121 research outputs found
Tailoring the frictional properties of granular media
A method of modifying the roughness of soda-lime glass spheres is presented,
with the purpose of tuning inter-particle friction. The effect of chemical
etching on the surface topography and the bulk frictional properties of grains
is systematically investigated. The surface roughness of the grains is measured
using white light interferometry and characterised by the lateral and vertical
roughness length scales. The underwater angle of repose is measured to
characterise the bulk frictional behaviour. We observe that the co-efficient of
friction depends on the vertical roughness length scale. We also demonstrate a
bulk surface roughness measurement using a carbonated soft drink.Comment: 10 pages, 17 figures, submitted to Phys. Rev.
Interindividual variabilities in cognitive performance degradation after alcohol consuption and sleep loss are related
Introduction
The sleep inducing effects of alcohol as well as the increase in sleep propensity and sleepiness after sleep loss have been linked to the adenosinergic system in the brain. While the performance impairing effects of ethanol have partly been related to the inhibitory effects of cerebral adenosine, sleep loss has been found to increase adenosine receptor density. The interindividual variability of cognitive performance impairments after alcohol intake as well as after sleep loss is extensive. Thus, we examined in humans whether performance degradations resulting from sleep loss and alcohol consumption are related.
Methods
Performance in a 10-min Psychomotor Vigilance Task (PVT) was tested in 47 healthy volunteers (mean age 27 ± 5 (SD) years, 21 females) at 6 pm 1) after an 8 hour control night, 2) after alcohol consumption (aiming at a blood alcohol concentration (BAC) of 0.08%), and 3) after 35 hours of total sleep deprivation. After alcohol intake, 35 of the participants reached a BAC of more than 0.06% prior to the performance testing (mean BAC 0.074%, SD 0.009%, min. 0.063%, max. 0.095%) and were included in the analyses. Two recovery nights were scheduled between conditions.
Results
Performance impairments due to acute alcohol intake and due to 35 hours of sustained wakefulness were calculated as differences from performance under control conditions. The degree in performance degradation correlated highly between both conditions (i.e. 10% slowest reaction times: Pearson’s r=0.73, p<0.0001; standard deviation of reaction times: r=0.75, p<0.0001; mean reaction time: r=0.59, p=0.0002).
Conclusions
Participants whose PVT performance proved to be vulnerable to the effects of alcohol consumption were also vulnerable to sleep loss, whereas individuals who were resilient against the effects of alcohol were also less susceptible to the impact of sleep deprivation. These results suggest that the effects of alcohol and sleep deprivation on performance are mediated – at least in part – by a common pathway that may involve the adenosinergic system in the brain
Eine Strategieanalyse der Diakonie Deutschland und des Paritätischen Gesamtverbands
Zugleich: Dissertation, Universität Kassel, 202
Sleep deprivation decreases eye gaze entropy in women but not in men in a manual spacecraft docking task: indications of an adaptation of scanning strategy
INTRODUCTION
Fatigue is a pressing problem in driving, aviation, and spaceflight and represents a root cause of
15-20% of accidents in transportation operations. Changes in visual scanning efficiency have been
associated with sleep deprivation. This study investigates the effect of 24h of sleep deprivation on
scanning efficiency and spatial distribution of fixations by means of gaze entropy in a spacecraft
docking task, during which participants had to manually control a simulated spacecraft with 6 DoF.
METHODS
A counterbalanced crossover design with a sleep deprivation condition and a control condition was
used. Linear mixed models were applied to analyze the data of 61 participants between the ages of
20 and 39 years (M = 24.90, SD = 4.68) with 28 female participants. Subjective sleepiness ratings
were collected before each test session, wherein the participants conducted a sustained attention
task as well as the 6df task. During the test session, eye-tracking data was continuously recorded.
RESULTS
An interaction between sleep deprivation and gender of the participants significantly affected both
entropy measures. Female participants showed a significant decrease in gaze transition entropy (p
< .01) and stationary gaze entropy (p < .05) during sleep deprivation compared to male participants.
This suggests a reduction of scanning complexity and a more exploitative examination of the visual
scene, respectively, in response to sleepiness. A significant association between gaze transition
entropy and docking performance depending on trial difficulty was found (p < .05). Lower scanning
complexity (GTE) was linked to better performance, but only in easier trials.
