N-[(E)-3,4-Dimeth­oxy­benzyl­idene]-2,3-dimethyl­aniline

In the title compound, C17H19NO2, the aromatic rings are oriented at a dihedral angle of 59.27 (12)°. In the crystal, inversion dimers linked by pairs of weak C—H⋯O inter­actions generate R 2 2(12) loops

Dimethyl (2-hydr­oxy-4-phenyl­but-3-en-2-yl)phospho­nate

In the title compound, C12H17O4P, the phenyl­butenyl group is disordered over two sets of sites with an occupancy ratio of 0.755 (12):0.245 (12). In the crystal, inversion dimers linked by pairs of O—H⋯O hydrogen bonds occur, forming R 2 2(10) ring motifs. The packing is consolidated by weak C—H⋯π inter­actions

5-[(E)-(2-Fluoro­benzyl­idene)amino]-2-hy­droxy­benzoic acid

In the title compound, C14H10FNO3, the dihedral angle between the two benzene rings is 32.66 (14)°. An S(6) ring motif is formed due to an intra­molecular O—H⋯O hydrogen bond between the hy­droxy and carbonyl groups. In the crystal, mol­ecules are consolidated into dimers with R 2 2(8) ring motifs by pairs of O—H⋯O hydrogen bonds

N-[(E)-2,4-Dichloro­benzyl­idene]-4-methyl­aniline

In the title compound, C14H11Cl2N, the dihedral angle between the 4-methyl­anilinic and 2,4-dichloro­benzaldehyde moieties is 7.37 (8)°. In the crystal, C—H⋯π inter­actions between the terminal methyl group and a symmetry-related ring of the anilinic group help to establish the packing

4-Chloro-N-[(E)-(3,4-dimeth­oxy­phen­yl)methyl­idene]aniline

The asymmetric unit of the title compound, C15H14ClNO2, contains two mol­ecules with significantly different conformations: the dihedral angles between the 4-chloro­aniline and 3,4-dimeth­oxy­phenyl (excluding C atoms) moieties are 19.68 (7) and 45.54 (4)°. In the crystal, the mol­ecules are linked by C—H⋯O hydrogen bonds and weak C—H⋯π inter­actions

Dimethyl (1-hydr­oxy-1,2-diphenyl­ethyl)phospho­nate

In the mol­ecule of the title compound, C16H19O4P, the coordination around the P atom is distorted tetra­hedral. The aromatic rings are oriented at a dihedral angle of 72.28 (11)°. Intra­molecular C—H⋯O hydrogen bonding result in the formation of five- and six-membered rings. In the crystal structure, inter­molecular C—H⋯O hydrogen bonds link the mol­ecules. There is also a weak C—H⋯π inter­action

Orientation Independent Chipless RFID Tag Using Novel Trefoil Resonators

In this paper, a compact and fully passive bit encoding circuit, capable of operating as a chipless radio frequency identification (RFID) tag is presented. The structure consists of novel concentric trefoil-shaped slot resonators realized using Rogers RT/duroid (R) 5880 laminate, occupying a physical footprint of 13.55 x 13.55 mm(2). Each resonating element is associated with a particular data bit, having a 1:1 resonator-to-bit correspondence. Bit sequences are configured through introducing modifications in the geometric structure either by addition or exclusion of each nested slot resonator. Such changes manifest directly in the electromagnetic signature of the tag as presence or absence of corresponding resonant peaks. The proposed 10-bit tag offers minimized inter-resonator mutual coupling and insensitivity to changes in polarization and incident angles thereby demonstrating orientation independent functionality. Moreover, error-free encoding is achieved through stabilizing the shift in resonant frequencies for a variety of different geometric configurations and orientation of the structure. The tag operates within the license-free ultrawideband ranging from 5.4 to 10.4 GHz, providing spectral bit capacity and bit density of 2 bits/GHz and 5.44 bits/cm(2) respectively

Orientation independent chipless RFID tag using novel trefoil resonators

In this paper, a compact and fully passive bit encoding circuit, capable of operating as a chipless radio frequency identification (RFID) tag is presented. The structure consists of novel concentric trefoil-shaped slot resonators realized using Rogers RT/duroid 5880 laminate, occupying a physical footprint of 13.55 $\times$13.55 mm^2. Each resonating element is associated with a particular data bit, having a 1:1 resonator-to-bit correspondence. Bit sequences are configured through introducing modifications in the geometric structure either by addition or exclusion of each nested slot resonator. Such changes manifest directly in the electromagnetic signature of the tag as presence or absence of corresponding resonant peaks. The proposed 10-bit tag offers minimized inter-resonator mutual coupling and insensitivity to changes in polarization and incident angles thereby demonstrating orientation independent functionality. Moreover, error-free encoding is achieved through stabilizing the shift in resonant frequencies for a variety of different geometric configurations and orientation of the structure. The tag operates within the license-free ultra-wideband ranging from 5.4 to 10.4 GHz, providing spectral bit capacity and bit density of 2 bits/GHz and 5.44 bits/cm^2 respectively

The learners' perspective on internal medicine ward rounds: a cross-sectional study

