Trunk sway in mildly disabled multiple sclerosis patients with and without balance impairment

Multiple sclerosis (MS) causes a broad range of neurological symptoms. Most common is poor balance control. However, knowledge of deficient balance control in mildly affected MS patients who are complaining of balance impairment but have normal clinical balance tests (CBT) is limited. This knowledge might provide insights into the normal and pathophysiological mechanisms underlying stance and gait. We analysed differences in trunk sway between mildly disabled MS patients with and without subjective balance impairment (SBI), all with normal CBT. The sway was measured for a battery of stance and gait balance tests (static and dynamic posturography) and compared to that of age- and sex-matched healthy subjects. Eight of 21 patients (38%) with an Expanded Disability Status Scale of 1.0-3.0 complained of SBI during daily activities. For standing on both legs with eyes closed on a normal and on a foam surface, patients in the no SBI group showed significant differences in the range of trunk roll (lateral) sway angle and velocity, compared to normal persons. Patients in the SBI group had significantly greater lateral sway than the no SBI group, and sway was also greater than normal in the pitch (anterior-posterior) direction. Sway for one-legged stance on foam was also greater in the SBI group compared to the no SBI and normal groups. We found a specific laterally directed impairment of balance in all patients, consistent with a deficit in proprioceptive processing, which was greater in the SBI group than in the no SBI group. This finding most likely explains the subjective symptoms of imbalance in patients with MS with normal CBT

The VIPERS Multi-Lambda Survey. I. UV and NIR Observations, multi-color catalogues and photometric redshifts

We present observations collected in the CFHTLS-VIPERS region in the ultraviolet (UV) with the GALEX satellite (far and near UV channels) and the near infrared with the CFHT/WIRCam camera ($K_s$-band) over an area of 22 and 27 deg$^2$, respectively. The depth of the photometry was optimized to measure the physical properties (e.g., SFR, stellar masses) of all the galaxies in the VIPERS spectroscopic survey. The large volume explored by VIPERS will enable a unique investigation of the relationship between the galaxy properties and their environment (density field and cosmic web) at high redshift (0.5 < z < 1.2). In this paper, we present the observations, the data reductions and the build-up of the multi-color catalogues. The CFHTLS-T0007 (gri-{\chi}^2) images are used as reference to detect and measure the $K_s$-band photometry, while the T0007 u-selected sources are used as priors to perform the GALEX photometry based on a dedicated software (EMphot). Our final sample reaches $NUV_{AB}$~25 (at 5{\sigma}) and $K_{AB}$~22 (at 3{\sigma}). The large spectroscopic sample (~51,000 spectroscopic redshifts) allows us to highlight the robustness of our star/galaxy separation, and the reliability of our photometric redshifts with a typical accuracy $\sigma_z \le$ 0.04 and a catastrophic failure rate {\eta} < 2% down to i~23. We present various tests on the $K_s$ band completeness and photometric redshift accuracy by comparing with existing, overlapping deep photometric catalogues. Finally, we discuss the BzK sample of passive and active galaxies at high redshift and the evolution of galaxy morphology in the (NUV-r) vs (r-K_s) diagram at low redshift (z < 0.25) thanks to the high image quality of the CFHTLS. The images, catalogues and photometric redshifts for 1.5 million sources (down to $NUV \le$ 25 or $K_s \le$ 22) are released and available at this URL: http://cesam.lam.fr/vipers-mls/Comment: 14 pages, 16 figures. Accepted for publication in A&A. Version to be publishe

First Detection of Polarization of the Submillimetre Diffuse Galactic Dust Emission by Archeops