CONCLUSION
Sleep deprivation leads to alterations of gaze behavior in female participants, possibly as an
adaptive reaction during a critical operational task. Women reduce their visual scanning
complexity, a change that was associated with better performance in easy trials. Future research
needs to identify optimal entropy ranges for specific docking maneuvers to guide docking training
and inform strategies to mitigate the impact of fatigu
Effects of total sleep deprivation on performance in a manual spacecraft docking task
Sleep deprivation and circadian rhythm disruptions are highly prevalent in shift workers, and also among astronauts. Resulting sleepiness can reduce cognitive performance, lead to catastrophic occupational events, and jeopardize space missions. We investigated whether 24 hours of total sleep deprivation would affect performance not only in the Psychomotor Vigilance Task (PVT), but also in a complex operational task, i.e. simulated manual spacecraft docking. Sixty-two healthy participants completed the manual docking simulation 6df and the PVT once after a night of total sleep deprivation and once after eight hours of scheduled sleep in a counterbalanced order. We assessed the impact of sleep deprivation on docking as well as PVT performance and investigated if sustained attention is an essential component of operational performance after sleep loss. The results showed that docking accuracy decreased significantly after sleep deprivation in comparison to the control condition, but only at difficult task levels. PVT performance deteriorated under sleep deprivation. Participants with larger impairments in PVT response speed after sleep deprivation also showed larger impairments in docking accuracy. In conclusion, sleep deprivation led to impaired 6df performance, which was partly explained by impairments in sustained attention. Elevated motivation levels due to the novelty and attractiveness of the task may have helped participants to compensate for the effects of sleepiness at easier task levels. Continued testing of manual docking skills could be a useful tool both to detect sleep loss-related impairments and assess astronauts’ readiness for duty during long-duration missions
Mapping of QTL for Resistance against the Crucifer Specialist Herbivore Pieris brassicae in a New Arabidopsis Inbred Line Population, Da(1)-12×Ei-2
In Arabidopsis thaliana and other crucifers, the glucosinolate-myrosinase system contributes to resistance against herbivory by generalist insects. As yet, it is unclear how crucifers defend themselves against crucifer-specialist insect herbivores.We analyzed natural variation for resistance against two crucifer specialist lepidopteran herbivores, Pieris brassicae and Plutella xylostella, among Arabidopsis thaliana accessions and in a new Arabidopsis recombinant inbred line (RIL) population generated from the parental accessions Da(1)-12 and Ei-2. This RIL population consists of 201 individual F(8) lines genotyped with 84 PCR-based markers. We identified six QTL for resistance against Pieris herbivory, but found only one weak QTL for Plutella resistance. To elucidate potential factors causing these resistance QTL, we investigated leaf hair (trichome) density, glucosinolates and myrosinase activity, traits known to influence herbivory by generalist insects. We identified several previously unknown QTL for these traits, some of which display a complex pattern of epistatic interactions.Although some trichome, glucosinolate or myrosinase QTL co-localize with Pieris QTL, none of these traits explained the resistance QTL convincingly, indicating that resistance against specialist insect herbivores is influenced by other traits than resistance against generalists
Response of Sunflower (Helianthus annuus L.) Leaf Surface Defenses to Exogenous Methyl Jasmonate
Helianthus annuus, the common sunflower, produces a complex array of secondary compounds that are secreted into glandular trichomes, specialized structures found on leaf surfaces and anther appendages of flowers. The primary components of these trichome secretions are sesquiterpene lactones (STL), a diverse class of compounds produced abundantly by the plant family Compositae and believed to contribute to plant defense against herbivory. We treated wild and cultivated H. annuus accessions with exogenous methyl jasmonate, a plant hormone that mediates plant defense against insect herbivores and certain classes of fungal pathogens. The wild sunflower produced a higher density of glandular trichomes on its leaves than the cultivar. Comparison of the profiles of glandular trichome extracts obtained by liquid chromatography–mass spectroscopy (LC-MS) showed that wild and cultivated H. annuus were qualitatively similar in surface chemistry, although differing in the relative size and proportion of various compounds detected. Despite observing consistent transcriptional responses to methyl jasmonate treatment, we detected no significant effect on glandular trichome density or LC-MS profile in cultivated or wild sunflower, with wild sunflower exhibiting a declining trend in overall STL production and foliar glandular trichome density of jasmonate-treated plants. These results suggest that glandular trichomes and associated compounds may act as constitutive defenses or require greater levels of stimulus for induction than the observed transcriptional responses to exogenous jasmonate. Reduced defense investment in domesticated lines is consistent with predicted tradeoffs caused by selection for increased yield; future research will focus on the development of genetic resources to explicitly test the ecological roles of glandular trichomes and associated effects on plant growth and fitness
Chemical Diversity and Defence Metabolism: How Plants Cope with Pathogens and Ozone Pollution
Chemical defences represent a main trait of the plant innate immune system. Besides regulating the relationship between plants and their ecosystems, phytochemicals are involved both in resistance against pathogens and in tolerance towards abiotic stresses, such as atmospheric pollution. Plant defence metabolites arise from the main secondary metabolic routes, the phenylpropanoid, the isoprenoid and the alkaloid pathways. In plants, antibiotic compounds can be both preformed (phytoanticipins) and inducible (phytoalexins), the former including saponins, cyanogenic glycosides and glucosinolates. Chronic exposure to tropospheric ozone (O3) stimulates the carbon fluxes from the primary to the secondary metabolic pathways to a great extent, inducing a shift of the available resources in favour of the synthesis of secondary products. In some cases, the plant defence responses against pathogens and environmental pollutants may overlap, leading to the unspecific synthesis of similar molecules, such as phenylpropanoids. Exposure to ozone can also modify the pattern of biogenic volatile organic compounds (BVOC), emitted from plant in response to herbivore feeding, thus altering the tritrophic interaction among plant, phytophagy and their natural enemies. Finally, the synthesis of ethylene and polyamines can be regulated by ozone at level of S-adenosylmethionine (SAM), the biosynthetic precursor of both classes of hormones, which can, therefore, mutually inhibit their own biosynthesis with consequence on plant phenotype
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