Solar flares and their associated processes

The evolution of the solar neutrino flux which is described by the wave function $\Psi^T=(\nu_{eL},\nu_{XL}, \overline{\nu}_{eL}, \overline{\nu}_{XL})$ is examined. Our treatment of the problem holds for any standard model (SM) extensions possessing nonzero dipole magnetic and anapole moments. When the solar neutrino flux moves through the solar flare (SF) region in the preflare period, then it undergoes the additional (compared with the SM) resonance conversions. As a result, the weakening the electron neutrinos flux takes place. On the other hand, existence of the additional resonances lead to appearance of the $\overline{\nu}_{eL}$ and $\overline{\nu}_{XL}$ neutrinos that could be detected by the terrestrial detectors. The hypothesis of the $\nu_e$-induced $\beta$-decays is also discussed. According to it, before the large SF, decreasing the $\beta$-decay rate for some elements takes place. The possible influence of the electron antineutrino flux produced in the superflares on the regime of the hypothetical georeactor is considered.Comment: 11 pages. arXiv admin note: text overlap with arXiv:hep-ph/0401221 by other author

Molecular characterization, tissue expression and sequence variability of the barramundi (Lates calcarifer) myostatin gene

Background: Myostatin (MSTN) is a member of the transforming growth factor-β superfamily that negatively regulates growth of skeletal muscle tissue. The gene encoding for the MSTN peptide is a consolidate candidate for the enhancement of productivity in terrestrial livestock. This gene potentially represents an important target for growth improvement of cultured finfish.\ud \ud Results: Here we report molecular characterization, tissue expression and sequence variability of the barramundi (Lates calcarifer) MSTN-1 gene. The barramundi MSTN-1 was encoded by three exons 379, 371 and 381 bp in length and translated into a 376-amino acid peptide. Intron 1 and 2 were 412 and 819 bp in length and presented typical GT...AG splicing sites. The upstream region contained cis-regulatory elements such as TATA-box and E-boxes. A first assessment of sequence variability suggested that higher mutation rates are found in the 5' flanking region with several SNP's present in this species. A putative micro RNA target site has also been observed in the 3'UTR (untranslated region) and is highly conserved across teleost fish. The deduced amino acid sequence was conserved across vertebrates and exhibited characteristic conserved putative functional residues including a cleavage motif of proteolysis (RXXR), nine cysteines and two glycosilation sites. A qualitative analysis of the barramundi MSTN-1 expression pattern revealed that, in adult fish, transcripts are differentially expressed in various tissues other than skeletal muscles including gill, heart, kidney, intestine, liver, spleen, eye, gonad and brain.\ud \ud Conclusion: Our findings provide valuable insights such as sequence variation and genomic information which will aid the further investigation of the barramundi MSTN-1 gene in association with growth. The finding for the first time in finfish MSTN of a miRNA target site in the 3'UTR provides an opportunity for the identification of regulatory mutations on the expression of this gene

The 2005 Nevada Rangeland Vegetation Survey General Public Questionnaire and Survey of Responses

The 2005 Nevada Rangeland Vegetation Survey was conducted as a collaborative effort between the University of Nevada, Reno (UNR) Department of Resource Economics and the University of Nevada Cooperative Extension (UNCE) Natural Resources Program to fulfill two roles

A Methodology for Risk Assessment to Improve the Resilience and Sustainability of Critical Infrastructure with Case Studies from the United States Army

Reliable performance of energy and water infrastructure is central to the mission readiness of the United States Army. These systems are vulnerable to coordinated attacks from an adversary as well as disruption from natural events. The objectives of this work were to investigate Army installations in North America, identify best practices for improving the resilience and sustainability of critical energy and water infrastructure, and develop a framework and methodology for analyzing the resilience of an installation under varying outage scenarios. This work was accomplished using a multi-layered decision process to identify unique case studies from the 117 active-duty domestic Army installations. A framework for analyzing and assessing the resilience of an installation was then developed to help inform stakeholders. Metered energy and water data from buildings across Fort Benning, GA were curated to inform the modeling framework, including a discrete-event simulation of the supply and demand for energy and water on the installation using ProModel. This simulation was used to study the scale of solutions required to address outage events of varying frequency, duration, and magnitude, the combination of which is described as the severity of outages at a given site. This project helps develop a framework to inform how installations might meet Army Directive 2020-03, which states that installations must be able to sustain mission requirements for a minimum of 14 days after a disruption has occurred

Outcome of carotid stent-assisted angioplasty versus open surgical repair of recurrent carotid stenosis