We present the first determination of the Galactic polarized emission at 353 GHz by Archeops. The data were taken during the Arctic night of February 7, 2002 after the balloon--borne instrument was launched by CNES from the Swedish Esrange base near Kiruna. In addition to the 143 GHz and 217 GHz frequency bands dedicated to CMB studies, Archeops had one 545 GHz and six 353 GHz bolometers mounted in three polarization sensitive pairs that were used for Galactic foreground studies. We present maps of the I, Q, U Stokes parameters over 17% of the sky and with a 13 arcmin resolution at 353 GHz (850 microns). They show a significant Galactic large scale polarized emission coherent on the longitude ranges [100, 120] and [180, 200] deg. with a degree of polarization at the level of 4-5%, in agreement with expectations from starlight polarization measurements. Some regions in the Galactic plane (Gem OB1, Cassiopeia) show an even stronger degree of polarization in the range 10-20%. Those findings provide strong evidence for a powerful grain alignment mechanism throughout the interstellar medium and a coherent magnetic field coplanar to the Galactic plane. This magnetic field pervades even some dense clouds. Extrapolated to high Galactic latitude, these results indicate that interstellar dust polarized emission is the major foreground for PLANCK-HFI CMB polarization measurement.Comment: Submitted to Astron. & Astrophys., 14 pages, 12 Fig., 2 Table

SpineCreator: a Graphical User Interface for the Creation of Layered Neural Models.

There is a growing requirement in computational neuroscience for tools that permit collaborative model building, model sharing, combining existing models into a larger system (multi-scale model integration), and are able to simulate models using a variety of simulation engines and hardware platforms. Layered XML model specification formats solve many of these problems, however they are difficult to write and visualise without tools. Here we describe a new graphical software tool, SpineCreator, which facilitates the creation and visualisation of layered models of point spiking neurons or rate coded neurons without requiring the need for programming. We demonstrate the tool through the reproduction and visualisation of published models and show simulation results using code generation interfaced directly into SpineCreator. As a unique application for the graphical creation of neural networks, SpineCreator represents an important step forward for neuronal modelling

QUBIC: The QU Bolometric Interferometer for Cosmology

One of the major challenges of modern cosmology is the detection of B-mode polarization anisotropies in the CMB. These originate from tensor fluctuations of the metric produced during the inflationary phase. Their detection would therefore constitute a major step towards understanding the primordial Universe. The expected level of these anisotropies is however so small that it requires a new generation of instruments with high sensitivity and extremely good control of systematic effects. We propose the QUBIC instrument based on the novel concept of bolometric interferometry, bringing together the sensitivity advantages of bolometric detectors with the systematics effects advantages of interferometry. Methods: The instrument will directly observe the sky through an array of entry horns whose signals will be combined together using an optical combiner. The whole set-up is located inside a cryostat. Polarization modulation will be achieved using a rotating half-wave plate and interference fringes will be imaged on two focal planes (separated by a polarizing grid) tiled with bolometers. We show that QUBIC can be considered as a synthetic imager, exactly similar to a usual imager but with a synthesized beam formed by the array of entry horns. Scanning the sky provides an additional modulation of the signal and improve the sky coverage shape. The usual techniques of map-making and power spectrum estimation can then be applied. We show that the sensitivity of such an instrument is comparable with that of an imager with the same number of horns. We anticipate a low level of beam-related systematics thanks to the fact that the synthesized beam is determined by the location of the primary horns. Other systematics should be under good control thanks to an autocalibration technique, specific to our concept, that will permit the accurate determination of most of the systematics parameters.Comment: 12 pages, 10 figures, submitted to Astronomy and Astrophysic

Using insights from (public) services management to improve student engagement in higher education

This paper argues that current approaches used to assess and monitor student engagement in UK higher education are failing to fulfil their potential by superficially helping institutions to appear professional and innovative yet failing to accurately measure and improve engagement. Drawing on service management literature including (Public) Service Dominant theory, this paper argues that current strategies are failing to deliver for three main reasons. They do not capture the full value students derive from their engagement experience, they underplay the impact of peers within the ecosystem and they do not effectively engage employees. The paper concludes by exploring the implications of these omissions for further research and practice

Prime Focus Spectrograph (PFS) for the Subaru Telescope: Overview, recent progress, and future perspectives

