206 research outputs found

    E-learning : technology in teaching logistics

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    The impact of data, information, and knowledge on teaching and learning is more important than ever. The dynamic development of technology based on digitization, robotization, and networking is transforming the world of business and science, and universities play an extremely important role in this process. The digitization of the socioeconomic environment forces changes towards technologization. The educational process should be substantive and organized in such a way that students not only learn about technological solutions but also have the skills and competences to apply knowledge in practice. An example of such activity is the teaching and learning of logistics with the use of distance learning methods and techniques. The aim of this article is to identify the possibilities of using e-learning in teaching logistics to face the challenges of the future. The information is based on secondary and primary sources. This article uses qualitative and quantitative mixed research methods. On the one hand, books and reports, scientific articles, and Internet sources were examined during the desk research phase. On the other hand, the use of e-learning in teaching logistics at selected universities in Poland was tested using the diagnostic survey method, which involved computer-assisted web interviewing (CAWI). The collected material showed the need for using e-learning in teaching logistics. Logistics companies need employees with digital competences and skills. Therefore, using new technologies already in the education process is justified. Learning with the use of remote methods and techniques represents the essential components of the requirements of the university's technological ecosystem. The analysis of the material leads to the conclusion that the implementation of technology into the didactic process as such is not sufficient. Adoption of modern methods and technologies requires a comprehensive approach to managing educational units. It is important that the propagation of modern forms of teaching has the understanding and support of users who are an inherent component of the educational ecosystem structure

    Smart logistics : sustainable technological innovations in customer service at the last-mile stage : the Polish perspective

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    The present day is marked by the economic expansiveness of societies and the adoption and adaptation of intelligent technologies. In this hyper-world, customers expect a personalized offer enhanced with customized service, which results in the introduction of sustainable and intelligent solutions—among other services. What becomes important is not so much the "Primum non nocere" of creation as much as the "go smart to the future" in creating. The smart logistics concept is a representation of this trend. The subject of the article is an analysis of the impact of the application of the smart idea in the field of sustainable development on changes in logistics in customer service at the last-mile stage. The source of this article is exploratory research of secondary sources, including books, articles, and reports, which has been subjected to a critical content analysis. The obtained results made it possible to design and implement an explanatory study of online-buying habits of people based on the CAWI (Computer Assisted Web Interview) methodology. The collected material has become the basis for the authors to indicate the applicability of smart logistics in the field of last-mile logistics, which can be used by researchers and training institutions in the field of professionalization of management of intelligent logistics processes in customer service at the last-mile stage. The last-mile service in logistics involves reaching the largest possible number of recipients, however, it has a negative impact on the natural environment, which, of course, contradicts the concept of sustainable development, including trends that are noticeable in the logistics market, customers, and in the law. Hence, it is important to look for solutions that allow us to achieve the appropriate level of customer service in the last mile, but at the same time, take care of the natural environment. The study was narrowed down to the Polish perspective due to the growing demand for last-mile logistics services. Moreover, Poland is still a country where the concept of sustainable development is not fully understood and used. The research allowed us to indicate the directions of development of the last-mile service processes by considering the technological innovations that may support the application of the concept of sustainable development

    Long-Term Effects of Pedicle Clamping during Major Hepatectomy for Colorectal Liver Metastases

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    The use of the Pringle maneuver (PM) varies widely among surgical departments. Its use depends on the operator and type of liver resection. The aim of this study was to determine the impact of the PM on patient outcomes when undergoing major liver resections. This retrospective study comprised 179 colorectal liver metastasis patients from two liver centers from Leeds and Warsaw. Only right or right extended hepatectomies with negative oncological margins were included. The primary outcome measure was the 5-year overall survival (OS). The PM was applied during 60 (33.5%) major hepatectomies included in the study and was associated with a higher peak 3-day postoperative bilirubin concentration (p = 0.002), yet not with the peak 3-day alanine aminotransferase activity (p = 0.415). The 5-year OS after liver resections with the PM and without the PM were 55.0% and 33.4%, respectively (p = 0.019). Following stratification by the Tumor Burden Score, after resections with the use of the PM, superior survival was particularly found in the subgroup of patients at intermediate risk of recurrence (p = 0.004). However, the use of the PM had no significant effect on the 5-year overall survival following adjustment for the confounding effect of the carcinoembryonic antigen concentration (p = 0.265). The use of the PM had no negative effects on the long-term outcomes in patients undergoing major, oncologically radical liver resections for colorectal metastases

    Hybridization of Advanced Oxidation Processes with Membrane Separation for Treatment and Reuse of Industrial Laundry Wastewater

