Towards bamboo agroforestry development in Ghana: evaluation of crop performance, soil properties and economic benefit

In the quest to promote bamboo agroforestry in the dry semi-deciduous forest zone of Ghana, we evaluated changes in soil properties, crop productivity and the economic potential of a bamboobased intercropping system. The intercropping system was established from 3-months old sympodial bamboo (Bambusa balcooa) seedlings planted at a 5 m95 m spacing and intercropped with maize, cassava or cowpea. Separate monocropping fields for maize, cassava, cowpea and bamboo were set up adjacent to the intercropped field. In both the intercropping and monocropping fields, plots were with fertilizer treatments and without. The experiment was laid out in a split plot design with four replicates and studied over three years. Economic analysis was conducted using the financial benefit-cost ratio method. The results showed that regardless of fertilizer treatments, bamboo agroforestry and monocropped fields had comparable effects on soil properties and crop productivity within two years of establishment. In the third year, however, bamboo agroforestry had significantly (p\0.05) higher soil moisture, pH and crop productivity levels. An intercropping advantage over monocropping was evident for all crops with respective partial land equivalent ratios for fertilized and non-fertilized intercropped systems as follows: cowpea (1.37 and 1.54), maize (1.38 and 1.36), and cassava (1.12 and 1.19). The economic evaluation also indicated marginal profitability of bamboo intercropping over monocropping systems. From the results obtained, there are clear indications that where bamboo is a prioritized woody perennial, integrated systems with crops may be encouraged

Socioeconomic Indicators of Bamboo Use for Agroforestry Development in the Dry Semi-Deciduous Forest Zone of Ghana

Bamboo agroforestry is currently being promoted in Ghana as a viable land use option to reduce dependence on natural forest for wood fuels. To align the design and introduction of bamboo agroforestry to the needs of farmers, information on the determinants of bamboo acceptability and adoption is necessary. It is, therefore, the aim of this study to determine how socioeconomic factors, local farming practices and local knowledge on bamboo may influence its acceptability and adoption as a component of local farming systems. Data were collected from 200 farmers in the dry semi-deciduous forest zone of Ghana using semi-structured questionnaire interviews. The results show that farmers’ traditional knowledge on bamboo including its use for charcoal production and leaves for fodder are influential determinants of bamboo adoption. Among the demographic characteristics of farmers, age and gender are the most significant predictors. It is also evident that the regular practice of leaving trees on farmlands and type of cropping system may influence bamboo integration into traditional farming systems

One third of alloantibodies in patients with sickle cell disease transfused with African blood are missed by the standard red blood cell test panel

Studies on red blood cell (RBC) antibodies in Africa routinely use standard test cells from donors of Caucasian descent. There are no systematic data on alloimmunization against antigens that are almost exclusively present in Africans. We studied the prevalence of antibodies in transfused Ghanaian patients with sickle cell disease (SCD) using standard test cells (representing predominantly antigens more common in Caucasians (Caucasian antigens) and cells expressing antigens more common among Africans (African antigens). Antibodies were present in 16% of 221 patients; 31% of these were directed against African antigens that were not detected with standard test cells. Our findings are not only relevant for an African setting, but also for Western blood banks that are developing strategies to recruit more African donors

Auswirkungen von Biokohle, Abwasserbewässerung und Düngung auf Bodeneigenschaften unter urbaner Landwirtschaft in Westafrika

Die zunehmende nachfrageorientierte Intensivierung der Agrarproduktion im semiariden Westafrika wird aus bodenkundlicher Sicht durch geringe Bodenfruchtbarkeit und hohen Bodendegradationsraten limitiert. Als vielversprechende Möglichkeit zur Bodenverbesserung wird seit einiger Zeit Biokohle vorgeschlagen. Zudem wird im städtischen Umfeld ungeklärtes Abwasser zur Bewässerung eingesetzt. Denn Abwasser wird nicht nur als ganzjährige Wasserquelle, sondern auch als Nährstoffquelle für Böden und Pflanzen betrachtet, trotz des hohen Kontaminationsrisikos durch Pathogene und Schwermetalle. Wissenslücken bestehen vor allem bezüglich der Wechselwirkungen zwischen Biokohle, Düngung und Abwasserbewässerung und Bodeneigenschaften. Das Ziel dieser Studie war daher die Untersuchung der Auswirkungen von Biokohle (hergestellt aus Ernterückständen des Mais- und Reisanbaus), organischer und anorganischer Düngung, Bewässerungsqualität und Bewässerungsquantität auf die Bodeneigenschaften von zwei sandigen, humus- und nährstoffarmen Böden unter Gemüseanbau im urbanen Raum von Tamale (Nordghana) und Ouagadougou (Burkina Faso) über einen Zeitraum von zwei Jahren. Die Applikation von Biokohle bewirkte eine Verdoppelung der C-Vorräte auf beiden Standorten, allerdings wurden anschließend C-Verluste in Höhe von 35 % in Ouagadougou und 46 % in Tamale beobachtet. Korrigiert durch die Auswirkungen der Landnutzungsänderungen verringern sich die C-Verluste in Tamale auf ebenfalls 35 %. Beide Biokohlen hatten keine Auswirkungen auf den pH-Wert, die KAK und das verfügbare P. Die Applikation von Reishülsenbiokohle führte zur N-Retention (18 % höhere N-Vorräte im Vergleich zur Kontrolle), wohingegen die Maisspindelkohle keine Auswirkung auf den N-Haushalt hatte. In Tamale führte die NPK Düngung zur Erhöhung des verfügbaren P sowie zur Versauerung (0.65 pH-Einheiten) und zur Verringerung der effektiven Basensättigung (von nahezu 100% auf 93%) aufgrund der geringen Pufferkapazität des Bodens. In Ouagadougou führte die regelmäßige organische Düngung mit Rindermist zur Erhöhung der C- und N-Vorräte und der KAK. Die einzigen Auswirkungen der Abwasserbewässerung waren ein Anstieg des austauschbaren Natriums und des pH Wertes. Die Ergebnisse der Untersuchungen an beiden Standorten zeigen, dass die Auswirkungen von Biokohle, die aus Ernterückständen hergestellt wurde, und Abwasserbewässerung auf die Bodeneigenschaften geringer sind als in früheren Studien beschrieben wurde