PFS (Prime Focus Spectrograph), a next generation facility instrument on the 8.2-meter Subaru Telescope, is a very wide-field, massively multiplexed, optical and near-infrared spectrograph. Exploiting the Subaru prime focus, 2394 reconfigurable fibers will be distributed over the 1.3 deg field of view. The spectrograph has been designed with 3 arms of blue, red, and near-infrared cameras to simultaneously observe spectra from 380nm to 1260nm in one exposure at a resolution of ~1.6-2.7A. An international collaboration is developing this instrument under the initiative of Kavli IPMU. The project is now going into the construction phase aiming at undertaking system integration in 2017-2018 and subsequently carrying out engineering operations in 2018-2019. This article gives an overview of the instrument, current project status and future paths forward.Comment: 17 pages, 10 figures. Proceeding of SPIE Astronomical Telescopes and Instrumentation 201

Temperature and polarization angular power spectra of Galactic dust radiation at 353 GHz as measured by Archeops

We present the first measurement of temperature and polarization angular power spectra of the diffuse emission of Galactic dust at 353 GHz as seen by Archeops on 20% of the sky. The temperature angular power spectrum is compatible with that provided by the extrapolation to 353 GHz of IRAS and DIRBE maps using \cite{fds} model number 8. For Galactic latitudes $|b| \geq 5$ deg we report a 4 sigma detection of large scale ($3\leq \ell \leq 8$) temperature-polarization cross-correlation $(\ell+1)C_\ell^{TE}/2\pi = 76\pm 21 \mu\rm{K_{RJ}}^2$ and set upper limits to the $E$ and $B$ modes at $11 \mu\rm{K_{RJ}}^2$. For Galactic latitudes $|b| \geq 10$ deg, on the same angular scales, we report a 2 sigma detection of temperature-polarization cross-correlation $(\ell+1)C_\ell^{TE}/2\pi = 24\pm 13 \mu\rm{K_{RJ}}^2$. These results are then extrapolated to 100 GHz to estimate the contamination in CMB measurements by polarized diffuse Galactic dust emission. The $TE$ signal is then $1.7\pm0.5$ and $0.5\pm0.3 \mu\rm{K^2_{CMB}}$ for $|b| \geq 5$ and 10 deg. respectively. The upper limit on $E$ and $B$ becomes $0.2 \mu\rm{K^2_{CMB}} (2\sigma)$. If polarized dust emission at higher Galactic latitude cuts is similar to the one we report here, then dust polarized radiation will be a major foreground for determining the polarization power spectra of the CMB at high frequencies above 100 GHz.Comment: 11 pages, 8 figures, submitted to A

The Cosmic Microwave Background Anisotropy Power Spectrum measured by Archeops

We present a determination by the Archeops experiment of the angular power spectrum of the cosmic microwave background anisotropy in 16 bins over the multipole range l=15-350. Archeops was conceived as a precursor of the Planck HFI instrument by using the same optical design and the same technology for the detectors and their cooling. Archeops is a balloon-borne instrument consisting of a 1.5 m aperture diameter telescope and an array of 21 photometers maintained at ~100 mK that are operating in 4 frequency bands centered at 143, 217, 353 and 545 GHz. The data were taken during the Arctic night of February 7, 2002 after the instrument was launched by CNES from Esrange base (Sweden). The entire data cover ~ 30% of the sky.This first analysis was obtained with a small subset of the dataset using the most sensitive photometer in each CMB band (143 and 217 GHz) and 12.6% of the sky at galactic latitudes above 30 degrees where the foreground contamination is measured to be negligible. The large sky coverage and medium resolution (better than 15 arcminutes) provide for the first time a high signal-to-noise ratio determination of the power spectrum over angular scales that include both the first acoustic peak and scales probed by COBE/DMR. With a binning of Delta(l)=7 to 25 the error bars are dominated by sample variance for l below 200. A companion paper details the cosmological implications.Comment: A&A Letter, in press, 6 pages, 4 figures, see also http://www.archeops.or