12 research outputs found

    Bolsa de estudos universitários para professores de escola no Perú: uma experiência de colaboração público-privada, além da responsabilidade social universitária

    Get PDF
    The current university organizations have assumed responsibility for the connection between the university and society and promote the process of public-private agreements, as developed between the Pontifical Catholic University of Peru (PUCP) and the National Scholarship and Educational Credit Program (PRONABEC) of the Government of Peru, in order to promote, and develop, their experience in the training of teachers of the Public School Magisterial in order to improve the teaching performance and the quality of learning in students.This article presents some guidelines developed during the execution of the President of the Republic Scholarship (2014-2015) and which in various ways explain the vocation of service and commitment to educational development, which PUCP has been carrying out since its founding as a university institution.In this regard, the University devoted resources and resources beyond what was agreed in the signed agreements, assuming the mission as a proper process of University Social Responsibility (USR) in a positive experience that far exceeded the expectations projected for the benefit of educational quality of teachers and students of the country.Las organizaciones universitarias, como la Pontificia Universidad Católica del Perú (PUCP), han asumido con responsabilidad la labor de conexión entre la universidad y la sociedad y promueven el proceso de convenios público privados, como el desarrollado con el Programa Nacional de Becas y Crédito Educativo del Perú (Pronabec), para favorecer y desarrollar su experiencia en capacitación de docentes de la Carrera Pública Magisterial con el fin de mejorar los rendimientos docentes y así contribuir a la calidad educativa de los aprendizajes.La Beca Docente Presidente de la República contribuyó en la formación personal y académica de docentes de la carrera pública magisterial peruana, quienes, a través de un concurso de mérito, accedieron a conformar una elite de profesionales que se benefició de la valiosa contribución que aportaron las universidades participantes del proyecto, en especial, la Pontificia Universidad Católica del Perú, que puso a disposición de los alumnos becarios de Maestría, las competencias y capacidades que exige la educación y sociedad actuales. En ese propósito, se destinaron esfuerzos y recursos más allá de lo estipulado en los Convenios marco firmados, asumiendo la misión encomendada como un proceso propio de responsabilidad social universitaria (RSU) en una positiva experiencia que superó, largamente, las expectativas proyectadas, en beneficio de la calidad educativa de amplios sectores del país.Organizações universitários atuais, assumiram a responsabilidade pelo trabalho de ligação entre a universidade ea sociedade e promover o processo de parcerias público-privadas como desenvolvido entre a Pontifícia Universidade Católica do Peru (PUCP) com o Programa Nacional de Bolsas de Estudo e Crédito Educativo do Peru (PRONABEC) do Governo do Peru, para promover e desenvolver a sua experiência na formação de professores de Educador Pública, a fim de melhorar o desempenho educacional e qualidade do ensino da aprendizagem dos alunos.Este artigo apresenta algumas orientações desenvolvidas durante a execução do Bolsa de estudos Presidente da República (2014-2015) e de várias maneiras explicar a vocação de serviço e compromisso com o desenvolvimento educacional, a PUCP tem vindo a fazer desde a sua fundação como universidade. Nesse propósito da universidade, esforços e recursos para além do que foi acordado nos acordos assinados dedicado, assumindo a missão de si um processo de Responsabilidade Social Universitária (RSU) em uma experiência positiva que excedeu longa expectativas projetadas para o benefício da qualidade da educação de professores e alunos em todo o país

    Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

    Get PDF
    Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

    Gestión del conocimiento. Perspectiva multidisciplinaria. Volumen 17

    Get PDF
    El libro “Gestión del Conocimiento. Perspectiva Multidisciplinaria”, Volumen 17 de la Colección Unión Global, es resultado de investigaciones. Los capítulos del libro, son resultados de investigaciones desarrolladas por sus autores. El libro es una publicación internacional, seriada, continua, arbitrada, de acceso abierto a todas las áreas del conocimiento, orientada a contribuir con procesos de gestión del conocimiento científico, tecnológico y humanístico. Con esta colección, se aspira contribuir con el cultivo, la comprensión, la recopilación y la apropiación social del conocimiento en cuanto a patrimonio intangible de la humanidad, con el propósito de hacer aportes con la transformación de las relaciones socioculturales que sustentan la construcción social de los saberes y su reconocimiento como bien público

