188 research outputs found

    Caracterización de la gingivitis crónica en la población adolescente

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    Introduction: chronic gingivitis is the inflammatory process that affects the periodontium of protection and alters the normal characteristics of the gingiva, with a high prevalence in adolescents.Objective: to characterize chronic gingivitis in adolescents from 11 to 19 years old in the North Area of Sancti Spiritus province.Methods: an observational, descriptive and cross-sectional study was carried out; the target group comprised 61 adolescents, who attended the Provincial Teaching Dentistry Clinic during the period of September 2019-January 2020. The variables studied were: age, sex, factors of risk, clinical anatomy characteristic, severity of the disease and knowledge about chronic gingivitis. Methods from the theoretical and empirical levels, along with descriptive statistics were used.Results: the age group 17-19 years (45,9 %) predominated, poor oral hygiene (78,7 %) followed by dental caries (47,5 %) and smoking (40,9 %). The level of knowledge was poor in 72,1 % and edematous gingivitis was the one that most affected adolescents, with the highest incidence in the ages from 14 to 16 (36,1%).Conclusions: chronic gingivitis, mainly of the edematous type, was common in male adolescents in ages from 17 to 19. Risk factors such as poor oral hygiene influenced on the onset of this disease. It is necessary to increase the level of knowledge on adolescents to prevent the onset of this condition.Introducción: la gingivitis crónica es el proceso inflamatorio que afecta el periodonto de protección y altera las características normales de la encía, con elevada prevalencia en los adolescentes.Objetivo: caracterizar la gingivitis crónica en los adolescentes de 11 a 19 años del Área Norte de Sancti Spíritus.Métodos: se realizó un estudio observacional, descriptivo y transversal cuyo universo quedó constituido por 61 adolescentes, que acudieron a la Clínica Estomatológica Docente Provincial durante el período de septiembre de 2019 a enero de 2020. Las variables estudiadas fueron: edad, sexo, factores de riesgo, aspecto anatomo clínico, gravedad de la enfermedad y conocimientos sobre gingivitis crónica. Se emplearon métodos del nivel teórico, empírico y de la estadística descriptiva.Resultados: predominó el grupo de edades de 17 a 19 años (45,9 %), la higiene bucal deficiente (78,7 %) seguida de la caries dental (47,5 %) y el tabaquismo (40,9 %). El nivel de conocimientos fue malo en el 72,1 % y la gingivitis edematosa fue la que más afectó a los adolescentes, con mayor incidencia en el grupo de 14 a 16 años (36,1 %).Conclusiones: la gingivitis crónica, principalmente de tipo edematosa fue común en adolescentes masculinos y de edades entre 17 y 19 años. Factores de riesgo como una higiene bucal deficiente condicionan la aparición de la enfermedad. Es necesario incidir en el nivel de conocimientos de los adolescentes para prevenir la aparición de la enfermedad

    Periodontal diseases in the child and adolescent

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    Background: Periodontal diseases are among the most frequent diseases affecting children and adolescents. These include gingivitis, localized or generalized aggressive periodontitis (a.k.a., early onset periodontitis which includes generalized or localized prepubertal periodontitis and juvenile periodontitis) and periodontal diseases associated with systemic disorders. The best approach to managing periodontal diseases is prevention, followed by early detection and treatment. Methods: This paper reviews the current literature concerning the most common periodontal diseases affecting children: chronic gingivitis (or dental plaque-induced gingival diseases) and early onset periodontitis (or aggressive periodontitis), including prepubertal and juvenile periodontitis. In addition, systemic diseases that affect the periodontium and oral lesions commonly found in young children are addressed. The prevalence, diagnostic characteristics, microbiology, host-related factors, and therapeutic management of each of these disease entities are thoroughly discussed.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73561/1/j.1600-051X.2002.290504.x.pd

    Exploring the oral microbiota of children at various developmental stages of their dentition in the relation to their oral health