AbstractPurposeWe compared outcome and durability of carotid stent-assisted angioplasty (CAS) with open surgical repair (ie, repeat carotid endarterectomy [CEA]) to treat recurrent carotid stenosis (RCS).MethodsA retrospective review of anatomic and neurologic outcomes was carried out after 27 repeat CEA procedures (1993-2002) and 52 CAS procedures (1997-2002) performed to treat high-grade internal carotid artery (ICA) RCS after CEA. The incidence of intervention because of symptomatic RCS was similar (repeat CEA, 63%; CAS, 60%), but the interval from primary CEA to repeat intervention was greater (P < .05) in the repeat CEA group (83 ± 15 months) compared with the CAS group (50 ± 8 months). In the CAS group, 17 of 52 arteries (33%) were judged not to be surgical candidates because of surgically inaccessible high lesions (n = 8), medical comorbid conditions (n = 4), neck irradiation (n = 3), or previous surgery with cranial nerve deficit or stroke (n = 2). Three patients who underwent repeat CEA had lesions not appropriate for treatment with CAS.ResultsOverall 30-day morbidity was similar after CAS (12%; death due to ipsilateral intracranial hemorrhage, 1; nondisabling stroke, 1; reversible neurologic deficits or transient ischemic attack, 2; access site complication, 2) and repeat CEA (11%; no death; nondisabling stroke, 1; reversible cranial nerve injury, 1; cervical hematoma, 1). Combined stroke and death rate was 3.7% for repeat CEA and 5.7% for CAS (P > .1). All duplex ultrasound scans obtained within 3 months after CEA and CAS demonstrated patent ICA and velocity spectra of less than 50% stenosis. During follow-up, no repeat CEA (mean, 39 months) or CAS (mean, 26 months) repair demonstrated ICA occlusion, but two patients (8%) who underwent repeat CEA and 4 patients (8%) who underwent CAS required balloon or stent angioplasty because of 80% RCS. At last follow-up, no patient had ipsilateral stroke and all ICA remain patent. At duplex scanning, stenosis-free (<50% diameter reduction) ICA patency at 36 months was 75% after repeat CEA and 57% after CAS (P = .26, log-rank test).ConclusionsCarotid angioplasty for treatment of high-grade stenotic ICA after CEA resulted in similar anatomic and neurologic outcomes compared with open surgical repair. Most lesions are amenable to endovascular therapy, and CAS enabled treatment in patients judged not to be suitable surgical candidates. Duplex scanning surveillance after repeat CEA or CAS is recommended, because stenosis can recur after either secondary procedure

Early Infrared Spectral Development of V1187 Scorpii (Nova Scorpii 2004 No. 2)

We report on an unprecedented infrared time series of spectra of V1187 Sco, a very fast ONeMg nova. The observations covered a 56 day period (2004 August 6-September 30) starting 2 days after the nova's peak brightness. Time evolution of the spectra revealed changing line strengths and profiles on timescales of less than a day to weeks as the nova evolved from early postmaximum to early coronal phases. When our ground-based optical and Spitzer Space Telescope data were combined, the wavelength coverage of 0.38-36 μm allowed an accurate spectral energy distribution to be derived when it was about 6 weeks after outburst. Developing double structure in the He I lines showed them changing from narrow to broad in only a few days. Using the O I lines in combination with the optical spectra, we derived a reddening of E(B - V) = 1.56 ± 0.08 and a distance of 4.9 ± 0.5 kpc. Modeling of the ejected material strongly suggested that it was geometrically thick with ΔR/R = 0.8-0.9 (more of a wind than a shell) and a low filling factor of order a few percent. The line shapes were consistent with a cylindrical jet, bipolar, or spherical Hubble flow expansion with a maximum speed of about -3000 km s-1. The central peak appeared to be more associated with the spherical component, while the two peaks (especially in Hβ) suggested a ring with either a lower velocity component or with its axis inclined to the line of sight

The state of the Martian climate

60°N was +2.0°C, relative to the 1981–2010 average value (Fig. 5.1). This marks a new high for the record. The average annual surface air temperature (SAT) anomaly for 2016 for land stations north of starting in 1900, and is a significant increase over the previous highest value of +1.2°C, which was observed in 2007, 2011, and 2015. Average global annual temperatures also showed record values in 2015 and 2016. Currently, the Arctic is warming at more than twice the rate of lower latitudes

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis

: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) encodes several proteins that inhibit host interferon responses. Among these, ORF6 antagonizes interferon signaling by disrupting nucleocytoplasmic trafficking through interactions with the nuclear pore complex components Nup98-Rae1. However, the roles and contributions of ORF6 during physiological infection remain unexplored. We assessed the role of ORF6 during infection using recombinant viruses carrying a deletion or loss-of-function (LoF) mutation in ORF6. ORF6 plays key roles in interferon antagonism and viral pathogenesis by interfering with nuclear import and specifically the translocation of IRF and STAT transcription factors. Additionally, ORF6 inhibits cellular mRNA export, resulting in the remodeling of the host cell proteome, and regulates viral protein expression. Interestingly, the ORF6:D61L mutation that emerged in the Omicron BA.2 and BA.4 variants exhibits reduced interactions with Nup98-Rae1 and consequently impairs immune evasion. Our findings highlight the role of ORF6 in antagonizing innate immunity and emphasize the importance of studying the immune evasion strategies of SARS-CoV-2

The VMC ESO Public Survey

The VISTA near-infrared YJKs survey of the Magellanic Clouds system (VMC) has entered its core phase: about 50% of the observations across the Large and Small Magellanic Clouds (LMC, SMC), the Magellanic Bridge and Stream have already been secured and the data are processed and analysed regularly. The initial analyses, concentrated on the first two completed tiles in the LMC (including 30 Doradus and the South Ecliptic Pole), show the superior quality of the data. The photometric depth of the VMC survey allows the derivation of the star formation history (SFH) with unprecedented quality compared to previous wide-area surveys, while reddening maps of high angular resolution are constructed using red clump stars. The multi-epoch Ks-band data reveal tight period-luminosity relations for variable stars and permit the measurement of accurate proper motions of the stellar populations. The VMC survey continues to acquire data that will address many issues in the field of star and galaxy evolution