9 research outputs found

    Future prospects for personal security in travel by public transport

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    This work was supported by the Engineering and Physical Sciences Research Council [grant number EP/I037032/1]. No other funding support from any other bodies was provided.Peer reviewedPublisher PD

    Personal security in travel by public transport : the role of traveller information and associated technologies

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    Acknowledgement This research reported in this paper has been funded by a grant award from the Engineering and Physical Sciences Research Council: EP/I037032/1.Peer reviewedPublisher PD

    Scanning the European Ecosystem of Distributed Ledger Technologies for Social and Public Good: What, Why, Where, How, and Ways to Move Forward

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    Distributed Ledger Technologies (DLTs), such as blockchains, are primarily tamper-resistant and time-stamped databases. They allow multiple parties to record, verify and share data on a peer-to-peer basis across a network, in decentralised, synchronised and transparent ways, with limited human intervention and reduced intermediate steps. These technologies are mostly known for business use cases, from cryptocurrencies to asset track and tracing. But there are numerous organisations nowadays searching for alternative ways to harness the potential of DLTs in the pursuit of public and social good, from local to global challenges, and towards more inclusive, cooperative, sustainable, ethical or accountable digital and physical worlds. This Science for Policy report explores the current status of this particular field both theoretically and empirically, in the framework of the project #DLT4Good: Co-creating a European Ecosystem of DLTs for Social and Public Good. Part I offers a conceptual overview of the connections between main features of DLTs and their potential for social and public good goals. Emphasis is placed on different approaches to decentralisation, and on core building blocks of DLTs linked with values such as trust, privacy, self-sovereignty, autonomy, inclusiveness, transparency, openness, or the commons. Part II comprises a scanning of the current European ecosystem of DLT projects with activities in this field. It contains a summarized version of a database published online with 131 projects, and a quantitative review of main trends. It also includes a qualitative assessment of 10 projects selected from the larger sample to showcase this field and its diversity. Part III concludes with six independent position papers and recommendations from experts and advisors of the #DLT4Good project. The main topics addressed range from decentralized governance to collaborative economies, with highlights on issues such as trust, verifiability, transparency, privacy or bottom-up coordination.JRC.I.2-Foresight, Modelling, Behavioural Insights & Design for Polic

    Scanning the European Ecosystem of Distributed Ledger Technologies for Social and Public Good: What, Why, Where, How, and Ways to Move Forward

    Get PDF
    Distributed Ledger Technologies (DLTs), such as blockchains, are primarily tamper-resistant and time-stamped databases. They allow multiple parties to record, verify and share data on a peer-to-peer basis across a network, in decentralised, synchronised and transparent ways, with limited human intervention and reduced intermediate steps. These technologies are mostly known for business use cases, from cryptocurrencies to asset track and tracing. But there are numerous organisations nowadays searching for alternative ways to harness the potential of DLTs in the pursuit of public and social good, from local to global challenges, and towards more inclusive, cooperative, sustainable, ethical or accountable digital and physical worlds. This Science for Policy report explores the current status of this particular field both theoretically and empirically, in the framework of the project #DLT4Good: Co-creating a European Ecosystem of DLTs for Social and Public Good. Part One offers a conceptual overview of the connections between main features of DLTs and their potential for social and public good goals. Emphasis is placed on different approaches to decentralisation, and on core building blocks of DLTs linked with values such as trust, privacy, self-sovereignty, autonomy, inclusiveness, transparency, openness, or the commons. Part Two comprises a scanning of the current European ecosystem of DLT projects with activities in this field. It contains a summarized version of a database published online with 131 projects, and a quantitative review of main trends. It also includes a qualitative assessment of 10 projects selected from the larger sample to showcase this field and its diversity. Part Three concludes with six independent position papers and recommendations from experts and advisors of the #DLT4Good project. The main topics addressed range from decentralized governance to collaborative economies, with highlights on issues such as trust, verifiability, transparency, privacy or bottom-up coordination

    Convalescent plasma in patients admitted to hospital with COVID-19 (RECOVERY): a randomised controlled, open-label, platform trial

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    SummaryBackground Azithromycin has been proposed as a treatment for COVID-19 on the basis of its immunomodulatoryactions. We aimed to evaluate the safety and efficacy of azithromycin in patients admitted to hospital with COVID-19.Methods In this randomised, controlled, open-label, adaptive platform trial (Randomised Evaluation of COVID-19Therapy [RECOVERY]), several possible treatments were compared with usual care in patients admitted to hospitalwith COVID-19 in the UK. The trial is underway at 176 hospitals in the UK. Eligible and consenting patients wererandomly allocated to either usual standard of care alone or usual standard of care plus azithromycin 500 mg once perday by mouth or intravenously for 10 days or until discharge (or allocation to one of the other RECOVERY treatmentgroups). Patients were assigned via web-based simple (unstratified) randomisation with allocation concealment andwere twice as likely to be randomly assigned to usual care than to any of the active treatment groups. Participants andlocal study staff were not masked to the allocated treatment, but all others involved in the trial were masked to theoutcome data during the trial. The primary outcome was 28-day all-cause mortality, assessed in the intention-to-treatpopulation. The trial is registered with ISRCTN, 50189673, and ClinicalTrials.gov, NCT04381936.Findings Between April 7 and Nov 27, 2020, of 16 442 patients enrolled in the RECOVERY trial, 9433 (57%) wereeligible and 7763 were included in the assessment of azithromycin. The mean age of these study participants was65·3 years (SD 15·7) and approximately a third were women (2944 [38%] of 7763). 2582 patients were randomlyallocated to receive azithromycin and 5181 patients were randomly allocated to usual care alone. Overall,561 (22%) patients allocated to azithromycin and 1162 (22%) patients allocated to usual care died within 28 days(rate ratio 0·97, 95% CI 0·87–1·07; p=0·50). No significant difference was seen in duration of hospital stay (median10 days [IQR 5 to >28] vs 11 days [5 to >28]) or the proportion of patients discharged from hospital alive within 28 days(rate ratio 1·04, 95% CI 0·98–1·10; p=0·19). Among those not on invasive mechanical ventilation at baseline, nosignificant difference was seen in the proportion meeting the composite endpoint of invasive mechanical ventilationor death (risk ratio 0·95, 95% CI 0·87–1·03; p=0·24).Interpretation In patients admitted to hospital with COVID-19, azithromycin did not improve survival or otherprespecified clinical outcomes. Azithromycin use in patients admitted to hospital with COVID-19 should be restrictedto patients in whom there is a clear antimicrobial indication

    The governance of sustainable agriculture in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Politics at Massey University, Manawatū, New Zealand

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    The externalities associated with agriculture mean that a turn to sustainable farming practices by farmers is essential. However, those at the centre of such a turn have complex relationships to the structures of governance that regulate, order and control socio-economic life. Governance signals a shift to a wide range of governance mechanisms that are not anchored in the sovereign state and the mechanisms that regulate agriculture and the agrifood sector have changed significantly in recent years. This thesis [and briefly restate thesis question]. Drawing on two constructs from the theoretical and applied governance literature and the agrifood literature I examine farmer perceptions of hierarchy, the market and networks and the spatial locations of these new forms of governance in regard to biological farming practices. I conclude by arguing that there is a strong case for considering governance as the new way in which agriculture is regulated, controlled and influenced. At the forefront of this devolution of power away from central government is market-based regulation and control. The implications of such restructuring for the proliferation of sustainable agricultural practices means the strengthening of market instruments is needed to bolster sustainable farming. Furthermore, funding by central government is considered necessary by farmers in order to establish a strong case for the success of sustainable farming practices
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