School Banking as a Strategy for Strengthening Youth Economic Participation in Developing Countries: Lessons from YouthSave

Schools are the primary settings where both education and health services are delivered to youth in developing countries. A similar approach can be used for financial inclusion. Financial inclusion, in turn, can lead to positive youth development outcomes in education and health. But a critical first step is financial access. This study examines how schools can serve as the setting for financial education and financial services, increasing youth economic participation. Research in four developing countries finds an increase in youth savings account uptake when financial institutions provide opportunities at schools for youth to receive financial education, open savings accounts, and make deposits. Findings are that school banking can overcome some of the regulatory, geographic, and information barriers that limit youth access to safe and affordable savings services. Marginalized youth, including those who are low-income and females, participate as much as other youth. We conclude that schools can play an important role in increasing youth economic participation, a positive step toward economic strengthening and overall well-being. As a possible implication, school-based health programming might consider integrating school banking features, such as opening savings accounts, into future program design and implementation

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London

Exploring the relationship between chronic undernutrition and asymptomatic malaria in Ghanaian children

<p>Abstract</p> <p>Background</p> <p>A moderate association has been found between asymptomatic parasitaemia and undernutrition. However, additional investigation using the gold standard for asymptomatic parasitaemia confirmation, polymerase chain reaction (PCR), is needed to validate this association. Anthropometric measurements and blood samples from children less than five years of age in a rural Ghanaian community were used to determine if an association exists between chronic undernutrition and PCR-confirmed cases of asymptomatic malaria.</p> <p>Methods</p> <p>This was a descriptive cross-sectional study of 214 children less than five years of age from a community near Kumasi, Ghana. Blood samples and anthropometric measurements from these children were collected during physical examinations conducted in January 2007 by partners of the Barekuma Collaborative Community Development Programme.</p> <p>Results</p> <p>Findings from the logistic model predicting the odds of asymptomatic malaria indicate that children who experienced mild, moderate or severe stunting were not more likely to have asymptomatic malaria than children who were not stunted. Children experiencing anaemia had an increased likelihood (OR = 4.15; 95% CI: 1.92, 8.98) of asymptomatic malaria. Similarly, increased spleen size, which was measured by ultrasound, was also associated with asymptomatic malaria (OR = 2.17; 95% CI: 1.44, 3.28). Fast breathing, sex of the child, and age of the child were not significantly associated with the asymptomatic malaria.</p> <p>Conclusions</p> <p>No significant association between chronic undernutrition and presence of asymptomatic malaria was found. Children who experience anaemia and children who have splenomegaly are more likely to present asymptomatic malaria. Programmes aimed at addressing malaria should continue to include nutritional components, especially components that address anaemia.</p

T Cell Responses to the RTS,S/AS01E and RTS,S/AS02D Malaria Candidate Vaccines Administered According to Different Schedules to Ghanaian Children

BACKGROUND: The Plasmodium falciparum pre-erythrocytic stage candidate vaccine RTS,S is being developed for protection of young children against malaria in sub-Saharan Africa. RTS,S formulated with the liposome based adjuvant AS01(E) or the oil-in-water based adjuvant AS02(D) induces P. falciparum circumsporozoite (CSP) antigen-specific antibody and T cell responses which have been associated with protection in the experimental malaria challenge model in adults. METHODS: This study was designed to evaluate the safety and immunogenicity induced over a 19 month period by three vaccination schedules (0,1-, 0,1,2- and 0,1,7-month) of RTS,S/AS01(E) and RTS,S/AS02(D) in children aged 5-17 months in two research centers in Ghana. Control Rabies vaccine using the 0,1,2-month schedule was used in one of two study sites. RESULTS: Whole blood antigen stimulation followed by intra-cellular cytokine staining showed RTS,S/AS01(E) induced CSP specific CD4 T cells producing IL-2, TNF-α, and IFN-γ. Higher T cell responses were induced by a 0,1,7-month immunization schedule as compared with a 0,1- or 0,1,2-month schedule. RTS,S/AS01(E) induced higher CD4 T cell responses as compared to RTS,S/AS02(D) when given on a 0,1,7-month schedule. CONCLUSIONS: These findings support further Phase III evaluation of RTS,S/AS01(E). The role of immune effectors and immunization schedules on vaccine protection are currently under evaluation. TRIAL REGISTRATION: ClinicalTrials.gov NCT00360230