15 research outputs found

    Urban Growth and Energy Supply in Africa: The Case of Ethiopia

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    Ethiopia is rapidly urbanising. Similar to other urban areas in developing countries, major issues in Ethiopia include a high level of income inequality, lack of formal employment opportunities and deeply rooted poverty, tenure insecurity, poor infrastructure, and limited access to electricity and energy. Frequently settlers end up in impoverished urban squatters and slums which do not offer them even the most basic infrastructure and hence lack to provide them with the perspectives they came for. Onward migration to farer off destinations such as the EU member states thus often remains as sole option for those caught in such urban poverty traps. Although the issue of informal urban settlements is not new to the context of Ethiopian cities, the current rapid urban growth rates are exposing urban rental markets as well as infrastructure and energy supply to considerable pressure. The paper investigates the respective situation in Ethiopia and demonstrates some best practice examples. In the context of Ethiopian cities, energy production and distribution have been highly centralised under state entities and the scope for exploring local/business driven and decentralised systems has been limited. Transitions can be implemented towards sustainability and the United Nations' Sustainable Development Goals if collective identification and structuring of issues along with collective envisioning of future is provoked or facilitated

    The Interactions of Sustainable Development Goals: The Case of Urban Informal Settlements in Ethiopia

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    Ethiopia is challenged by a strong development progress. Currently the major issues in Ethiopia, as a least developed country with a rapid urbanisation, include a high level of income inequality, lack of formal employment opportunities, deeply rooted poverty, tenure insecurity, poor infrastructure, and limited access to electricity and energy. The Erasmus+ Project "Social Inclusion and Energy Management for Informal Urban Settlements", enables European and Ethiopian universities to develop new university courses integrating the aspects of sustainability for future professionals in the field of architecture, urban planning but also social sciences. The paper investigates the respective situation in Ethiopia, and demonstrates the interactions of six selected Sustainable Development Goals of the United Nations highly linked with this topic. These six Sustainable Development Goals were identified in a participative process, involving different stakeholders like government officials, urban planners or informal settlers by interviews, focus groups, workshops and conferences. The focus is on SDG1 "No Poverty", SDG3 "Good Health and Well-being", SDG7 "Affordable and Clean Energy", SDG11 "Sustainable Cities and Communities", SDG13 "Climate Action" and SDG15 "Life on Land". In the context of Ethiopian cities, energy production and distribution have been highly centralised under state entities and the scope for exploring local/business driven and decentralised energy systems has been limited. Transitions can be implemented towards sustainability and the United Nations Sustainable Development Goals, if collective identification and structuring of issues along with collective envisioning of the future, and the interactions and trade-offs of different goals are taken into consideration

    Results of endoscopic transsphenoidal pituitary surgery in 40 patients with a growth hormone-secreting macroadenoma

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    Contains fulltext : 96290.pdf (Publisher’s version ) (Open Access)OBJECTIVE: Transsphenoidal pituitary surgery (TS) is the primary treatment of choice for patients with acromegaly. Macroadenomas (>1 cm) are more difficult to resect than microadenomas (remission rate +/- 50% compared to +/- 90%). Besides the conventional microscopic TS, the more recently introduced endoscopic technique is nowadays frequently used. However, no large series reporting on its results have yet been published. We evaluated the outcome of endoscopic TS in 40 patients with a growth hormone (GH)-secreting macroadenoma treated in our hospital between 1998 and 2007. METHODS: Medical records were retrospectively reviewed. Remission was defined as disappearance of clinical symptoms of acromegaly, normal serum insulin-like growth factor-1 levels (</=2 SD) and serum GH levels suppressed to <2 mU/l after an oral glucose tolerance test within the first 4 months after TS. RESULTS: In four patients TS aimed at debulking of the tumour. In the remaining 36 patients, remission was achieved in 20 patients. In the first 5 years remission was achieved in 6 out of 18 patients (33%) compared to 14 out of 22 patients (63%) in the following 5 years (p = 0.06). Thirteen patients had a mild perioperative complication. Before TS 15 patients received hormonal substitution therapy compared to 12 patients (33%) after TS. CONCLUSION: Endoscopic TS is a good primary therapeutic option for patients with a GH-secreting macroadenoma, resulting in a remission rate of up to 63% in experienced hands. This technique can potentially improve the outcome of TS in these patients

    b-tagging in DELPHI at LEP

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    Abstract: The standard method used for tagging b-hadrons in the DELPHI experiment at the CERN LEP Collider is discussed in detail. The main ingredient of b-tagging is the impact parameters of tracks, which relies mostly on the vertex detector. Additional information, such as the mass of particles associated to a secondary vertex, significantly improves the selection efficiency and the background suppression. The paper describes various discriminating variables used for the tagging and the procedure of their combination. In addition, applications of b-tagging to some physics analyses, which depend crucially on the performance and reliability of b-tagging, are described briefly

    Qualitätskultur. Ein Blick in die gelebte Praxis der Hochschulen. Beiträge zur 4. AQ Austria Jahrestagung 2016

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    Die Publikation zur AQ Austria Jahrestagung 2016 präsentiert in den einzelnen Beiträgen vielfältige Perspektiven, Ansätze, Beispiele und Erfahrungen mit Qualitätskultur und ermöglicht somit einen Blick in die gelebte Praxis der Qualitätskultur an Hochschulen. Die Frage, ob wir eine Qualitätskultur brauchen und was dafür oder dagegen spricht, [wird] in einleitenden Thesen [bearbeitet]. In fünf Foren wurden Kernfragen in Zusammenhang mit Zweck, Bedingungen und Ausgestaltung der Qualitätskultur diskutiert. Es geht u. a. um das Verständnis und den Stellenwert von Qualitätskultur ,das Wechselspiel mit internen und externen Rahmenbedingungen und um die Frage, wie Einstellungen und Werthaltungen der Mitarbeiterinnen und Mitarbeiter im Sinne einer Qualitätskultur gefördert werden können. Weitere Beiträge befassen sich mit dem Verhältnis von Qualitätskultur und externer Qualitätssicherung und damit, wie wirkungsvoll oder auch wirkungslos Qualitätskultur von Hochschulen eingeschätzt wird. (Autor

    Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease

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    Huntington's disease is a devastating neurodegenerative condition for which there is no therapy to slow disease progression. The particular vulnerability of striatal medium spiny neurons to Huntington's pathology is hypothesized to result from transcriptional dysregulation within the cAMP and CREB signaling cascades in these neurons. To test this hypothesis, and a potential therapeutic approach, we investigated whether inhibition of the striatal-specific cyclic nucleotide phosphodiesterase PDE10A would alleviate neurological deficits and brain pathology in a highly utilized model system, the R6/2 mouse
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