255 research outputs found
Mining team characteristics to predict Wikipedia article quality
International audienceIn this study, we were interested in studying which characteristics of virtual teams are good predictors for the quality of their production. The experiment involved obtaining the Spanish Wikipedia database dump and applying different data mining techniques suitable for large data sets to label the whole set of articles according to their quality (comparing them with the Featured/Good Articles, or FA/GA). Then we created the attributes that describe the characteristics of the team who produced the articles and using decision tree methods, we obtained the most relevant characteristics of the teams that produced FA/GA. The team's maximum efficiency and the total length of contribution are the most important predictors. This article contributes to the literature on virtual team organization
A clinal polymorphism in the insulin signaling transcription factor foxo contributes to life-history adaptation in Drosophila*
A fundamental aim of adaptation genomics is to identify polymorphisms that underpin variation in fitness traits. In Drosophila melanogaster, latitudinal lifeâhistory clines exist on multiple continents and make an excellent system for dissecting the genetics of adaptation. We have previously identified numerous clinal singleânucleotide polymorphism in insulin/insulinâlike growth factor signaling (IIS), a pathway known from mutant studies to affect life history. However, the effects of natural variants in this pathway remain poorly understood. Here we investigate how two clinal alternative alleles at foxo, a transcriptional effector of IIS, affect fitness components (viability, size, starvation resistance, fat content). We assessed this polymorphism from the North American cline by reconstituting outbred populations, fixed for either the lowâ or highâlatitude allele, from inbred DGRP lines. Because diet and temperature modulate IIS, we phenotyped alleles across two temperatures (18°C, 25°C) and two diets differing in sugar source and content. Consistent with clinal expectations, the highâ latitude allele conferred larger body size and reduced wing loading. Alleles also differed in starvation resistance and expression of insulinâlike receptor, a transcriptional target of FOXO. Allelic reaction norms were mostly parallel, with few GxE interactions. Together, our results suggest that variation in IIS makes a major contribution to clinal lifeâhistory adaptation
Multiyear Maize management dataset collected in Chiapas, Mexico
For several decades, maize (Zea mays L.) management decisions in smallholder farming in tropical regions have been a puzzle. To best balance alternative management practices' environmental and economic outcomes, an extensive dataset was gathered through CIMMYT's knowledge hub in Chiapas, a state in southern Mexico. In a knowledge hub, farmers, with the support of farm advisors, compare conventional and improved agronomic practices side-by-side and install demonstration fields where they implement improved practices. In all these fields data on on-farm operations and results is collected. The dataset was assembled using field variables (yield, cultivars, fertilization and tillage practice), as well as environment variables from soil mapping (slope, elevation, soil texture, pH and organic matter concentration) and gridded weather datasets (precipitation, temperature, radiation and evapotranspiration). The dataset contains observations from 4585 fields and comprises a period of 7 years between 2012 and 2018. This dataset will facilitate analytical approaches to represent spatial and temporal variability of alternative crop management decisions based on observational data and explain model-generated predictions for maize in Chiapas, Mexico. In addition, this data can serve as an example for similar efforts in Big Data in Agriculture
la imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia - municipio de Mosquera y la ciudad de BogotĂĄ
Los impactos que deja el conflicto armado en Colombia contienen huellas innumerables de los sĂmbolos que representa este flagelo junto con la violencia fĂsica, verbal y psicolĂłgica que supone un entorno en disputa. Esta temĂĄtica se aborda a travĂ©s de los siguientes apartados. Un anĂĄlisis de relatos e historias âCasode Shimaiaâ (ComisiĂłn de la verdad, 2022), quien es una vĂctima del desplazamiento armado por la disputa de tierras, mostrĂĄndonos el contexto de una realidad del pueblo BarĂ, contemplando las siguientes preguntas, ÂżquĂ© persona se vio mĂĄs afectada? ÂżQuĂ© factores de riesgo psicosocial influyeron en la comunidad Bari a causa del conflicto armado?, ÂżQuĂ© nuevos retos identifican en su comunidad luego de retornar a su territorio?â. En segunda instancia se presenta el anĂĄlisis del caso âLa masacre del Saladoâ identificando un hecho de violencia armada a cargo de las AUC, con mĂĄs de cien pĂ©rdidas humanas, ocasionando el abandono del pueblo por sus supervivientes, se proponen tres fases de acciĂłn para la dignificaciĂłn de sus vĂctimas: UnificaciĂłn, voz al dolor a travĂ©s del arte y crecimiento de la poblaciĂłn por conocimiento de sus fortalezas. Luego se comparte el informe analĂtico Foto-Voz, que busca conectar lo simbĂłlico de la imagen con la memoria y su importancia para rescatar la voz de las vĂctimas, concluyendo que, la violencia es un fenĂłmeno multifactorial que necesita del contexto particular para proponer salidas cada vez mĂĄs eficientes a su presencia y sus consecuencias en las vĂctimas contemplando conceptos como, memoria, fortalezas, emergentes psicosociales, ciencia, arte y educaciĂłnThe impacts of the armed conflict in Colombia leave countless traces of the symbols thatrepresent this scourge, along with the physical, verbal, and psychological violence that a disputed environment entails. This topic is addressed through the following sections. An analysis of stories and narratives "Shimaia Case," (truth commission, 2022), who is a victim of armed displacement due to land disputes, showing us the context of the reality of the Bari people, considering the following questions, who was most affected? What psychosocial risk factors influenced the Bari community due to the armed conflict? Whatnew challenges do they identify in their community after returning to their territory?