    Beca docente en el Perú: una experiencia de colaboración público privada, más allá de la responsabilidad social universitaria

    No full text
    The current university organizations have assumed responsibility for the connection between the university and society and promote the process of public-private agreements, as developed between the Pontifical Catholic University of Peru (PUCP) and the National Scholarship and Educational Credit Program (PRONABEC) of the Government of Peru, in order to promote, and develop, their experience in the training of teachers of the Public School Magisterial in order to improve the teaching performance and the quality of learning in students.This article presents some guidelines developed during the execution of the President of the Republic Scholarship (2014-2015) and which in various ways explain the vocation of service and commitment to educational development, which PUCP has been carrying out since its founding as a university institution.In this regard, the University devoted resources and resources beyond what was agreed in the signed agreements, assuming the mission as a proper process of University Social Responsibility (USR) in a positive experience that far exceeded the expectations projected for the benefit of educational quality of teachers and students of the country.Organizações universitários atuais, assumiram a responsabilidade pelo trabalho de ligação entre a universidade ea sociedade e promover o processo de parcerias público-privadas como desenvolvido entre a Pontifícia Universidade Católica do Peru (PUCP) com o Programa Nacional de Bolsas de Estudo e Crédito Educativo do Peru (PRONABEC) do Governo do Peru, para promover e desenvolver a sua experiência na formação de professores de Educador Pública, a fim de melhorar o desempenho educacional e qualidade do ensino da aprendizagem dos alunos.Este artigo apresenta algumas orientações desenvolvidas durante a execução do Bolsa de estudos Presidente da República (2014-2015) e de várias maneiras explicar a vocação de serviço e compromisso com o desenvolvimento educacional, a PUCP tem vindo a fazer desde a sua fundação como universidade. Nesse propósito da universidade, esforços e recursos para além do que foi acordado nos acordos assinados dedicado, assumindo a missão de si um processo de Responsabilidade Social Universitária (RSU) em uma experiência positiva que excedeu longa expectativas projetadas para o benefício da qualidade da educação de professores e alunos em todo o país.Las organizaciones universitarias, como la Pontificia Universidad Católica del Perú (PUCP), han asumido con responsabilidad la labor de conexión entre la universidad y la sociedad y promueven el proceso de convenios público privados, como el desarrollado con el Programa Nacional de Becas y Crédito Educativo del Perú (Pronabec), para favorecer y desarrollar su experiencia en capacitación de docentes de la Carrera Pública Magisterial con el fin de mejorar los rendimientos docentes y así contribuir a la calidad educativa de los aprendizajes.La Beca Docente Presidente de la República contribuyó en la formación personal y académica de docentes de la carrera pública magisterial peruana, quienes, a través de un concurso de mérito, accedieron a conformar una elite de profesionales que se benefició de la valiosa contribución que aportaron las universidades participantes del proyecto, en especial, la Pontificia Universidad Católica del Perú, que puso a disposición de los alumnos becarios de Maestría, las competencias y capacidades que exige la educación y sociedad actuales. En ese propósito, se destinaron esfuerzos y recursos más allá de lo estipulado en los Convenios marco firmados, asumiendo la misión encomendada como un proceso propio de responsabilidad social universitaria (RSU) en una positiva experiencia que superó, largamente, las expectativas proyectadas, en beneficio de la calidad educativa de amplios sectores del país

    Dietary constituents: relationship with breast cancer prognostic (MCC-SPAIN Follow-Up)