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    A new attempt to treat and reuse the industrial laundry wastewater using biological treatment followed by advanced oxidation processes (AOPs) and membrane separation is presented. Three various configurations of the hybrid systems were investigated: (1) biological treatment in a Moving Bed Biofilm Reactor (MBBR) ñ€“ photocatalysis with suspended TiO2 P25, enhanced with in situ generated O3 ñ€“ ultrafiltration (UF) ñ€“ nanofiltration (NF); (2) biological treatment in MBBRñ€“ photocatalysis with immobilized TiO2 P25, enhanced with in situ generated O3 ñ€“ UF - NF; (3) biological treatment in MBBR ñ€“ photolysis/ozonation (with in situ generated O3) ñ€“ UF ñ€“ NF. For comparison purpose the wastewater was additionally treated in the MBBR ñ€“ UF ñ€“ NF mode (4). Application of AOPs contributed to the UF membrane fouling mitigation during treatment of the biologically pretreated laundry wastewater. The highest improvement of the UF permeate flux was found in case of the MBBR effluent treated with application of the immobilized TiO2 bed which was attributed to the highest efficiency of mineralization observed for that system. Since the applied wastewater contained significant amounts of inorganic ions, mainly Na+ and Cl-, the NF as the final polishing step was proposed. The quality of NF permeate was independent on the AOP mode applied and, moreover, significantly higher than the quality of water currently used in the laundry. It was concluded that the NF permeate could be recycled to any stage of the laundry system. Taking into consideration that application of TiO2 increases the overall treatment costs and that although the O3/UV pretreatment is less efficient than photocatalysis, it still allows to improve the UF permeate flux for ca. 35% compared to the direct UF of the MBBR effluent, the MBBR ñ€“ UV/O3 ñ€“ UF ñ€“ NF system was proposed as the most beneficial configuration for the treatment and reuse of the industrial laundry wastewater

    BezpieczeƄstwo informacji i biznesu: zagadnienia wybrane

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    Praca recenzowana / peer-reviewed paperPrezentowane wydawnictwo stanowi plon obrad międzynarodowej konferencji naukowej zorganizowanej w dniach 12–13 paĆșdziernika 2008 roku przez Katedrę Zarządzania Informacją, dziaƂającą w ramach WydziaƂu Ekonomii i Zarządzania, oraz, jak juĆŒ wspomniano, przez Międzynarodowe Stowarzyszenie „Edukacja dla Obronnoƛci i BezpieczeƄstwa”. Ambicją organizatorĂłw konferencji byƂo wƂączenie w tok dyskusji licznych przedstawicieli organĂłw administracji paƄstwa i samorządu, praktyki gospodarczej, nauki, mediĂłw oraz studentĂłw, zarĂłwno z kraju, jak i z zagranicy

    Les droits disciplinaires des fonctions publiques : « unification », « harmonisation » ou « distanciation ». A propos de la loi du 26 avril 2016 relative à la déontologie et aux droits et obligations des fonctionnaires

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    The production of tt‟ , W+bb‟ and W+cc‟ is studied in the forward region of proton–proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98±0.02 fb−1 . The W bosons are reconstructed in the decays W→ℓΜ , where ℓ denotes muon or electron, while the b and c quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions.The production of tt‟t\overline{t}, W+bb‟W+b\overline{b} and W+cc‟W+c\overline{c} is studied in the forward region of proton-proton collisions collected at a centre-of-mass energy of 8 TeV by the LHCb experiment, corresponding to an integrated luminosity of 1.98 ±\pm 0.02 \mbox{fb}^{-1}. The WW bosons are reconstructed in the decays W→ℓΜW\rightarrow\ell\nu, where ℓ\ell denotes muon or electron, while the bb and cc quarks are reconstructed as jets. All measured cross-sections are in agreement with next-to-leading-order Standard Model predictions

    Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

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    Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p<0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (<1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (<1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline

    The Comet Interceptor Mission

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    Here we describe the novel, multi-point Comet Interceptor mission. It is dedicated to the exploration of a little-processed long-period comet, possibly entering the inner Solar System for the first time, or to encounter an interstellar object originating at another star. The objectives of the mission are to address the following questions: What are the surface composition, shape, morphology, and structure of the target object? What is the composition of the gas and dust in the coma, its connection to the nucleus, and the nature of its interaction with the solar wind? The mission was proposed to the European Space Agency in 2018, and formally adopted by the agency in June 2022, for launch in 2029 together with the Ariel mission. Comet Interceptor will take advantage of the opportunity presented by ESA’s F-Class call for fast, flexible, low-cost missions to which it was proposed. The call required a launch to a halo orbit around the Sun-Earth L2 point. The mission can take advantage of this placement to wait for the discovery of a suitable comet reachable with its minimum ΔV capability of 600 ms−1. Comet Interceptor will be unique in encountering and studying, at a nominal closest approach distance of 1000 km, a comet that represents a near-pristine sample of material from the formation of the Solar System. It will also add a capability that no previous cometary mission has had, which is to deploy two sub-probes – B1, provided by the Japanese space agency, JAXA, and B2 – that will follow different trajectories through the coma. While the main probe passes at a nominal 1000 km distance, probes B1 and B2 will follow different chords through the coma at distances of 850 km and 400 km, respectively. The result will be unique, simultaneous, spatially resolved information of the 3-dimensional properties of the target comet and its interaction with the space environment. We present the mission’s science background leading to these objectives, as well as an overview of the scientific instruments, mission design, and schedule

    A study of CP violation in B-+/- -> DK +/- and B-+/- -> D pi(+/-) decays with D -> (KSK +/-)-K-0 pi(-/+) final states

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    A first study of CP violation in the decay modes B±→[KS0K±π∓]Dh±B^\pm\to [K^0_{\rm S} K^\pm \pi^\mp]_D h^\pm and B±→[KS0K∓π±]Dh±B^\pm\to [K^0_{\rm S} K^\mp \pi^\pm]_D h^\pm, where hh labels a KK or π\pi meson and DD labels a D0D^0 or D‟0\overline{D}^0 meson, is performed. The analysis uses the LHCb data set collected in pppp collisions, corresponding to an integrated luminosity of 3 fb−1^{-1}. The analysis is sensitive to the CP-violating CKM phase Îł\gamma through seven observables: one charge asymmetry in each of the four modes and three ratios of the charge-integrated yields. The results are consistent with measurements of Îł\gamma using other decay modes
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