermal compression tests under the temperature and strain rate ranging from 1073 K to 1273 K (800 C to 1000 C) and from 0.001 to 5 s1, respectively. Dynamic recrystallization was determined to be the primary restoration mechanism during deformation. The Cr3C2 coating enhanced the interfacial bonding and resulted in a larger flow stress for the Cr-coated diamond/Cu composites. Moreover, the enhanced interfacial affinity led to a higher activation energy for the Cr-coated diamond/Cu composites (238 kJ/mol) than for their uncoated counterparts (205 kJ/mol). The strain-rate-dependent constitutive equations of the diamond/Cu composites were derived based on the Arrhenius model, and a high correlation (R = 0.99) was observed between the calculated flow stresses and experimental data. With the help of processing maps, hot extrusions were realized at 1123 K/0.01 s1 and 1153 K/0.01 s1 (850 C/0.01 s1 and 880 C/0.01 s1) for the uncoated and coated diamond/Cu composites, respectively. The combination of interface optimization and hot extrusion led to increases of the density and thermal conductivity, thereby providing a promising route for the fabrication of diamond/Cu composites
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease 2019 (COVID-19) pneumonia had neutralizing immunoglobulin G (IgG) autoantibodies (auto-Abs) against interferon-w (IFN-w) (13 patients), against the 13 types of IFN-a (36), or against both (52) at the onset of critical disease; a few also had auto-Abs against the other three type I IFNs. The auto-Abs neutralize the ability of the corresponding type I IFNs to block SARS-CoV-2 infection in vitro. These auto-Abs were not found in 663 individuals with asymptomatic or mild SARS-CoV-2 infection and were present in only 4 of 1227 healthy individuals. Patients with auto-Abs were aged 25 to 87 years and 95 of the 101 were men. A B cell autoimmune phenocopy of inborn errors of type I IFN immunity accounts for life-threatening COVID-19 pneumonia in at least 2.6% of women and 12.5% of men
Search for jet extinction in the inclusive jet-pT spectrum from proton-proton collisions at s=8 TeV
Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published articles title, journal citation, and DOI.The first search at the LHC for the extinction of QCD jet production is presented, using data collected with the CMS detector corresponding to an integrated luminosity of 10.7ââfbâ1 of proton-proton collisions at a center-of-mass energy of 8 TeV. The extinction model studied in this analysis is motivated by the search for signatures of strong gravity at the TeV scale (terascale gravity) and assumes the existence of string couplings in the strong-coupling limit. In this limit, the string model predicts the suppression of all high-transverse-momentum standard model processes, including jet production, beyond a certain energy scale. To test this prediction, the measured transverse-momentum spectrum is compared to the theoretical prediction of the standard model. No significant deficit of events is found at high transverse momentum. A 95% confidence level lower limit of 3.3 TeV is set on the extinction mass scale
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