The Hope of the World: The Story of Jesus and its Influence in the Formation of Identity in Working Class Girls in Britain 1900-1945

The aim of this thesis is to investigate how the British Sunday school story of Jesus functioned in the formation of identity of working class girls 1900-1945. In doing so, the thesis argues that the British Sunday school network during this period provided an effective institutional base for the promotion of a popular version of developmental theory known as child study, the influence of which fed into the establishment of the pedagogies of storytelling and the educational use of pictures. It explains how the Sunday school story of Jesus was one of the most accessible narratives available to working class children, but argues that this was a reframed version of the story which was formulated to take into account insights into child psychology gained through developmental theory and which acknowledged the varying needs of different age groups. The title of the thesis, The Hope of the World, is taken from a Sunday school picture of Jesus and is used here because it is seen as emblematic of the Edwardian view of children as the potential redeemers of the nation. The thesis analyses the books, pictures and ephemera telling the story of Jesus which were produced for circulation in the Sunday school and argues that, through accident rather than design, these narratives invariably made a greater appeal to girls than boys. It shows that despite the reframing of the Jesus story as a fairy tale, adventure story and chivalric romance there were always problems encountered in producing an image of Jesus which would make a lasting, positive impression on boys. The thesis concludes by arguing that for working class girls in particular, the chivalric romance provided them with the means of identifying with Jesus, their knightly Saviour, through which they could negotiate their negative feelings about their own subordinate socia-economic positioning and that this was an effective means of inculcating the notion of altruistic citizenship

UC-249 Hemorrhage

Hemorrhage is a fast-paced FPS action game with a focus on risky gameplay and dodging enemy attacks. Fight your way through hordes of grotesque creatures and make it to the end! The player starts with limited health but can steal more from killing enemies. Then, you can unleash this stored-up health to deal massive damage to your foes! Will you choose to be an unkillable tank? Or a brutal glass cannon

Effect of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker initiation on organ support-free days in patients hospitalized with COVID-19

IMPORTANCE Overactivation of the renin-angiotensin system (RAS) may contribute to poor clinical outcomes in patients with COVID-19. Objective To determine whether angiotensin-converting enzyme (ACE) inhibitor or angiotensin receptor blocker (ARB) initiation improves outcomes in patients hospitalized for COVID-19. DESIGN, SETTING, AND PARTICIPANTS In an ongoing, adaptive platform randomized clinical trial, 721 critically ill and 58 non–critically ill hospitalized adults were randomized to receive an RAS inhibitor or control between March 16, 2021, and February 25, 2022, at 69 sites in 7 countries (final follow-up on June 1, 2022). INTERVENTIONS Patients were randomized to receive open-label initiation of an ACE inhibitor (n = 257), ARB (n = 248), ARB in combination with DMX-200 (a chemokine receptor-2 inhibitor; n = 10), or no RAS inhibitor (control; n = 264) for up to 10 days. MAIN OUTCOMES AND MEASURES The primary outcome was organ support–free days, a composite of hospital survival and days alive without cardiovascular or respiratory organ support through 21 days. The primary analysis was a bayesian cumulative logistic model. Odds ratios (ORs) greater than 1 represent improved outcomes. RESULTS On February 25, 2022, enrollment was discontinued due to safety concerns. Among 679 critically ill patients with available primary outcome data, the median age was 56 years and 239 participants (35.2%) were women. Median (IQR) organ support–free days among critically ill patients was 10 (–1 to 16) in the ACE inhibitor group (n = 231), 8 (–1 to 17) in the ARB group (n = 217), and 12 (0 to 17) in the control group (n = 231) (median adjusted odds ratios of 0.77 [95% bayesian credible interval, 0.58-1.06] for improvement for ACE inhibitor and 0.76 [95% credible interval, 0.56-1.05] for ARB compared with control). The posterior probabilities that ACE inhibitors and ARBs worsened organ support–free days compared with control were 94.9% and 95.4%, respectively. Hospital survival occurred in 166 of 231 critically ill participants (71.9%) in the ACE inhibitor group, 152 of 217 (70.0%) in the ARB group, and 182 of 231 (78.8%) in the control group (posterior probabilities that ACE inhibitor and ARB worsened hospital survival compared with control were 95.3% and 98.1%, respectively). CONCLUSIONS AND RELEVANCE In this trial, among critically ill adults with COVID-19, initiation of an ACE inhibitor or ARB did not improve, and likely worsened, clinical outcomes. TRIAL REGISTRATION ClinicalTrials.gov Identifier: NCT0273570

Big Talk, 6/26/2014

Al Brewer interviews author Sandy Martin about his new book, Paddling Against the Tide: The Story of Lincoln Canoe, an Entrepreneurial Saga.https://digitalcommons.usm.maine.edu/wmpg_bigtalk/1118/thumbnail.jp

Parties and Elections in America: The Electoral Process

This classic text provides an in-depth examination and history of American political parties and their critical role in representative democracy at the local, state, and national levels. Focused on the continued evolution and significance of parties in the American political system, separate chapters are devoted to key topics such as the impact of social media in the electoral process, and recent developments in campaign finance. The seventh edition fully incorporates the results of the 2012 presidential election and the 2014 midterm elections, as well as the impact of the Tea Party within the Republican party and important demographic shifts in the American electorate.https://digitalcommons.library.umaine.edu/fac_monographs/1269/thumbnail.jp

Not so bad: avoidance and aversive discounting modulate threat appraisal in anterior cingulate and medial prefrontal cortex

The dorsal anterior cingulate (adACC) and dorsal medial prefrontal cortex (dmPFC) play a central role in the discrimination and appraisal of threatening stimuli. Yet, little is known about what specific features of threatening situations recruit these regions and how avoidance may modulate appraisal and activation through prevention of aversive events. In this investigation, thirty healthy adults underwent functional neuroimaging while completing an avoidance task in which responses to an Avoidable CS+ threat prevented delivery of an aversive stimulus, but not to an Unavoidable CS+ threat. Extinction testing was also completed where CSs were presented without aversive stimulus delivery and an opportunity to avoid. The Avoidable CS+ relative to the Unavoidable CS+ was associated with reductions in ratings of negative valence, fear, and US expectancy and activation. Greater regional activation was consistently observed to the Unavoidable CS+ during avoidance, which declined during extinction. Individuals exhibiting greater aversive discounting---more avoidant of immediate monetary loss compared to a larger delayed loss---also displayed greater activation to the Unavoidable CS+, highlighting aversive discounting as a significant individual difference variable. These are the first results linking adACC/dmPFC reactivity to avoidance-based reductions of aversive events and modulation of activation by individual differences in aversive discounting