    Get PDF
    The aim of this study was to characterize the relationship between the intake of the major nutrients and prognosis in breast cancer. A cohort based on 1350 women with invasive (stage I-IV) breast cancer (BC) was followed up. Information about their dietary habits before diagnosis was collected using a semi-quantitative Food Frequency Questionnaire. Participants without FFQ or with implausible energy intake were excluded. The total amount consumed of each nutrient (Kcal/day) was divided into tertiles, considering as "high intakes" those above third tertile. The main effect studied was overall survival. Cox regression was used to assess the association between death and nutrient intake. During a median follow-up of 6.5 years, 171 deaths were observed. None of the nutrients analysed was associated with mortality in the whole sample. However, in normal-weight women (BMI 18.5-25 kg/m2) a high intake of carbohydrates (≥809 Kcal/day), specifically monosaccharides (≥468 Kcal/day), worsened prognostic compared to lowest (≤352 Kcal/day). Hazard Ratios (HRs) for increasing tertiles of intake were HR:2.22 95% CI (1.04 to 4.72) and HR:2.59 95% CI (1.04 to 6.48), respectively (p trend = 0.04)). Conversely, high intakes of polyunsaturated fats (≥135 Kcal/day) improved global survival (HR: 0.39 95% CI (0.15 to 1.02) p-trend = 0.05) compared to the lowest (≤92.8 kcal/day). In addition, a protective effect was found substituting 100 kcal of carbohydrates with 100 kcal of fats in normal-weight women (HR: 0.76 95% CI (0.59 to 0.98)). Likewise, in premenopausal women a high intake of fats (≥811 Kcal/day) showed a protective effect (HR:0.20 95% CI (0.04 to 0.98) p trend = 0.06). Finally, in Estrogen Receptors (ER) negative tumors, we found a protective effect of high intake of animal proteins (≥238 Kcal/day, HR: 0.24 95% CI (0.06 to 0.98). According to our results, menopausal status, BMI and ER status could play a role in the relationship between diet and BC survival and must be taken into account when studying the influence of different nutrients

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain

    No full text
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation of CRC with H. pylori seropositivity and with seropositivity to 16 H. pylori proteins, in the MultiCase-Control study, MCC-Spain.Methods: MCC-Spain is a multicase-control study carried out in Spain from 2008 to 2013. In total, 2,140 histologically-confirmed incident CRC cases and 4,098 population-based controls were recruited. Controls were frequency-matched by sex, age, and province. Epidemiological data were collected through a questionnaire fulfilled by face-to-face interviews and a self-administered food-frequency questionnaire. Seroreactivities against 16 H. pylori proteins were determined in 1,488 cases and 2,495 controls using H. pylori multiplex serology. H. pylori seropositivity was defined as positivity to >= 4 proteins. Multivariable logistic regression mixed models were used to estimate odds ratios (OR) and 95% confidence intervals (CI).Results: H. pylori seropositivity was not associated with increased CRC risk (OR = 0.91; 95% CI: 0.71-1.16). Among H. pylori seropositive subjects, seropositivity to Cag delta showed a lower CRC risk, and risk decreased with increasing number of proteins seropositive. Seropositivity to the most recognized virulence factors, CagA and VacA, was not associated with a higher CRC risk. No statistically significant heterogeneity was identified among tumor sites, although inverse relations were stronger for left colon cancer. An interaction with age and sex was found: H. pylori seropositivity was associated with a lower CRC risk in men younger than 65 and with a higher risk in older women.Conclusions: Our results suggest that neither H. pylori seropositivity, nor seropositivity to the virulence factor CagA are associated with a higher CRC risk. A possible effect modification by age and sex was identified

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain

    No full text
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation of CRC with H. pylori seropositivity and with seropositivity to 16 H. pylori proteins, in the MultiCase-Control study, MCC-Spain. Methods: MCC-Spain is a multicase-control study carried out in Spain from 2008 to 2013. In total, 2,140 histologically-confirmed incident CRC cases and 4,098 population-based controls were recruited. Controls were frequency-matched by sex, age, and province. Epidemiological data were collected through a questionnaire fulfilled by face-to-face interviews and a self-administered food-frequency questionnaire. Seroreactivities against 16 H. pylori proteins were determined in 1,488 cases and 2,495 controls using H. pylori multiplex serology. H. pylori seropositivity was defined as positivity to >/=4 proteins. Multivariable logistic regression mixed models were used to estimate odds ratios (OR) and 95% confidence intervals (CI). Results:H. pylori seropositivity was not associated with increased CRC risk (OR = 0.91; 95% CI: 0.71-1.16). Among H. pylori seropositive subjects, seropositivity to Cagdelta showed a lower CRC risk, and risk decreased with increasing number of proteins seropositive. Seropositivity to the most recognized virulence factors, CagA and VacA, was not associated with a higher CRC risk. No statistically significant heterogeneity was identified among tumor sites, although inverse relations were stronger for left colon cancer. An interaction with age and sex was found: H. pylori seropositivity was associated with a lower CRC risk in men younger than 65 and with a higher risk in older women. Conclusions: Our results suggest that neither H. pylori seropositivity, nor seropositivity to the virulence factor CagA are associated with a higher CRC risk. A possible effect modification by age and sex was identified