Secondly, the analysis of the "La masacre del Salado" case identifies an armed violence event by the AUC, with over one hundred human losses, causing the abandonment of thetown by its survivors. Three phases of action are proposed for the dignity of its victims: Unification, giving voice to the pain through art, and growth of the population through knowledge of their strengths. Then, the analytical report "Foto-Voz" is shared, which seeks to connect the symbolism of the image with memory and its importance in rescuingthe voice of the victims, concluding that violence is a multifactorial phenomenon that needs particular context to propose increasingly efficient solutions to its presence and its consequences on victims, contemplating concepts such as memory, strengths, psychosocial emergents, science, art, and education
New criteria for the equation of state development: Simple model fluids
Recently we have proposed (J. Chem. Phys. 128 (2008) 134508) a new rescaling
of fluid density by its critical value to apply the
corresponding states law for the attractive Yukawa fluids study. Analysis of
precise simulation results allows us to generalize this concept to the case of
simple fluids with different interparticle interactions, like Mie (n,m) and
Sutherland pair potentials. It is shown, that there is a linear relationship
between the critical pressure and critical temperature, as well as the critical
density and inverse critical temperature for these frequently used pair
potentials. As a consequence, the critical compressibility factor of these
model fluids is close to its universal value measured experimentally for
different real substances.Comment: 5 pages, 3 figure
Impact of COVID-19 pandemic on cardiometabolic patients without SARS CoV-2 infection in Latin America
A cross-sectional survey including 38 questions about demography, clinical condition, changes in health habits, and medical treatments for cardiometabolic patients in outpatient follow-up was conducted. From June 15 to July 15, 2020, a total of 13 Latin-American countries participated in enrolling patients. These countries were divided into 3 geographic regions: Region 1 including North, Central, and Caribbean Regions (NCCR), Region 2 including the Andean Region (AR), and Region 3 including the Southern Cone Region (SCR). 4.216 patients were analyzed, resulting in a coefficient of 33.82%, 32.23%, and 33.94% for NCCR, AR, and SCR, respectively. Significant differences were found between the AR, SCR, and NCCR regions. The analysis of habitual medication usage showed that discontinued use of medication was more present in AR, reaching almost 30% (p < 0.001). The main finding of this study was the negative impact that restrictive measures have on adherence to medications and physical activity: Rs = 0.84 (p = 0.0003) and Rs = 0.61 (p = 0.0032), respectively. AR was the most vulnerable region. Restrictive quarantine measures imposed by the different countries showed a positive correlation with medication discontinuation and a negative correlation with physical activity levels in patients analyzed. These findings characterize the impact of the consequences left by this pandemic. Undoubtedly, restrictive measures have been and will continue to have reverberating negative effects in most Latin-American countries.Fil: Camiletti, Jorge. Hospital Italiano de La Plata; ArgentinaFil: Renna, Nicolas Federico. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - Mendoza. Instituto de Medicina y BiologĂa Experimental de Cuyo; Argentina. Universidad Nacional de Cuyo. Facultad de Ciencias MĂ©dicas. CĂĄtedra de FisiologĂa PatolĂłgica; Argentina. Hospital Español de Mendoza; ArgentinaFil: LĂłpez Santi, Ricardo. Hospital Italiano de La Plata; ArgentinaFil: Erriest, Juan. Hospital Italiano de La Plata; ArgentinaFil: GarcĂa-Bello, Eliomar. Centro de DiagnĂłstico Medicina Avanzada