<p>Abstract</p> <p>Background</p> <p>Ward rounds form an integral part of Internal Medicine teaching. This study aimed to determine the trainees' opinions regarding various aspects of their ward rounds, including how well they cover their learning needs, how they would like the rounds to be conducted, and differences of opinion between medical students and postgraduates.</p> <p>Methods</p> <p>A cross-sectional study was conducted on a total of 134 trainees in Internal Medicine, comprising medical students, interns, residents and fellows, who were asked to fill in a structured, self-designed questionnaire. Most of the responses required a rating on a scale of 1-5 (1 being highly unsatisfactory and 5 being highly satisfactory).</p> <p>Results</p> <p>Teaching of clinical skills and bedside teaching received the lowest overall mean score (Mean ± SD 2.48 ± 1.02 and 2.49 ± 1.12 respectively). They were rated much lower by postgraduates as compared to students (p < 0.001). All respondents felt that management of patients was the aspect best covered by the current ward rounds (Mean ± SD 3.71 ± 0.72). For their desired ward rounds, management of patients received the highest score (Mean ± SD 4.64 ± 0.55), followed by bedside examinations (Mean ± SD 4.60 ± 0.61) and clinical skills teaching (Mean ± SD 4.50 ± 0.68). The postgraduates desired a lot more focus on communication skills, counselling and medical ethics as compared to students, whose primary focus was teaching of bedside examination and management. A majority of the respondents (87%) preferred bedside rounds over conference room rounds. Even though the duration of rounds was found to be adequate, a majority of the trainees (68%) felt there was a lack of individual attention during ward rounds.</p> <p>Conclusions</p> <p>This study highlights important areas where ward rounds need improvement in order to maximize their benefit to the learners. There is a need to modify the current state of ward rounds in order to address the needs and expectations of trainees.</p

Antimicrobial resistance among migrants in Europe: a systematic review and meta-analysis

BACKGROUND: Rates of antimicrobial resistance (AMR) are rising globally and there is concern that increased migration is contributing to the burden of antibiotic resistance in Europe. However, the effect of migration on the burden of AMR in Europe has not yet been comprehensively examined. Therefore, we did a systematic review and meta-analysis to identify and synthesise data for AMR carriage or infection in migrants to Europe to examine differences in patterns of AMR across migrant groups and in different settings. METHODS: For this systematic review and meta-analysis, we searched MEDLINE, Embase, PubMed, and Scopus with no language restrictions from Jan 1, 2000, to Jan 18, 2017, for primary data from observational studies reporting antibacterial resistance in common bacterial pathogens among migrants to 21 European Union-15 and European Economic Area countries. To be eligible for inclusion, studies had to report data on carriage or infection with laboratory-confirmed antibiotic-resistant organisms in migrant populations. We extracted data from eligible studies and assessed quality using piloted, standardised forms. We did not examine drug resistance in tuberculosis and excluded articles solely reporting on this parameter. We also excluded articles in which migrant status was determined by ethnicity, country of birth of participants' parents, or was not defined, and articles in which data were not disaggregated by migrant status. Outcomes were carriage of or infection with antibiotic-resistant organisms. We used random-effects models to calculate the pooled prevalence of each outcome. The study protocol is registered with PROSPERO, number CRD42016043681. FINDINGS: We identified 2274 articles, of which 23 observational studies reporting on antibiotic resistance in 2319 migrants were included. The pooled prevalence of any AMR carriage or AMR infection in migrants was 25·4% (95% CI 19·1-31·8; I2 =98%), including meticillin-resistant Staphylococcus aureus (7·8%, 4·8-10·7; I2 =92%) and antibiotic-resistant Gram-negative bacteria (27·2%, 17·6-36·8; I2 =94%). The pooled prevalence of any AMR carriage or infection was higher in refugees and asylum seekers (33·0%, 18·3-47·6; I2 =98%) than in other migrant groups (6·6%, 1·8-11·3; I2 =92%). The pooled prevalence of antibiotic-resistant organisms was slightly higher in high-migrant community settings (33·1%, 11·1-55·1; I2 =96%) than in migrants in hospitals (24·3%, 16·1-32·6; I2 =98%). We did not find evidence of high rates of transmission of AMR from migrant to host populations. INTERPRETATION: Migrants are exposed to conditions favouring the emergence of drug resistance during transit and in host countries in Europe. Increased antibiotic resistance among refugees and asylum seekers and in high-migrant community settings (such as refugee camps and detention facilities) highlights the need for improved living conditions, access to health care, and initiatives to facilitate detection of and appropriate high-quality treatment for antibiotic-resistant infections during transit and in host countries. Protocols for the prevention and control of infection and for antibiotic surveillance need to be integrated in all aspects of health care, which should be accessible for all migrant groups, and should target determinants of AMR before, during, and after migration. FUNDING: UK National Institute for Health Research Imperial Biomedical Research Centre, Imperial College Healthcare Charity, the Wellcome Trust, and UK National Institute for Health Research Health Protection Research Unit in Healthcare-associated Infections and Antimictobial Resistance at Imperial College London