Effect Of Salivary Contamination At Different Steps Of The Bonding Process On The Microleakage Around Class V Restorations

This study aimed to investigate the influence of the moment of salivary contamination during the bonding procedure (before or after acid conditioning) on the microleakage around composite resin restorations. Sixty bovine incisors received two Class V preparations (one with dentin margins and other with enamel margins). Teeth were randomly assigned into three, groups (n-20): 1) control (not contaminated); 2) salivary contamination before etching with 34% phosphoric acid; and, 3) salivary contamination after acid etching. Cavities were restored using Prime & Bond NT (Dentsply) adhesive system and TPH Spectrum (Dentsply) composite according to manufacturer instructions. Teeth were thermocycled (500x, 5-55°C, 60s/bath), immersed in 2% methylenee blue buffered solution (pH 7.0), and sectioned into two halves. Three examiners measured the extent of dye penetration or dentin and enamel margins in a stereoscope microscope, using four representative scores. Statistical analysis were performed with Kruskal-Wallis/Wilcoxon tests (α-5%). The results showed that enamel and dentin margins did not present significant differences (p>0.05). However, significantly higher dye penetration was observed on substrates etched and further contaminated with saliva. It was concluded that salivary contamination after acid etching increases the microleakage around composite resin restorations, especially at dentin margins. However, acid etching subsequent to the contamination can avoid negative effects on restorations margins.62314451449Van Meerbeek, B., Van Landuyt, K., De Munck, J., Hashimoto, M., Peumans, M., Lambrechts, P., Technique -sensitivity of contemporary adhesives (2005) Dent Mater J, 24, pp. 1-13Civelek, A., Ersoy, M., L'Hotelier, E., Soyman, M., Say, E.C., Polymerization shrinkage and microleakage in Class II cavities of various resin composites (2003) Oper Dent, 28, pp. 635-641Besnault, C., Attal, J.P., Influence of a simulated oral environment on microleakage of two adhesive systems in Class II composite restorations (2002) J Dent, 30, pp. 1-6Spencer, P., Wang, Y., Bohaty, B., Interfacial chemistry of moisture-aged class II composite restorations (2006) J Biomed Mater Res B Appl Biomater, 77, pp. 234-240Direct and indirect restorative materials (2003) J Am Dent Assoc, 134, pp. 463-472. , Council on Scientific Affairs ADASoldani, F., Foley, J., An assessment of rubber dam usage amongst specialists in paediatric dentistry practising within the UK (2007) Int J Paediatr Dent, 17, pp. 50-56Fernandes, A.S., Rodrigues, S., Singhal, K., Murthi, M.S., Assessment of chair side techniques for composite resin restoration - a survey (2003) Indian J Dent Res, 14, pp. 47-56Taskonak, B., Sertgoz, A., Shear bond strengths of saliva contaminated 'one-bottle' adhesives (2002) J Oral Rehabil, 29, pp. 559-564Eiriksson, S.O., Pereira, P.N., Swift Jr., E.J., Heymann, H.O., Sigurdsson, A., Effects of saliva contamination on resin-resin bond strength (2004) Dent Mater, 20, pp. 37-44Hiraishi, N., Kitasako, Y., Nikaido, T., Nomura, S., Burrow, M.F., Tagami, J., Effect of artificial saliva contamination on pH value change and dentin bond strength (2003) Dent Mater, 19, pp. 429-434Park, J.W., Lee, K.C., The influence of salivary contamination on shear bond strength of dentin adhesive systems (2004) Oper Dent, 29, pp. 437-442Yoo, H.M., Oh, T.S., Pereira, P.N., Effect of saliva contamination on the microshear bond strength of one-step self-etching adhesive systems to dentin (2006) Oper Dent, 31, pp. 127-134Hitmi, L., Attal, J.P., Degrange, M., Influence of the time-point of salivary contamination on dentin shear bond strength of 3 dentin adhesive systems (1999) J Adhes Dent, 1, pp. 219-232Reis, A.F., Giannini, M., Kavaguchi, A., Soares, C.J., Line, S.R., Comparison of microtensile bond strength to enamel and dentin of human, bovine, and porcine teeth (2004) J Adhes Dent, 6, pp. 117-121Eiriksson, S.O., Pereira, P.N., Swift, E.J., Heymann, H.O., Sigurdsson, A., Effects of blood contamination on resin-resin bond strength (2004) Dent Mater, 20, pp. 184-190Toledano, M., Osorio, R., Ceballos, L., Fuentes, M.V., Fernandes, C.A., Tay, F.R., Microtensile bond strength of several adhesive systems to different dentin depths (2003) Am J Dent, 16, pp. 292-29

Reproducibility in the absence of selective reporting : An illustration from large-scale brain asymmetry research

