Monitoring the Starvation-Survival Response of Edwardsiella piscicida and E. tarda in Freshwater Microcosms, at Various Temperatures

Edwardsiella piscicida is an important fish pathogen responsible for economic losses in global aquaculture, and E. tarda is also a human zoonotic pathogen. In this study, the survival of E. piscicida and E. tarda strains kept in filtered and sterilized lake water microcosms was investigated during a 20-week period at 7 ◦C, 15 ◦C and 25 ◦C, as well as its pathogenicity retention during a starvation period. E. tarda V43.2 stayed culturable for 6 weeks at 7 ◦C, 9 weeks at 25 ◦C and 12 weeks at 15 ◦C. Both E. piscicida strains (V12.1 and V57.2) stayed culturable even longer, for at least 12 weeks at 7 ◦C, 15 ◦C and 25 ◦C under the same starvation conditions. After Edwardsiella cells entered into the VBNC state, some became shorter and "rounded up," but others aggregated and retained a short rod shape. Aggregates of Edwardsiella cells were common throughout the VBNC period, and a well-formed biofilm was observed for all tested strains at the end of the experiment. The growth capacity of VBNC cells was restored by cultivating microcosm water samples in LB broth at 28 ◦C. Resuscitated E. piscicida cells were as virulent for the European eel as the controls. Natural waters can be a reservoir for Edwardsiella, and its underestimation in environmental samples poses a risk to public health and aquaculture

Micromón València (Universitat de València)

En Julio de 2017 se creó la red SWI@Spain, auspiciada por el grupo de Docencia y Difusión de la Microbiología (DDM) de la Sociedad Española de Microbiología (SEM), para desarrollar la iniciativa internacional Small World Initiative (SWI) en la península ibérica. En la Universitat de València (UV) se constituyó entonces el grupo de Innovación Docente en Microbiología (IDM) para implementar el proyecto a nivel local. Avalados por el Servei de Formació Permanent i Innovació Educativa (SFPIE) de la UV, el grupo ha llevado a cabo diferentes iniciativas relacionadas con el objetivo fundamental del proyecto: divulgar la problemática actual relacionada con el uso inadecuado de antibióticos, el incremento de bacterias resistentes a éstos y la necesidad de encontrar nuevas moléculas con actividad antibacteriana para combatir las infecciones que provocan

Predictive Power of the "Trigger Tool" for the detection of adverse events in general surgery: a multicenter observational validation study

Background In spite of the global implementation of standardized surgical safety checklists and evidence-based practices, general surgery remains associated with a high residual risk of preventable perioperative complications and adverse events. This study was designed to validate the hypothesis that a new “Trigger Tool” represents a sensitive predictor of adverse events in general surgery. Methods An observational multicenter validation study was performed among 31 hospitals in Spain. The previously described “Trigger Tool” based on 40 specific triggers was applied to validate the predictive power of predicting adverse events in the perioperative care of surgical patients. A prediction model was used by means of a binary logistic regression analysis. Results The prevalence of adverse events among a total of 1,132 surgical cases included in this study was 31.53%. The “Trigger Tool” had a sensitivity and specificity of 86.27% and 79.55% respectively for predicting these adverse events. A total of 12 selected triggers of overall 40 triggers were identified for optimizing the predictive power of the “Trigger Tool”. Conclusions The “Trigger Tool” has a high predictive capacity for predicting adverse events in surgical procedures. We recommend a revision of the original 40 triggers to 12 selected triggers to optimize the predictive power of this tool, which will have to be validated in future studies

Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study.

PURPOSE: As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19-free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS: This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a COVID-19-free surgical pathway (complete segregation of the operating theater, critical care, and inpatient ward areas) or no defined pathway (incomplete or no segregation, areas shared with patients with COVID-19). The primary outcome was 30-day postoperative pulmonary complications (pneumonia, acute respiratory distress syndrome, unexpected ventilation). RESULTS: Of 9,171 patients from 447 hospitals in 55 countries, 2,481 were operated on in COVID-19-free surgical pathways. Patients who underwent surgery within COVID-19-free surgical pathways were younger with fewer comorbidities than those in hospitals with no defined pathway but with similar proportions of major surgery. After adjustment, pulmonary complication rates were lower with COVID-19-free surgical pathways (2.2% v 4.9%; adjusted odds ratio [aOR], 0.62; 95% CI, 0.44 to 0.86). This was consistent in sensitivity analyses for low-risk patients (American Society of Anesthesiologists grade 1/2), propensity score-matched models, and patients with negative SARS-CoV-2 preoperative tests. The postoperative SARS-CoV-2 infection rate was also lower in COVID-19-free surgical pathways (2.1% v 3.6%; aOR, 0.53; 95% CI, 0.36 to 0.76). CONCLUSION: Within available resources, dedicated COVID-19-free surgical pathways should be established to provide safe elective cancer surgery during current and before future SARS-CoV-2 outbreaks