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    <p>Abstract</p> <p>Background</p> <p>An understanding of the relation of commensal microbiota to health is essential in preventing disease. Here we studied the oral microbial composition of children (N = 74, aged 3 - 18 years) in natural transition from their deciduous to a permanent dentition and related the microbial profiles to their oral health status. The microbial composition of saliva was assessed by barcoded pyrosequencing of the V5-V6 hypervariable regions of the 16 S rRNA, as well as by using phylogenetic microarrays.</p> <p>Results</p> <p>Pyrosequencing reads (126174 reads, 1045 unique sequences) represented 8 phyla and 113 higher taxa in saliva samples. Four phyla - Firmicutes, Bacteriodetes, Proteobacteria and Actinobacteria - predominated in all groups. The deciduous dentition harboured a higher proportion of Proteobacteria (Gammaproteobacteria, Moraxellaceae) than Bacteroidetes, while in all other groups Bacteroidetes were at least as abundant as Proteobacteria. Bacteroidetes (mainly genus <it>Prevotella</it>), Veillonellaceae family, Spirochaetes and candidate division TM7 increased with increasing age, reflecting maturation of the microbiome driven by biological changes with age.</p> <p>Microarray analysis enabled further analysis of the individual salivary microbiota. Of 350 microarray probes, 156 gave a positive signal with, on average, 77 (range 48-93) probes per individual sample.</p> <p>A caries-free oral status significantly associated with the higher signal of the probes targeting <it>Porphyromonas catoniae </it>and <it>Neisseria flavescens</it>.</p> <p>Conclusions</p> <p>The potential role of <it>P. catoniae </it>and <it>N. flavescens </it>as oral health markers should be assessed in large-scale clinical studies. The combination of both, open-ended and targeted molecular approaches provides us with information that will increase our understanding of the interplay between the human host and its microbiome.</p

    A Case of Unerupted Lower Primary Second Molar Associated with Compound Odontoma

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    Odontoma is the most common type of benign odontogenic tumor, and often causes disturbances in the eruption of its associated tooth. Odontomas usually occur in the permanent dentition, and rarely occur solely in the primary dentition. This case report documents a six-year-old-child with a compound odontoma located in the mandible, which caused the impaction of the primary second molar

    Management of Crown-related Fractures in Children: An Update Review

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    Traumatic dental injuries (TDIs) are a serious public health problem. Epidemiology of dental trauma indicates that these injuries are more prevalent in child population of the world. Children are the sufferers in two-thirds of all TDIs observed. Although being a major fraction, crown-related fractures are a less severe form of TDIs with respect to their complications and sequelae. However, as with other types of traumatic injuries, the delay in seeking for immediate care following a traumatic injury and the lack of appropriate treatment may compromise long-term outcomes. This article reviews the occurrence, management, and prognosis of crown-related fractures in primary and permanent teeth in light of the recent literature

    Therapeutic targeting of cathepsin C::from pathophysiology to treatment

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    Cathepsin C (CatC) is a highly conserved tetrameric lysosomal cysteine dipeptidyl aminopeptidase. The best characterized physiological function of CatC is the activation of pro-inflammatory granule-associated serine proteases. These proteases are synthesized as inactive zymogens containing an N-terminal pro-dipeptide, which maintains the zymogen in its inactive conformation and prevents premature activation, which is potentially toxic to the cell. The activation of serine protease zymogens occurs through cleavage of the N-terminal dipeptide by CatC during cell maturation in the bone marrow. In vivo data suggest that pharmacological inhibition of pro-inflammatory serine proteases would suppress or attenuate deleterious effects of inflammatory/auto-immune disorders mediated by these proteases. The pathological deficiency in CatC is associated with Papillon-Lefèvre syndrome. The patients however do not present marked immunodeficiency despite the absence of active serine proteases in immune defense cells. Hence, the transitory pharmacological blockade of CatC activity in the precursor cells of the bone marrow may represent an attractive therapeutic strategy to regulate activity of serine proteases in inflammatory and immunologic conditions. A variety of CatC inhibitors have been developed both by pharmaceutical companies and academic investigators, some of which are currently being employed and evaluated in preclinical/clinical trials

    Alveolar bone level at deciduous molars in Flemish children: A retrospective, radiographic study

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    peer reviewedAIM: The aim of this retrospective radiographic study in Flemish children was to examine the bone level and bone loss around deciduous molars and factors influencing this. MATERIALS AND METHODS: Two thousand eight hundred ninety six digital intra-oral radiographs of children younger than 18 years old were screened for eligibility. The distance from the cementoenamel junction to the alveolar bone crest was measured, and tooth surfaces were screened for local risk factors that are presumably related to changes in the bone level. A distance >2 mm was defined as bone loss based on previous literature. All measurements were performed by two examiners. RESULTS: One thousand four hundred ninety one radiographs of 796 patients (mean age 6.46 ± 2.38 years) were included. The distance between the cementoenamel junction and the alveolar bone crest ranged from 0.07 to 2.88 mm, and the mean distance was 0.93 ± 0.37 mm. This distance was positively correlated with age (p < .001). In 3.5% of patients, bone loss was diagnosed. Caries, fillings and pulp pathology were associated with bone loss and higher cementoenamel junction-alveolar bone crest distances (p < .05). CONCLUSION: This study found a low prevalence of alveolar bone loss in the primary dentition. Both the bone level and bone loss were strongly correlated with local factors
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