Altres ajuts: Max Planck Society (Germany).The problem of poor reproducibility of scientific findings has received much attention over recent years, in a variety of fields including psychology and neuroscience. The problem has been partly attributed to publication bias and unwanted practices such as p-hacking. Low statistical power in individual studies is also understood to be an important factor. In a recent multisite collaborative study, we mapped brain anatomical left-right asymmetries for regional measures of surface area and cortical thickness, in 99 MRI datasets from around the world, for a total of over 17,000 participants. In the present study, we revisited these hemispheric effects from the perspective of reproducibility. Within each dataset, we considered that an effect had been reproduced when it matched the meta-analytic effect from the 98 other datasets, in terms of effect direction and significance threshold. In this sense, the results within each dataset were viewed as coming from separate studies in an "ideal publishing environment," that is, free from selective reporting and p hacking. We found an average reproducibility rate of 63.2% (SD = 22.9%, min = 22.2%, max = 97.0%). As expected, reproducibility was higher for larger effects and in larger datasets. Reproducibility was not obviously related to the age of participants, scanner field strength, FreeSurfer software version, cortical regional measurement reliability, or regional size. These findings constitute an empirical illustration of reproducibility in the absence of publication bias or p hacking, when assessing realistic biological effects in heterogeneous neuroscience data, and given typically-used sample sizes

Search for jet extinction in the inclusive jet-pT spectrum from proton-proton collisions at s=8 TeV

Published by the American Physical Society under the terms of the Creative Commons Attribution 3.0 License. Further distribution of this work must maintain attribution to the author(s) and the published articles title, journal citation, and DOI.The first search at the LHC for the extinction of QCD jet production is presented, using data collected with the CMS detector corresponding to an integrated luminosity of 10.7  fb−1 of proton-proton collisions at a center-of-mass energy of 8 TeV. The extinction model studied in this analysis is motivated by the search for signatures of strong gravity at the TeV scale (terascale gravity) and assumes the existence of string couplings in the strong-coupling limit. In this limit, the string model predicts the suppression of all high-transverse-momentum standard model processes, including jet production, beyond a certain energy scale. To test this prediction, the measured transverse-momentum spectrum is compared to the theoretical prediction of the standard model. No significant deficit of events is found at high transverse momentum. A 95% confidence level lower limit of 3.3 TeV is set on the extinction mass scale

Search for the associated production of the Higgs boson with a top-quark pair

A search for the standard model Higgs boson produced in association with a top-quark pair t t ¯ H (tt¯H) is presented, using data samples corresponding to integrated luminosities of up to 5.1 fb −1 and 19.7 fb −1 collected in pp collisions at center-of-mass energies of 7 TeV and 8 TeV respectively. The search is based on the following signatures of the Higgs boson decay: H → hadrons, H → photons, and H → leptons. The results are characterized by an observed t t ¯ H tt¯H signal strength relative to the standard model cross section, μ = σ/σ SM ,under the assumption that the Higgs boson decays as expected in the standard model. The best fit value is μ = 2.8 ± 1.0 for a Higgs boson mass of 125.6 GeV

Measurement of the inclusive 3-jet production differential cross section in proton-proton collisions at 7 TeV and determination of the strong coupling constant in the TeV range

This paper presents a measurement of the inclusive 3-jet production differential cross section at a proton–proton centre-of-mass energy of 7 TeV using data corresponding to an integrated luminosity of 5 fb-1 collected with the CMS detector. The analysis is based on the three jets with the highest transverse momenta. The cross section is measured as a function of the invariant mass of the three jets in a range of 445–3270 GeV and in two bins of the maximum rapidity of the jets up to a value of 2. A comparison between the measurement and the prediction from perturbative QCD at next-to-leading order is performed. Within uncertainties, data and theory are in agreement. The sensitivity of the observable to the strong coupling constant αS is studied. A fit to all data points with 3-jet masses larger than 664 GeV gives a value of the strong coupling constant of αS(MZ)=0.1171±0.0013(exp)-0.0047+0.0073(theo)

Measurement of the differential cross section for top quark pair production in pp collisions at √s=8 TeV

The normalized differential cross section for top quark pair (tt¯) production is measured in pp collisions at a centre-of-mass energy of 8TeV at the CERN LHC using the CMS detector in data corresponding to an integrated luminosity of 19.7fb-1. The measurements are performed in the lepton+jets (e/μ++jets) and in the dilepton e+e-, μ+μ-, and e±μ∓) decay channels. The tt¯ cross section is measured as a function of the kinematic properties of the charged leptons, the jets associated to b quarks, the top quarks, and the tt¯ system. The data are compared with several predictions from perturbative quantum chromodynamic up to approximate next-to-next-to-leading-order precision. No significant deviations are observed relative to the standard model predictions. © 2015, CERN for the benefit of the CMS collaboration

Measurement of prompt Jψ\psi pair production in pp collisions at \sqrt s = 7 Tev

Production of prompt J/ ψ meson pairs in proton-proton collisions at s s√ = 7 TeV is measured with the CMS experiment at the LHC in a data sample corresponding to an integrated luminosity of about 4.7 fb −1 . The two J/ ψ mesons are fully reconstructed via their decays into μ + μ − pairs. This observation provides for the first time access to the high-transverse-momentum region of J/ ψ pair production where model predictions are not yet established. The total and differential cross sections are measured in a phase space defined by the individual J/ ψ transverse momentum ( p T J/ ψ ) and rapidity (| y J/ ψ |): | y J/ ψ | 6.5 GeV/ c ; 1.2 4.5 GeV/ c . The total cross section, assuming unpolarized prompt J/ ψ pair production is 1.49 ± 0.07 (stat) ±0.13 (syst) nb. Different assumptions about the J/ ψ polarization imply modifications to the cross section ranging from −31% to +27%