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain

    No full text
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation of CRC with H. pylori seropositivity and with seropositivity to 16 H. pylori proteins, in the MultiCase-Control study, MCC-Spain.Methods: MCC-Spain is a multicase-control study carried out in Spain from 2008 to 2013. In total, 2,140 histologically-confirmed incident CRC cases and 4,098 population-based controls were recruited. Controls were frequency-matched by sex, age, and province. Epidemiological data were collected through a questionnaire fulfilled by face-to-face interviews and a self-administered food-frequency questionnaire. Seroreactivities against 16 H. pylori proteins were determined in 1,488 cases and 2,495 controls using H. pylori multiplex serology. H. pylori seropositivity was defined as positivity to >= 4 proteins. Multivariable logistic regression mixed models were used to estimate odds ratios (OR) and 95% confidence intervals (CI).Results: H. pylori seropositivity was not associated with increased CRC risk (OR = 0.91; 95% CI: 0.71-1.16). Among H. pylori seropositive subjects, seropositivity to Cag delta showed a lower CRC risk, and risk decreased with increasing number of proteins seropositive. Seropositivity to the most recognized virulence factors, CagA and VacA, was not associated with a higher CRC risk. No statistically significant heterogeneity was identified among tumor sites, although inverse relations were stronger for left colon cancer. An interaction with age and sex was found: H. pylori seropositivity was associated with a lower CRC risk in men younger than 65 and with a higher risk in older women.Conclusions: Our results suggest that neither H. pylori seropositivity, nor seropositivity to the virulence factor CagA are associated with a higher CRC risk. A possible effect modification by age and sex was identified

    Helicobacter pylori Antibody Reactivities and Colorectal Cancer Risk in a Case-control Study in Spain

    Get PDF
    Background: Several studies have suggested that Helicobacter pylori (H. pylori) infection is a risk factor for colorectal cancer (CRC), while others have not confirmed this hypothesis. This work aimed to assess the relation of CRC with H. pylori seropositivity and with seropositivity to 16 H. pylori proteins, in the MultiCase-Control study, MCC-Spain. Methods: MCC-Spain is a multicase-control study carried out in Spain from 2008 to 2013. In total, 2,140 histologically-confirmed incident CRC cases and 4,098 population-based controls were recruited. Controls were frequency-matched by sex, age, and province. Epidemiological data were collected through a questionnaire fulfilled by face-to-face interviews and a self-administered food-frequency questionnaire. Seroreactivities against 16 H. pylori proteins were determined in 1,488 cases and 2,495 controls using H. pylori multiplex serology. H. pylori seropositivity was defined as positivity to ≥4 proteins. Multivariable logistic regression mixed models were used to estimate odds ratios (OR) and 95% confidence intervals (CI). Results:H. pylori seropositivity was not associated with increased CRC risk (OR = 0.91; 95% CI: 0.71-1.16). Among H. pylori seropositive subjects, seropositivity to Cagδ showed a lower CRC risk, and risk decreased with increasing number of proteins seropositive. Seropositivity to the most recognized virulence factors, CagA and VacA, was not associated with a higher CRC risk. No statistically significant heterogeneity was identified among tumor sites, although inverse relations were stronger for left colon cancer. An interaction with age and sex was found: H. pylori seropositivity was associated with a lower CRC risk in men younger than 65 and with a higher risk in older women. Conclusions: Our results suggest that neither H. pylori seropositivity, nor seropositivity to the virulence factor CagA are associated with a higher CRC risk. A possible effect modification by age and sex was identified
    corecore