Pràctiques de Microbiologia

Aquest manual forma part dels materials oficials utilitzats en el marc de la Small World Initiative™ (SWI). Concebuda a la Universitat Yale (EUA) el 2012 per l’autora Jo Handelsman. SWI és un programa innovador dissenyat per a motivar els estudiants cap a l’elecció d’un grau en ciències experimentals, alhora que aborda una amenaça per a la salut a escala global: la reduïda disponibilitat d’antibiòtics eficaços. El programa SWI se centra sobre la idea d’un curs de biologia bàsica basada en el descobriment, en el qual estudiants de tot el món porten a terme treball de camp i investigació en el laboratori sobre mostres de sòl a la recerca de nous antibiòtics. Aquest aspecte és particularment rellevant, ja que dos terços dels antibiòtics disponibles procedeixen de bacteris o fongs aïllats dels sòls

Sustainability Committee Research: a Bibliometric Study

This study conducts a bibliometric analysis of research on sustainability committees. Specifically, our paper analyses the development of this field of research by identifying the most influential articles, authors, and relevant research themes, and highlighting potential future lines of research. Our sample is composed of the publications from the main collection of the Clarivate Analytics Web of Science database (WOS) for the period 1900–2021. Our findings stress the interdisciplinary nature of research about sustainability committees. In addition, our evidence emphasizes the need for more research to understand how firms respond to regulatory and societal pressures on sustainability matters. In addition, the network analysis highlights the main research themes and provides a basis for recognizing future research opportunities. Our paper is the first to perform a comprehensive bibliometric analysis for sustainability committees. Our evidence presents relevant implications for academics in the definition of their research project

La información narrativa de las empresas del Ibex 35: análisis del informe de gestión y del informe de resultados

Narrative corporate disclosures have become an important strategy for firms. The objective of this paper is to analyze textual information disclosed in management reports (MD&A) and annual earnings press releases from firms listed in Ibex 35 for the period 2018-2021. In particular, our study examines the tone and the length of the information contained in these documents. Our results point out that the information provided by Ibex 35 firms in management reports and earnings press releases remains mainly unbiased and is characterized by a low level of optimism and a high level of realism. In addition, our findings show insignificant differences in the tone of these disclosures that could have been determined by firm financial performance or by the year of analysis. However, the length of annual results reports and, especially of management reports, has significantly increased in the period of analysis, particularly in firms with lower financial performance.La información narrativa de los distintos documentos publicados por las empresas ha adquirido un papel importante en las estrategias de comunicación de estas. El objetivo de nuestro trabajo es analizar la información textual publicada en el informe de gestión y el informe de resultados de las empresas cotizadas en el Ibex 35 para el periodo 2018-2021. En particular, estudiamos el tono de la información publicada y la extensión de dichos documentos. Nuestros resultados ponen de manifiesto que las empresas del Ibex 35 no incorporan sesgos significativos en la información narrativa de informes de gestión e informes de resultados, que está marcada por un reducido nivel de optimismo y un alto nivel de realismo. Asimismo, tampoco se observan diferencias importantes en el tono de la información narrativa determinadas por el rendimiento económico de las empresas o por el año en el que se publican los documentos. Sin embargo, la extensión del informe de resultados y, especialmente de los informes de gestión, ha crecido significativamente en el periodo analizado, particularmente en las empresas con menor rendimiento

4255. Adaptación y capacitación de un espacio reducido y simulación en misiones helicopter emergency medical service (hems) para la adquisición de competencias clínicas y habilidades no técnicas

La simulación clínica en el medio helitransportado sanitario es todo un reto por sus características especiales. Dentro de la simulación la parte más importante es el Debriefing llevado a cabo por un instructor entrenado tras la simulación de cada caso clínico. Para ello se ha llevado a cabo un espacio reducido simulando el interior de un helicóptero. Tras la simulación y el Debriefing se ha pasado una evaluación del mismo mediante la herramienta Dash-Student versión larga, obteniendo unos resultados positivos, demostrado que el Debriefing es una herramienta potente que favorece la reflexión en la toma de decisiones y actuaciones dentro del entrenamiento en las misiones aerotransportadas sanitarias