y Telemedicina; RepĂșblica DominicanaFil: Araujo, John. Centro Cardiovascular Somer Incare; ColombiaFil: Varleta-Olivares, Paola. Hospital Dipreca; ChileFil: GĂłmez-DĂaz, Eduardo. Hospital Metropolitano del Norte; VenezuelaFil: RamĂrez, Gisselle. Medicina Cardiovascular Asociada; RepĂșblica DominicanaFil: Berni Betancourt, Ana. Sociedad interamericana de CardiologĂa; MĂ©xico. Consejo Interamericano de ElectrocardiogrĂĄfica y Arritmias; MĂ©xico. Hospital Ăngeles Pedregal; MĂ©xicoFil: Escalada Lesme, Gustavo. Centro MĂ©dico Nacional-Hospital Nacional ItaguĂĄ; ParaguayFil: Campos AlcĂĄntara, Lourdes V.. Consultorio de Lourdes Victoria Campos AlcĂĄntara; PerĂșFil: Moya Loor, Leonardo. Hospital Santa Margarita; EcuadorFil: Rey Benavente, Claudio. Hospital Arroyabe Pichanal; ArgentinaFil: Almonte, Claudia. Medicina Cardiovascular Asociada; RepĂșblica DominicanaFil: Cortez Sandoval, Maicol. Hospital Nacional Edgardo Rebagliti Martins; PerĂșFil: Alvarado Cuadros, MarĂa. Department of Cardiology, Institution; EcuadorFil: Rosario, Monica I.. Centro de DiagnĂłstico Medicina Avanzada
y Telemedicina; RepĂșblica DominicanaFil: Gupta, Shyla. Queenâs University; CanadĂĄFil: Ibarrola, Martin. Cardiovascular Center BV; ArgentinaFil: Baranchuk, AdriĂĄn. Kingston Health Sciences Centre; Canad
The surprising negative correlation of gene length and optimal codon use - disentangling translational selection from GC-biased gene conversion in yeast
<p>Abstract</p> <p>Background</p> <p>Surprisingly, in several multi-cellular eukaryotes optimal codon use correlates negatively with gene length. This contrasts with the expectation under selection for translational accuracy. While suggested explanations focus on variation in strength and efficiency of translational selection, it has rarely been noticed that the negative correlation is reported only in organisms whose optimal codons are biased towards codons that end with G or C (-GC). This raises the question whether forces that affect base composition - such as GC-biased gene conversion - contribute to the negative correlation between optimal codon use and gene length.</p> <p>Results</p> <p>Yeast is a good organism to study this as equal numbers of optimal codons end in -GC and -AT and one may hence compare frequencies of optimal GC- with optimal AT-ending codons to disentangle the forces. Results of this study demonstrate in yeast frequencies of GC-ending (optimal AND non-optimal) codons decrease with gene length and increase with recombination. A decrease of GC-ending codons along genes contributes to the negative correlation with gene length. Correlations with recombination and gene expression differentiate between GC-ending and optimal codons, and also substitution patterns support effects of GC-biased gene conversion.</p> <p>Conclusion</p> <p>While the general effect of GC-biased gene conversion is well known, the negative correlation of optimal codon use with gene length has not been considered in this context before. Initiation of gene conversion events in promoter regions and the presence of a gene conversion gradient most likely explain the observed decrease of GC-ending codons with gene length and gene position.</p
Anatomy of the sign-problem in heavy-dense QCD
QCD at finite densities of heavy quarks is investigated
using the density-of-states method. The phase factor
expectation value of the quark determinant is calculated to
unprecedented precision as a function of the chemical potential.
Results are validated using those from a reweighting
approach where the latter can produce a significant signalto-noise
ratio. We confirm the particleâhole symmetry at low
temperatures, find a strong sign problem at intermediate values
of the chemical potential, and an inverse Silver Blaze
feature for chemical potentials close to the onset value: here,
the phase-quenched theory underestimates the density of the
full theory
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