12 research outputs found
Inducing malignant transformation of endometriosis in rats by longâterm sustaining hyperestrogenemia and type II
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Adsorption of eriochrome black T from aqueous phase on MgAl-, CoAl- and NiFe- calcined layered double hydroxides: Kinetic, equilibrium and thermodynamic studies
No full textStarch-NiFe-layered double hydroxide composites: Efficient removal of methyl orange from aqueous phase
No full textActivity and stability of the catalytic hydrogel membrane reactor for treating oxidized contaminants
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Neuroprotective effects of human mesenchymal stem cells on neural cultures exposed to 6-hydroxydopamine: implications for reparative therapy in Parkinsonâs disease
No full textMPTP: advances from an evergreen neurotoxin
No full textSince its discovery in 1976, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) models in rodents and nonhuman primates have continuously renewed to keep up with progresses of Parkinsonâs disease (PD) research. MPTP is able to reproduce almost all the clinical and neuropathological features of PD when administered to monkeys. In contrast, up to date no rodent model has been able
to reproduce all PD features in one. Nevertheless, MPTP is a very versatile neurotoxin that can reproduce different aspects of PD pathology, depending upon the dose and regimen of administration. At the present time, a number of different MPTP models have been developed, allowing researchers to investigate either the classical PD neuropathology and neuroprotective mechanisms or
known pathological processes underlining more recently discovered aspects of the disease, such as nonmotor symptoms. In this chapter primate and rodent MPTP models are reviewed, focusing mainly on the contribution that different MPTP protocols can offer to reproduce the multifaceted aspects of the disease
Structure, nomenclature and viable synthesis of micro/nanoscale metal organic frameworks and their remarkable applications in adsorption of organic pollutants
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